Potential conflict of interest: Nothing to report.
MicroRNA-216a/217-induced epithelial-mesenchymal transition targets PTEN and SMAD7 to promote drug resistance and recurrence of liver cancer
Article first published online: 25 JUN 2013
Copyright © 2013 by the American Association for the Study of Liver Diseases
Volume 58, Issue 2, pages 629–641, August 2013
How to Cite
Xia, H., Ooi, L. L. P.J. and Hui, K. M. (2013), MicroRNA-216a/217-induced epithelial-mesenchymal transition targets PTEN and SMAD7 to promote drug resistance and recurrence of liver cancer. Hepatology, 58: 629–641. doi: 10.1002/hep.26369
This work was supported by grants from the SingHealth Foundation, the National Medical Research Council, the Biomedical Research Council of Singapore, and The Singapore Millennium Foundation. The authors thank the NCCS Tissue Repository for providing the tissue specimens for this study, Prof. S.S. Jiang from Sun Yat-sen University (Guangzhou, China) for providing the pLL3.7-miR-control vectors, and Addgene for the plasmids.
- Issue published online: 29 JUL 2013
- Article first published online: 25 JUN 2013
- Accepted manuscript online: 7 MAR 2013 12:05PM EST
- Manuscript Accepted: 22 FEB 2013
- Manuscript Received: 27 SEP 2012
- 7Cancer stem cells and epithelial-to-mesenchymal transition (EMT)-phenotypic cells: are they cousins or twins? Cancers 2011;3:716-729., , , .
- 23Loss of phosphatase and tensin homolog enhances cell invasion and migration through aKT/Sp-1 transcription factor/matrix metalloproteinase 2 activation in hepatocellular carcinoma and has clinicopathologic significance. Hepatology 2011;53:1558-1569., , , , , .