These authors contributed equally to this work.
PROX1 promotes hepatocellular carcinoma metastasis by way of up-regulating hypoxia-inducible factor 1α expression and protein stability
Article first published online: 29 JUL 2013
Copyright © 2013 by the American Association for the Study of Liver Diseases
Volume 58, Issue 2, pages 692–705, August 2013
How to Cite
Liu, Y., Zhang, J.-B., Qin, Y., Wang, W., Wei, L., Teng, Y., Guo, L., Zhang, B., Lin, Z., Liu, J., Ren, Z.-G., Ye, Q.-H. and Xie, Y. (2013), PROX1 promotes hepatocellular carcinoma metastasis by way of up-regulating hypoxia-inducible factor 1α expression and protein stability. Hepatology, 58: 692–705. doi: 10.1002/hep.26398
Potential conflict of interest: Nothing to report.
Supported by grants from National Key Project for Infectious Diseases (2012ZX10002-006, 2012ZX10004-503, 2012ZX10002012-003), National Basic Research Program (2009CB521701, 2012CB519002), Natural Science Foundation of China (31071143, 31170148, 30872505, 81071993, 81172275), and Shanghai Municipal R&D Grant (11DZ2291900, GWDTR201216).
- Issue published online: 29 JUL 2013
- Article first published online: 29 JUL 2013
- Accepted manuscript online: 16 MAR 2013 02:16AM EST
- Manuscript Accepted: 10 MAR 2013
- Manuscript Received: 18 JAN 2013
Additional Supporting Information may be found in the online version of this article.
|hep26398-sup-0001-suppfig1.tif||5562K||Supporting Information Figure 1|
|hep26398-sup-0002-suppfig2.tif||3731K||Supporting Information Figure 2|
|hep26398-sup-0003-suppfig3.tif||1200K||Supporting Information Figure 3|
|hep26398-sup-0004-suppfig4.tif||1652K||Supporting Information Figure 4|
|hep26398-sup-0005-suppfig5.tif||1219K||Supporting Information Figure 5|
|hep26398-sup-0006-supptab1.doc||34K||Table S1. Clinicopathologic features of patients from two cohorts|
|hep26398-sup-0007-supptab2.doc||35K||Table S2. Primary antibodies for western blot, immunohistochemistry and co-immunoprecipitation|
|hep26398-sup-0008-supptab3.doc||80K||Table S3. Comparison of clinicopathologic profiles between HCC patients of high PROX1 level and low PROX1 level in cohort 1|
|hep26398-sup-0009-supptab4.doc||39K||Table S4. Prognostic values of variables for overall survival, recurrence and early recurrence|
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