Additional Supporting Information may be found in the online version of this article.

hep26567-sup-0001-suppinfo.doc33KSupporting Information
hep26567-sup-0002-suppfig1.tif333KSupplementary Figure 1: Differences in susceptibility to HCV infection of Huh-7.5 compared to HuH6 cells. The susceptibility of Huh-7.5 and HuH6 cells to HCVcc particles was calculated. To this end, TCID50 titers of given HCVcc particles determined in Huh-7.5 cells were divided by the titer observed after inoculation of HuH6 cells with the same virus stock. Mean values and standard deviation of four independent experiments are given.
hep26567-sup-0003-suppfig2.tif1010KSupplementary Figure 2: CLDN6 expression in human liver biopsies. The CLDN6 expression in human liver biopsies was analyzed in regard to (A) HCV genotype of the infected patient, (B) fibrosis stage rated in METAVIR F groups, (C) disease duration and (D) gender of the patients.
hep26567-sup-0004-supptable1.tif1015KSupplementary Table 1: Data of patients included in this study.
hep26567-sup-0005-supptable2.tif995KSupplementary Table 2: SiRNA sequences used for knock-down of HCV entry receptors.
hep26567-sup-0006-supptable3.tif795KSupplementary Table 3: Primers and Probes used for qRT-PCR. mRNA specific qRT-PCR primers and probes used for expression analysis of HCV entry receptors. qRT-PCR analysis was performed using a one–step RT-PCR LightCycler 480 RNA Master Hydrolysis Probes Kit (Roche, Mannheim, Germany) and a LightCycler 480 machine (Roche).

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