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Additional Supporting Information may be found in the online version of this article.

FilenameFormatSizeDescription
hep26589-sup-0001-supptabs.doc94KSupporting Tables
hep26589-sup-0002-suppfig1.tif119KSupporting Figure 1. Liver-specific deletion of lipin-1 exacerbates alcoholic fatty liver in mice. Wild-type (WT) or lipin-1LKO (LKO) mice were pair-fed either a control LF diet or an ethanol-containing diet for 4-wks. (A) Relative mRNA levels of hepatic fibronectin and CD68. (B) Relative protein levels of PGC-1α. Results are expressed as means±SEM (n=4-11 mice). Means without a common letter differ, p< 0.05
hep26589-sup-0003-suppfig2.tif119KSupporting Figure 2. Mice were fed as described in Fig.1. (A) Plasma level of LCN-2. (B) Circulating level of SAA-1. Results are expressed as means±SEM (n=4-11 mice). Means without a common letter differ, p< 0.05
hep26589-sup-0004-suppfig3.tif144KSupporting Figure 3. Mice were fed as described in Fig.1. (A) Relative mRNA levels of hepatic FAS, SCD1 and GPAT1. (B) Relative mRNA levels of hepatic CD36, ApoB, MTP and c-Met. Results are expressed as means±SEM (n=4-11 mice). Means without a common letter differ, p< 0.05

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