These authors contributed equally to this work.
Protein kinase C (PKC) participates in acetaminophen hepatotoxicity through c-jun-N-terminal kinase (JNK)-dependent and -independent signaling pathways
Article first published online: 3 MAR 2014
Copyright © 2014 by the American Association for the Study of Liver Diseases
Volume 59, Issue 4, pages 1543–1554, April 2014
How to Cite
Saberi, B., Ybanez, M. D., Johnson, H. S., Gaarde, W. A., Han, D. and Kaplowitz, N. (2014), Protein kinase C (PKC) participates in acetaminophen hepatotoxicity through c-jun-N-terminal kinase (JNK)-dependent and -independent signaling pathways. Hepatology, 59: 1543–1554. doi: 10.1002/hep.26625
See Editorial on Page 1229
This work was supported by NIH grants DK067215 (to N.K.), AA016911 (to D.H.) and the USC Research Center for Liver Diseases (P30 DK048522) cell culture, cell, and tissue imaging (S10 RR022508) and analytical/metabolic/instrumentation cores.
Potential conflict of interest: Dr. Kaplowitz consults for GlaxoSmithKline, Pfizer, Merck, Novartis, Bristol-Myers Squibb, Johnson & Johnson, Hepregen, Daiichi Sankyo, Isis, Enanta, Takeda, Otsuka, Roche, and Sanofi-Aventis. Dr. Gaarde owns stock in Isis.
- Issue published online: 24 MAR 2014
- Article first published online: 3 MAR 2014
- Accepted manuscript online: 19 JUL 2013 05:35AM EST
- Manuscript Accepted: 3 JUL 2013
- Manuscript Received: 27 MAR 2013
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