Diagnosis of sinusoidal obstruction syndrome by positron emission tomography/computed tomography: Report of two cases treated by defibrotide

Authors

  • Mathieu Gauthé,

    Corresponding author
    1. Institut Curie, Service de Médecine Nucléaire, Department of Nuclear Medicine, Saint-Cloud, France
    • Address reprint requests to: Mathieu Gauthé, Institut Curie, Service de Médecine Nucléaire, 35 rue Dailly, Saint-Cloud, F-92210, France. E-mail: mathieu.gauthe@curie.fr; fax: +33147113378.

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  • Laurence Bozec,

    1. Institut Curie, Service d'Oncologie Médicale, Department of Medical Oncology, Saint-Cloud, France
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  • Pierre Bedossa

    1. Départment d'Anatomie Pathologique Beaujon-Bichat, Inserm U773, Université Paris-Diderot, Hôpital Beaujon, Clichy, France
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  • Potential conflict of interest: Nothing to report.

Abstract

Sinusoidal obstruction syndrome (SOS) is a potentially fatal liver injury that mainly occurs after myeloablative chemotherapy. We report two cases of SOS investigated by 18F-fluorodeoxyglucose positron emission tomography/computed tomography and treated with defibrotide. (Hepatology 2014;60:1789–1791)

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