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References

  • 1
    Kaplan MM. Primary biliary cirrhosis. Adv Intern Med 1987; 32: 359377.
  • 2
    Mackay IR. Primary biliary cirrhosis showing high titre of autoantibody: report of a case. N Engl J Med 1958; 258: 185187.
  • 3
    Walker JG, Doniach D, Roitt IM, Sherlock S. Serological tests in diagnosis of primary biliary cirrhosis. Lancet 1965; 1: 827831.
  • 4
    Berg PA, Doniach D, Roitt IM. Mitochondrial antibodies in primary biliary cirrhosis. I. Localization of the antigen to mitochondrial membranes. J Exp Med 1967; 126: 277290.
  • 5
    Gershwin ME, Mackay IR. Primary biliary cirrhosis: paradigm or paradox for autoimmunity. Gastroenterology 1991; 100: 822833.
  • 6
    Yeaman SJ, Banner DJ, Mutimer DJ, Fussey SPM, James OFW, Bassendine MF. Primary biliary cirrhosis: identification of two major M2 mitochondrial autoantigens. Lancet 1988; 1: 10671070.
  • 7
    Van de Water J, Gershwin ME, Leung P, Ansari A, Coppel RL. The auto-epitope of the 74 kD mitochondrial autoantigen of primary biliary cirrhosis corresponds to the functional site of dihydrolipoamide acetyltransferase. J Exp Med 1988; 167: 17911799.
  • 8
    Fussey SPM, Guest JR, James OFW, Bassendine MF, Yeaman SJ. Identification and analysis of the major M2 autoantigens in primary biliary cirrhosis. Proc Natl Acad Sci U S A 1988; 85: 86548658.
  • 9
    Fregeau DR, Davis PA, Danner DJ, Ansari A, Coppel RL, Dickson ER, Gershwin ME. Antimitochondrial antibodies of primary biliary cirrhosis recognize dihydrolipoamide acyltransferase and inhibit enzyme function of the branched chain α-ketoacid dehydrogenase complex. J Immunol 1989; 142: 38153820.
  • 10
    Surh CD, Roche TE, Danner DJ, Ansari A, Coppel RL, Prindiville T, Dickson ER. et al. Antimitochondrial autoantibodies in primary biliary cirrhosis recognize cross-reactive epitope(s) on protein X and dihydrolipoamide acetyltransferase of pyruvate dehydrogenase complex. Hepatology 1989; 10: 127133.
  • 11
    Fregeau DR, Roche TE, Davis PA, Coppel RL, Gershwin ME. Inhibition of pyruvate dehydrogenase complex activity by autoantibodies specific for E1α, a non-lipoic acid containing mitochondrial enzyme. J Immunol 1990; 144: 16711676.
  • 12
    Fregeau DR, Prindiville T, Coppel RL, Kaplan M, Dickson ER, Gershwin ME. Inhibition of α-ketoglutarate dehydrogenase activity by a distinct population of autoantibodies recognizing dihydrolipoamide succinyltransferase in primary biliary cirrhosis. Hepatology 1990; 11: 975981.
  • 13
    Mutimer DJ, Fussey SP, Yeaman SJ, Kelly PJ, James OF, Bassendine MF. Frequency of IgG and IgM autoantibodies to four specific M2 mitochondrial autoantigens in primary biliary cirrhosis. Hepatology 1989; 10: 403407.
  • 14
    Leung PSC, Iwayama T, Prindiville T, Chuang DT, Ansari AA, Wynn RM, Dickson R. et al. Use of designer recombinant mitochondrial antigens in the diagnosis of primary biliary cirrhosis. Hepatology 1992; 15: 367372.
  • 15
    Van de Water J, Cooper A, Surh CD, Coppel R, Danner D, Ansari A, Dickson R. et al. Detection of autoantibodies to recombinant mitochondrial proteins in patients with primary biliary cirrhosis. N Engl J Med 1989; 320: 13771380.
  • 16
    Iwayama T, Leung PSC, Rowley M, Munoz S, Nishioka M, Nakagawa T, Dickson ER. et al. Comparative immunoreactive profiles of Japanese and American patients with primary biliary cirrhosis against mitochondrial autoantigens. Int Arch Allergy Immunol 1992; 99: 2833.
  • 17
    Leung PSC, Manns MP, Gershwin ME. Inflammatory hepatobiliary cirrhosis. In: RichRR. ed. Clinical Immunology. Principles and Practice. St. Louis: Mosby-Year Book, 1996: 14291443.
  • 18
    Moteki S, Leung PSC, Dickson ER, Van Thiel DH, Galperin C, Buch T, Alar con-Segovia D. et al. Epitope mapping and reactivity of autoantibodies to the E-2 component of 2-oxoglutarate dehydrogenase complex (OGDC-E2) in primary biliary cirrhosis using recombinant OGDC-E2. Hepatology 1996; 23: 436444.
  • 19
    Surh CD, Coppel RL, Gershwin ME. Structural requirement for autoreac-tivity on human pyruvate dehydrogenase-E2, the major autoantigen of primary biliary cirrhosis. J Immunol 1990; 144: 33673374.
  • 20
    Leung PSC, Chuang DT, Wynn RM, Cha S, Danner DJ, Ansari A, Coppel RL. et al. Autoantibodies to BCOADC-E2 in patients with primary biliary cirrhosis recognize a conformational epitope. Hepatology 1995; 22: 505513.
  • 21
    Gershwin ME, Mackay IR, Sturgess A, Coppel RL. Identification and specificity of a cDNA encoding the 70 kD mitochondrial antigen recognized in primary biliary cirrhosis. J Immunol 1987; 138: 35253531.
  • 22
    Coppel RL, McNeilage LJ, Surh CD, Van de Water J, Spithill TW, Whit-tingham S, Gershwin ME. Primary structure of the human M2 mitochondrial autoantigen of primary biliary cirrhosis: dihydrolipoamide acetyltransferase. Proc Natl Acad Sci U S A 1988; 85: 73177321.
  • 23
    Griffin TA, Lau KS, Chuang DT. Characterization and conservation of the inner E2 core domain structure of branched-chain α-keto acid dehydrogenase complex from bovine liver: construction of a cDNA encoding the entire transacylase (E2b) precursor. J Biol Chem 1988; 263: 1400814014.
  • 24
    Danner DJ, Litwer S, Herring WJ, Pruckler J. Construction and nucleotide sequence of a cDNA encoding the full length preprotein for human branched chain acetyltransferase. J Biol Chem 1989; 264: 77427746.
  • 25
    Ho L, Wexler ID, Liu TC, Thekkumkara TJ, Patel MS. Characterization of cDNAs encoding human pyruvate dehydrogenase α subunit. Proc Natl Acad Sci U S A 1989; 86: 53305334.
  • 26
    Surh CD, Danner DJ, Ahmed A, Coppe RL, Mackay IR, Dickson ER, Gershwin ME. Reactivity of primary biliary cirrhosis sera with a human fetal liver cDNA clone of branched-chain α-ketoacid dehydrogenase dihydrolipoamide acyltransferase, the 52 kD mitochondrial autoantigen. Hepatology 1989; 9: 6368.
  • 27
    Iwayama T, Leung PSC, Coppel RL, Roche TE, Patel MS, Mizushima Y, Nakagawa T. et al. Specific reactivity of recombinant human PDC-E1α in primary biliary cirrhosis. J Autoimmun 1991; 4: 769778.
  • 28
    Williamson JM, Chalmers DM, Clayden AD, Dixon M-F, Ruddell WS, Losowosky MS. Primary biliary cirrhosis and chronic active hepatitis: an examination of clinical, biochemical and histological features in differential diagnosis. J Clin Pathol 1985; 38: 10071012.
  • 29
    Leung PSC, Iwayama T, Coppel RL, Gershwin ME. Site-directed mutagen-esis of lysine within the immunodominant autoepitope of PDC-E2. Hepatology 1990; 12: 13211328.
  • 30
    Kemp DJ, Coppel RL, Cowman AF, Saint RB, Brown GV, Anders RF. Expression of plasmodium falciparum blood-stage antigens in Escherichia coli: detection with antibodies from immune humans. Proc Natl Acad Sci USA 1983; 80: 37873791.
  • 31
    Leung PSC, Gershwin ME. Cloning and identification of autoantigens. Immunomethods 1992; 1: 149157.
  • 32
    Nakano K, Matuda S, Yamanaka T, Tsubouchi H, Nakagawa S, Titani K, Ohta S. et al. Purification and molecular cloning of succinyltransferase of the rat α-ketoglutarate dehydrogenase complex. J Biol Chem 1991; 266: 1901319017.
  • 33
    Griffin TA, Wynn RM, Chuang DT. Expression and assembly of mature apotransacylase (E2b) of bovine branched chain α-keto acid dehydrogenase complex in Escherichia coli. J Biol Chem 1990; 265: 1210412110.
  • 34
    Griffin TA, Chuang DT. Genetic reconstruction and characterization of the recombinant transacylase (E2b) component of bovine branched chain α-keto acid dehydrogenase complex. J Biol Chem 1990; 265: 1317413180.
  • 35
    Laemmli UK. Cleavage of structural proteins during assembly of the head of bacteriophage T4. Nature 1970; 227: 680685.
  • 36
    Schneider WC, Hogeboom GH. Intracellular distribution of enzymes: further studies on the distribution of cytochrome in rat liver homogenate. J Biol Chem 1950; 183: 123128.
  • 37
    Towbin H, Staeheim T, Gordon J. Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications. Proc Natl Acad Sci U S A 1979; 76: 43504354.
  • 38
    Berg PA, Klein R. Mitochondrial antigens and autoantibodies: from anti-Mi to anti-M9. Klin Wochenschr 1986; 64: 897909.
  • 39
    Sudin U. Antibody binding and inhibition of pyruvate dehydrogenase (PDH) in sera from patients with primary biliary cirrhosis. Clin Exp Immunol 1990; 81: 238243.
  • 40
    Tsuruya T. Detection of anti-pyruvate dehydrogenase complex antibody in primary biliary cirrhosis by an enzyme-linked immunosorbent assay. Gastroenterol Jpn 1990; 25: 471477.
  • 41
    Toh BH. Smooth muscle autoantibodies and autoantigens. Clin Exp Immunol 1979; 38: 621628.
  • 42
    Rizzeto M, Swana G, Doniach D. Microsomal antibodies in active chronic hepatitis and other disorders. Clin Exp Immunol 1973; 15: 331344.
  • 43
    Manns MP, Griffin KJ, Sullivan KF, Johnson EF. LKM-1 autoantibodies recognize a short linear sequence in P450 IID6, a cytochrome P-450 monooxygenase. J Clin Invest 1991; 88: 13701378.
  • 44
    Maeda T, Loveland BE, Rowley MJ, Mackay IR. Autoantibody against dihydrolipoamide dehydrogenase, the E3 subunit of the 2-oxoacid dehydrogenase complexes: significance for primary biliary cirrhosis. Hepatology 1991; 14: 994999.