SEARCH

SEARCH BY CITATION

References

  • 1
    Sasse D, Spornitz UM, Maly IP. Liver architecture. Enzyme 1992; 46: 836.
  • 2
    Jungermann K, Katz N. Functional specializations of different hepatocyte populations. Physiol Rev 1989; 69: 708764.
  • 3
    Gumucio JJ. Hepatocyte heterogeneity: the coming of age from the description of a biological curiosity to a partial understanding of its physiological meaning and regulation. Hepatology 1989; 9: 154160.
  • 4
    Haüssinger D, Lamers WH, Moorman AFM. Hepatocyte heterogeneity in the metabolism of amino acids and ammonia. Enzyme 1992; 46: 7293.
  • 5
    Gebhardt R. Metabolic zonation of the liver: regulation and implications for liver function. Pharmacol Ther 1992; 53: 275354.
  • 6
    Feldmann G, Scoazec J-Y, Racine L, Bernuau D. Functional hepatocellular heterogeneity for the production of plasma proteins. Enzyme 1992; 46: 139154.
  • 7
    Jungermann K. Zonal liver cell heterogeneity. Enzyme 1992; 46: 57.
  • 8
    Gumucio JJ, Bilir BM, Moseley RH, Berkowitz CM. The biology of the liver cell plate. In: AriasIM, BoyerJL, FaustoN, JakobyWB, SchachterDA, ShafritzDA, eds. The liver: biology and pathobiology, 3rd ed. New York: Raven, 1994: 11431163.
  • 9
    Cohen PJ. Changes in the distribution of succinic dehydrogenase within the rat hepatic lobule after ligation of the common bile duct. Anat Rec 1965; 153: 429444.
  • 10
    Nuber R, Teutsch HF, Sasse D. Metabolic zonation in thioacetamide-induced liver cirrhosis. Histochemistry 1980; 69: 277288.
  • 11
    Van Noorden CJF, Frederiks WM, Aronson DC, Marx F, Bosch K, Jonges GN, Vogels IMC. et al. Changes in the acinar distribution of some enzymes involved in the carbohydrate metabolism in rat liver parenchyma after experimentally induced cholestasis. Virchows Arch (Cell Pathol) 1987; 52: 501511.
  • 12
    Sokal EM, Trivedi P, Portmann B, Mowat AP. Adaptive changes of metabolic zonation during the development of cirrhosis in growing rats. Gastroenterology 1990; 99: 785792.
  • 13
    Sokal EM, Mostin J, Buts J-P. Liver metabolic zonation in rat biliary cirrhosis: distribution is reverse of that in toxic cirrhosis. Hepatology 1992; 15: 904908.
  • 14
    Gebhardt R, Reichen J. Changes in the distribution and activity of glutamine-synthetase in carbon tetrachloride-induced cirrhosis in the rat: potential role in hyperammonemia. Hepatology 1994; 20: 684691.
  • 15
    Sano K, Fujioka Y, Nagashima K, Hashizume T, Komori M, Kitada M, Kamataki T. et al. Distributional variation of P-450 immunoreactive hepatocytes in human liver disorders. Hum Pathol 1989; 20: 10151020.
  • 16
    Ratanasavanh D, Beaune P, Morel F, Flinois J-P, Guengerich FP, Guillouzo A. Intralobular distribution and quantitation of cytochrome P-450 enzymes in human liver as a function of age. Hepatology 1991; 13: 11421151.
  • 17
    Palmer CNA, Coates PJ, Davies SE, Shephard EA, Phillips IR. Localization of cytochrome P-450 gene expression in normal and diseased human liver by in situ hybridization of wax-embedded archival material. Hepatology 1992; 16: 682687.
  • 18
    Tournier I, Bernuau D, Poliard A, Schoevaert D, Feldmann G. Detection of albumin mRNAs in rat liver by in situ hybridization: usefulness of paraffin embedding and comparison of various fixation procedures. J His-tochem Cytochem 1987; 35: 453459.
  • 19
    McSween RNM, Anthony PP, Scheuer PJ. Pathology of the liver. 2nd ed. Edinburgh: Churchill Livingstone, 1987: 342360.
  • 20
    Van Noorden CJF, Frederiks WM. Enzyme histochemistry. A laboratory manual of current methods. Oxford: Oxford Science Publications, 1992: 7279.
  • 21
    Braakman I, Keij J, Meijer DKF, Groothuis GMM. Separation of periportal and perivenous hepatocytes by fluorescence-activated cell-sorting: confirmation with colloidal gold as an exogenous marker. Hepatology 1991; 13: 7382.
  • 22
    Chiquoine AD. The distribution of glucose-6-phosphatase in the liver and in the kidney of the mouse. J Histochem Cytochem 1953; 1: 429435.
  • 23
    Christa L, Simon MT, Flinois J-P, Gebhardt R, Brechot C, Lasserre C. Over expression of glutamine synthetase in human primary liver cancer. Gastroenterology 1994; 106: 13121320.
  • 24
    Graham RC Jr, Karnovsky MJ. The early stages of absorption of injected horseradish peroxidase in the proximal tubules of mouse kidney: ultra-structural cytochemistry by a new technique. J Histochem Cytochem 1966; 14: 291302.
  • 25
    Fiorentino M, Grigioni WF, Baccarini P, D'Errico A, De Mitri MS, Pisi E, Mancini A-M. Different in situ expression of insulin-like growth factor type II in hepatocellular carcinoma. An in situ hybridization and immuno-histochemical study. Diagn Mol Pathol 1994; 3: 5965.
  • 26
    Shank RE, Morrison G, Chen HC, Karl I, Schwartz R. Cell heterogeneity within the hepatic lobule (quantitative histochemistry). J Histochem Cytochem 1959; 7: 236239.
  • 27
    Wachstein M. Enzymatic histochemistry of the liver. Gastroenterology 1959; 37: 11441153.
  • 28
    Morrison GR, Shank RE. The quantitative histochemistry of the pseudolobule in human subacute hepatic necrosis. J Lab Clin Med 1966; 67: 3342.
  • 29
    Schmidt E, Schmidt FW. Enzyme activities in human liver. Enzym Biol Clin 1970; 11: 67129.
  • 30
    Aoe H, Tanaka A, Kosaka K. Histochemical demonstration of human liver hexokinase using nitro-blue tetrazolium. Acta Histochem Cytochem 1975; 8: 17.
  • 31
    Cresteil T, Beaune P, Kremers P, Celier C, Guengerich FP, Leroux J-P. Immunoquantification of epoxide hydrolase and cytochrome P-450 isozymes in fetal and adult human liver microsomes. Eur J Biochem 1985; 151: 345350.
  • 32
    Sokal EM, Trivedi P, Cheeseman P, Portmann B, Mowat AP. The application of quantitative cytochemistry to study the acinar distribution of enzymatic activities in human liver biopsy samples. J Hepatol 1989; 9: 4248.
  • 33
    Wimmer M, Luttringer C, Colombi M. Enzyme activity patterns of phosphoenolpyruvate carboxykinase, pyruvatekinase, glucose-6-phosphate-dehydrogenase and malic enzyme in human liver. Histochemistry 1990; 93: 409415.
  • 34
    Chamlian A, Benkoel L, Bongrand P, Gulian J-M, Brisse J. Quantitative histochemical study of glucose-6-phosphatase in periportal and perivenous human hepatocytes. Cell Mol Biol 1991; 37: 183190.
  • 35
    Maly IP, Sasse D. Intraacinar profiles of alcohol dehydrogenase and aldehyde dehydrogenase activities in human liver. Gastroenterology 1991; 101: 17161723.
  • 36
    Sokal EM, Collette E, Buts J-P. Continuous increase of alcohol dehydrogenase activity along the liver plate in normal and cirrhotic human livers. Hepatology 1993; 17: 202205.
  • 37
    Multhaupt H, Fritz P, Schumacher K. Immunohistochemical localization of arginase in human liver using monoclonal antibodies against human liver arginase. Histochemistry 1987; 87: 465470.
  • 38
    Gebhardt R, Schmid H, Fitzke H. Immunohistochemical localization of glutamine synthetase in human liver. Experientia 1989; 45: 137139.
  • 39
    Moorman AFM, Vermeulen JLM, Charles R, Lamers WH. Localization of ammonia-metabolizing enzymes in human liver: ontogenesis of heterogeneity. Hepatology 1989; 9: 367372.
  • 40
    Matsuno T, Goto I. Glutaminase and glutamine synthetase activities in human cirrhotic liver and hepatocellular carcinoma. Cancer Res 1992; 52: 11921194.
  • 41
    Murray GI, Barnes TS, Sewell HF, Ewen SWB, Melvin WT, Show PM, Fowler J. et al. Cytochrome P-450 localization in normal human adult and foetal liver by immunohistochemistry using a monoclonal antibody against human cytochrome P-450. Histochemistry 1987; 19: 537545.
  • 42
    Murray GI, Taylor A, Barnes TS, Weaver R, Ewen SWB, Melvin WT, Burke MD. et al. The distribution of different forms of cytochrome P-450 in human liver. Biochem Soc Trans 1990; 1: 1202.
  • 43
    McKinnon RA, Hall PDLM, Quattrocchi LC, Tukey RH, McManus ME. Localization of CYP1A1 and CYP1A2 messenger RNA in normal human liver and in hepatocellular carcinoma by in situ hybridization. Hepatology 1991; 14: 848856.
  • 44
    Tsutsumi M, Lasker JM, Shimizu M, Rosman AS, Lieber CS. The intralobular distribution of ethanol-inducible P450IIE1 in rat and human liver. Hepatology 1989; 10: 437446.
  • 45
    Takahashi T, Lasker JM, Rosman AS, Lieber CS. Induction of cytochrome P-4502E1 in the human liver by ethanol is caused by a corresponding increase in encoding messenger RNA. Hepatology 1993; 17: 236245.
  • 46
    Kuo CF, Darnell JE Jr. Evidence that the interaction of hepatocytes with collecting (hepatic) veins trigger position-specific transcription of glutamine synthetase and ornithine aminotransferase genes in the mouse liver. Mol Cell Biol 1991; 11: 60506058.
  • 47
    Wagenaar GTM, Moorman AFM, Chamuleau RAFM, Deutz NEP, De Gier C, De Boer PAJ, Verbeek FJ. et al. Vascular branching pattern and zonation of gene expression in the mammalian liver. Anat Rec 1994; 239: 441452.
  • 48
    Poliard A, Bernuau D, Tournier I, Legrés LG, Schoevaert D, Feldmann G, Sala-Trépat JM. et al. Cellular analysis by in situ hybridization and immunoperoxidase of α-fetoprotein and albumin gene expression during the perinatal period. J Cell Biol 1986; 103: 777786.
  • 49
    Moorman AFB, De Boer PAJ, Das AT, Evans D, Charles R, Lamers WH. Expression patterns of mRNAs for α-fetoprotein and albumin in the developing rat: the ontogenesis of hepatocyte heterogeneity. Histochem J 1990; 22: 653660.
  • 50
    Racine L, Scoazec J-Y, Moreau A, Chassagne P, Bernuau D, Feldmann G. Distribution of albumin, α1-inhibitor 3 and their respective mRNAs in periportal and perivenous rat hepatocytes isolated by the digitonin-collagenase technique. Biochem J 1995; 305: 263268.
  • 51
    Hoffmann GE, Andres H, Weiss L, Kreisel C, Sander R. Lipogenesis in man: properties and organ distribution of ATP citrate (pro-SS-)-lyase. Biochim Biophys Acta 1980; 620: 151158.
  • 52
    Matsumoto Y, Bishop AE, McCaughan GW. Altered zonal expression of the CD26 antigen (dipeptidyl peptidase IV) in human cirrhotic liver. Hepatology 1992; 15: 10481053.
  • 53
    Teutsch HF, Altemus J, Gerlach-Arbeiter S, Kyander-Teutsch TL. Distribution of 3-hydroxybutyrate dehydrogenase in primary lobules of rat liver. J Histochem Cytochem 1992; 40: 213219.
  • 54
    Sokal EM, Collette E, Buts JP. Persistence of a liver metabolic zonation in extra-hepatic biliary atresia cirrhotic livers. Pediatr Res 1991; 30: 286289.
  • 55
    Lamers WH, Been W, Charles R, Moorman AFM. Hepatocytes transplanted into the spleen preferentially express carbamoylphosphate synthetase rather than glutamine synthetase. Hepatology 1990; 12: 701709.
  • 56
    Maganto P, Traber PG, Rusnell C, Dobbins WO III, Keren D, Gumucio JJ. Long-term maintenance of the adult pattern of liver-specific expression for P-450b, P-450e, albumin and α-fetoprotein genes in intrasplenically transplanted hepatocytes. Hepatology 1990; 11: 585593.
  • 57
    Chen L, Davis GJ, Crabb DW, Lumeng L. Intrasplenic transplantation of isolated periportal and perivenous hepatocytes as a long-term system for study of liver-specific gene expression. Hepatology 1994; 19: 989998.
  • 58
    Racine L, Scoazec J-Y, Verthier N, Bernuau D, Feldmann G. Morphological aspects of hepatocytes transplanted into the spleen. Transplantology 1994; 5: 129135.
  • 59
    Gebhardt R, Jirtle R, Moorman AFM, Lamers WH, Michalopoulos G. Induction of glutamine synthetase and transient co-expression with carbamoylphosphate synthetase in hepatocytes transplanted into fat pads of syngeneic hosts. Histochemistry 1989; 92: 337342.
  • 60
    Dinges HP, Zatloukal K, Denk H, Smolle J, Mair S. Alcoholic liver disease. Parenchyma to stroma relationship in fibrosis and cirrhosis as revealed by three-dimensional reconstruction and immunohistochemistry. Am J Pathol 1992; 141: 6983.
  • 61
    Courtoy PJ, Feldmann G, Rogier E, Moguilevsky N. Plasma protein synthesis in experimental cirrhosis. Morphologic demonstration and functional correlations. Lab Invest 1981; 45: 6776.
  • 62
    Wood AJ, Villeneuve J-P, Branch RA, Rogers LW, Shand DG. Intact hepatocyte theory of impaired drug metabolism in experimental cirrhosis in the rat. Gastroenterology 1979; 76: 13581362.