• 1
    Hollinger R, Ticehurst J. Hepatitis A virus. In: FieldsB, KnipeD, HowleyP. et al., eds. Fields virology. Philadelphia: Lippincott-Raven, 1996, 1: 735782.
  • 2
    Ganem D. Hepadnaviridae and their replication. In: FieldsB, KnipeD, HowleyP, et al., eds. Fields virology. Philadelphia: Lippincott-Raven, 1996, 1: 27012737.
  • 3
    Feinstone SM, Mihalik KB, Kamimura T, Alter HJ, London WT, Purcell RH. Inactivation of hepatitis B virus and non-A, non-B hepatitis by chloroform. Infect Immun 1983; 41: 816821.
  • 4
    He LF, Ailing D, Popkin T, Shapiro M, Alter HJ, Purcell RH. Determining the size of non-A, non-B hepatitis virus by filtration. J Infect Dis 1987; 156: 636640.
  • 5
    Grakoui A, McCourt DW, Wychowski C, Feinstone SM, Rice CM. A second hepatitis C virus-encoded proteinase. Proc Natl Acad Sci U S A 1993; 90: 1058310587.
  • 6
    Hijikata M, Mizushima H, Akagi T. et al. Two distinct proteinase activities required for the processing of a putative nonstructural precursor protein of hepatitis C virus. J Virol 1993; 67: 46654675.
  • 7
    Grakoui A, McCourt DW, Wychowski C, Feinstone SM, Rice CM. Characterization of the hepatitis C virus-encoded serine proteinase: determination of proteinase-dependent polyprotein cleavage sites. J Virol 1993; 67: 28322843.
  • 8
    Eckart MR, Selby M, Masiarz F. et al. The hepatitis C virus encodes a serine protease involved in processing of the putative nonstructural proteins from the viral polyprotein precursor. Biochem Biophys Res Commun 1993; 192: 399406.
  • 9
    Bartenschlager R, Ahlborn LL, Mous J, Jacobsen H. Nonstructural protein 3 of the hepatitis C virus encodes a serine-type proteinase required for cleavage at the NS3/4 and NS4/5 junctions. J Virol 1993; 67: 38353844.
  • 10
    Tanji Y, Hijikata M, Satoh S, Kaneko T, Shimotohno K. Hepatitis C virusencoded nonstructural protein NS4A has versatile functions in viral protein processing. J Virol 1995; 69: 15751581.
  • 11
    Bartenschlager R, Lohmann V, Wilkinson T, Koch JO. Complex formation between the NS3 serine-type proteinase of the hepatitis C virus and NS4A and its importance for polyprotein maturation. J Virol 1995; 69: 75197528.
  • 12
    Santolini E, Pacini L, Fipaldini C, Migliaccio G, Monica N. TheNS2 protein of hepatitis C virus is a transmembrane polypeptide. J Virol 1995; 69: 74617471.
  • 13
    Matsuura Y, Suzuki T, Suzuki R. et al. Processing of El and E2 glycoproteins of hepatitis C virus expressed in mammalian and insect cells. Virology 1994; 205: 141150.
  • 14
    Selby MJ, Glazer E, Masiarz F, Houghton M. Complex processing and protein: protein interactions in the E 2: NS2 region of HCV. Virology 1994; 204: 114122.
  • 15
    Takahashi K, Kishimoto S, Yoshizawa H, Okamoto H, Yoshikawa A, Mi-shiro S. P26 protein and 33 nm particle associated with nucleocapsid of hepatitis C virus recovered from the circulation of infected hosts. Virology 1992; 191: 431434.
  • 16
    Kaito M, Watanabe S, Tsukiyama KK. et al. Hepatitis C virus particle detected by immunoelectron microscopic study. J Gen Virol 1994: 17551760.
  • 17
    Thomssen R, Bonk S, Thiele A. Density heterogeneities of hepatitis C virus in human sera due to the binding of beta-lipoproteins and immunoglobulins. Med Microbiol Immunol (Berl) 1993; 182: 329334.
  • 18
    Shimizu Y, Feinstone S, Kohara M, Purcell R, Yoshikura H. Hepatitis C virus: detection of intracellular virus particles by electron microscopy. Hepatology 1996; 23: 205209.
  • 19
    Tanaka T, Kato N, Cho MJ, Shimotohno K. A novel sequence found at the 3′-terminus of hepatitis C virus genome. Biochem Biophys Res Commun 1995; 215: 744749.
  • 20
    Kolyhalov A, Feinstone S, Rice C. Identification of a highly conserved sequence element at the 3′-terminus of hepatitis C virus genome RNA. J Virol 1996; 70: 33633371.