SEARCH

SEARCH BY CITATION

References

  • 1
    Wiesner RH, Ludwig J, Lindor KD, Jorgensen RA, Baldus WP, Homburger HA, Dickson ER. A controlled trial of cyclosporin in the treatment of primary biliary cirrhosis. N Engl J Med 1990; 322: 14191424.
  • 2
    Lombard M, Portmann B, Neuberger J, Williams R, Tygstrup N, Ranek L, Ring-Larsen H, et al. Cyclosporin A treatment in primary biliary cirrhosis: results of a long-term placebo controlled trial. Gastroenterology 1993; 104: 519526.
  • 3
    Hoofnagle JH, Davis GL, Schafer DF, Peters M, Avigan MI, Pappas SC, Hanson RG, et al. Randomized trial of chlorambucil for primary biliary cirrhosis. Gastroenterology 1986; 91: 13271334.
  • 4
    Bassendine MF, Macklon AF, Mulcahy R, James OFW. Controlled trial of high and low dose D-penicillamine in primary biliary cirrhosis: results at three years [Abstract]. Gut 1982; 23: 909.
  • 5
    Bodenheimer HC, Schaffner F, Sternlieb I, Klion FM, Vernace S, Pezzullo J. A prospective clinical trial of D-penicillamine in the treatment of primary biliary cirrhosis. Hepatology 1985; 5: 11391142.
  • 6
    Dickson ER, Fleming TR, Wiesner RH, Baldus WP, Fleming CR, Ludwig J, MacCall JT. Trial of penicillamine in advanced primary biliary cirrhosis. N Engl J Med 1985; 312: 10111015.
  • 7
    Epstein O, Jain S, Lee RG, Cook DG, Boss AM, Jain S, Scheuer PJ, et al. D-penicillamine treatment improves survival in primary biliary cirrhosis. Lancet 1981; 1: 12751277.
  • 8
    Matloff DS, Alpert E, Resnick RH, Kaplan MM. A prospective trial of D-penicillamine in primary biliary cirrhosis. N Engl J Med 1982; 306: 319326.
  • 9
    Neuberger J, Christensen E, Portmann B. Double blind controlled trial of D-penicillamine in patients with primary biliary cirrhosis. Gut 1985; 26: 114119.
  • 10
    Taal BG, Schalm SW, Ten Kate FWJ, Van Berge Henegouwen GP, Brandt KH. Low therapeutic value of D-penicillamine in a short-term prospective trial in primary biliary cirrhosis. Liver 1983; 3: 345352.
  • 11
    Triger DR, Manifold IH, Cloke P, Underwood JCE. D-penicillamine in primary biliary cirrhosis: two year results of a single centre, double-blind controlled trial [Abstract]. Gut 1980; 21: 919920.
  • 12
    Christensen E, Neuberger J, Crowe JP, Altman DG, Popper H, Portmann B, Doniach D, et al. Beneficial effect of azathioprine and prediction of prognosis in primary biliary cirrhosis. Final results of an international trial. Gastroenterology 1985; 89: 10841091.
  • 13
    Heathcote J, Ross A, Sherlock S. A prospective controlled trial of azathioprine in primary biliary cirrhosis. Gastroenterology 1976; 70: 656660.
  • 14
    Crowe JP, Christensen E, Smith M, Cochrane M, Ranek L, Watkinson G, Doniach D, et al. Azathioprine in primary biliary cirrhosis: a preliminary report of an international trial. Gastroenterology 1980; 78: 10051010.
  • 15
    Mitchison HC, Bassendine MF, Malcolm AJ, Watson AJ, Record CO, James OFW. A pilot, double-blind, controlled 1-year trial of prednisolone treatment in primary biliary cirrhosis: hepatic improvement but greater bone loss. Hepatology 1989; 10: 420429.
  • 16
    Mitchison HC, Palmer JM, Bassendine MF, Watson AJ, Record CO, James OFW. A controlled trial of prednisolone treatment in primary biliary cirrhosis. Three-year results. J Hepatol 1992; 15: 336344.
  • 17
    Poupon RE, Balkau B, Eschwège E, Poupon R, The UDCA-PBC Study Group. A multicenter, controlled trial of ursodiol for the treatment of primary biliary cirrhosis. N Engl J Med 1991; 324: 15481554.
  • 18
    Lindor KD, Dickson ER, Baldus WP, Jorgensen RA, Ludwig J, Murtaugh P, Harrison JM, et al. Ursodeoxycholic acid in the treatment of primary biliary cirrhosis. Gastroenterology 1994; 106: 12841290.
  • 19
    Heathcote EJ, Cauch-Dudek K, Walker V, Bailey RJ, Blendis LM, Ghent CN, Michieletti P, et al. The Canadian multicenter double-blind randomized controlled trial of Ursodeoxycholic acid in primary biliary cirrhosis. Hepatology 1994; 19: 11491156.
  • 20
    Poupon RE, Poupon R, Balkau B, The UDCA-PBC Study Group. Ursodiol for the long-term treatment of primary biliary cirrhosis. N Engl J Med 1994; 330: 13421347.
  • 21
    Heathcote EJ, Lindor KD, Poupon R, Cauch-Dudek K, Dickson ER, Trout R, Poupon RE. Combined analysis of French, American and Canadian randomized trials of Ursodeoxycholic acid therapy in primary biliary cirrhosis [Abstract]. Gastroenterology 1995; 108: 1086.
  • 22
    Kaplan MM, Ailing DW, Zimmerman HJ, Wolfe HJ, Sepersky RA, Hirsch GS, Elta GH, et al. A prospective trial of colchicine for primary biliary cirrhosis. N Engl J Med 1986; 315: 14481454.
  • 23
    Warnes TW, Smith A, Lee FI, Haboubi NY, Johnson PJ, Hunt L. A controlled trial of colchicine in primary biliary cirrhosis. Trial design and preliminary report. J Hepatol 1987; 5: 17.
  • 24
    Bodenheimer HC, Schaffner F, Pezzullo J. Evaluation of colchicine therapy in primary biliary cirrhosis. Gastroenterology 1988; 95: 124129.
  • 25
    Labbé D, Gerhardt M, Myara A, Vercambre C, Trivin F. High-performance liquid chromatographic determination of tauro- and glyco-conjugated bile acids in human serum. J Chromatogr 1989; 1989: 275284.
  • 26
    Gibaldi M, Perrier D. In: Pharmacokinetics. Ed 2. New York: Dekker, 1982: 433444.
  • 27
    Rodhe H, Vargas L, Hahn E, Kalbfleisch H, Bruguera M, Timpl R. Radio-immunoassay for type III procollagen peptide and its application to human diease. Eur J Clin Invest 1979; 9: 451459.
  • 28
    Brandt R, Hedlöf E, Asman I, Bucht A, Tengblad A. A convenient radiomet-ric assay for hyaluronan. Acta Otolaryngol 1987; 442: 3135.
  • 29
    Dickson ER, Grambsch PM, Fleming TR, Fisher LD, Langworthy A. Prognosis in primary biliary cirrhosis: model for decision making. Hepatology 1989; 10: 17.
  • 30
    Scheuer PJ. Primary biliary cirrhosis. Proc R Soc Med 1967; 60: 12571260.
  • 31
    Mehta CR, Patel NR, Tsiatis AA. Exact significance testing to establish treatment equivalence with ordered categorical data. Biometrics 1984; 40: 819825.
  • 32
    Risteli J, Risteli L. Analysing connective tissue metabolites in human serum. Biochemical, physiological and methodological aspects. J Hepatol 1995; 22(suppl 2): 7781.
  • 33
    Vaubourdolle M, Gufflet V, Chazouillères O, Giboudeau J, Poupon R. Indo-cyanine green-sulfobromophthalein pharmacokinetics for diagnosing primary biliary cirrhosis and assessing histological severity. Clin Chem 1991; 37: 16881690.
  • 34
    Raedsch R, Stiehl A, Walker S, Theilman L, Kommerell B. Effects of Ursodeoxycholic acid and Ursodeoxycholic acid plus colchicine in primary biliary cirrhosis: a double-blind pilot study. In: PaumgartnerG, StiehlA, GerokW, eds. Bile acids as therapeutic agents. From basic science to clinical practice. Dordrecht: Kluwer Academic, 1991: 301304.
  • 35
    Almasio P, Provenzano G, Battezzati PM, Podda M, Todros L, Rosina F, Saccocio G, et al. The Italian multi-centre randomized controlled trial of Ursodeoxycholic acid vs Ursodeoxycholic acid plus colchicine in symptomatic primary biliary cirrhosis [Abstract]. Hepatology 1994; 20: 267.
  • 36
    Vuoristo M, Färkkilä M, Karvonen A-L, Leino R, Lehtola J, Mäkinen J, Mattila J, et al. A placebo-controlled trial of primary biliary cirrhosis treatment with colchicine and Ursodeoxycholic acid. Gastroenterology 1995; 108: 14701478.
  • 37
    Hallbrucker C, Lang F, Gerok W, Haüssinger D. Cell swelling increases bile flow and taurocholate excretion into bile in isolated perfused rat liver. Biochem J 1992; 281: 593595.
  • 38
    Sherlock S. Therapeutic trials in primary biliary cirrhosis. Q J Med 1994; 87: 701703.
  • 39
    Leighton J, Bay M, Maldonado A, Johnson R, Schenker S, Speeg K. The effect of liver dysfunction on colchicine pharmacokinetics in the rat. Hepatology 1990; 11: 210215.
  • 40
    Leighton JA, Bay MK, Maldonado AL, Schenker S, Speeg KV. Colchicine clearance is impaired in alcoholic cirrhosis. Hepatology 1991; 14: 10131015.