• 1
    Verkade HJ, Vonk RJ, Kuipers F. New insights into the mechanism of bile acid-induced biliary lipid secretion. Hepatology 1995; 2: 11741189.
  • 2
    Rigotti A, Marzolo MP, Neri F. Lipid transport from the hepatocyte into the bile. Curr Top Membranes 1994; 2: 579615.
  • 3
    Coleman R, Iqhal S, Godfrey P, Billington D. Composition of several mammalian biles and their membrane damaging properties. Biochem J 1979; 2: 201208.
  • 4
    Rosario J, Sutherland E, Zaccaro L, Simon F. Ethinyl-estradiol administration selectively alters liver sinusoidal membrane lipid fluidity and protein composition. Biochemistry 1988; 2: 39293946.
  • 5
    Devaux PF. Static and dynamic lipid asymmetry in cell membranes. Biochemistry 1991; 30: 11631173.
  • 6
    Zachowski A. Phospholipids in animal eukaryotic membranes: transverse asymmetry and movement. Biochem J 1993; 294: 114.
  • 7
    Op den Kamp JAF. Lipid asymmetry in membranes. Biochim Biophys Acta 1979; 2: 4771.
  • 8
    Calvez JY, Zachowski A, Herrmann A, Morrot G, Devaux PF. Asymmetric distribution of phospholipids in spectrin-poor erythrocyte vesicles. Biochemistry 1988; 2: 56665670.
  • 9
    Seigneuret M, Devaux PF. ATP-dependent asymmetric distribution of spin-labelled phospholipids in the erythrocyte membranes: relation to shape changes. Proc Natl Acad Sci U S A 1984; 23: 37513755.
  • 10
    Zachowski A, Herrmann A, Paraf A, Devaux PF. Phospholipid outsideinside translocation in lymphocyte plasma membranes is a protein-mediated phenomenon. Biochim Biophys Acta 1987; 897: 197200.
  • 11
    Sune A, Bette-Bobillo P, Bienveniie A, Fellmann P, Devaux PF. Selective outside-inside translocation of aminophospholipids in human platelets. Biochemistry 1987; 2: 29722978.
  • 12
    Müller K, Pomorski T, Miiller P, Zachowski A, Herrmann A. Protein-dependent translocation of aminophospholipids in the plasma membrane of ram sperm cells. Biochemistry 1994; 2: 99689974.
  • 13
    Morrot G, Herve P, Zachowski A, Fellmann P, Devaux PF. Aminophospholipid translocase of human erythrocytes: phospholipid substrate specifity and effect of cholesterol. Biochemistry 1989; 28: 34563462.
  • 14
    Auland ME, Roufogalis BD, Devaux PF, Zachowski A. Reconstitution of ATP-dependent aminophospholipid translocation in proteoliposomes. Proc Natl Acad Sci U S A 1994; 2: 1093810942.
  • 15
    Schroit AJ, Bloy C, Connor J, Cartron J. Involvement of RH blood group polypeptides in the maintenance of aminophospholipid asymmetry. Biochemistry 1990; 2: 1030310306.
  • 16
    Heinrich R, Brumen M, Jaeger A, Müller P, Herrmann A. Modelling of phospholipid translocation in the erythrocyte membrane. A combined kinetic and thermodynamic approach. J Theor Biol 1996; in press.
  • 17
    Ihrke G, Neufeld EB, Meads T, Shanks MR, Cassio D, Laurent M, Schroer TA, et al. WIF-B cells: an in vitro model for studies of hepatocyte polarity. J Cell Biol 1993; 123: 17611775.
  • 18
    Aden DP, Fogel A, Damjanov I, Plotkin S, Knowles BB. Controlled synthesis of HBsAg in a differentiated human liver carcinoma-derived cell line. Nature 1979; 282: 615616.
  • 19
    Schwartz AL, Rup D. Biosynthesis of the human asialoglycoprotein receptor. J Biol Chem 1983; 258: 1124911255.
  • 20
    Koumanov KS, Momchilova-Pankova AB, Wang SR, Infante R. Membrane phospholipid composition, fluidity and phospholipase A2 activity of the human hepatoma cell line HepG2. Int J Biochem 1990; 2: 14531455.
  • 21
    Tilley L, Cribier S, Roelofsen B, Op den Kamp JAF, Van Deenen LLM. ATP-dependent translocation of aminophospholipids across the human erythrocyte membrane. FEBS Lett 1986; 2: 2127.
  • 22
    Rouser G, Fleisher S, Yamamoto A. Quantitative analysis of phospholipids by thin-layer chromatography and phosphorus analysis of spots. Lipids 1966; 2: 494496.
  • 23
    Bligh EG, Dyer WJ. A rapid method of total lipid extraction and purification. Can J Biochem Physiol 1959; 37: 911917.
  • 24
    Seigneuret M, Zachowski A, Herrmann A, Devaux PF. Asymmetric lipid fluidity in human erythrocyte membrane: new spin label evidence. Biochemistry 1984; 23: 42714275.
  • 25
    Sleight RG, Pagano RE. Transbilayer movement of a fluorescent phospha-tidylethanolamine analogue across the plasma membrane of cultured mammalian cells. J Biol Chem 1985; 260: 11461154.
  • 26
    Pomorski T, Müller P, Zimmermann B, Burger K, Devaux PF, Herrmann A. Transmembrane movement of fluorescent and spin-labelled phospholipids in the plasma membrane of human fibroblasts. A quantitative approach. J Cell Sci 1996; 2: 687698.
  • 27
    Oka JA, Weigel PH. The pathways for fluid phase and receptor mediated endocytosis in rat hepatocytes are different but thermodynamically equivalent. Biochem Biophys Res Commun 1989; 2: 488494.
  • 28
    Clarke BL, Weigel PH. Recycling of the asialoglycoprotein receptor in isolated rat hepatocytes. J Biol Chem 1985; 260: 128133.
  • 29
    Julien M, Tournier JF, Tocanne JF. Differences in the transbilayer and lateral motions of fluorescent analogs of phosphatidylcholine and phospha-tidylethanolamine in the apical plasma membrane of bovine aortic endothelial cells. Exp Cell Res 1993; 2: 387397.
  • 30
    Julien M, Tournier JF, Tocanne JF. Basic fibroblast growth factor modulates the aminophospholipid translocase activity in the plasma membrane of bovine aortic endothelial cells. Eur J Biochem 1995; 2: 287297.
  • 31
    Menon AK. Flippases. Trends Cell Biol 1995; 2: 355360.
  • 32
    Smit JJM, Schinkel AH, Ou de Elferink RPJ, Groen AK, Wagenaar E, Van Deetmer L. Mol CAAM, et al. Homozygous disruption of the murine mdr2 P-glycoprotein gene leads to a complete absence of phospholipid from the bile and to liver disease. Cell 1993; 2: 451462.
  • 33
    Smith AJ, Timmermans-Hereijgers JLPM, Roelofsen B, Wirtz KWA, Van Blitterswijk WJ, Smit JJM, Schinkel AH. et al. The human mdr3 P-glycoprotein promotes translocation of phosphatidylcholine through the plasma membrane of fibroblasts of transgenic mice. FEBS Lett 1994; 2: 263266.
  • 34
    Ruetz S, Gros P. Phosphatidylcholine translocase: a physiological role of the mdr2 gene. Cell 1994; 77: 10711081.