SEARCH

SEARCH BY CITATION

References

  • 1
    Beasley RP, Hwang LY, Lin CC, Chien CS. Hepatocellular carcinoma and hepatitis B virus. Lancet 1981; 2: 11291133.
  • 2
    Chisari FV, Klopchin K, Moriyama T, Pasquinelli C, Dunsford HA, Sell S, Pinkert CA, et al. Molecular pathogenesis of hepatocellular carcinoma in hepatitis B virus transgenic mice. Cell 1989; 59: 11451156.
  • 3
    Hino O, Tabata S, Hotta Y. Evidence for increased in vitro recombination with insertion of human hepatitis B virus DNA. Proc Natl Acad Sci USA 1991; 83: 83388343.
  • 4
    Dejean A, Bougueleret L, Grzeschik KH, Tiollais P. Hepatitis B virus DNA integration in a sequence homologous to v–erb A and steroid receptor genes in a hepatocellular carcinoma. Nature 1986; 322: 7072.
  • 5
    Wang J, Chenivesse X, Henglein B, Brechot C. Hepatitis B virus integration in a cyclin A gene in a human hepatocellular carcinoma. Nature 1990; 343: 555557.
  • 6
    Popper H, Roth L, Purcell RH, Tennant BC, Gerin JL. Hepatocarcinogeni-city of the woodchuck hepatitis virus. Proc Natl Acad Sci USA 1987; 84: 866870.
  • 7
    Hsu T-Y, Möröy T, Etiemble J, Louise A, Trépo C, Tiollais P, Buendia MA. Activation of c-myc by woodchuck hepatitis virus insertion in hepatocellular carcinoma. Cell 1988; 55: 627635.
  • 8
    Fourel G, Trepo C, Bougueleret L, Henglein B, Ponzetto A, Tiollais P, Buendia MA. Frequent activation of N-myc genes by hepadnavirus insertion in woodchuck liver tumours. Nature 1990; 347: 294298.
  • 9
    Fourel G, Couturier J, Wei Y, Apiou F, Tiollais P, Buendia MA. Evidence for long-range oncogene activation by hepadnavirus insertion. EMBO J 1994; 13: 25262534.
  • 10
    Wei Y, Fourel G, Ponzetto A, Silvestro M, Tiollais P, Buendia M-A. Hepadnavirus integration: mechanisms of activation of the N-myc2 retrotranspo-son in woodchuck liver tumors. J Virol 1992; 66: 52655276.
  • 11
    Sandgren EP, Quaife CJ, Pinkert CA, Palmiter RD, Brinster RL. Oncogene-induced liver neoplasia in transgenic mice. Oncogene 1989; 4: 715724.
  • 12
    Sepulveda AR, Finegold MJ, Smith B, Slagle BL, DeMayo JL, Shen R-F, Woo SLC, et al. Development of a transgenic mouse system for the analysis of stages in liver carcinogenesis using tissue-specific expression of SV40 large T-antigen controlled by regulatory elements of the human a-l-anti-trypsin gene. Cancer Res 1989; 49: 61086117.
  • 13
    Kim C-M, Koike K, Saito I, Miyamura T, Jay G. HBx gene of hepatitis B virus induces liver cancer in transgenic mice. Nature 1991; 351: 317320.
  • 14
    Cartier N, Miquerol L, Tulliez M, Lepetit N, Levrat F, Grimbert G, Briand P, et al. Diet-dependent carcinogenesis of pancreatic islets and liver in transgenic mice expressing oncogenes under the control of the L-type py-ruvate kinase gene promoter. Oncogene 1992; 7: 14131422.
  • 15
    Murakami H, Sanderson ND, Nagy P, Marino PA, Merlino G, Thorgeirsson SS. Transgenic mouse model for synergistic effects of nuclear oncogenes and growth factors in tumorigenesis: interaction of c-myc and transforming growth factor α in hepatic oncogenesis. Cancer Res 1993; 53: 17191723.
  • 16
    Geller SA, Nichols WS, Kim S, Tolmachoff T, Lee S, Dycaico MJ, Felts K, et al. Hepatocarcinogenesis is the sequel to hepatitis in Z#2 α1-antitrypsin transgenic mice: histopathological and DNA ploidy studies. Hepatology 1994; 19: 389397.
  • 17
    Huang S-N, Chisari FV. Strong, sustained hepatocellular proliferation precedes hepatocarcinogenesis in hepatitis B surface antigen transgenic mice. Hepatology 1995; 21: 620626.
  • 18
    Hagen TM, Huang S, Curnutte J, Fowler P, Martinez V, Wehr CM, Ames BN, et al. Extensive oxidative damage in hepatocytes of transgenic mice with chronic active hepatitis destined to develop hepatocellular carcinoma. Proc Natl Acad Sci U S A 1994; 91: 1280812812.
  • 19
    Jhappan C, Stable C, Harkins RN, Fausto N, Smith GH, Merlino GT. TGFα over expression in transgenic mice induces liver neoplasia and abnormal development of the mammary gland and pancreas. Cell 1990; 61: 11371146.
  • 20
    Sandgren EP, Luetteke NC, Qiu TH, Palmiter RD, Brinster RL, Lee DC. Transforming growth factor alpha dramatically enhances oncogene-in-duced carcinogenesis in transgenic mouse pancreas and liver. Mol Cell Biol 1993; 13: 320330.
  • 21
    Perraud F, Dalemans W, Genrault JL, Dreyer D, Ali-Hadji D, Favre T, Pavirani A. Characterization of trans-immortalized hepatic cell lines established from transgenic mice. Exp Cell Res 1991; 195: 5965.
  • 22
    Etiemble J, Degott C, Renard CA, Fourel G, Shamoon B, Vivitski-Trepo L, Hsu TY, et al. Liver-specific expression and high oncogenic efficiency of a c-myc transgene activated by woodchuck hepatitis virus insertion. Oncogene 1994; 9: 727737.
  • 23
    Scoazec J-Y, Moreau A, Feldmann G, Bernuau D. Cellular expression of α-fetoprotein gene and its relation to albumin gene expression during rat azo-dye hepatocarcinogenesis. Cancer Res 1989; 49: 17901796.
  • 24
    Dull TJ, Gray A, Hayflick JS, Ullrich A. Insulin-like growth factor II precursor gene organization in relation to insulin gene family. Nature 1984; 310: 777781.
  • 25
    Cox KH, DeLeon DV, Angerer LM, Angerer RC. Detection of mRNAs in sea urchin embryos by in situ hybridization using asymmetric RNA probes. Dev Biol 1984; 101: 485502.
  • 26
    Van Beveren C, Van Straaten F, Curran T, Muller R, Verma IM. Analysis of FB J-MuSV provirus and c-fos (mouse) gene reveals that viral and cellular fos gene products have different carboxy termini. Cell 1983; 32: 12411255.
  • 27
    Miyoshi J, Kagimoto M, Soeda E, Sakaki Y. The human c-Ha-ras2 is a processed pseudogene inactivated by numerous base substitutions. Nucleic Acids Res 1984; 12: 18211828.
  • 28
    Lamph WW, Wansley P, Sassone-Corsi P, Verma I. Induction of protooncogene jun/AP-1 by serum and TPA. Nature 1988; 334: 629631.
  • 29
    Tournier I, Bernuau D, Poliard A, Schoevaert D, Feldmann G. Detection of albumin mRNAs in rat liver by in situ hybridization: usefulness of paraffin embedding and comparison of various fixation procedures. J Histochem Cytochem 1987; 35: 453459.
  • 30
    Roudier-Pujol C, Rochat A, Escoubet B, Eugene E, Barrandon Y, Bonvalet JP, Farman N. Differential expression of epithelial sodium channel subunit mRNAs in rat skin. J Cell Science 1996; 109: 379385.
  • 31
    Church G, Gilbert W. Genomic sequencing. Proc Natl Acad Sci U S A 1984; 81: 19911995.
  • 32
    Gavrieli Y, Sherman Y, Ben-Sasson SA. Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation. J Cell Biol 1992; 119: 493501.
  • 33
    Jungermann K, Katz N. Zonation of metabolism and gene expression in liver. Histochemistry 1995; 103: 8191.
  • 34
    Spencer C, Groudine M. Control of c-myc gene in normal and neoplastic cells. Adv Cancer Res 1991; 56: 148.
  • 35
    Evan GI, Wyllie AH, Gilbert CS, Littlewood TD, Land H, Brooks M, Waters CM, et al. Induction of apoptosis in fibroblasts by c-myc protein. Cell 1992; 69: 119128.
  • 36
    Bissonnette RP, Echeverri F, Mahboudi A, Green DR. Apoptotic cell death induced by c-myc is inhibited by bcl-2. Nature 1992; 359: 552554.
  • 37
    Reisman D, Elkind NB, Roy B, Beamon J, Rotter V. c-Myc trans activates the p53 promoter through a required downstream CACGTG motif. Cell Growth Differ 1993; 4: 5765.
  • 38
    Roy B, Beamon J, Balint E, Reisman D. Transactivation of the human p53 tumor suppressor gene by c-Myc/Max contributes to elevated mutant p53 expression in some tumors. Mol Cell Biol 1994; 14: 78057815.
  • 39
    Hermeking H, Eick D. Mediation of c-Myc-induced apoptosis by p53. Science 1994; 265: 20912093.
  • 40
    Harrington EA, Bennett MR, Fanidi A, Evan GI. c-myc-induced apoptosis in fibroblasts is inhibited by specific cytokines. EMBO J 1994; 13: 32863295.
  • 41
    Ueda K, Ganem D. Apoptosis induced by N-myc expression in hepatocytes, a frequent event in hepadnaviral oncogenesis, is blocked by insulin-like growth factor II. J Virol 1996; in press.
  • 42
    Shiota G, Wang TC, Nakamura T, Schmidt EV. Hepatocyte growth factor in transgenic mice: effects on hepatocyte growth, liver regeneration and gene expression. Hepatology 1994; 19: 962972.
  • 43
    Takagi H, Sharp R, Hammermeister C, Goodrow T, Bradley MO, Fausto N, Merlino G. Molecular and genetic analysis of liver oncogenesis in transforming growth factor α transgenic mice. Cancer Res 1992; 52: 51715177.
  • 44
    Webber EM, Wu JC, Wang L, Merlino G, Fausto N. Over express ion of transforming growth factor-αcauses liver enlargement and increased hepatocyte proliferation in transgenic mice. Am J Pathol 1994; 145: 398408.
  • 45
    Dunsford HA, Sell S, Chisari FV. Hepatocarcinogenesis due to chronic liver cell injury in hepatitis B virus transgenic mice. Cancer Res 1990; 50: 34003407.
  • 46
    Sell S, Hunt JM, Dunsford HA, Chisari FV. Synergy between hepatitis B virus expression and chemical hepatocarcinogens in transgenic mice. Cancer Res 1991; 51: 12781285.
  • 47
    Schirmacher P, Held WA, Yang D, Biempica L, Rogler CE. Selective amplification of periportal transitional cells precedes formation of hepatocellular carcinoma in SV40 large Tag transgenic mice. Am J Pathol 1991; 139: 231241.
  • 48
    Yang D, Alt E, Rogler CE. Coordinate expression of N-myc 2 and insulin-like growth factor II in pre-cancerous altered hepatic foci in woodchuck hepatitis virus carriers. Cancer Res 1993; 53: 20202027.
  • 49
    Hsu TY, Fourel G, Etiemble J, Tiollais P, Buendia MA. Integration of hepatitis virus DNA near c-myc in woodchuck hepatocellular carcinoma. Gastroenterol Jpn 1990; 25: 4348.
  • 50
    Rivkina MB, Cullen JM, Robinson WS, Marion PL. State of the p53 gene in hepatocellular carcinomas of ground squirrels and woodchucks with past and ongoing infection with hepadnaviruses. Cancer Res 1994; 54: 54305437.
  • 51
    Christofori G, Naik P, Hanahan D. A second signal supplied by insulin-like growth factor II in oncogene-induced tumorigenesis. Nature 1994; 369: 414418.
  • 52
    Cariani E, Lasserre C, Seurin D, Hamelin B, Kemeny F, Franco D, Czech MP, et al. Differential expression of insulin-like growth factor II mRNA in human primary liver cancers, benign liver tumors, and liver cirrhosis. Cancer Res 1988; 48: 68446849.
  • 53
    Lamas E, Le Bail B, Housset C, Boucher O, Bréchot C. Localization of insulin-like growth factor-II and hepatitis B virus mRNAs and proteins in human hepatocellular carcinomas. Lab Invest 1991; 64: 98104.