• 1
    Higgins G, Anderson R. Restoration of the liver of the white rat following partial surgical removal. Arch Pathol 1931; 12: 186202.
  • 2
    Leist M, Gantner F, Jilg S, Wendel A. Activation of the 55 kDa TNF receptor is necessary and sufficient for TNF-induced liver failure, hepatocyte apoptosis, and nitrite release. J Immunol 1995; 154: 13071316.
  • 3
    Feingold K, Soued M, Grunfeld C. Tumor necrosis factor stimulates DNA synthesis in the liver of intact rats. Biochem Biophys Res Commun 1988; 153: 576582.
  • 4
    Akerman P, Cote P, Yang S, McClain C, Nelson S, Bagby G, Diehl AM. Antibodies to tumor necrosis factor-alpha inhibit liver regeneration after partial hepatectomy. Am J Physiol 1992; 263: G579G585.
  • 5
    Zhu X, Zellweger R, Zhu X, Ayala A, Chaudry IH. Cytokine gene expression in splenic macrophages and Kupffer cells following haemorrhage. Cytokine 1995; 7: 814.
  • 6
    Nagata Y, Tanaka K, Orita K. Endotoxin-induced liver injury after extended hepatectomy and the role of Kupffer cells in the rat. Surg Today 1994; 24: 441448.
  • 7
    Hardonk MJ, Dijkhuis FW, Hulstaert C, Koudstaal J. Heterogeneity of rat liver and spleen macrophages in gadolinium chloride-induced elimination and repopulation. J Leukoc Biol 1992; 52: 296302.
  • 8
    Rai R, Yang SQ, McClain C, Karp CL, Klein AS, Diehl AM. Kupffer cell depletion by gadolinium chloride enhances liver regeneration after partial hepatectomy in rats. Am J Physiol 1996; 270: G909G918.
  • 9
    Bogdan C, Paik J, Vodovotz Y, Nathan C. Contrasting mechanisms for suppression of macrophage cytokine release by transforming growth factor-beta and interleukin-10. J Biol Chem 1992; 267: 2330123308.
  • 10
    Nicod LP, Habre F, Dayer JM, Boehringer N. Interleukin-10 decreases tumor necrosis factor alpha and beta in alloreactions induced by human lung dendritic cells and macrophages. Am J Respir Cell Mol Biol 1995; 13: 8390.
  • 11
    Bogdan C, Vodovotz Y, Nathan C. Macrophage deactivation by IL-10. J Exp Med 1991; 174: 15491555.
  • 12
    Berg DJ, Kuhn R, Rajewsky K, Muller W, Menon S, Davidson N, Rennick D. Interleukin-10 (IL-10) is a central regulator of the response to LPS in murine models of endotoxic shock and the Schwartzman reaction but not endotoxin tolerance. J Clin Invest 1995; 96: 23392347.
  • 13
    Hoyle GW, Hill RL. Structure of the gene for a carbohydrate-binding receptor unique to rat kupffer cells. J Biol Chem 1991; 266: 18501857.
  • 14
    Eichbaum QG, Iyer R, Raveh DP, Mathieu C, Ezekowitz RA. Restriction of interferon gamma responsiveness and basal expression of the myeloid human Fc gamma Rib gene is mediated by a functional PU.l site and a transcription initiator consensus. J Exp Med 1994; 179: 19851996.
  • 15
    Klein A, Zhadkewich M, Margolick J, Winkelstein J, Bulkley G. Quantitative discrimination of hepatic reticuloendothelial clearance and phagocytic killing. J Leukoc Biol 1994; 55: 248252.
  • 16
    Corti A, Poiesi C, Merli S, Cassani G. Tumor necrosis factor (TNF) alpha quantification by ELISA and bioassay: effects of TNF alpha-soluble TNF receptor (p55) complex dissociation during assay incubations. J Immunol Methods 1994; 177: 191198.
  • 17
    Chomczynski P, Sacchi N. Single step method of RNA isolation by acid guanidine thiocyanate-phenol-chloroform extraction. Anal Biochem 1987; 62: 156161.
  • 18
    Diehl AM, Yin M, Fleckenstein J, Yang SQ, Lin HZ, Brenner DA, Westwick J, et al. Tumor necrosis factor-alpha induces c-jun during the regenerative response to liver injury. Am J Physiol 1994; 267: G552G561.
  • 19
    Karp CL, el-Safi SH, Wynn TA, Satti MM, Kordofani AM, Hashim FA, Hag-Ali M, et al. In vivo cytokine profiles in patients with kala-azar. Marked elevation of both interleukin-10 and interferon-gamma [Comments]. J Clin Invest 1993; 91: 16441648.
  • 20
    Gavreili Y, Sherman Y, Ben-Sasson S. Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation. J Cell Biol 1992; 119: 493501.
  • 21
    Michalopoulos GK. Liver regeneration: molecular mechanisms of growth control. FASEB J 1990; 4: 176187.
  • 22
    Randow F, Syrbe U, Meisel C, Krausch D, Zuckermann H, Platzer C, Volk HD. Mechanism of endotoxin desensitization: involvement of interleukin 10 and transforming growth factor beta. J Exp Med 1995; 181: 18871892.
  • 23
    Hafenrichter DG, Roland CR, Mangino MJ, Flye MW. The Kupffer cell in endotoxin tolerance: mechanisms of protection against lethal endotoxemia. Shock 1994; 2: 251256.
  • 24
    Knolle P, Schlaak J, Uhrig A, Kempf P, Meyer zum Buschenfelde AH, Gerken G. Human Kupffer cells secrete IL-10 in response to lipopolysaccharide (LPS) challenge. J Hepatol 1995; 22: 226229.
  • 25
    Bissell DM, Wang SS, Jarnagin WR, Roll FJ. Cell-specific expression of transforming growth factor-beta in rat liver. Evidence for autocrine regulation of hepatocyte proliferation. J Clin Invest 1995; 96: 447455.
  • 26
    Noiri E, Kuwata S, Nosaka K, Tokunaga K, Juji T, Shibata Y, Kurokawa K. Tumor necrosis factor-alpha mRNA expression in lipopolysaccharide-stimulated rat kidney. Chronological analysis of localization. Am J Pathol 1994; 144: 11591166.
  • 27
    Wagner RD, Czuprynski CJ. Cytokine mRNA expression in livers of mice infected with Listeria monocytogenes. J Leukoc Biol 1993; 53: 525531.
  • 28
    Diehl AM, Rai R. Regulation of liver regeneration by pro-inflammatory cytokines. J Gastroenterol Hepatol 1996; 11: 466470.
  • 29
    Roland CR, Mangino MJ, Duffy BF, Flye MW. Lymphocyte suppression by Kupffer cells prevents portal venous tolerance induction: a study of macrophage function after intravenous gadolinium. Transplantation 1993; 55: 11511158.
  • 30
    Rose ML, Schoonhoven R, Thurman RG. Inactivation of Kupffer cells with methyl palmitate prevents peroxisome proliferator-induced hepatocyte proliferation [Abstract]. Hepatology 1996; 24: A873.