SEARCH

SEARCH BY CITATION

References

  • 1
    Tavoloni N. The intrahepatic biliary epithelium: an area of growing interest in hepatology. Semin Liver Dis 1987; 7: 280292.
  • 2
    Desniet VJ. Cholangiopathies:past, present and future. Semin Liver Dis 1987; 7: 6776.
  • 3
    Strazzabosco M, Okolicsanyi L, Boyer JL. Acid/base transport systems in isolated bile duct epithelial cells. In: GentiliniP, DianzaniMHJ, eds. Experimental and Clinical Hepatology. New York: Elsevier, 1991: 133141.
  • 4
    Tarsetti F, Lenzen R, Salvi R, Schuler E, Dembitzer R, Tavoloni N. Biology and pathobiology of intrahepatic biliary epithelium. In: TavoloniN, BerkPD, eds. Hepatic transport and bile secretion: Physiology and pathophysiology. New York: Raven, 1993: 619634.
  • 5
    Roberts SK, LaRusso NF. Pathobiology of biliary epithelia. Curr Opin Gastroenterol 1994; 10: 526533.
  • 6
    Colombo C, Battezzati PM, Podda M. Hepatobiliary disease in cystic fibro-sis. Semin Liver Dis 1994; 14: 259269.
  • 7
    Lindblad A, Hultcrantz R, Strandvik B. Bile duct destruction and collagen deposition: a prominent ultrastructural feature of the liver in cystic fibro-sis. Hepatology 1992; 16: 372381.
  • 8
    Balistreri WF. The liver - the next frontier in the treatment of patients with cystic fibrosis. In: ReyesHB, LeuschnerU, AriosIM, eds. Pregnancy, Sex Hormones and the Liver. Dordrecht, Boston, London: Kluwer, 1996: 114135.
  • 9
    Alpini G, Lenzi R, Sarkozi L, Tavoloni N. Biliary physiology in rats with bile ductular cell hyperplasia evidence for a secretory function of proliferated bile ductules. J Clin Invest 1988; 81: 569578.
  • 10
    Tietz PS, Alpini G, Pham LD, LaRusso NF. Somatostatin inhibits secretin-induced ductal hypercholeresis and exocytosis by cholangiocytes. Am J Physiol 1995; 269: G110G118.
  • 11
    Strazzabosco M, Mennone A, Boyer JL. Intracellular pHi regulation in isolated rat bile duct epithelial cells. J Clin Invest 1991; 87: 15031512.
  • 12
    Alvaro A, Cho WK, Mennone A, Boyer JL. Effect of secretin on pHi regulation in isolated rat bile duct epithelial cells. J Clin Invest 1993; 92: 13141325.
  • 13
    Joplin R. Isolation and culture of biliary epithelial cells. Gut 1994; 35: 875878.
  • 14
    Joplin R, Hishida T, Tsubouchi H, Daikuhara Y, Ayres R, Neuberger JM, Strain AJ. Human intrahepatic biliary epithelial cells proliferate in vitro in response to human hepatocyte growth factor. J Clin Invest 1992; 90: 12841289.
  • 15
    Boyer JL. Mechanisms of bile secretion and hepatic transport. In: AndreoliTE, HoffmanJF, FanestilDD, SchultzSG, eds. Membrane Transport Processes in Organized Systems. New York, London: Plenum, 1986: 225252.
  • 16
    Strain AJ, Ismail T, Tsoubouchi H, Arakaki N, Hishida T, Kitamura N, Daikuhara Y, et al. Native and recombinant human hepatocyte growth factors are highly potent promoters of DNA synthesis in both human and rat hepatocytes. J Clin Invest 1991; 87: 18531857.
  • 17
    Joplin R, Strain AJ, Neuberger JM. Immuno-isolation and culture of biliary epithelial cells from normal human liver. Vitro Cell Dev Biol 1989; 25: 11891192.
  • 18
    Joplin R, Strain AJ, Neuberger JM. Biliary epithelial cells from the liver of patients with primary biliary cirrhosis: isolation, characterization and short-term culture. J Pathol 1990; 162: 255260.
  • 19
    Momberg F, Moldenhauer G, Hammerling GH. Immunohistochemical study of the surface expression of an Mr 34000 human epithelium specific glycoprotein in normal and malignant tissues. Cancer Res 1987; 47: 28832891.
  • 20
    Knuth A, Gabbert H, Dippold W, Klein O, Sachsse W, Bitter-Suermann D, Prellwitz W, et al. Biliary adenocarcinoma: Characterisation of three new human tumor cell lines. J Hepatol 1985; 1: 579596.
  • 21
    McGill J, Gettys TW, Basavappa S, Fitz JG. Secretin activates Cl channels in bile duct epithelial cells through a cAMP-dependent mechanism. Am J Physiol 1994; 266: G731G736.
  • 22
    Basavappa S, Middleton J, Mangel AW, McGill JM, Cohn JA, Fitz JG. Cl- and K+ transport human biliary cell lines. Gastroenterology 1993; 104: 17961805.
  • 23
    McGill J, Basavappa S, Shimohura SH, Middleton JP, Fitz JG. ATP activates ion permeabilities in biliary epithelial cells. Gastroenterology 1994; 107: 236243.
  • 24
    Strazzabosco M, Poci C, Spirli C, Sartori L, Knuth A, Crepaldi G. Effect of ursodeoxycholic acid on intracellular pH in a bile duct epithelium-like cell line. Hepatology 1994; 19: 145154.
  • 25
    Rink TJ, Tsien RY, Pozzan T. Cytoplasmic pH and free Mg2+ in lymphocytes. J Cell Biol 1982; 95: 189196.
  • 26
    Boyarsky G, Ganz MB, Sterzel RB, Boron WF. pH regulation in single glomerular mesangial cells I. Acid extrusion in absence and presence of HCO3-. Am J Physiol 1988; 255: C844C856.
  • 27
    Thomas JA, Buchsbaum RN, Zimniak A, Racker E. Intracellular pH measurements in Erlich ascites tumor cells utilizing spectroscopic probes generated in situ. Biochemistry 1979; 18: 22102218.
  • 28
    Wenzel E, Machen TE. Intracellular pH dependance of buffer capacity and anion exchange in the parietal cell. Am J Physiol 1989; 257: G741G747.
  • 29
    Weintraub WH, Machen TE. pH regulation in hepatoma cells: roles for Na+/H+ and Cl-/HCO3- exchange and for Na+:HCO3- symport. Am J Physiol 1989; 257: G317G327.
  • 30
    Boron WF. Control of intracellular pH. In: TavoloniN, BerkPD, eds. The Kidney: Physiology and Pathophysiology. 2nd ed. New York: Raven, 1992: 219263.
  • 31
    Benedetti A, Strazzabosco M, Corasanti JC, Haddad P, Graf J, Boyer JL. Cl-/HCO3-exchanger in isolated rat hepatocytes: role in regulation of intracellular pH. Am J Physiol 1991; 261: G512G522.
  • 32
    Benedetti A, Strazzabosco M, Ng OC, Boyer JL. Regulation of activity and apical targeting of the C1/HCO3 exchanger in rat hepatocytes. Proc Natl Acad Sci U S A 1994; 91: 792796.
  • 33
    Martinez-Ansò E, Castillo JE, Diez J, Medina JE, Prieto J. Immunohisto-chemical detection of chloride/bicarbonate anion exchangers in human liver. Hepatology 1994; 19: 14001406.
  • 34
    Ganz MB, Boyarsky G, Sterzel BR, Boron WF. Arginine vasopressin enhances pHi regulation in the presence of HCO3- by stimulating three acid/ base transport systems. Nature 1989; 337: 648651.
  • 35
    Fitz JG, Basavappa S, McGill J, Melhus O, Cohn JA. Regulation of membrane chloride currents in rat bile duct epithelial cells. J Clin Invest 1993; 91: 319328.
  • 36
    Alvaro D, Delia Guardia P, Bini A, Gigliozzi A, Furfaro S, La Rosa T, Piat C, et al. Effect of glucagon on intracellular pH regulation in isolated rat hepatocyte couplets. J Clin Invest 1995; 96: 665675.
  • 37
    Bear CE, Reyes EF. cAMP-activated chloride conductance in the colonic cell line, Caco-2. Am J Physiol 1992; 262: C251C256.
  • 38
    Gray MA, Winpenny JP, Porteous DJ, Dorin JR, Argent BE. CFTR and calcium-activated chloride currents in pancreatic duct cells of a transgenic CF mouse. Am J Physiol 1994; 266: C213C221.
  • 39
    Gray MA, Plant S, Argent BE. cAMP regulated whole cell chloride currents in pancreatic duct cells. Am J Physiol 1993; 264: C591C602.
  • 40
    Villanger O, Veel T, Raeder MG. Secretin causes H+ secretion from intra-hepatic bile ductules by vacuolar H+ ATPase. Am J Physiol 1993; 265: G719G724.
  • 41
    Alpini G, Roberts S, Kuntz SM, Ueno Y, Gubba S, Padula PV, LeSage G, et al. Morphological, molecular and functional heterogeneity of cholangiocytes from normal rat liver. Gastroenterology 1996; 110: 16361643.
  • 42
    Fabris L, Strazzabosco M, Martinez-Anso E, Medina J, Prieto J, Auth M, Strain A, et al. Phenotypic characterization of human biliary epithelial cells (BEG) in situ and in vitro [Abstract]. Hepatology 1995; 22: 414A.
  • 43
    Gleeson D, Smith ND, Boyer JL. Bicarbonate-dependent and -independent intracellular pH regulatory mechanisms in rat hepatocytes. Evidence for Na:HCO3 cotransport. J Clin Invest 1989; 84: 312321.
  • 44
    Marti U, Elsing C, Renner EL, Liechti-Gallati S, Reichen J. Differential expression of Na+,H+-antiporter mRNA in biliary epithelial cells and in hepatocytes. J Hepatol 1996; 24: 498502.
  • 45
    Singh SK, Boron WF, Cavestro GM, Boyer JL. Distinct apical and basolateral Na-H exchangers in isolated perfused intrahepatic bile ducts. Proceedings of the International Falk Workshop: Vanishing Bile Duct Syndrome - Pathophysiology and Treatment. June 1996, Spoleto, Italy.
  • 46
    Putnam RW. pH regulatory transport systems in a smooth muscle-like cell line. Am J Physiol 1990; 258: C470C479.
  • 47
    Tobey NA, Reddy SP, Khalbuss WE, Silvers SM, Cragoe EJ, Orlando RC. Na+-dependent and -independent C1-/HCO3- exchangers in cultured rabbit esophageal epithelial cells. Gastroenterology 1993; 104: 185195.
  • 48
    Emmons C, Stokes JB. Cellular actions of cAMP on HCO3- secreting cells of rabbit CCD: dependence on in vivo acid-base status. Am J Physiol 1994; 266: F528F535.
  • 49
    Kaplan DL, Boron WF. Long-term expression of c-H-ras stimulates Na-H and Na+-dependent C1-HCO3 exchange in NIH-3T3 fibroblasts. J Biol Chem 1994; 269: 41164124.
  • 50
    Reusch HP, Lowe J, Ives HE. Osmotic activation of a Na+-dependent Cl-/ HCO3- exchanger. Am J Physiol. 1995; 268: C147C153.
  • 51
    Buanes T, Grotmol T, Landsverk T, Raeder MG. Secretin empties bile duct cell cytoplasm of vesicles when it initiates ductular HCO3 secretion in the pig. Gastroenterology 1988; 95: 413420.
  • 52
    Kato A, Gores JG, LaRusso NF. Secretin stimulates exocytosis in isolated bile duct epithelial cells by a cyclic AMP-mediated mechanism. J Biol Chem 1992; 267: 1552315529.
  • 53
    Cho WK, Mennone A, Boyer JL. Forskolin stimulates secretion in isolated polarized bile ductular units (IBDU) by mechanisms primarily lacking a H+-ATP-ase response - evidence for heterogeneity in biliary epithelium [Abstract]. Hepatology 1993; 18: 296A.
  • 54
    Prieto J, Qian C, Garcia N, Diez J, Medina JF. Abnormal expression of anion exchanger (AE) genes in primary biliary cirrhosis (PBC). Gastroenterology 1993; 105: 572578.
  • 55
    Roos A, Boron WF. Intracellular pH. Physiol Rev 1981; 61: 296434.