• 1
    Hagenbuch B, Stieger B, Foguet M, Lubbert H, Meier PJ. Functional expression cloning and characterization of the hepatocyte Na+/bile acid cotransport system. Proc Natl Acad Sci U S A 1991; 88: 1062910633.
  • 2
    Ananthanarayanan M, Ng OC, Boyer JL, Suchy FJ. Characterization of cloned rat liver Na(+)-bile acid cotransporter using peptide and fusion protein antibodies. Am J Physiol 1994; 267 (4 Pt l): G637643.
  • 3
    Stieger B, Hagenbuch B, Landmann L, Hochli M, Schroeder A, Meier PJ. In situ localization of the hepatocytic Na+/Taurocholate cotransporting polypeptide in rat liver. Gastroenterology 1994; 107: 17811787.
  • 4
    Gartung C, Ananthanarayanan M, Rahman M, Shuele S, Nundy S, Soroka C, Stolz A, et al. Down-regulation of expression and function of the rat liver Na/bile acid cotransporter in extrahepatic cholestasis. Gastroenterology 1996; 110: 199209.
  • 5
    Hagenbuch B, Meier PJ. Molecular cloning, chromosomal localization, and functional characterization of a human liver Na+/bile acid cotransporter. J Clin Invest 1994; 93: 13261331.
  • 6
    Ferraris R, Fiorentini T, Galatola G, Rolfo P, de la Pierre M. Diagnostic value of serum immunoreactive conjugated cholic or chenodeoxycholic acids in detecting hepatobiliary diseases. Dig Dis Sci 1987; 32: 817823.
  • 7
    Jacquemin E, Dumont M, Bernard O, Erlinger S, Hadchouel M. Evidence for defective primary bile acid secretion in children with progressive familial intrahepatic cholestasis (Byler disease). Eur J Pediatr 1994; 153: 424428.
  • 8
    Chirgwin JM, Przybyla AE, MacDonald RJ, Rutter WJ. Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease. Biochemistry 1979; 18: 52945299.
  • 9
    Connell C, Fung S, Heiner C, Bridgham J, Chakerian V, Heron E, Jones B, et al. Automated DNA sequence analysis. Biotechniques 1987; 5: 342348.
  • 10
    Novak DA, Ryckman FC, Suchy FJ. Taurocholate transport by basolateral plasma membrane vesicles isolated from human liver. Hepatology 1989; 10: 447453.
  • 11
    Bradford MM. A rapid and sensitive method for the quantitation of micro-gram quantities of proteins utilizing the principle of protein-dye binding. Anal Biochem 1976; 72: 248254.
  • 12
    Shneider BL, Dawson PA, Christie DM, Hardikar W, Wong MH, Suchy FJ. Cloning and molecular characterization of the ontogeny of a rat ileal sodium-dependent bile acid transporter. J Clin Invest 1995; 95: 745754.
  • 13
    Sun AQ, Ananthanarayanan M, Suchy FJ. Heterologous expression of human liver Na+-bile acid cotransporter in cos cells exhibits kinetics similar to membrane vesicles [Abstract]. Gastroenterology 1996; 110: 1337A.
  • 14
    Wong MH, Oelkers P, Dawson PA. Identification of a mutation in the ileal sodium-dependent bile acid transporter gene that abolishes transport activity. J Biol Chem 1995; 270: 2722827234.
  • 15
    Riely CA. Familial intrahepatic cholestatic syndromes. Semin Liver Dis 1987; 7: 119133.
  • 16
    Connolly CS, Kantor GR, Menduke H. Hepatobiliary pruritus: What are effective treatments? J Am Acad Dermatol 1995; 33: 801805.
  • 17
    Kullak-Ublick GA, Hagenbuch B, Stieger B, Wolkoff AW, Meier PJ. Functional characterization of the basolateral rat liver organic anion transporting polypeptide. Hepatology 1994; 20: 411416.
  • 18
    Kullak-Ublick GA, Hagenbuch B, Stieger B, Schteingart CD, Hofmann AF, Wolkoff AW, Meier PJ. Molecular and functional characterization of an organic anion transporting polypeptide cloned from human liver. Gas-troenterology 1995; 109: 12741282.
  • 19
    Hagenbuch B, Scharschmidt BF, Meier PJ. Effect of antisense oligonucleo-tides on the expression of hepatocellular bile acid and organic anion uptake systems in Xenopus laevis oocytes. Biochem J 1996; 316: 901904.
  • 20
    Whitington PF. Chronic cholestasis of infancy. In: LebenthalE, ed. Pediat-ric Gastroenterology I, The Pediatric Clinics of North America. Philadelphia: Saunders, 1996: 126.
  • 21
    Simister NE, Mostov KE. An Fc receptor structurally related to MHC class I antigens. Nature 1989; 337: 184187.
  • 22
    Alagille D, Estrada A, Hadchouel M, Gautier M, Odievre M, Dommergues JP. Syndromic paucity of interlobular bile ducts (Alagille syndrome or arteriohepatic dysplasia): Review of 80 cases. J Pediatr 1987; 110: 195200.
  • 23
    Jacquemin E, Setchell KDR, O'Connell NC, Estrada A, Maggiore G, Schmitz J, Hadchouel M, et al. A new cause of progressive intrahepatic cholestasis: 3β-hydroxy-C27-steroid dehydrogenase/isomerase deficiency. J Pediatr 1994; 125: 379384.
  • 24
    Deleuze JF, Jacquemin E, Dubuisson C, Cresteil D, Dumont M, Erlinger S, Bernard O, et al. Defect of multidrug-resistance 3 gene expression in a subtype of progressive familial intrahepatic cholestasis. Hepatology 1996; 23: 904908.
  • 25
    Jenkins PB, Abou-Alfa GK, Dhermy D, Bursaux E, Feo C, Scarpa A, Lux SE, et al. A nonsense mutation in the erythrocyte band 3 gene associated with decreased mRNA accumulation in a kindred with dominant hereditary spherocytosis. J Clin Invest 1996; 97: 373380.
  • 26
    Karrer FM, Lilly JR, Stewart BA, Hall RJ. Biliary atresia registry, 1976 to 1989. J Pediatr Surg 1990; 25: 10761081.
  • 27
    Suchy FJ, Balistreri WF, Heubi JE, Searcy JE, Levin RS. Physiologic cholestasis: elevation of the primary serum bile acid concentrations in normal infants. Gastroenterology 1981; 80 (5 pt 1): 10371041.
  • 28
    von Dippe P, Amoui M, Stellwagen RH, Levy D. The functional expression of sodium-dependent bile acid transport in Madin-Darby canine kidney cells transfected with the cDNA for microsomal epoxide hydrolase. J Biol Chem 1996; 271: 1817618180.
  • 29
    Meier-Abt PJ. More Na+/bile acid cotransporters in hepatocytes? Lessons from obstructive cholestasis. Hepatology 1996; 24: 970972.