• 1
    Michaelis OE, Carswell N, Ellwood KG. Metabolic characteristics of the LA/N-cp and SHR/N-cp rat strains. In: HansenCT, MichaelisOE, eds. New Models Of Genetically Obese Rats for Studies in Diabetes, Heart Disease and Complications of Obesity. NIH Workshop, June 18–19, 1987, NIH, Bethesda 1315.
  • 2
    Bremond J, Bonte D, Orosco M. Jacquot C. Variations of plasma lipid fractions in relation to age in two models of obesity. Int J Obes 1983; 7: 467475.
  • 3
    Hadidy S, Fahdi L, Tabbakh H, Decbo M. Serum lipids and glucose in obese Syrian people. J Trop Geogr Med 1983; 8: 333336.
  • 4
    Hirsch J, Salans LB. Obesity. In: Principles and Practice of Endocrinology and Metabolism. BeckerKL, ed. Philadelphia: Lippincott, 1990: 131: 1039–1046.
  • 5
    Russel JC, Koeslag DJ, Amy RM. Dolphin PJ. Plasma lipid secretion and clearance in hyperlipidemic JRC:LA/cp rats. Atherosclerosis 1989; 9: 869876.
  • 6
    Ellwood KC, Michaelis OE, Emberland JJ, Bhathena SJ. Hormonal and lipogenic and gluconeogenic enzymatic responses in the LA/N-cp rats. Proc Soc Exp Biol Med 1985; 179: 163167.
  • 7
    Ghosh P, Somanchi M, Lakshman MR. Regulatory enzymes of lipid metabolism in LA/N-cp rats. J Nutr Biochem 1995; 6: 348352.
  • 8
    Dolphin P. J., Amy R. M., and Russel J. C. Lipid and lipoprotein status of the LA/ N-corpulent rat. In: HansenCT, MichaelisOE, eds. New Models Of Genetically Obese Rats for Studies in Diabetes, Heart Disease and Complications of Obesity. NIH Workshop June 18–19, 1987, NIH, Bethesda: 159162.
  • 9
    Lowenstein JM. Effect of (-)-hydroxycitrate on fatty acid synthesis by rat liver in vivo. J Biol Chem 1971; 246: 629632.
  • 10
    Guynn RW, Veloso D, Veech RL. J Biol Chem 1972; 247: 73257331.
  • 11
    Brunengraber H, Boutry M, Lowenstein JM. Fatty acid and 3 β-hydroxysterol synthesis in the perfused rat liver. J Biol Chem 1973; 248: 26562669.
  • 12
    Lakshman MR, Veech RL. Measurement of rate of rat liver sterol synthesis in vivo using tritiated water. J Biol Chem 1977; 252: 46674673.
  • 13
    Lakshman MR, Berdanier CD, Veech RL. Comparative studies on lipogenesis and cholesterogenesis in lipemic BHE rats and normal Wistar rats. Arch Biochem Biophys 1977; 183: 355360.
  • 14
    Jungas RL. Fatty acid synthesis in adipose tissue incubated in tritiated water. Biochemistry 1968; 7: 37083717.
  • 15
    Halloran LG, Schwartz CC, Vlahcevic R, Nisman RM, Swell L. Evidence for HDL-free cholesterol as the primary precursor for bile acid synthesis in man. Surgery 1978; 84: 17.
  • 16
    Lakshman MR, Gupta AD, Veech RL. Effect of chronic ethanol on cholesterol and bile acid synthesis in vivo. Lipids 1978; 13: 134136.
  • 17
    Stokke KT, Norum KR. Determination of lecithin:cholesterol acyltransferase in human blood plasma. Scand J Clin Lab Invest 1970; 27: 2127.
  • 18
    Mosbach E, Rothschild MA, Bekersky I, Oratz M, Mongelli J. Bile acid synthesis in isolated rabbit liver. J Clin Invest 1971; 50: 17201730.
  • 19
    Lakshman MR, Muesing RA, LaRosa JC. Regulation of cholesterol biosynthesis and HMG-CoA reductase activity by chylomicron remnants in isolated hepatocytes and perfused liver. J Biol Chem 1981; 256: 30373043.
  • 20
    Richardson KG, Jarett L, Finke EH. Embedding in epoxy resin for ultra-thin sectioning in electron microscopy. Stain Technology 1960; 35: 313322.
  • 21
    Sokal RR, Rohlf SJ. Biometry. San Francisco: W. H. Freeman Publishing Co., 1969.
  • 22
    Malewiak MI, Griglio S, Le Liepvre X. Relationship between lipogenesis, ketogenesis and Malonyl CoA content in isolated hepatocytes from obese Zucker rats adapted to a high fat diet. Metabolism 1985; 34: 604611.
  • 23
    Clouet P, Henninger CB, Ezard J. Study of some factors controlling fatty acid oxidation in liver mitochondria. Biochem J 1986; 239: 103108.
  • 24
    Haude W, Stauske D, Volcker CE. Some aspects of lipid metabolism in the liver of Wistar rats with fat diet-induced obesity. Nahrung 1985; 29: 567576.
  • 25
    Vance JE, Russell JC. Hypersecretion of VLDL, but nor HDL, by hepatocytes from JCR:LA corpulent rat. J Lipid Res 1990; 31: 14911501.
  • 26
    Azain MJ, Fuckuda N, Chao FF, Yamamoto M, Ontko JA. Contributions of fatty acid and sterol synthesis to triglycerides and cholesterol secretion by the perfused rat liver in genetic hyperlipidemia and obesity. J Biol Chem 1985; 260: 174181.
  • 27
    Turley SD, Hansen CT. Rates of sterol synthesis in the liver and extra hepatic tissues of the SHR/ N-corpulent rat, an animal with hyperlipidemia and insulin independent diabetes. J Lipid Res 1986; 27: 486496.
  • 28
    Cohn JS, Nestel PH, Turley SD. Metabolism of high density lipoprotein in the hyperlipidemic, diabetic SHR/N-cp rat. Metabolism 1987; 36: 230236.
  • 29
    Angel A. Cholesterol and obesity. In: BrayGA, ed. Obesity in Perspective. Volume 2. Washington, DC: U. S. Government Printing Office, 1976: 265272.
  • 30
    Gerhard RL, Levine AS, Prigge WF, Brown DM, Handwerger BS, Morley JE. Hepatic and intestinal 3-hydroxy-3-methylglutaryl coenzyme A reductase activity in genetically diabetic mice. Biochem Biophys Res Commun 1983; 113: 638644.
  • 31
    Triscari J, Bryce GF, Sullivan AC. Metabolic consequences of fasting in old and lean Zucker rats. Metabolism 1980; 29: 377385.
  • 32
    Pector JC, Winand J, Dehaye JP, Leclereq-Meyer V, Christophe J. Effects of portacaval shunt on the genetically Obese Zucker rat. Gastroenterology 1981; 81: 932937.
  • 33
    McNamara DJ. Cholesterol homeostasis in lean and obese male Zucker rat. Metabolism 1985; 34: 130135.
  • 34
    Turley SD, Spady DK, Dietschy JM. Alteration of the degree of biliary cholesterol saturation in the hamster and rat by manipulation of the pools of preformed and newly synthesized cholesterol. Gastroenterology 1983; 84; 5364.
  • 35
    Nestel PJ, Schreibman PH, Ahrens EH. Cholesterol metabolism in human obesity. J Clin Invest 1973; 52: 23892397.
  • 36
    Leijd B. Cholesterol and bile acid metabolism in obesity. Clin Sci 1980; 59: 203206.
  • 37
    Angel A, Bray GA. Synthesis of fatty acid and cholesterol by liver, adipose tissue and intestinal mucosa from obese and control patients. Eur J Clin Invest 1979; 9: 355362.
  • 38
    Danielsson H. Relationship between diurnal variations in biosynthesis of cholesterol and bile acids. Steroids 1972; 20: 6372.
  • 39
    Lakshman MR, Veech RL. Short and long-term effects of ethanol in vivo on rat liver HMG-CoA reductase and cholesterol 7a-hydroxylase activities. J Lipid Res 1977; 18: 325330.
  • 40
    Turley SD, Whiting MJ. Regulation of bile acid pool size and plasma lipid levels in the SHR/ N-cp rat. Influence of caloric intake. Metabolism 1988; 37: 2227.
  • 41
    Turley SD. Disproportional changes in the rates of biliary bile acid, phospholipid and cholesterol secretion in the SHR/N-cp rat. Biochem Biophys Acta 1986; 879: 2835.