• 1
    Linnen J, Wages J Jr., Zhang–Keck Z–Y, Fry KE, Krawczynski KZ, Alter H, Koonin E, et al. Molecular cloning and disease association of hepatitis G virus: a transfusion–transmissible agent. Science 1996; 271: 505508.
  • 2
    Simons JN, Leary TP, Dawson GJ, Pilot–Matias TJ, Muerhoff AS, Schlauder GG, Desai SM, et al. Isolation of novel virus–like sequences associated with human hepatitis. Nat Med 1995; 1: 564569.
  • 3
    Leary TP, Muerhoff SM, Simons JN, Pilot–Matias TJ, Erker JC, Chalmers ML, Schlauder GG, et al. Sequence and genomic organization of GBV– C: a novel member of the flaviviridae associated with human non–A–E hepatitis. J Med Virol 1996; 48: 6067.
  • 4
    Feucht HH, Zöllner B, Laufs R. Comparison of conventional autoradiog–raphy with a new DNA enzyme immunoassay for the detection of hepatitis C virus–polymerase chain reaction amplification products. J Virol Methods 1995; 55: 105110.
  • 5
    Reuter D, Polywka S, Iske L, Feucht HH, Laufs R. Close correlation between hepatitis C virus serology and polymerase chain reaction in chronically infected patients. Infection 1992; 20: 320323.
  • 6
    Choo QL, Richman KH, Han JH, Berger K, Lee C, Dong D, Gallegos C, et al. Genetic organization and diversity of the hepatitis C virus. Proc Natl Acad Sci U S A 1991; 88: 24512455.
  • 7
    Sanger F, Nicklen S, Coulson AR. DNA sequencing with chain terminating inhibitors. Proc Natl Acad Sci U S A 1977; 74: 54635467.
  • 8
    Feucht HH, Zöllner B, Polywka S, Laufs R. Study on the reliability of commercially available hepatitis C virus antibody tests. J Clin Microbiol 1995; 33: 620624.
  • 9
    Marin MG, Bresciani S, Puoti M, Rodella A, Gussago A, Ravaggi A, et al. Clinical significance of serum hepatitis C virus (HCV) RNA as marker of HCV infection. J Clin Microbiol 1994; 32: 30083012.
  • 10
    Young KKY, Archer JJ, Yokosuka O, Omata M, Resnick RM. Detection of hepatitis C virus RNA by a combined reverse transcription PCR assay: comparison with nested amplification and antibody testing. J Clin Microbiol 1995; 33: 654657.
  • 11
    Dawson GJ, Schlauder GG, Coleman P, Gabriel G, Anderson D, Leahy D, Desai SM, et al. Prevalence and clinical significance of GBV–C [Abstract]. IX triennial international symposium on viral hepatitis and liver disease, Rome 1996, abstract 116.
  • 12
    Miller RH, Purcell RH. Hepatitis C virus shares amino acid sequence similarity with pestiviruses and flaviviruses as well as members of two plant virus supergroups. Proc Natl Acad Sci U S A 1990; 87: 20572061.
  • 13
    Ohba K, Mizokami M, Lau JY, Orito E, Ikeo K, Gojobori T. Evolutionary relationship of hepatitis C, pesti–, flavi–, plantviruses, and newly discovered GB hepatits agents. FEES Lett 1996; 378: 232234.
  • 14
    Jarvis LM, Davidson F, Hanley JP, Yap PL, Ludiam CA, Simmonds P. Infection with hepatitis G virus among recipients of plasma. Lancet 1996; 348: 13521355.
  • 15
    Dawson GJ, Lesniewski RR, Stewart JL, Boardway KM, Guitierrez RA, Pendy L, Johnson RG, et al. Detection of antibodies to hepatitis C virus in U. S. blood donors. J Clin Microbiol 1991; 29: 551556.
  • 16
    Alter MJ, Margolis HS, Krawczynski K, Judson FN, Mares A, Alexander WJ, Hu PY, et al. The natural history of community– acquired hepatitis C in the United States. N Engl J Med 1992; 327: 18991905.
  • 17
    Liang TJ, Bodenheimer HC Jr., Yankee R, Brown NV, Chang K, Huang J, Wands JR. Presence of hepatitis B and C viral genomes in US blood donors as detected by polymerase chain reaction amplification. J Med Virol 1994; 42: 151157.
  • 18
    Crawford RJ, Gillon J, Yap PL, Brookes E, McOmish F, Simmonds P, Dow BC, et al. Prevalence and epidemiological characteristics of hepatitis C in Scottish blood donors. Transfus Med 1994; 4: 121124.
  • 19
    Schmidt B, Korn K, Fleckenstein B. Molecular evidence for transmission of hepatitis G virus by blood transfusion. Lancet 1996; 347: 909.
  • 20
    Feucht HH, Zöllner B, Polywka S, Laufs R. Vertical transmission of hepatitis G. Lancet 1996; 347: 615616.
  • 21
    Feucht HH, Polywka S, Zollner B, Laufs R. Greater amount of HCV–RNA in tears compared to blood. Microbiol Immunol 1994; 38: 157158.
  • 22
    Feucht HH, Zöllner B, Schröter M, Altrogge H, Laufs R. Tear fluid of hepatitis C virus carriers could be infectious. J Clin Microbiol 1995; 33: 22022203.
  • 23
    Yoshiba M, Okamoto H, Mishiro S. Detection of the GBV–C hepatitis virus in serum from patients with fulminant hepatitis of unknown aetiology. Lancet 1995; 346: 11311132.
  • 24
    Zaidi Y, Chapman CS, Myint S. Aplastic anaemia after HGV infection. Lancet 1996; 348: 471472.
  • 25
    Heringlake S, Osterkamp S, Trautwein C, Tillmann HL, Boker K, Muerhoff S, Mushawar IK, et al. Association between fulminant hepatic failure and a strain of GBV virus C. Lancet 1996; 348: 16261629.
  • 26
    Feucht HH, Fischer L, Sterneck M, Knödler B, Broelsch CE, Laufs R. GB virus C infection and liver transplantation: increased risk of transfusion–transmitted infection. Blood 1997; 89: 22232224.