• 1
    Krause DS, Fackler MJ, Civin CI, May WS. CD34: structure, biology, and clinical utility. Blood 1996; 87: 113.
  • 2
    Fackler MJ, Krause DS, Smith OM, Civin CI, May WS. Full-length but not truncated CD34 inhibits hematopoietic cell differentiation of M1 cells. Blood 1995; 85: 30403047.
  • 3
    Simmoms DL, Satterthwaite AB, Tenen DG, Seed B. Molecular cloning of a cDNA encoding CD34, a sialomucin of human hematopoietic stem cells. J Immunol 1991; 148: 267271.
  • 4
    He XY, Antao VP, Basila D, Marx JC, Davis BR. Isolation and molecular characterization of human CD34 gene. Blood 1992; 79: 22962302.
  • 5
    Brown J, Greaves MF, Molgaard HV. The gene encoding the stem cell antigen, CD34, is conserved in mouse and expressed in haematopoietic progenitor cell lines, brain, and embryonic fibroblasts. Int Immunol 1991; 3: 175184.
  • 6
    Suda J, Sudo T, Ito M, Ohno N, Yamaguchi Y, Suda T. Two types of murine CD34 mRNA generated by alternative splicing. Blood 1992; 79: 22882295.
  • 7
    Krause DS, Ito T, Fackler MJ, Smith OM, Collector MI, Sharkis SJ, May WS. Characterization of murine CD34, a marker for hematopoietic progenitor and stem cells. Blood 1994; 84: 691701.
  • 8
    McSweeney PA, Rouleau KA, Storb R, Bolles L, Wallace PM, Beauchamp M, Krizanac-Bengez L, et al. Canine CD34: cloning of the cDNA and evaluation of an antiserum to recombinant protein. Blood 1996; 88: 19922003.
  • 9
    Grisham JW, Thorgeirsson SS. Liver stem cells. In: PottenCS, ed. Stem Cells. London: Academic Press, 1997: 233282.
  • 10
    Evarts RP, Nagy P, Nakatsukasa H, Marsden ER, Thorgeirsson SS. In vivo differentiation of rat liver oval cells into hepatocytes. Cancer Res 1989; 49: 15411547.
  • 11
    McMahon JB, Richards WL, del Campo AA, Song M, Thorgeirsson SS. Differential effects of transforming growth factor-α on proliferation of normal and malignant rat liver epithelial cells in culture. Cancer Res 1986; 46: 46654671.
  • 12
    Altschul SF, Gish W, Miller W, Myers EW, Lipman DJ. Basic local alignment search tool. J Mol Biol 1990; 215: 403410.
  • 13
    Fort P, Marty L, Piechaczyk M, El Sabrouty S, Dani C, Jeanteur P, Blanchard JM. Various rat adult tissues express only one major mRNA species from the glyceraldehyde-3-phosphate-dehydrogenase multigenie family. Nucleic Acids Res 1985; 13: 14311442.
  • 14
    Omori N, Evarts RP, Omori M, Marsden ER, Thorgeirsson SS. Expression of leukemia inhibitory factor and its receptor during liver regeneration in the adult rat. Lab Invest 1996; 75: 1524.
  • 15
    Lammie A, Drobnjak M, Gerald W, Saad A, Cote R, Cordon-Cardo C. Expression of c-kit and kit ligand proteins in normal human tissue. J Histochem Cytochem 1994; 42: 14171425.
  • 16
    Evarts RP, Nakatsukasa H, Marsden ER, Hu Z, Thorgeirsson SS. Expression of transforming growth factor-α in regenerating liver during hepatic differentiation. Mol Carcinog 1992; 5: 2531.
  • 17
    Blakolmer K, Jaskiewicz K, Dunsford HA, Robson SC. Hematopoietic stem cell markers are expressed by ductal plate and bile duct cells in developing human liver. Hepatology 1995; 21: 15101516.
  • 18
    Taniguchi H, Toyoshima T, Fukao K, Nakauchi H. Presence of hematopoietic stem cells in the adult liver. Nat Med 1996; 2: 198203.
  • 19
    Watanabe H, Miyaji C, Seki S, Abo T. C-Kit+ stem cells and thymocyte precursors in the liver of adult mice. J Exp Med 1996; 184: 687693.
  • 20
    Fujio K, Evarts RP, Hu Z, Marsden ER, Thorgeirsson SS. Expression of stem cell factor and its receptor, c-kit, during liver regeneration from putative stem cells in adult rat. Lab Invest 1994; 70: 511516.
  • 21
    Briddel RA, Broudhy VC, Bruno E, Brandt JE, Srour EF, Hoffman R. Further phenotypic characterization and isolation of human hematopoietic progenitor cells using monoclonal antibody to c-kit receptor. Blood 1992; 79: 31593167.
  • 22
    Fujio K, Hu Z, Evarts RP, Marsden ER, Niu CH, Thorgeirsson SS. Coexpression of stem cell factor and c-kit in embryonic and adult liver. Exp Cell Res 1996; 224: 243250.
  • 23
    Osawa M, Hanada K, Hamada H, Nakauchi H. Long-term lymphohematopoietic reconstitution by a single CD34-low/negative hematopoietic stem cell. Science 1996; 273: 242245.
  • 24
    Nagy P, Evarts RP, Marsden ER, Roach J, Thorgeirsson SS. Cellular distribution of c-myc transcripts during chemical hepatocarcinogenesis in rats. Cancer Res 1988; 48: 55225527.
  • 25
    Lin G, Finger E, Gutierrez-Ramos JC. Expression of CD34 in endothelial cells, hematopoietic progenitors and nervous cells in fetal and adult mouse tissues. Eur J Immunol 1995; 25: 15081516.
  • 26
    Baumhueter S, Dybdal N, Lasky LA. Global vascular expression of murine CD34, a sialomucin-like endothelial ligand for L-selectin. Blood 1994; 84: 25542565.
  • 27
    Young PE, Baumhueter S, Lasky LA. The sialomucin CD34 expressed on hematopoietic cells and blood vessels during murine development. Blood 1995; 85: 96105.
  • 28
    Couvelard A, Scoazec JY, Dauge MC, Bringuier AF, Potet F, Feldman G. Structural and functional differentiation of sinusoidal endothelial cells during liver organogenesis in humans. Blood 1996; 87: 45684580.
  • 29
    Couvelard A, Scoazec JY, Feldman G. Expression of cell-cell and cell-matrix adhesion proteins by sinusoidal endothelial cells in the normal and cirrhotic human liver. Am J Pathol 1993; 143: 738752.
  • 30
    Ito A, Nomura S, Hirota S, Suda J, Suda T, Kitamura Y. Enhanced expression of CD34 messenger RNA by developing endothelial cells of mice. Lab Invest 1995; 72: 532538.
  • 31
    Jaskiewicz K, Chasen MR. Differential expression of transforming growth factor alpha, adhesion molecules and integrins in primary, metastatic liver tumors and in liver cirrhosis. Anticancer Res 1995; 15: 559562.
  • 32
    Ruck P, Xiao JC, Kaiserling E. Immunoreactivity of sinusoids in hepatocellular carcinoma. Arch Pathol Lab Med 1995; 119: 173178.
  • 33
    Maeda T, Adachi E, Kajiyama K, Takenaka K, Honda H, Sugirnachi K, Tsuneyoshi M. CD34 expression in endothelial cells of small hepatocellular carcinoma: Its correlation with tumor progression and angiographic findings. J Gastroenterol Hepatol 1995; 10: 650654.
  • 34
    Fackler MJ, Civin CI, May WS. Upregulation of surface CD34 is associated with protein kinase C-mediated hyperphosphorylation. J Biol Chem 1992; 267: 1754017546.
  • 35
    Baumhueter S, Singer MS, Henzel W, Hemmerich S, Renz M, Lasky LA. Binding of L-selectin to the vascular sialomucin CD34. Science 1993; 262: 436438.
  • 36
    Cheng L, Baumhueter S, Cacalano G, Carver-Moore K, Thibodeaux H, Thomas R, Broxmeyer HE, et al. Hematopoietic defects in mice lacking the sialomucin CD34. Blood 1996; 87: 479490.
  • 37
    Healy L, May G, Gale K, Grosveld F, Greaves M, Enver T. The stem cell antigen CD34 functions as a regulator of hemopoietic cell adhesion. Proc Natl Acad Sci U S A 1995; 92: 1224012244.
  • 38
    Hu Z, Evarts RP, Fujio K, Marsden ER, Thorgeirsson SS. Expression of hepatocyte growth factor and c-met genes during hepatic differentiation and liver development in the rat. Am J Pathol 1993; 142: 18231830.
  • 39
    Marsden ER, Hu Z, Fujio K, Nakatsukasa H, Thorgeirsson SS, Evarts RP. Expression of acidic fibroblast growth factor in regenerating liver and during hepatic differentiation. Lab Invest 1992; 67: 427433.