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What strategy should be used for diagnosis of hepatitis C virus infection in clinical laboratories?

  1. Jean-Michel Pawlotsky M.D., Ph.D.1,2,*,
  2. Isabelle Lonjon3,
  3. Christophe Hezode3,
  4. Bruno Raynard3,
  5. Francoise Darthuy1,
  6. Jocelyne Remire1,
  7. Claude-James Soussy1,
  8. Daniel Dhumeaux2,3

Article first published online: 30 DEC 2003

DOI: 10.1002/hep.510270632

Issue

Hepatology

Hepatology

Volume 27, Issue 6, pages 1700–1702, June 1998

Additional Information

How to Cite

Pawlotsky, J.-M., Lonjon, I., Hezode, C., Raynard, B., Darthuy, F., Remire, J., Soussy, C.-J. and Dhumeaux, D. (1998), What strategy should be used for diagnosis of hepatitis C virus infection in clinical laboratories?. Hepatology, 27: 1700–1702. doi: 10.1002/hep.510270632

Author Information

  1. 1

    Department of Bacteriology and Virology, Hôpital Henri Mondor, Université Paris XII, Créteil, France

  2. 2

    INSERM U99, Hôpital Henri Mondor, Université Paris XII, Créteil, France

  3. 3

    Department of Hepatology and Gastroenterology, Hôpital Henri Mondor, Université Paris XII, Créteil, France.

*Service de Bactériologie-Virologie, Hôpital Henri Mondor, 51 avenue du maréchal de Lattre de Tassigny, 94010 Creteil, France. Fax: 33-1-49-81-28-39.

Publication History

  1. Issue published online: 30 DEC 2003
  2. Article first published online: 30 DEC 2003
  3. Manuscript Accepted: 6 FEB 1998
  4. Manuscript Received: 26 NOV 1997

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REFERENCES

  • 1
    Weiner AJ, Truett MA, Rosenblatt J, Han J, Quan S, Polito A, Kuo G, et al. HCV testing in low-risk population. Lancet 1990; 336:695.MEDLINE
  • 2
    Lok ASF, Ma OCK, Chan TM, Lai CL, Chung HT, Ng CPL, Lam JSC. Overestimation of the prevalence of antibody to hepatitis C virus in retrospective studies on stored sera. Hepatology 1991; 14:756–762.MEDLINE
    Direct Link:
  • 3
    Alter HJ. New kit on the block: evaluation of second-generation assays for detection of antibody to the hepatitis C virus. Hepatology 1992; 15:350–353.MEDLINE
    Direct Link:
  • 4
    Chaudary RK, McLean C. Detection of antibody to hepatitis C virus by second-generation enzyme immunoassay. Am J Clin Pathol 1993; 99:702–704.MEDLINE
  • 5
    Farci P, London WT, Wong DC, Dawson GJ, Vallari DS, Engle R, Purcell RH. The natural history of infection with hepatitis C virus (HCV) in chimpanzees: comparison of serologic responses measured with first- and second-generation assays and relationship to HCV viremia. J Infect Dis 1992; 165:1006–1011.MEDLINE
  • 6
    Huber KR, Sebesta C, Bauer K. Detection of common hepatitis C virus subtypes with a third-generation enzyme immunoassay. Hepatology 1996; 24:471–473.MEDLINE
    Direct Link:
  • 7
    van der Poel CL, Cuypers HTM, Reesink HW, Weiner AJ, Quan S, di Nello R, van Boven JJP, et al. Confirmation of hepatitis C virus infection by new four-antigen recombinant immunoblot assay. Lancet 1991; 337:317–319.MEDLINE
  • 8
    Pawlotsky JM. Significance of indeterminate second-generation RIBA and resolution by third-generation RIBA. In: GroupeFran çais d'Etudes Moléculaires des Hépatites (GEMHEP), ed. Hepatitis C Virus: New Diagnostic Tools. Paris: John Libbey Eurotext, 1994;17–28.
  • 9
    Couroucé AM. Evolution of the successively introduced anti-HCV test kits and their compared performances. In: GhnassiaJC, HarzicM, MaisonneuveP, NoëlL, eds. XIe Colloque de Virologie de Versailles-Le Chesnay. Paris: Elsevier, 1997:69–74.
  • 10
    Sayers MH, Gretch DR. Recombinant immunoblot and polymerase chain reaction testing in volunteer whole blood donors screened by a multi-antigen assay for hepatitis C virus antibodies. Transfusion 1993; 33:809–813.MEDLINE
    Direct Link:
  • 11
    Pawlotsky JM. Chronic hepatitis C virus infection with repeatedly normal aminotransferase levels: disease or not disease? Am J Gastroenterol 1997; 92:1775–1777.MEDLINE
  • 12
    Dhumeaux D, Doffoël M, Galmiche JP. A French consensus conference on hepatitis C: screening and treatment. J Hepatol 1997; 27:941–944.MEDLINE
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