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References

  • 1
    Akahane Y, Yamanaka T, Suzuki H, Sugai Y, Tsuda F, Yotsumoto S, Omi S, et al. Chronic active hepatitis with hepatitis B virus DNA and antibody against e antigen in the serum. Disturbed synthesis and secretion of e antigen from hepatocytes due to a point mutation in the precore region. Gastroenterology 1990; 99:11131119.MEDLINE
  • 2
    Brunetto MR, Giarin MM, Oliveri F, Chiaberge E, Baldi M, Alfarano A, Serra A, et al. Wild-type and e antigen–minus hepatitis B viruses and course of chronic hepatitis. Proc Natl Acad Sci U S A 1991; 88:41864190.MEDLINE
  • 3
    Carman WF, Hadziyannis S, McGarvey MJ, Jacyna MR, Karayiannis P, Makris A, Thomas HC. Mutation preventing formation of hepatitis B e antigen in patients with chronic hepatitis B infection. Lancet 1989; ii:588590.
  • 4
    Lok ASF, Akarca U, Greene S. Mutations in the pre-core region of hepatitits B virus serve to enhance the stability of the secondary structure of the pre-genome encapsidation signal. Proc Natl Acad Sci U S A 1994; 91:40774081.MEDLINE
  • 5
    Okamoto H, Yotsumoto S, Akahane Y, Yamanaka T, Miyazaki Y, Sugai Y, Tsuda F, et al. Hepatitis B viruses with precore region defects prevail in persistently infected hosts along with seroconversion to the antibody against e antigen. J Virol 1990; 64:12981303.MEDLINE
  • 6
    Takeda K, Akahane Y, Suzuki H, Okamoto H, Tsuda F, Miyakawa Y, Mayumi M. Defects in the precore region of the HBV genome in patients with chronic hepatitis B after sustained seroconversion from HBeAg to anti-HBe induced spontaneously or with interferon therapy. Hepatology 1990; 12:12841289.MEDLINE
  • 7
    Hamasaki K, Nakata K, Nagayama Y, Ohtsuru A, Daikoku M, Taniguchi K, Tsutsumi T, et al. Changes in the prevalence of HBeAg-negative mutants hepatitis B virus during the course of chronic hepatitis B. Hepatology 1994; 20:814.MEDLINE
  • 8
    Li JS, Tong SP, Wen YM, Vitvitski L, Zhang Q, Trepo C. Hepatitis B virus genotype A rarely circulates as an HBe-minus mutant: possible contribution of a single nucleotide in the precore region. J Virol 1993; 67:54025410.MEDLINE
  • 9
    Rodriguez-Frias F, Buti M, Jardi R, Cotrina M, Viladomiu L, Esteban R, Guardia J. Hepatitis B virus infection: precore mutants and its relation to viral genotypes and core mutations. Hepatology 1995; 22:16411647.MEDLINE
  • 10
    Lindh M, Andersson AS, Gusdal A. Genotypes, nt 1858 variants, and geographic origin of hepatitis B virus—large-scaled analysis using a new genotyping method. J Infect Dis 1997; 175:12851293.MEDLINE
  • 11
    Lok ASF, Akarca US, Greene S. Predictive value of precore hepatitis B virus mutations in spontaneous and interferon-induced hepatitis B e antigen clearance. Hepatology 1995; 21:1924.MEDLINE
  • 12
    Okamoto H, Tsuda F, Akahane Y, Sugai Y, Yoshiba M, Moriyama K, Tanaka T, et al. Hepatitis B virus with mutations in the core promoter for an e antigen-negative phenotype in carriers with antibody to e antigen. J Virol 1994; 68:81028110.MEDLINE
  • 13
    Kidd-Ljunggren K, Oberg M, Kidd AH. Hepatitis B virus X gene 1751 to 1764 mutations: implications for HBeAg status and disease. J Gen Virol 1997; 78:14691478.MEDLINE
  • 14
    Kurosaki M, Enomoto N, Asahina Y, Sakuma I, Ikeda T, Tozuka S, Izumi N, et al. Mutations in the core promoter region of hepatitis B virus in patients with chronic hepatitis B. J Med Virol 1996; 49:115123.MEDLINE
  • 15
    Horikata M, Itoh V, Yamamoto K, Shibayama T, Tsuda F, Okamoto H. Differences in the entire nucleotide sequence between hepatitis B virus genomes from carriers positive for antibody to hepatitis B e antigen with and without active disease. J Med Virol 1994; 44:96103.MEDLINE
  • 16
    Buckwold VE, Xu Z, Chen M, Yen TSB, Ou JH. Effects of a naturally occurring mutation in the hepatitis virus basal core promoter on precore gene expression and viral replication. J Virol 1996; 70:58455851.MEDLINE
  • 17
    Scaglioni PP, Melegari M, Wands JR. Biological properties of hepatitis B viral genomes with mutations in the precore promoter and precore open reading frame. Virology 1997; 233:374381.MEDLINE
  • 18
    Gunther S, Piwon N, Will H. Wild type levels of pregenomic RNA and replication but reduced pre-C RNA and e-antigen synthesis of hepatitis B virus with C(1653)-T, A(1762) -T, and G(1764)-A mutations in the core promoter. J Gen Virol 1998; 79:375380.MEDLINE
  • 19
    Moriyama K, Okamoto H, Tsuda F, Mayumi M. Reduced precore transcription and enhanced core-pregenome transcription of hepatitis B virus DNA after replacement of the precore-core promoter with sequences associated with e antigen-seronegative persistent infections. Virology 1996; 226:269280.MEDLINE
  • 20
    Nishizono A, Hiraga M, Kohno K, Sonoda YT, Terao H, Fujioka T, Nasu M, et al. Mutations in the core promoter/enhancer II regions of naturally occurring hepatitis B virus variants and analysis of the effects on transcription activities. Intervirology 1995; 38:290294.MEDLINE
  • 21
    Liang TJ, Hasegawa K, Rimon N, Wands JR, Ben-Porath B. A hepatitis B virus mutant associated with an epidemic of fulminant hepatitis. N Engl J Med 1991; 324:17051709.MEDLINE
  • 22
    Omata M, Ehata T, Yokosuka O, Hosoda K, Ohto M. Mutations in the precore region of hepatitis B virus DNA in patients with fulminant and severe hepatitis. N Engl J Med 1991; 324:16991704.MEDLINE
  • 23
    Tur-Kaspa R, Klein A, Aharonson S. Hepatitis B virus precore mutants are identical in carriers from various ethnic origins and are associated with a range of liver disease severity. Hepatology 1992; 16:13381342.MEDLINE
  • 24
    Akarca US, Greene S, Lok ASF. Detection of precore hepatitis B virus mutants in asymptomatic HBsAg-positive family members. Hepatology 1994; 19:13661370.MEDLINE
  • 25
    Sato S, Suzuki K, Akahane Y, Akamatsu K, Akiyama K, Yunomura K, Tsuda F, et al. Hepatitis B virus strain with mutation in the core promoter in patients with fulminant hepatitis. Ann Intern Med 1995; 122:241248.MEDLINE
  • 26
    Lok ASF, Lai CL, Wu PC, Leung EKY. Long-term follow-up in a randomized controlled trial of recombinant alpha-interferon in Chinese patients with chronic hepatitis B infection. Lancet 1988; 2:298302.MEDLINE
  • 27
    Lok ASF, Wu PC, Lai CL, Lau JYN, Leung EKY, Wong LSK, Ma OCK, et al. A controlled trial of interferon with or without prednisone priming for chronic hepatitis B. Gastroenterology 1992; 102:20912097.MEDLINE
  • 28
    Buckwold VE, Xu Z, Yen B, Ou JH. Effects of a frequent double-nucleotide basal core promoter mutation and its putative single-nucleotide precursor mutations on hepatitis B virus gene expression and replication. J Gen Virol 1997; 78:20552065.MEDLINE
  • 29
    Laskus T, Rakela J, Nowicki MJ, Persing DH. Hepatitis B virus core promoter sequence analysis in fulminant and chronic hepatitis B. Gastroenterology 1995; 109:16181623.MEDLINE
  • 30
    Kidd AH, Kidd-Ljunggren K. A revised secondary structure model for the 3′-end of hepatitis B virus pregenomic RNA. Nucleic Acids Res 1996; 24:32953301.MEDLINE