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Diagnosis of hepatic encephalopathy: Will in vivo proton MRS play a role?

  1. Jacquelyn Maher Editor1,
  2. Rajiv Jalan M.D.2,
  3. Steven W. M. Olde Damink M.D.2,
  4. Peter C. Hayes Ph.D.2,
  5. Joanna M. Wardlaw M.D.3

Article first published online: 30 DEC 2003

DOI: 10.1002/hep.510290537

Issue

Hepatology

Hepatology

Volume 29, Issue 5, pages 1605–1607, May 1999

Additional Information

How to Cite

Maher, J., Jalan, R., Olde Damink, S. W. M., Hayes, P. C. and Wardlaw, J. M. (1999), Diagnosis of hepatic encephalopathy: Will in vivo proton MRS play a role?. Hepatology, 29: 1605–1607. doi: 10.1002/hep.510290537

Author Information

  1. 1

    San Francisco General Hospital, Building 40, Room 4102, 1001 Potrero Avenue, San Francisco, CA 94110

  2. 2

    Liver Unit, Department of Medicine, Royal Infirmary of Edinburgh, UK

  3. 3

    Department of Clinical Neuroradiology, Western General Hospital, Edinburgh, UK

Publication History

  1. Issue published online: 30 DEC 2003
  2. Article first published online: 30 DEC 2003

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References

  • 1
    Jalan R, Hayes PC. Hepatic encephalopathy and ascites. Lancet 1997; 350:1309–1315.MEDLINE
  • 2
    Kril JJ, Butterworth RF. Diencephalic and cerebellar pathology in alcoholic and nonalcoholic patients with end-stage liver disease. Hepatology 1997; 26:837–841.MEDLINE
    Direct Link:
  • 3
    Tarter RE, Switala JA, Arria A, Plail J, Van Thiel DH. Subclinical hepatic encephalopathy. Comparison before and after orthotopic liver transplantation. Transplantation 1990; 50:632–637.MEDLINE
  • 4
    Krieger S, Jauss M, Jansen O, Theilmann L, Geissler M, Krieger D. Neuropsychiatric profile and hyperintense globus pallidus on T1-weighted magnetic resonance images in liver cirrhosis. Gastroenterology 1996; 111:147–155.MEDLINE
  • 5
    Conn HO, Leevy CM, Vlahcevic ZR, Rodgers JB, Maddrey WC, Seeff L, Levy LL. Comparison of lactulose and neomycin in the treatment of chronic portal-systemic encephalopathy. A double blind controlled trial. Gastroenterology 1977; 72:573–583.MEDLINE
  • 6
    Taylor-Robinson SD, Sargentoni J, Marcus CD, Morgan MY, Bryant DJ. Regional variations in cerebral proton spectroscopy in patients with chronic hepatic encephalopathy. Metab Brain Dis 1994; 9:347–359.MEDLINE
  • 7
    Ross BD, Jacobson S, Villamil F, Korula J, Kreis R, Ernst T, Shonk T, Moats RA. Subclinical hepatic encephalopathy: proton MR spectroscopic abnormalities. Radiology 1994; 193:457–463.MEDLINE
  • 8
    Laubenberger J, Haussinger D, Bayer S, Gufler H, Kennig J, Langer M. Proton magnetic resonance spectroscopy of the brain in symptomatic and asymptomatic patients with liver cirrhosis Gastroenterology 1996; 112:1610–1616.
  • 9
    Geissler A, Lock G, Frund R, Held P, Hollerbach S, Andus T, Scholmerich J, et al. Cerebral abnormalities in patients with cirrhosis detected by proton magnetic resonance spectroscopy and magnetic resonance imaging. Hepatology 1997; 25:48–54.MEDLINE
    Direct Link:
  • 10
    Wardlaw JM, Marshall IAN, Signori DF. Serial precision of metabolite peak area ratios and water referenced metabolite peak areas in proton MR spectroscopy of the human brain. Mag Res Med (in press).
  • 11
    Elkington SG, Floch MH, Conn HO. Lactulose in the treatment of chronic portal-systemic encephalopathy. A double-blind clinical trial. N Engl J Med 1969; 281:408–412.MEDLINE
  • 12
    Simmons F, Goldstein H, Boyle JD. A controlled clinical trial of lactulose in hepatic encephalopathy. Gastroenterology 1970; 59:827–832.MEDLINE
  • 13
    Germain L, Frexinos J, Louis A, Ribet A. Double blind study of lactulose in 8 patients with chronic hepatic encephalopathy after portocaval shunt. Arch Fr Mal App Dig 1973; 62:293–302.
  • 14
    Stauch S, Kircheis G, Adler G, Beckh K, Ditschuneit H, Gortelmeyer R, Hendricks R, et al. Oral L-ornithine-L-aspartate therapy of chronic hepatic encephalopathy: results of a placebo-controlled double-blind study. J Hepatol 1998; 28:856–864.MEDLINE
  • 15
    Parsons-Smith BC, Sumerskill WHJ, Dawson AM. The electroencephalograph in liver disease. Lancet 1957; 2:867–871.
  • 16
    Oppong KN, Al-Mardini H, Thick M, Record CO. Oral glutamine challenge in cirrhotics pre- and post-liver transplantation: a psychometric and analyzed EEG study. Hepatology 1997; 26:870–876.MEDLINE
    Direct Link:
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