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Improvement in pulmonary hemodynamics during intravenous epoprostenol (prostacyclin): A study of 15 patients with moderate to severe portopulmonary hypertension
Article first published online: 30 DEC 2003
DOI: 10.1002/hep.510300307
Copyright © 1999 American Association for the Study of Liver Diseases
Additional Information
How to Cite
Krowka, M. J., Frantz, R. P., McGoon, M. D., Severson, C., Plevak, D. J. and Wiesner, R. H. (1999), Improvement in pulmonary hemodynamics during intravenous epoprostenol (prostacyclin): A study of 15 patients with moderate to severe portopulmonary hypertension. Hepatology, 30: 641–648. doi: 10.1002/hep.510300307
Publication History
- Issue published online: 30 DEC 2003
- Article first published online: 30 DEC 2003
- Manuscript Accepted: 8 JUN 1999
- Manuscript Received: 27 JAN 1999
References
- 1, , , , , , . Primary pulmonary hypertension: a national prospective study. Ann Intern Med 1987; 107:216–223. MEDLINE
- 2, , , , , , . Pulmonary vascular disorders in portal hypertension. Eur Respir J 1998; 11:1153–1166. MEDLINE
- 3, , . Distinctive clinical features of portopulmonary hypertension. Chest 1997; 112:980–986. MEDLINE
- 4, , , , , . Co-existent pulmonary and portal hypertension: morphologic and clinical features. J Am Coll Cardiol 1987; 10:1233–1238. MEDLINE
- 5. Hepatopulmonary hypertension and portopulmonary hypertension: distinctions and dilemmas. Hepatology 1997; 25:1282–1284. MEDLINEDirect Link:
- 6. Pulmonary hypertension and related diseases. In: StehbeusWE, LieJT, eds. Vascular Pathology. London: Chapman and Hall Medical, 1995; 585–621.
- 7, , , , . Portopulmonary hypertension and liver transplantation: why we fail. Hepatology 24: 585–621.
- 8, . Association between primary pulmonary hypertension and portal hypertension: analysis of its pathophysiology, clinical laboratory, and hemodynamic manifestations. J Am Coll Cardiol 1991; 17:492–499. MEDLINE
- 9
- 10, , , , , , , et al. A comparison of continuous intravenous epoprostenol (prostacyclin) with conventional therapy for primary pulmonary hypertension. N Engl J Med 1996; 334:296–301. MEDLINE
- 11, , , . Reduction in pulmonary vascular resistance with long term epoprostenol (prostacyclin) therapy in primary pulmonary hypertension. N Engl J Med 1998; 338:272–277.
- 12, , , , . Moderate to severe portopulmonary hypertension: important correlates with Doppler echocardiography in liver transplant patients. Hepatology 28: 272–277.
- 13, , , , , . Prostacyclin-induced acute pulmonary vasodilatation in primary pulmonary hypertension. Circulation 1982; 2:334–338.
- 14, , , , . A comparison of acute hemodynamic effects of prostacyclin and hydralazine in primary pulmonary hypertension. Am Heart J 1985; 110:1200–1204. MEDLINE
- 15, , . Treatment of primary pulmonary hypertension with intravenous epoprostenol (prostacyclin). Br Heart J 1987; 57:270–278. MEDLINE
- 16, , , , , , , et al. The acute administration of vasodilators in primary pulmonary hypertension. Am Rev Respir Dis 1989; 140:1623–1630. MEDLINE
- 17, , , . Prostacyclin and acetlycholine as screening agents for acute pulmonary vasodilator responsiveness in primary pulmonary hypertension. Circulation 1990; 82:2018–2026. MEDLINE
- 18, , , , , . Comparative acute effects of adenosine and prostacyclin in primary pulmonary hypertension. Chest 1995; 107:54–57. MEDLINE
- 19, , , , , , , et al. Clinical significance of pulmonary vasodilator response during short-term infusion of prostacyclin in primary pulmonary hypertension. Circulation 1996; 93:484–488. MEDLINE
- 20, . The management of primary pulmonary hypertension. JAMA 1991; 8:1014–1020.
- 21. Role of hemodynamics in pulmonary vascular remodeling. Am J Respir Crit Care Med 1999; 159:361–364. MEDLINE
- 22, , , , . Continuous infusion of epoprostenol for the treatment of portopulmonary hypertension. Transplantation 1997; 63:604–606. MEDLINE
- 23, , , , , , , et al. Successful use of chronic epoprostenol as a bridge to liver transplantation in severe portopulmonary hypertension. Transplantation 1998; 65:457–459. MEDLINE
- 24

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