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References

  • 1
    Doong SL, Tsai CH, Schinazi RF, Liotta DC, Cheng YC. Inhibition of the replication of hepatitis B virus in vitro by 2′, 3′-dideoxy-3′thiacytidine and related analogues. Proc Natl Acad Sci U S A 1991; 88:84958499. MEDLINE
  • 2
    Dienstag JL, Perrillo RP, Schiff ER, Bartholomew M, Vicary C, Rubin M. A preliminary trial of lamivudine for chronic hepatitis B infection. N Engl J Med 1995; 333:16571661. MEDLINE
  • 3
    Nevens F, Main J, Honkoop P, Tyrrell DL, Barber J, Sullivan MT, Fevery J, et al. Lamivudine therapy for chronic hepatitis B: a six-month randomized dose-ranging study. Gastroenterology 1997; 113:12581263. MEDLINE
  • 4
    Boni C, Bertoletti A, Penna A, Cavalli A, Pilli M, Urbani S, Scognamiglio P, et al. Lamivudine treatment can restore T cell responsiveness in chronic hepatitis B. J Clin Invest 1998; 102:18. MEDLINE
  • 5
    Lai CL, Chien RN, Leung NWY, Chang TT, Guan R, Tai DI, Ng KY, et al. A one year trial of lamivudine for chronic hepatitis B. N Engl J Med 1998; 339:6168. MEDLINE
  • 6
    Zoulim F, Trepo C. Drug therapy for chronic hepatitis B: antiviral efficacy and influence of hepatitis B virus polymerase mutations on the outcome of therapy. J Hepatol 1998; 29:151168. MEDLINE
  • 7
    Wong DKH, Cheung AM, O'Rourke K, Naylor CD, Detsky AS, Heathcote J. Effect of alpha-interferon treatment in patients with hepatitis B e antigen-positive chronic hepatitis B; a meta-analysis. Ann Intern Med 1993; 119:312323. MEDLINE
  • 8
    Liaw YF. Current trends in therapy for chronic viral hepatitis. J Gastroenterol Hepatol 1997; 12:S346S353. MEDLINE
  • 9
    Lok ASF, Chang MG, Watson G, Ayola B. Predictive value of aminotransferase and hepatitis B virus DNA levels on response to interferon therapy for chronic hepatitis B. J Viral Hepat 1998; 5:171178. MEDLINE
  • 10
    Liaw YF, Tsai SL. Pathogenesis and clinical significance of acute exacerbations and remissions in patients with chronic hepatitis B virus infection. Viral Hep Rev 1997; 3:143154.
  • 11
    Wu TT, Coates L, Aldrich CE, Summers J, Mason WS. In hepatocytes infected with duck hepatitis B virus, the template for viral RNA synthesis is amplified by an intracellular pathway. Virology 1990; 175:255261. MEDLINE
  • 12
    Fourel I, Cullen J, Saputelli J, Aldrich C, Schaffer P, Averett D, Pugh J, et al. Evidence that hepatocyte turnover is required for rapid clearance of duck hepatitis B virus during antiviral therapy of chronically infected ducks. J Virol 1994; 68:83218330. MEDLINE
  • 13
    Mason WS, Cullen J, Moraleda G, Saputelli J, Aldrich CE, Miller DS, Tennant B, et al. Lamivudine therapy of WHV-infected woodchucks. Virology 1998; 245:1832. MEDLINE
  • 14
    Schiff E, Cianciara J, Kowdley K, Norkrans G, Perillo R, Tong M, Crowther L, et al. Durability of HbeAg seroconversion after lamivudine monotherapy in controlled phase II and III trials [Abstr]. Hepatology 28(Suppl): 1832.
  • 15
    Liaw YF, Chien RN, Yeh CT, Tsai SL, Chu CM. Acute exacerbation and hepatitis B virus clearance after emergence of YMDD motif mutation during lamivudine therapy. Hepatology 1999; 30 (in press).
  • 16
    Liaw YF, Lai CL, Leung NWY, Chang TT, Guan R, Tai DI, Ng KY, et al. Two year lamivudine therapy in chronic hepatitis B infection: results of a placebo controlled multicenter study in Asia [Abstract]. Gastroenterology 1998; 114:A1289.