Original Article

You have full text access to this OnlineOpen article

Transjugular intrahepatic portosystemic shunt compared with endoscopic treatment for prevention of variceal rebleeding: A meta-analysis

  1. George V. Papatheodoridis1,
  2. John Goulis1,
  3. Gioacchino Leandro2,
  4. David Patch F.R.C.P.1,*,
  5. Andrew K. Burroughs1

Article first published online: 30 DEC 2003

DOI: 10.1002/hep.510300316

Issue

Hepatology

Hepatology

Volume 30, Issue 3, pages 612–622, September 1999

Additional Information

How to Cite

Papatheodoridis, G. V., Goulis, J., Leandro, G., Patch, D. and Burroughs, A. K. (1999), Transjugular intrahepatic portosystemic shunt compared with endoscopic treatment for prevention of variceal rebleeding: A meta-analysis. Hepatology, 30: 612–622. doi: 10.1002/hep.510300316

Author Information

  1. 1

    Liver Transplantation & Hepatobiliary Medicine, Royal Free Hospital, London, UK

  2. 2

    Ospedale Gastroenterologico “S. De Bellis,” IRCCS, Castellana Grotte, Italy

*Liver Transplantation & Hepatobiliary Medicine, Royal Free Hospital, Pond Street, London NW3 2QG, UK. Fax: 00 (44) 171-794-4688

Publication History

  1. Issue published online: 30 DEC 2003
  2. Article first published online: 30 DEC 2003
  3. Manuscript Accepted: 2 JUN 1999
  4. Manuscript Received: 25 MAR 1999

SEARCH

SEARCH BY CITATION

ARTICLE TOOLS

Get PDF (136K)

References

  • 1
    D'Amico G, Morabito A, Pagliaro L, Marubini E, Caltagirone M, Filippazzo G, Gatto G, et al. Survival and prognostic indicators in compensated and decompensated cirrhosis. Dig Dis Sci 1986; 31:468–475. MEDLINE
  • 2
    Pagliaro L, Burroughs AK, Sorensen TIA, Lebrec D, Morabito A, D'Amico G, Tine F. Therapeutic controversies and randomized controlled trials (RCTs): prevention of bleeding and rebleeding in cirrhosis. Gastroenterol Intern 1989; 2:71–84.
  • 3
    D'Amico G, Pagliaro L, Bosch J. The treatment of portal hypertension: a meta-analytic review. Hepatology 1995; 22:332–354. MEDLINE
    Direct Link:
  • 4
    Stiegmann GV, Goff JS, Michaletz-Onody PA, Korula J, Lieberman D, Saeed ZA, Reveille RM, et al. Endoscopic sclerotherapy as compared with endoscopic ligation for bleeding esophageal varices. N Engl J Med 1992; 326:1527–1521. MEDLINE
  • 5
    Laine L, Cook D. Endoscopic ligation compared with sclerotherapy for treatment of esophageal variceal bleeding. A meta-analysis. Ann Intern Med 1995; 123:280–287. MEDLINE
  • 6
    Saeed ZA, Stiegmann GV, Ramirez FC, Reveille RM, Goff JS, Hepps KS, Cole RA. Endoscopic variceal ligation is superior to combined ligation and sclerotherapy for esophageal varices: a multicenter prospective randomized trial. Hepatology 1997; 25:71–74. MEDLINE
    Direct Link:
  • 7
    Laine L, Stein C, Sharma V. Randomized comparison of ligation versus ligation plus sclerotherapy in patients with bleeding esophageal varices. Gastroenterology 1996; 110:529–533. MEDLINE
  • 8
    Rossle M, Haag K, Ochs A, Sellinger M, Noldge G, Perarnau JM, Berger E, et al. The transjugular intrahepatic portosystemic stent-shunt procedure for variceal bleeding. N Engl J Med 1994; 330:165–171. MEDLINE
  • 9
    Conn HO. The transjugular intrahepatic portal-systemic shunts: the state of the art. Hepatology 1993; 17:148–158. MEDLINE
    Direct Link:
  • 10
    Shiffman ML, Jeffers L, Hoofnagle JH, Tralka TS. The role of transjugular intrahepatic portosystemic shunt for treatment of portal hypertension and its complications: a conference sponsored by the National Digestive Diseases Advisory Board. Hepatology 1995; 22:1591–1597. MEDLINE
    Direct Link:
  • 11
    Grace ND, Groszmann R, Garcia-Tsao G, Burroughs AK, Pagliaro L, Makuch RW, Bosch J, et al. Portal hypertension and variceal bleeding: an AASLD single topic symposium. Hepatology 1998; 28:868–880. MEDLINE
    Direct Link:
  • 12
    La Berge JM, Ring EJ, Gordon RL, Lake JR, Dherty MM, Somberg KA, Roberts JP, et al. Creation of transjugular intrahepatic portosystemic shunt with the wall stent endoprosthesis: results in 100 patients. Radiology 1993; 187:413–420. MEDLINE
  • 13
    Sanyal AJ, Freedman AM, Luketic VA, Purdum PP, Schiffman ML, Cole PE, Tisnado J, et al. Transjugular intrahepatic portosystemic shunts compared with endoscopic sclerotherapy for the prevention of recurrent variceal hemorrhage. A randomized, controlled trial. Ann Intern Med 1997; 126:849–857. MEDLINE
  • 14
    Cabrera J, Maynar M, Granados R, Gorriz E, Reyes R, Pulido-Duque JM, Rodriguez SR, et al. Transjugular intrahepatic portosystemic shunt versus sclerotherapy in the elective treatment of variceal hemorrhage. Gastroenterology 1996; 110:832–839. MEDLINE
  • 15
    Cello JP, Ring EJ, Olcott EW, Koch J, Gordon R, Sandhu J, Morgan DR, et al. Endoscopic sclerotherapy compared with percutaneous transjugular intrahepatic portosystemic shunt after initial sclerotherapy in patients with acute variceal hemorrhage. Ann Intern Med 1997; 126:858–865. MEDLINE
  • 16
    Garcia-Villareal L, Martinez-Lagares F, Siebra A, Guevara C, Marrero JM, Jimenez E, Monescillo A, et al. Transjugular intrahepatic portosystemic shunt versus endoscopic sclerotherapy for the prevention of variceal rebleeding after recent variceal hemorrhage. Hepatology 1999; 29:27–32. MEDLINE
    Direct Link:
  • 17
    Nicolucci A, Grilli R, Alexanian AA, Apollone G, Torri V, Liberati A. Quality evolution and clinical implications of randomized clinical trials on the treatment of lung cancer—a lost opportunity for meta-analysis. JAMA 1989; 262:2101–2107. MEDLINE
  • 18
    De Franchis R. Developing consensus in portal hypertension. J Hepatol 1996; 25:390–394. MEDLINE
  • 19
    Robbins J, Brenslow N, Greenland S. Estimators of the Mantel-Haenszel variance consistent in both sparse data and large strata limiting models. Biometrics 1986; 42:311–323. MEDLINE
  • 20
    Der Simonian R, Laird N. Meta-analysis in clinical trials. Controlled Clin Trials 1986; 7:177–188. MEDLINE
  • 21
    LaBerge JM, Somberg KA, Lake JR, Gordon RL, Kerlan RK, Ascher NL, Roberts JP, et al. Two-year outcome following transjugular intrahepatic portosystemic shunt for variceal bleeding: results in 90 patients. Gastroenterology 1995; 108:1143–1151. MEDLINE
  • 22
    Di Mario F, Battaglia G, Leandro G, Grasso G, Vianello F, Vigneri S. Short-term treatment of gastric ulcer. A meta-analytical evaluation of blind trials. Dig Dis Sci 1996; 41:1108–1131. MEDLINE
  • 23
    Rossle M, Deibert P, Haag K, Ochs A, Olschewski M, Siegerstetter V, Hauenstein KH, et al. Randomised trial of transjugular-intrahepatic-portosystemic shunt versus endoscopy plus propranolol for prevention of variceal rebleeding. Lancet 1997; 349:1043–1049. MEDLINE
  • 24
    Sauer P, Theilmann L, Stremmel W, Benz C, Richter GM, Stiehl A. Transjugular intrahepatic portosystemic stent shunt versus sclerotherapy plus propranolol for variceal rebleeding. Gastroenterology 1997; 113:1623–1631. MEDLINE
  • 25
    Jalan R, Forrest EH, Stanley AJ, Redhead DN, Forbes J, Dillon JF, MacGilchrist AJ, et al. A randomized trial comparing transjugular intrahepatic portosystemic stent-shunt with variceal band ligation in the prevention of rebleeding from esophageal varices. Hepatology 1997; 26:1115–1122. MEDLINE
  • 26
    Merli M, Salerno F, Riggio O, De Franchis R, Fiaccadori F, Meddi P, Primignani M, et al. Transjugular intrahepatic portosystemic shunt versus endoscopic sclerotherapy for the prevention of variceal bleeding in cirrhosis: a randomized multicenter trial. Gruppo Italiano Studio TIPS (G.I.S.T.). Hepatology 1998; 27:48–53. MEDLINE
    Direct Link:
  • 27
    Groupe d'Etude des Anastomoses Intra-Hepatiques (Toulouse BLNCPF). TIPS vs sclerotherapy+propranolol in the prevention of variceal rebleeding: preliminary results of a multicenter randomized trial [Abstract]. Hepatology 1995; 22(Suppl):299A.
  • 28
    Pomier-Layrargues G, Dufresne MP, Bui B, Lambert J, Fenyves D, Willems B, Marleau D, et al. TIPS versus endoscopic variceal ligation in the prevention of variceal rebleeding in cirrhotic patients: a comparative randomized clinical trial (interim analysis) [Abstract]. Hepatology 1997; 26(Suppl):137A.
  • 29
    Sauer P, Benz C, Theilmann L, Richter G, Stremmel W, Stiehl A. Transjugular intrahepatic portosystemic stent shunt (TIPS) vs. endoscopic banding in the prevention of variceal rebleeding: final results of a randomized study [Abstract]. Gastroenterology 1998; 114:A1334.
  • 30
    Grace ND, Conn HO, Resnick RH, Groszmann RJ, Atterbury CE, Wright SC, Gusberg RJ, et al. Distal splenorenal vs. portal-systemic shunts after hemorrhage from varices: a randomized controlled trial. Hepatology 1988; 8:1475–1481. MEDLINE
    Direct Link:
  • 31
    Spina GP, Henderson JM, Rikkers LF, Teres J, Burroughs AK, Conn HO, Pagliaro L, et al. Distal splenorenal shunt versus endoscopic sclerotherapy in the prevention of variceal rebleeding—a metaanalysis of 4 randomized clinical-trials. J Hepatol 1992; 16:338–345. MEDLINE
  • 32
    Barton RE, Rosch J, Saxon RR, Lakin PC, Petersen BD, Keller FS. TIPS: short and long-term results: a survey of 1750 patients. Semin Intervent Radiol 1995; 12:364–367.
  • 33
    Ferguson J, Jalan R, Redhead DN, Hayes P, Allan PA. The role of Duplex Doppler in monitoring shunt function following transjugular intrahepatic stent shunt. Br J Radiol 1995; 68:587–589. MEDLINE
  • 34
    Graham DY, Smith JL. The course of patients after variceal hemorrhage. Gastroenterology 1981; 80:800–809. MEDLINE
  • 35
    Pagliaro L, D'Amico G, Pasta L, Politi F, Vizzini G, Traina M, Madonia S, et al. Portal hypertension in cirrhosis: natural history. In: BoschJ, GroszmannR, eds. Portal Hypertension: Pathophysiology and Treatment. Cambridge, MA: Blackwell Scientific, 1994; 72–92.
  • 36
    Jalan R, Redhead DN, Hayes PC. Transjugular intrahepatic portasystemic stent-shunt in the treatment of variceal hemorrhage. Br J Surg 1995; 82:1158–1164. MEDLINE
    Direct Link:
Get PDF (136K)