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Hepatology

Cover image for Hepatology

December 2005

Volume 42, Issue 6

Pages 1241–1471

  1. Hepatology Highlights

    1. Top of page
    2. Hepatology Highlights
    3. This Month From The NIH
    4. 2005 AASLD Awardees
    5. Editorial
    6. Science Frontier
    7. Liver Biology and Pathobiology
    8. Liver Biology and Pathobiology
    9. Liver Failure and Liver Disease
    10. Viral Hepatitis
    11. Hepatology Elsewhere
    12. Correspondence
    13. Landmarks
    14. Corrections
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      Hepatology highlights (pages 1241–1242)

      Elwyn Elias

      Version of Record online: 29 NOV 2005 | DOI: 10.1002/hep.20992

  2. This Month From The NIH

    1. Top of page
    2. Hepatology Highlights
    3. This Month From The NIH
    4. 2005 AASLD Awardees
    5. Editorial
    6. Science Frontier
    7. Liver Biology and Pathobiology
    8. Liver Biology and Pathobiology
    9. Liver Failure and Liver Disease
    10. Viral Hepatitis
    11. Hepatology Elsewhere
    12. Correspondence
    13. Landmarks
    14. Corrections
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      Research opportunities on alcohol and liver damage (page 1243)

      Samir Zakhari and Jay H. Hoofnagle

      Version of Record online: 29 NOV 2005 | DOI: 10.1002/hep.20972

  3. 2005 AASLD Awardees

    1. Top of page
    2. Hepatology Highlights
    3. This Month From The NIH
    4. 2005 AASLD Awardees
    5. Editorial
    6. Science Frontier
    7. Liver Biology and Pathobiology
    8. Liver Biology and Pathobiology
    9. Liver Failure and Liver Disease
    10. Viral Hepatitis
    11. Hepatology Elsewhere
    12. Correspondence
    13. Landmarks
    14. Corrections
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    2. You have free access to this content
  4. Editorial

    1. Top of page
    2. Hepatology Highlights
    3. This Month From The NIH
    4. 2005 AASLD Awardees
    5. Editorial
    6. Science Frontier
    7. Liver Biology and Pathobiology
    8. Liver Biology and Pathobiology
    9. Liver Failure and Liver Disease
    10. Viral Hepatitis
    11. Hepatology Elsewhere
    12. Correspondence
    13. Landmarks
    14. Corrections
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      Microcirculation of the aging liver: Is getting old like having cirrhosis? (pages 1248–1251)

      Pierre-Michel Huet and Jean-Pierre Villeneuve

      Version of Record online: 29 NOV 2005 | DOI: 10.1002/hep.20991

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    5. You have free access to this content
  5. Science Frontier

    1. Top of page
    2. Hepatology Highlights
    3. This Month From The NIH
    4. 2005 AASLD Awardees
    5. Editorial
    6. Science Frontier
    7. Liver Biology and Pathobiology
    8. Liver Biology and Pathobiology
    9. Liver Failure and Liver Disease
    10. Viral Hepatitis
    11. Hepatology Elsewhere
    12. Correspondence
    13. Landmarks
    14. Corrections
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  6. Liver Biology and Pathobiology

    1. Top of page
    2. Hepatology Highlights
    3. This Month From The NIH
    4. 2005 AASLD Awardees
    5. Editorial
    6. Science Frontier
    7. Liver Biology and Pathobiology
    8. Liver Biology and Pathobiology
    9. Liver Failure and Liver Disease
    10. Viral Hepatitis
    11. Hepatology Elsewhere
    12. Correspondence
    13. Landmarks
    14. Corrections
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      OSTα-OSTβ: A major basolateral bile acid and steroid transporter in human intestinal, renal, and biliary epithelia (pages 1270–1279)

      Nazzareno Ballatori, Whitney V. Christian, Jin Young Lee, Paul A. Dawson, Carol J. Soroka, James L. Boyer, Michael S. Madejczyk and Na Li

      Version of Record online: 29 NOV 2005 | DOI: 10.1002/hep.20961

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      Alcohol increases tumor necrosis factor α and decreases nuclear factor-κb to activate hepatic apoptosis in genetically obese mice (pages 1280–1290)

      Marie-Anne Robin, Christine Demeilliers, Angéla Sutton, Valérie Paradis, Caroline Maisonneuve, Sylvie Dubois, Odile Poirel, Philippe Lettéron, Dominique Pessayre and Bernard Fromenty

      Version of Record online: 29 NOV 2005 | DOI: 10.1002/hep.20949

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      Conjugated bile acids promote ERK1/2 and AKT activation via a pertussis toxin–sensitive mechanism in murine and human hepatocytes (pages 1291–1299)

      Paul Dent, Youwen Fang, Seema Gupta, Elaine Studer, Clint Mitchell, Sarah Spiegel and Philip B. Hylemon

      Version of Record online: 29 NOV 2005 | DOI: 10.1002/hep.20942

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      A novel system for efficient gene transfer into primary human hepatocytes via cell-permeable hepatitis B virus–like particle (pages 1300–1309)

      Boerries Brandenburg, Lars Stockl, Cindy Gutzeit, Martin Roos, Joachim Lupberger, Ruth Schwartlander, Hans Gelderblom, Igor M. Sauer, Peter Hans Hofschneider and Eberhard Hildt

      Version of Record online: 29 NOV 2005 | DOI: 10.1002/hep.20950

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      Role of HSP90, CDC37, and CRM1 as modulators of P16INK4A activity in rat liver carcinogenesis and human liver cancer (pages 1310–1319)

      Rosa M. Pascale, Maria M. Simile, Diego F. Calvisi, Maddalena Frau, Maria R. Muroni, Maria A. Seddaiu, Lucia Daino, Maria D. Muntoni, Maria R. De Miglio, Snorri S. Thorgeirsson and Francesco Feo

      Version of Record online: 29 NOV 2005 | DOI: 10.1002/hep.20962

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      Roles of AKT and sphingosine kinase in the antiapoptotic effects of bile duct ligation in mouse liver (pages 1320–1328)

      Yosuke Osawa, Yusuf A. Hannun, Richard L. Proia and David A. Brenner

      Version of Record online: 29 NOV 2005 | DOI: 10.1002/hep.20967

  7. Liver Biology and Pathobiology

    1. Top of page
    2. Hepatology Highlights
    3. This Month From The NIH
    4. 2005 AASLD Awardees
    5. Editorial
    6. Science Frontier
    7. Liver Biology and Pathobiology
    8. Liver Biology and Pathobiology
    9. Liver Failure and Liver Disease
    10. Viral Hepatitis
    11. Hepatology Elsewhere
    12. Correspondence
    13. Landmarks
    14. Corrections
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      Interleukin 6 upregulates myeloid cell leukemia-1 expression through a STAT3 pathway in cholangiocarcinoma cells (pages 1329–1338)

      Hajime Isomoto, Shogo Kobayashi, Nathan W. Werneburg, Steve F. Bronk, Maria Eugenia Guicciardi, David A. Frank and Gregory J. Gores

      Version of Record online: 29 NOV 2005 | DOI: 10.1002/hep.20966

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      Upregulation of proinflammatory and proangiogenic cytokines by leptin in human hepatic stellate cells (pages 1339–1348)

      Sara Aleffi, Ilaria Petrai, Cristiana Bertolani, Maurizio Parola, Sebastiano Colombatto, Erica Novo, Francesco Vizzutti, Frank A. Anania, Stefano Milani, Krista Rombouts, Giacomo Laffi, Massimo Pinzani and Fabio Marra

      Version of Record online: 29 NOV 2005 | DOI: 10.1002/hep.20965

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      Age-related changes in the hepatic sinusoidal endothelium impede lipoprotein transfer in the rat (pages 1349–1354)

      Sarah N. Hilmer, Victoria C. Cogger, Robin Fraser, Allan J. McLean, David Sullivan and David G. Le Couteur

      Version of Record online: 29 NOV 2005 | DOI: 10.1002/hep.20937

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  8. Liver Failure and Liver Disease

    1. Top of page
    2. Hepatology Highlights
    3. This Month From The NIH
    4. 2005 AASLD Awardees
    5. Editorial
    6. Science Frontier
    7. Liver Biology and Pathobiology
    8. Liver Biology and Pathobiology
    9. Liver Failure and Liver Disease
    10. Viral Hepatitis
    11. Hepatology Elsewhere
    12. Correspondence
    13. Landmarks
    14. Corrections
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      Acetaminophen-induced acute liver failure: Results of a United States multicenter, prospective study (pages 1364–1372)

      Anne M. Larson, Julie Polson, Robert J. Fontana, Timothy J. Davern, Ezmina Lalani, Linda S. Hynan, Joan S. Reisch, Frank V. Schiødt, George Ostapowicz, A. Obaid Shakil and William M. Lee

      Version of Record online: 29 NOV 2005 | DOI: 10.1002/hep.20948

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      A novel panel of blood markers to assess the degree of liver fibrosis (pages 1373–1381)

      Paul Calès, Frédéric Oberti, Sophie Michalak, Isabelle Hubert-Fouchard, Marie-Christine Rousselet, Anselme Konaté, Yves Gallois, Catherine Ternisien, Alain Chevailler and Françoise Lunel

      Version of Record online: 29 NOV 2005 | DOI: 10.1002/hep.20935

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      A role for asymmetric dimethylarginine in the pathophysiology of portal hypertension in rats with biliary cirrhosis (pages 1382–1390)

      Wim Laleman, Anita Omasta, Marc Van de Casteele, Marcel Zeegers, Ingrid Vander Elst, Lien Van Landeghem, Tamara Severi, Jos van Pelt, Tania Roskams, Johan Fevery and Frederik Nevens

      Version of Record online: 29 NOV 2005 | DOI: 10.1002/hep.20968

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      Novel biotransformation and physiological properties of norursodeoxycholic acid in humans (pages 1391–1398)

      Alan F. Hofmann, Salam F. Zakko, Marco Lira, Carlo Clerici, Lee R. Hagey, K. Karel Lambert, Joseph H. Steinbach, Claudio D. Schteingart, Peter Olinga and Geny M. M. Groothuis

      Version of Record online: 29 NOV 2005 | DOI: 10.1002/hep.20943

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      Intrahepatic cholestasis of pregnancy: A randomized controlled trial comparing dexamethasone and ursodeoxycholic acid (pages 1399–1405)

      Anna Glantz, Hanns-Ulrich Marschall, Frank Lammert and Lars-Åke Mattsson

      Version of Record online: 29 NOV 2005 | DOI: 10.1002/hep.20952

  9. Viral Hepatitis

    1. Top of page
    2. Hepatology Highlights
    3. This Month From The NIH
    4. 2005 AASLD Awardees
    5. Editorial
    6. Science Frontier
    7. Liver Biology and Pathobiology
    8. Liver Biology and Pathobiology
    9. Liver Failure and Liver Disease
    10. Viral Hepatitis
    11. Hepatology Elsewhere
    12. Correspondence
    13. Landmarks
    14. Corrections
    1. You have free access to this content
      Trends in health care resource use for hepatitis C virus infection in the United States (pages 1406–1413)

      William C. Grant, Ravi R. Jhaveri, John G. McHutchison, Kevin A. Schulman and Teresa L. Kauf

      Version of Record online: 29 NOV 2005 | DOI: 10.1002/hep.20941

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      Adefovir rapidly suppresses hepatitis B in HBeAg-negative patients developing genotypic resistance to lamivudine (pages 1414–1419)

      Pietro Lampertico, Mauro Viganò, Elena Manenti, Massimo Iavarone, Giovanna Lunghi and Massimo Colombo

      Version of Record online: 29 NOV 2005 | DOI: 10.1002/hep.20939

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      Accelerated hepatitis C virus kinetics but similar survival rates in recipients of liver grafts from living versus deceased donors (pages 1420–1428)

      Thomas D. Schiano, Julio A. Gutierrez, Jose L. Walewski, M. Isabel Fiel, Bonnie Cheng, Henry Bodenheimer Jr., Swan N. Thung, Raymond T. Chung, Myron E. Schwartz, Carol Bodian and Andrea D. Branch

      Version of Record online: 29 NOV 2005 | DOI: 10.1002/hep.20947

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      Sustained E2 antibody response correlates with reduced peak viremia after hepatitis C virus infection in the chimpanzee (pages 1429–1436)

      Jin-Won Youn, Su-Hyung Park, Dimitri Lavillette, Francois-Loic Cosset, Se-Hwan Yang, Chang Geun Lee, Hyun-Tak Jin, Chang-Min Kim, Mohamed Tarek M. Shata, Dong-Hun Lee, Wolfram Pfahler, Alfred M. Prince and Young Chul Sung

      Version of Record online: 29 NOV 2005 | DOI: 10.1002/hep.20934

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      Prediction of significant fibrosis in HBeAg-positive patients with chronic hepatitis B by a noninvasive model (pages 1437–1445)

      Min-De Zeng, Lun-Gen Lu, Yi-Min Mao, De-Kai Qiu, Ji-Qiang Li, Mo-Bin Wan, Cheng-Wei Chen, Ji-Yao Wang, Xiong Cai, Chun-Fang Gao and Xia-Qiu Zhou

      Version of Record online: 29 NOV 2005 | DOI: 10.1002/hep.20960

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      Hepatitis C virus load and survival among injection drug users in the United States (pages 1446–1452)

      Michie Hisada, Nilanjan Chatterjee, Zeynep Kalaylioglu, Robert J. Battjes and James J. Goedert

      Version of Record online: 29 NOV 2005 | DOI: 10.1002/hep.20938

  10. Hepatology Elsewhere

    1. Top of page
    2. Hepatology Highlights
    3. This Month From The NIH
    4. 2005 AASLD Awardees
    5. Editorial
    6. Science Frontier
    7. Liver Biology and Pathobiology
    8. Liver Biology and Pathobiology
    9. Liver Failure and Liver Disease
    10. Viral Hepatitis
    11. Hepatology Elsewhere
    12. Correspondence
    13. Landmarks
    14. Corrections
    1. You have free access to this content
      Hepatitis B virus cccDNA clearance: Killing for curing? (pages 1453–1455)

      Maura Dandri and Jorg Petersen

      Version of Record online: 29 NOV 2005 | DOI: 10.1002/hep.20976

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      Treating hepatitis C: Can you teach old dogs new tricks? (pages 1455–1458)

      Charles M. Rice and Shihyun You

      Version of Record online: 29 NOV 2005 | DOI: 10.1002/hep.20975

  11. Correspondence

    1. Top of page
    2. Hepatology Highlights
    3. This Month From The NIH
    4. 2005 AASLD Awardees
    5. Editorial
    6. Science Frontier
    7. Liver Biology and Pathobiology
    8. Liver Biology and Pathobiology
    9. Liver Failure and Liver Disease
    10. Viral Hepatitis
    11. Hepatology Elsewhere
    12. Correspondence
    13. Landmarks
    14. Corrections
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      Reply: (pages 1459–1460)

      Thomas Berg

      Version of Record online: 29 NOV 2005 | DOI: 10.1002/hep.20977

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      Spectrum of NAFLD and diagnostic implications of the proposed new normal range for serum ALT in obese women (pages 1460–1461)

      Daniele Prati, Agostino Colli, Dario Conte and Massimo Colombo

      Version of Record online: 29 NOV 2005 | DOI: 10.1002/hep.20964

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      Reply: (page 1461)

      Gary A. Abrams, Ronald H. Clements, Audrey J. Lazenby and Sachin S. Kunde

      Version of Record online: 29 NOV 2005 | DOI: 10.1002/hep.20978

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      It takes more than one—Is a single UGT polymorphism enough to bother detoxification? (page 1462)

      Christoph G. Dietrich and Andreas Geier

      Version of Record online: 29 NOV 2005 | DOI: 10.1002/hep.20963

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      Reply: (page 1463)

      Chantal Guillemette and Hugo Girard

      Version of Record online: 29 NOV 2005 | DOI: 10.1002/hep.20979

  12. Landmarks

    1. Top of page
    2. Hepatology Highlights
    3. This Month From The NIH
    4. 2005 AASLD Awardees
    5. Editorial
    6. Science Frontier
    7. Liver Biology and Pathobiology
    8. Liver Biology and Pathobiology
    9. Liver Failure and Liver Disease
    10. Viral Hepatitis
    11. Hepatology Elsewhere
    12. Correspondence
    13. Landmarks
    14. Corrections
    1. You have free access to this content
      First do no harm (pages 1464–1470)

      Adrian Reuben

      Version of Record online: 29 NOV 2005 | DOI: 10.1002/hep.20995

  13. Corrections

    1. Top of page
    2. Hepatology Highlights
    3. This Month From The NIH
    4. 2005 AASLD Awardees
    5. Editorial
    6. Science Frontier
    7. Liver Biology and Pathobiology
    8. Liver Biology and Pathobiology
    9. Liver Failure and Liver Disease
    10. Viral Hepatitis
    11. Hepatology Elsewhere
    12. Correspondence
    13. Landmarks
    14. Corrections
    1. You have free access to this content
      Corrections (page 1471)

      Version of Record online: 29 NOV 2005 | DOI: 10.1002/hep.21010

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      Corrections (page 1471)

      Version of Record online: 29 NOV 2005 | DOI: 10.1002/hep.21012

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