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Hepatology

Cover image for Vol. 46 Issue 4

October 2007

Volume 46, Issue 4

Pages 953–1316

  1. Editorials

    1. Top of page
    2. Editorials
    3. AASLD Public Policy
    4. Viral Hepatitis
    5. Steatohepatitis/Metabolic Liver Disease
    6. Hepatobiliary Malignancies
    7. Autoimmune, Cholestatic, and Biliary Disease
    8. Liver Injury/Regeneration
    9. Liver Failure/Cirrhosis/Portal Hypertension
    10. Liver Biology/Pathobiology
    11. Reviews
    12. Hepatology Elsewhere
    13. Correspondence
    14. Corrections
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      Clinical expression of hemochromatosis gene (HFE) variants (pages 960–962)

      Oyekoya T. Ayonrinde and John K. Olynyk

      Version of Record online: 25 SEP 2007 | DOI: 10.1002/hep.21957

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  2. AASLD Public Policy

    1. Top of page
    2. Editorials
    3. AASLD Public Policy
    4. Viral Hepatitis
    5. Steatohepatitis/Metabolic Liver Disease
    6. Hepatobiliary Malignancies
    7. Autoimmune, Cholestatic, and Biliary Disease
    8. Liver Injury/Regeneration
    9. Liver Failure/Cirrhosis/Portal Hypertension
    10. Liver Biology/Pathobiology
    11. Reviews
    12. Hepatology Elsewhere
    13. Correspondence
    14. Corrections
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  3. Viral Hepatitis

    1. Top of page
    2. Editorials
    3. AASLD Public Policy
    4. Viral Hepatitis
    5. Steatohepatitis/Metabolic Liver Disease
    6. Hepatobiliary Malignancies
    7. Autoimmune, Cholestatic, and Biliary Disease
    8. Liver Injury/Regeneration
    9. Liver Failure/Cirrhosis/Portal Hypertension
    10. Liver Biology/Pathobiology
    11. Reviews
    12. Hepatology Elsewhere
    13. Correspondence
    14. Corrections
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      Peginterferon alfa-2b and weight-based or flat-dose ribavirin in chronic hepatitis C patients: A randomized trial (pages 971–981)

      Ira M. Jacobson, Robert S. Brown Jr, Bradley Freilich, Nezam Afdhal, Paul Y. Kwo, John Santoro, Scott Becker, Adil E. Wakil, David Pound, Eliot Godofsky, Robert Strauss, David Bernstein, Steven Flamm, Mary Pat Pauly, Pabak Mukhopadhyay, Louis H. Griffel and Clifford A. Brass

      Version of Record online: 25 SEP 2007 | DOI: 10.1002/hep.21932

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      Impact of weight-based ribavirin with peginterferon alfa-2b in african americans with hepatitis C virus genotype 1 (pages 982–990)

      Ira M. Jacobson, Robert S. Brown Jr, Jonathan McCone, Martin Black, Clive Albert, Michael S. Dragutsky, Firdous A. Siddiqui, Thomas Hargrave, Paul Y. Kwo, Louis Lambiase, Greg W. Galler, Victor Araya, Bradley Freilich, Joann Harvey, Louis H. Griffel and Clifford A. Brass

      Version of Record online: 25 SEP 2007 | DOI: 10.1002/hep.21670

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      Hepatitis C treatment in “difficult-to-treat” psychiatric patients with pegylated interferon-alpha and ribavirin: Response and psychiatric side effects (pages 991–998)

      Martin Schaefer, Axel Hinzpeter, Ariane Mohmand, Gesa Janssen, Maurice Pich, Markus Schwaiger, Rahul Sarkar, Astrid Friebe, Andreas Heinz, Michael Kluschke, Marlene Ziemer, Juri Gutsche, Viola Weich, Juliane Halangk and Thomas Berg

      Version of Record online: 1 AUG 2007 | DOI: 10.1002/hep.21791

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      Lack of response to exogenous interferon-α in the liver of chimpanzees chronically infected with hepatitis C virus (pages 999–1008)

      Robert E. Lanford, Bernadette Guerra, Catherine B. Bigger, Helen Lee, Deborah Chavez and Kathleen M. Brasky

      Version of Record online: 1 AUG 2007 | DOI: 10.1002/hep.21776

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      Suppressor of cytokine signaling 3 (SOCS3) expression and hepatitis C virus–related chronic hepatitis: Insulin resistance and response to antiviral therapy (pages 1009–1015)

      Marcello Persico, Mario Capasso, Eliana Persico, Monica Svelto, Roberta Russo, Daniela Spano, Lori Crocè, Vincenzo La Mura, Francesco Moschella, Flora Masutti, Roberto Torella, Claudio Tiribelli and Achille Iolascon

      Version of Record online: 1 AUG 2007 | DOI: 10.1002/hep.21782

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      Effect of the interleukin-6 C174G gene polymorphism on treatment of acute and chronic hepatitis C in human immunodeficiency virus coinfected patients (pages 1016–1025)

      Jacob Nattermann, Martin Vogel, Thomas Berg, Mark Danta, Baumgarten Axel, Christoph Mayr, Raffaele Bruno, Christina Tural, Gerd Klausen, Bonaventura Clotet, Thomas Lutz, Frank Grünhage, Michael Rausch, Hans Dieter Nischalke, Knud Schewe, Bernhard Bienek, Georg Haerter, Tilman Sauerbruch, Juergen K. Rockstroh and Ulrich Spengler

      Version of Record online: 1 AUG 2007 | DOI: 10.1002/hep.21778

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      Sensitivity of hepatitis C virus to cyclosporine A depends on nonstructural proteins NS5A and NS5B (pages 1026–1033)

      Fiona Fernandes, Daniel S. Poole, Spencer Hoover, Rannveig Middleton, Adin-Cristian Andrei, Justin Gerstner and Rob Striker

      Version of Record online: 28 JUN 2007 | DOI: 10.1002/hep.21809

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      Clevudine is highly efficacious in hepatitis B e antigen-negative chronic hepatitis B with durable off-therapy viral suppression (pages 1041–1048)

      Byung Chul Yoo, Ju Hyun Kim, Tae-Hun Kim, Kwang Cheol Koh, Soon-Ho Um, Young Soo Kim, Kwan Sik Lee, Byung Hoon Han, Chae Yoon Chon, Joon-Yeol Han, Soo Hyung Ryu, Haak Cheoul Kim, Kwan Soo Byun, Seong Gyu Hwang, Byung-Ik Kim, Mong Cho, Kwon Yoo, Heon-Ju Lee, Jae Seok Hwang, Yun Soo Kim, Young-Suk Lee, Sung-Kyu Choi, Youn-Jae Lee, Jin-Mo Yang, Joong-Won Park, Myung-Seok Lee, Dae-Ghon Kim, Young-Hwa Chung, Se-Hyun Cho, Jong-Young Choi, Young-Oh Kweon, Heon Young Lee, Sook-Hyang Jeong, Hee-Won Yoo and Hyo-Suk Lee

      Version of Record online: 23 JUL 2007 | DOI: 10.1002/hep.21800

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      Hepatitis B virus DNA prediction rules for hepatitis B e antigen–negative chronic hepatitis B (pages 1057–1070)

      Jordan J. Feld, Melissa Ayers, Dahlia El-Ashry, Tony Mazzulli, Raymond Tellier and E. Jenny Heathcote

      Version of Record online: 25 JUL 2007 | DOI: 10.1002/hep.21811

  4. Steatohepatitis/Metabolic Liver Disease

    1. Top of page
    2. Editorials
    3. AASLD Public Policy
    4. Viral Hepatitis
    5. Steatohepatitis/Metabolic Liver Disease
    6. Hepatobiliary Malignancies
    7. Autoimmune, Cholestatic, and Biliary Disease
    8. Liver Injury/Regeneration
    9. Liver Failure/Cirrhosis/Portal Hypertension
    10. Liver Biology/Pathobiology
    11. Reviews
    12. Hepatology Elsewhere
    13. Correspondence
    14. Corrections
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      Hemochromatosis genotypes and risk of 31 disease endpoints: Meta-analyses including 66,000 cases and 226,000 controls (pages 1071–1080)

      Christina Ellervik, Henrik Birgens, Anne Tybjærg-Hansen and Børge G. Nordestgaard

      Version of Record online: 7 SEP 2007 | DOI: 10.1002/hep.21885

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      A lipidomic analysis of nonalcoholic fatty liver disease (pages 1081–1090)

      Puneet Puri, Rebecca A. Baillie, Michelle M. Wiest, Faridoddin Mirshahi, Jayanta Choudhury, Onpan Cheung, Carol Sargeant, Melissa J. Contos and Arun J. Sanyal

      Version of Record online: 25 JUL 2007 | DOI: 10.1002/hep.21763

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      The impact of fat distribution on the severity of nonalcoholic fatty liver disease and metabolic syndrome (pages 1091–1100)

      Onpan Cheung, Ashwani Kapoor, Puneet Puri, Sakita Sistrun, Velimir A. Luketic, Carol C. Sargeant, Melissa J. Contos, Mitchell L. Shiffman, Richard T. Stravitz, Richard K. Sterling and Arun J. Sanyal

      Version of Record online: 3 JUL 2007 | DOI: 10.1002/hep.21803

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      The effects of 48 weeks of rosiglitazone on hepatocyte mitochondria in human nonalcoholic steatohepatitis (pages 1101–1107)

      Stephen H. Caldwell, James T. Patrie, Elizabeth M. Brunt, Jan A. Redick, Christine A. Davis, Sang H. Park and Brent A. Neuschwander-Tetri

      Version of Record online: 27 JUL 2007 | DOI: 10.1002/hep.21813

  5. Hepatobiliary Malignancies

    1. Top of page
    2. Editorials
    3. AASLD Public Policy
    4. Viral Hepatitis
    5. Steatohepatitis/Metabolic Liver Disease
    6. Hepatobiliary Malignancies
    7. Autoimmune, Cholestatic, and Biliary Disease
    8. Liver Injury/Regeneration
    9. Liver Failure/Cirrhosis/Portal Hypertension
    10. Liver Biology/Pathobiology
    11. Reviews
    12. Hepatology Elsewhere
    13. Correspondence
    14. Corrections
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      Overexpression and role of the ATPase and putative DNA helicase RuvB-like 2 in human hepatocellular carcinoma (pages 1108–1118)

      Benoît Rousseau, Ludovic Ménard, Valérie Haurie, Danièle Taras, Jean-Frédéric Blanc, François Moreau-Gaudry, Philippe Metzler, Michel Hugues, Sandrine Boyault, Sylvie Lemière, Xavier Canron, Pierre Costet, Michael Cole, Charles Balabaud, Paulette Bioulac-Sage, Jessica Zucman-Rossi and Jean Rosenbaum

      Version of Record online: 26 JUL 2007 | DOI: 10.1002/hep.21770

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      Efficacy of a novel histone deacetylase inhibitor in murine models of hepatocellular carcinoma (pages 1119–1130)

      Yen-Shen Lu, Yoko Kashida, Samuel K. Kulp, Yu-Chieh Wang, Dasheng Wang, Jui-Hsiang Hung, Monica Tang, Zhong-Zhe Lin, Te-Jung Chen, Ann-Lii Cheng and Ching-Shih Chen

      Version of Record online: 25 JUL 2007 | DOI: 10.1002/hep.21804

  6. Autoimmune, Cholestatic, and Biliary Disease

    1. Top of page
    2. Editorials
    3. AASLD Public Policy
    4. Viral Hepatitis
    5. Steatohepatitis/Metabolic Liver Disease
    6. Hepatobiliary Malignancies
    7. Autoimmune, Cholestatic, and Biliary Disease
    8. Liver Injury/Regeneration
    9. Liver Failure/Cirrhosis/Portal Hypertension
    10. Liver Biology/Pathobiology
    11. Reviews
    12. Hepatology Elsewhere
    13. Correspondence
    14. Corrections
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      Influence of ursodeoxycholic acid on the mortality and malignancy associated with primary biliary cirrhosis: A population-based cohort study (pages 1131–1137)

      Hannah Jackson, Masoud Solaymani-Dodaran, Tim R. Card, Guruprasad P. Aithal, Richard Logan and Joe West

      Version of Record online: 8 AUG 2007 | DOI: 10.1002/hep.21795

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      Innate immune response to double-stranded RNA in biliary epithelial cells is associated with the pathogenesis of biliary atresia (pages 1146–1154)

      Kenichi Harada, Yasunori Sato, Keita Itatsu, Kumiko Isse, Hiroko Ikeda, Mitsue Yasoshima, Yoh Zen, Akira Matsui and Yasuni Nakanuma

      Version of Record online: 27 JUL 2007 | DOI: 10.1002/hep.21797

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      Differential priming of CD8 and CD4 T-cells in animal models of autoimmune hepatitis and cholangitis (pages 1155–1165)

      Katja Derkow, Christoph Loddenkemper, Justine Mintern, Nils Kruse, Katja Klugewitz, Thomas Berg, Bertram Wiedenmann, Hidde L. Ploegh and Eckart Schott

      Version of Record online: 26 JUL 2007 | DOI: 10.1002/hep.21796

  7. Liver Injury/Regeneration

    1. Top of page
    2. Editorials
    3. AASLD Public Policy
    4. Viral Hepatitis
    5. Steatohepatitis/Metabolic Liver Disease
    6. Hepatobiliary Malignancies
    7. Autoimmune, Cholestatic, and Biliary Disease
    8. Liver Injury/Regeneration
    9. Liver Failure/Cirrhosis/Portal Hypertension
    10. Liver Biology/Pathobiology
    11. Reviews
    12. Hepatology Elsewhere
    13. Correspondence
    14. Corrections
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      Aging in rat causes hepatic hyperresposiveness to interleukin-1β which is mediated by neutral sphingomyelinase-2 (pages 1166–1176)

      Kristina Rutkute, Alexander A. Karakashian, Natalia V. Giltiay, Aneta Dobierzewska and Mariana N. Nikolova-Karakashian

      Version of Record online: 1 AUG 2007 | DOI: 10.1002/hep.21777

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      Role of the coagulation system in acetaminophen-induced hepatotoxicity in mice (pages 1177–1186)

      Patricia E. Ganey, James P. Luyendyk, Sandra W. Newport, Theresa M. Eagle, Jane F. Maddox, Nigel Mackman and Robert A. Roth

      Version of Record online: 25 JUL 2007 | DOI: 10.1002/hep.21779

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      Fibroblast growth factor 10 is critical for liver growth during embryogenesis and controls hepatoblast survival via β-catenin activation (pages 1187–1197)

      Tove Berg, C. Bart Rountree, Lily Lee, Joaquin Estrada, Fréderic G. Sala, Andrea Choe, Jacqueline M. Veltmaat, Stijn De Langhe, Rene Lee, Hide Tsukamoto, Gay M. Crooks, Saverio Bellusci and Kasper S. Wang

      Version of Record online: 1 AUG 2007 | DOI: 10.1002/hep.21814

  8. Liver Failure/Cirrhosis/Portal Hypertension

    1. Top of page
    2. Editorials
    3. AASLD Public Policy
    4. Viral Hepatitis
    5. Steatohepatitis/Metabolic Liver Disease
    6. Hepatobiliary Malignancies
    7. Autoimmune, Cholestatic, and Biliary Disease
    8. Liver Injury/Regeneration
    9. Liver Failure/Cirrhosis/Portal Hypertension
    10. Liver Biology/Pathobiology
    11. Reviews
    12. Hepatology Elsewhere
    13. Correspondence
    14. Corrections
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      Fractures and avascular necrosis before and after orthotopic liver transplantation: Long-term follow-up and predictive factors (pages 1198–1207)

      Maureen M. J. Guichelaar, Jeffrey Schmoll, Michael Malinchoc and J. Eileen Hay

      Version of Record online: 25 JUL 2007 | DOI: 10.1002/hep.21805

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      Mutations in the MPV17 gene are responsible for rapidly progressive liver failure in infancy (pages 1218–1227)

      Lee-Jun C. Wong, Nicola Brunetti-Pierri, Qing Zhang, Nada Yazigi, Kevin E. Bove, Beverly B. Dahms, Michelle A. Puchowicz, Ignacio Gonzalez-Gomez, Eric S. Schmitt, Cavatina K. Truong, Charles L. Hoppel, Ping-Chieh Chou, Jing Wang, Erin E. Baldwin, Darius Adams, Nancy Leslie, Richard G. Boles, Douglas S. Kerr and William J. Craigen

      Version of Record online: 10 AUG 2007 | DOI: 10.1002/hep.21799

  9. Liver Biology/Pathobiology

    1. Top of page
    2. Editorials
    3. AASLD Public Policy
    4. Viral Hepatitis
    5. Steatohepatitis/Metabolic Liver Disease
    6. Hepatobiliary Malignancies
    7. Autoimmune, Cholestatic, and Biliary Disease
    8. Liver Injury/Regeneration
    9. Liver Failure/Cirrhosis/Portal Hypertension
    10. Liver Biology/Pathobiology
    11. Reviews
    12. Hepatology Elsewhere
    13. Correspondence
    14. Corrections
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      Transforming growth factor-β and substrate stiffness regulate portal fibroblast activation in culture (pages 1246–1256)

      Zhaodong Li, Jonathan A. Dranoff, Erick P. Chan, Masayuki Uemura, Jean Sévigny and Rebecca G. Wells

      Version of Record online: 11 JUL 2007 | DOI: 10.1002/hep.21792

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      Profibrogenic transforming growth factor-β/activin receptor–like kinase 5 signaling via connective tissue growth factor expression in hepatocytes (pages 1257–1270)

      Hong-Lei Weng, Loredana Ciuclan, Yan Liu, Jafar Hamzavi, Patricio Godoy, Haristi Gaitantzi, Stefan Kanzler, Rainer Heuchel, Uwe Ueberham, Rolf Gebhardt, Katja Breitkopf and Steven Dooley

      Version of Record online: 26 JUL 2007 | DOI: 10.1002/hep.21806

  10. Reviews

    1. Top of page
    2. Editorials
    3. AASLD Public Policy
    4. Viral Hepatitis
    5. Steatohepatitis/Metabolic Liver Disease
    6. Hepatobiliary Malignancies
    7. Autoimmune, Cholestatic, and Biliary Disease
    8. Liver Injury/Regeneration
    9. Liver Failure/Cirrhosis/Portal Hypertension
    10. Liver Biology/Pathobiology
    11. Reviews
    12. Hepatology Elsewhere
    13. Correspondence
    14. Corrections
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      Altered innate immunity in chronic hepatitis C infection: Cause or effect? (pages 1279–1290)

      Gyongyi Szabo, Serena Chang and Angela Dolganiuc

      Version of Record online: 20 SEP 2007 | DOI: 10.1002/hep.21938

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  11. Hepatology Elsewhere

    1. Top of page
    2. Editorials
    3. AASLD Public Policy
    4. Viral Hepatitis
    5. Steatohepatitis/Metabolic Liver Disease
    6. Hepatobiliary Malignancies
    7. Autoimmune, Cholestatic, and Biliary Disease
    8. Liver Injury/Regeneration
    9. Liver Failure/Cirrhosis/Portal Hypertension
    10. Liver Biology/Pathobiology
    11. Reviews
    12. Hepatology Elsewhere
    13. Correspondence
    14. Corrections
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      Is interleukin-6 a gender-specific risk factor for liver cancer? (pages 1304–1305)

      Leif E. Sander, Christian Trautwein and Christian Liedtke

      Version of Record online: 25 SEP 2007 | DOI: 10.1002/hep.21982

  12. Correspondence

    1. Top of page
    2. Editorials
    3. AASLD Public Policy
    4. Viral Hepatitis
    5. Steatohepatitis/Metabolic Liver Disease
    6. Hepatobiliary Malignancies
    7. Autoimmune, Cholestatic, and Biliary Disease
    8. Liver Injury/Regeneration
    9. Liver Failure/Cirrhosis/Portal Hypertension
    10. Liver Biology/Pathobiology
    11. Reviews
    12. Hepatology Elsewhere
    13. Correspondence
    14. Corrections
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      Reply: (pages 1306–1307)

      Emanuel F. Petricoin and Zobair M. Younossi

      Version of Record online: 25 SEP 2007 | DOI: 10.1002/hep.21955

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      Reply: (pages 1308–1309)

      Thierry Thévenot, Vincent Di Martino and Françoise Lunel-Fabiani

      Version of Record online: 25 SEP 2007 | DOI: 10.1002/hep.21944

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      Atorvastatin and portal pressure (pages 1309–1310)

      Daniel Zamora-Valdés, Misael Uribe and Nahum Méndez-Sánchez

      Version of Record online: 25 SEP 2007 | DOI: 10.1002/hep.21915

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      Reply: (page 1310)

      Jonel Trebicka, Tilman Sauerbruch and Jörg Heller

      Version of Record online: 25 SEP 2007 | DOI: 10.1002/hep.21943

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      Reply: (page 1312)

      Onpan Cheung and Arun J. Sanyal

      Version of Record online: 25 SEP 2007 | DOI: 10.1002/hep.21962

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      Hepatitis delta in Europe: Vanishing or refreshing? (pages 1312–1313)

      Giovanni B. Gaeta, Tommaso Stroffolini, Antonina Smedile, Grazia Niro and Alfonso Mele

      Version of Record online: 25 SEP 2007 | DOI: 10.1002/hep.21816

  13. Corrections

    1. Top of page
    2. Editorials
    3. AASLD Public Policy
    4. Viral Hepatitis
    5. Steatohepatitis/Metabolic Liver Disease
    6. Hepatobiliary Malignancies
    7. Autoimmune, Cholestatic, and Biliary Disease
    8. Liver Injury/Regeneration
    9. Liver Failure/Cirrhosis/Portal Hypertension
    10. Liver Biology/Pathobiology
    11. Reviews
    12. Hepatology Elsewhere
    13. Correspondence
    14. Corrections
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      Correction (pages 1314–1316)

      Version of Record online: 17 AUG 2007 | DOI: 10.1002/hep.21947

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      Corrections (pages 1314–1315)

      Version of Record online: 25 SEP 2007 | DOI: 10.1002/hep.21946

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      Corrections (pages 1315–1316)

      Version of Record online: 25 SEP 2007 | DOI: 10.1002/hep.21948

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