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Hepatology

Cover image for Vol. 46 Issue 5

November 2007

Volume 46, Issue 5

Pages 1317–1670

  1. Editorials

    1. Top of page
    2. Editorials
    3. Viral Hepatitis
    4. Steatohepatitis/Metabolic Liver Disease
    5. Hepatobiliary Malignancies
    6. Autoimmune, Cholestatic and Biliary Disease
    7. Liver Failure/Cirrhosis/Portal Hypertension
    8. Liver Injury/Regeneration
    9. Liver Biology/Pathobiology
    10. Special Article
    11. Reviews
    12. Hepatology Elsewhere
    13. Correspondence
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      TRAILs and tribulation (pages 1320–1322)

      Harmeet Malhi

      Version of Record online: 29 OCT 2007 | DOI: 10.1002/hep.21913

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      Apoptotic cell death takes its toll (pages 1323–1325)

      Natalie J. Torok

      Version of Record online: 29 OCT 2007 | DOI: 10.1002/hep.21968

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  2. Viral Hepatitis

    1. Top of page
    2. Editorials
    3. Viral Hepatitis
    4. Steatohepatitis/Metabolic Liver Disease
    5. Hepatobiliary Malignancies
    6. Autoimmune, Cholestatic and Biliary Disease
    7. Liver Failure/Cirrhosis/Portal Hypertension
    8. Liver Injury/Regeneration
    9. Liver Biology/Pathobiology
    10. Special Article
    11. Reviews
    12. Hepatology Elsewhere
    13. Correspondence
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      The phenotype of hepatitis B virus–specific T cells differ in the liver and blood in chronic hepatitis B virus infection (pages 1332–1340)

      J. Judy Chang, Alexander J. V. Thompson, Kumar Visvanathan, Stephen J. Kent, Paul U. Cameron, Fiona Wightman, Paul Desmond, Stephen A. Locarnini and Sharon R. Lewin

      Version of Record online: 8 OCT 2007 | DOI: 10.1002/hep.21844

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      Phase 1B, randomized, double-blind, dose-escalation trial of CPG 10101 in patients with chronic hepatitis C virus (pages 1341–1349)

      John G. McHutchison, Bruce R. Bacon, Stuart C. Gordon, Eric Lawitz, Mitchell Shiffman, Nezam H. Afdhal, Ira M. Jacobson, Andrew Muir, Mohammed Al-Adhami, Mary L. Morris, Julie A. Lekstrom-Himes, Susan M. Efler and Heather L. Davis

      Version of Record online: 10 OCT 2007 | DOI: 10.1002/hep.21773

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      Amino acid substitutions in the hepatitis C virus core region are the important predictor of hepatocarcinogenesis (pages 1357–1364)

      Norio Akuta, Fumitaka Suzuki, Yusuke Kawamura, Hiromi Yatsuji, Hitomi Sezaki, Yoshiyuki Suzuki, Tetsuya Hosaka, Masahiro Kobayashi, Mariko Kobayashi, Yasuji Arase, Kenji Ikeda and Hiromitsu Kumada

      Version of Record online: 26 JUL 2007 | DOI: 10.1002/hep.21836

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      Features and distribution of CD8 T cells with human leukocyte antigen class I–specific receptor expression in chronic hepatitis C (pages 1375–1386)

      Paula Bonorino, Vincent Leroy, Tania Dufeu-Duchesne, Stefania Tongiani-Dashan, Nathalie Sturm, Martine Pernollet, Eric Vivier, Jean-Pierre Zarski, Patrice N. Marche and Evelyne Jouvin-Marche

      Version of Record online: 1 AUG 2007 | DOI: 10.1002/hep.21850

  3. Steatohepatitis/Metabolic Liver Disease

    1. Top of page
    2. Editorials
    3. Viral Hepatitis
    4. Steatohepatitis/Metabolic Liver Disease
    5. Hepatobiliary Malignancies
    6. Autoimmune, Cholestatic and Biliary Disease
    7. Liver Failure/Cirrhosis/Portal Hypertension
    8. Liver Injury/Regeneration
    9. Liver Biology/Pathobiology
    10. Special Article
    11. Reviews
    12. Hepatology Elsewhere
    13. Correspondence
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      Incidence and natural course of fatty liver in the general population: The Dionysos study (pages 1387–1391)

      Giorgio Bedogni, Lucia Miglioli, Flora Masutti, Anna Castiglione, Lory Saveria Crocè, Claudio Tiribelli and Stefano Bellentani

      Version of Record online: 8 AUG 2007 | DOI: 10.1002/hep.21827

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      Lipid-induced oxidative stress causes steatohepatitis in mice fed an atherogenic diet (pages 1392–1403)

      Naoto Matsuzawa, Toshinari Takamura, Seiichiro Kurita, Hirofumi Misu, Tsuguhito Ota, Hitoshi Ando, Masayoshi Yokoyama, Masao Honda, Yoh Zen, Yasuni Nakanuma, Ken-ichi Miyamoto and Shuichi Kaneko

      Version of Record online: 10 OCT 2007 | DOI: 10.1002/hep.21874

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      Role of αvβ6 integrin in acute biliary fibrosis (pages 1404–1412)

      Bruce Wang, Brian M. Dolinski, Noriko Kikuchi, Diane R. Leone, Marion G. Peters, Paul H. Weinreb, Shelia M. Violette and D. Montgomery Bissell

      Version of Record online: 8 OCT 2007 | DOI: 10.1002/hep.21849

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      Glycine N-methyltransferase−/− mice develop chronic hepatitis and glycogen storage disease in the liver (pages 1413–1425)

      Shih-Ping Liu, Ying-Shiuan Li, Yann-Jang Chen, En-Pei Chiang, Anna Fen-Yau Li, Ying-Hue Lee, Ting-Fen Tsai, Michael Hsiao, Shiu-Feng Hwang and Yi-Ming Arthur Chen

      Version of Record online: 15 OCT 2007 | DOI: 10.1002/hep.21863

  4. Hepatobiliary Malignancies

    1. Top of page
    2. Editorials
    3. Viral Hepatitis
    4. Steatohepatitis/Metabolic Liver Disease
    5. Hepatobiliary Malignancies
    6. Autoimmune, Cholestatic and Biliary Disease
    7. Liver Failure/Cirrhosis/Portal Hypertension
    8. Liver Injury/Regeneration
    9. Liver Biology/Pathobiology
    10. Special Article
    11. Reviews
    12. Hepatology Elsewhere
    13. Correspondence
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      N-glycomic changes in hepatocellular carcinoma patients with liver cirrhosis induced by hepatitis B virus (pages 1426–1435)

      Xue-En Liu, Liesbeth Desmyter, Chun-Fang Gao, Wouter Laroy, Sylviane Dewaele, Valerie Vanhooren, Ling Wang, Hui Zhuang, Nico Callewaert, Claude Libert, Roland Contreras and Cuiying Chen

      Version of Record online: 7 AUG 2007 | DOI: 10.1002/hep.21855

  5. Autoimmune, Cholestatic and Biliary Disease

    1. Top of page
    2. Editorials
    3. Viral Hepatitis
    4. Steatohepatitis/Metabolic Liver Disease
    5. Hepatobiliary Malignancies
    6. Autoimmune, Cholestatic and Biliary Disease
    7. Liver Failure/Cirrhosis/Portal Hypertension
    8. Liver Injury/Regeneration
    9. Liver Biology/Pathobiology
    10. Special Article
    11. Reviews
    12. Hepatology Elsewhere
    13. Correspondence
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      Antimitochondrial antibodies in acute liver failure: Implications for primary biliary cirrhosis (pages 1436–1442)

      Patrick S. C. Leung, Lorenzo Rossaro, Paul A. Davis, Ogyi Park, Atsushi Tanaka, Kentaro Kikuchi, Hiroshi Miyakawa, Gary L. Norman, William Lee, M. Eric Gershwin and Acute Liver Failure Study Group

      Version of Record online: 26 JUL 2007 | DOI: 10.1002/hep.21828

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      Alpha-1 antitrypsin Z protein (PiZ) increases hepatic fibrosis in a murine model of cholestasis (pages 1443–1452)

      Ali Mencin, Ekihiro Seki, Yosuke Osawa, Yuzo Kodama, Samuele De Minicis, Michael Knowles and David A. Brenner

      Version of Record online: 1 AUG 2007 | DOI: 10.1002/hep.21832

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      Efficacy and safety of high-dose pravastatin in hypercholesterolemic patients with well-compensated chronic liver disease: Results of a prospective, randomized, double-blind, placebo-controlled, multicenter trial (pages 1453–1463)

      James H. Lewis, Mary Ellen Mortensen, Steven Zweig, Mary Jean Fusco, Jeffrey R. Medoff, Rene Belder and Pravastatin in Chronic Liver Disease Study Investigators

      Version of Record online: 1 AUG 2007 | DOI: 10.1002/hep.21848

  6. Liver Failure/Cirrhosis/Portal Hypertension

    1. Top of page
    2. Editorials
    3. Viral Hepatitis
    4. Steatohepatitis/Metabolic Liver Disease
    5. Hepatobiliary Malignancies
    6. Autoimmune, Cholestatic and Biliary Disease
    7. Liver Failure/Cirrhosis/Portal Hypertension
    8. Liver Injury/Regeneration
    9. Liver Biology/Pathobiology
    10. Special Article
    11. Reviews
    12. Hepatology Elsewhere
    13. Correspondence
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      Sinusoidal endothelial cell repopulation following ischemia/reperfusion injury in rat liver transplantation (pages 1464–1475)

      Donna Beer Stolz, Mark A. Ross, Atsushi Ikeda, Koji Tomiyama, Takashi Kaizu, David A. Geller and Noriko Murase

      Version of Record online: 10 OCT 2007 | DOI: 10.1002/hep.21887

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      Outcomes of donor evaluation in adult-to-adult living donor liver transplantation (pages 1476–1484)

      James F. Trotter, Karen A. Wisniewski, Norah A. Terrault, James E. Everhart, Milan Kinkhabwala, Robert M. Weinrieb, Jeffrey H. Fair, Robert A. Fisher, Alan J. Koffron, Sammy Saab, Robert M. Merion and A2ALL Study Group

      Version of Record online: 1 AUG 2007 | DOI: 10.1002/hep.21845

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      Decreased white matter lesion volume and improved cognitive function after liver transplantation (pages 1485–1490)

      Alex Rovira, Beatriz Mínguez, F. Xavier Aymerich, Carlos Jacas, Elena Huerga, Juan Córdoba and Juli Alonso

      Version of Record online: 10 OCT 2007 | DOI: 10.1002/hep.21911

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      Survival after liver transplantation: Is racial disparity inevitable? (pages 1491–1497)

      Tae Hoon Lee, Nilay Shah, Rachel A. Pedersen, Walter K. Kremers, Charles B. Rosen, Goran B. Klintmalm and W. Ray Kim

      Version of Record online: 10 OCT 2007 | DOI: 10.1002/hep.21830

  7. Liver Injury/Regeneration

    1. Top of page
    2. Editorials
    3. Viral Hepatitis
    4. Steatohepatitis/Metabolic Liver Disease
    5. Hepatobiliary Malignancies
    6. Autoimmune, Cholestatic and Biliary Disease
    7. Liver Failure/Cirrhosis/Portal Hypertension
    8. Liver Injury/Regeneration
    9. Liver Biology/Pathobiology
    10. Special Article
    11. Reviews
    12. Hepatology Elsewhere
    13. Correspondence
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      Increased hepatotoxicity of tumor necrosis factor–related apoptosis-inducing ligand in diseased human liver (pages 1498–1508)

      Xandra Volkmann, Ute Fischer, Matthias J. Bahr, Michael Ott, Frank Lehner, Marion MacFarlane, Gerald M. Cohen, Michael P. Manns, Klaus Schulze-Osthoff and Heike Bantel

      Version of Record online: 17 AUG 2007 | DOI: 10.1002/hep.21846

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      Apoptotic hepatocyte DNA inhibits hepatic stellate cell chemotaxis via toll-like receptor 9 (pages 1509–1518)

      Azuma Watanabe, Ardeshir Hashmi, Dawidson Assis Gomes, Terrence Town, Abdallah Badou, Richard Anthony Flavell and Wajahat Zafar Mehal

      Version of Record online: 17 AUG 2007 | DOI: 10.1002/hep.21867

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      A high-fat diet and regulatory T cells influence susceptibility to endotoxin-induced liver injury (pages 1519–1529)

      Xiong Ma, Jing Hua, Abdiaziz R. Mohamood, Abdel Rahmin A. Hamad, Rajani Ravi and Zhiping Li

      Version of Record online: 27 JUL 2007 | DOI: 10.1002/hep.21823

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      The role of serpinb9/serine protease inhibitor 6 in preventing granzyme B–dependent hepatotoxicity (pages 1530–1540)

      Heather W. Stout-Delgado, Yonas Getachew, Thomas E. Rogers, Bonnie C. Miller and Dwain L. Thiele

      Version of Record online: 8 AUG 2007 | DOI: 10.1002/hep.21820

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      The oncofetal gene glypican 3 is regulated in the postnatal liver by zinc fingers and homeoboxes 2 and in the regenerating liver by alpha-fetoprotein regulator 2 (pages 1541–1547)

      Lorri A. Morford, Christina Davis, Lin Jin, Aneta Dobierzewska, Martha L. Peterson and Brett T. Spear

      Version of Record online: 1 AUG 2007 | DOI: 10.1002/hep.21825

  8. Liver Biology/Pathobiology

    1. Top of page
    2. Editorials
    3. Viral Hepatitis
    4. Steatohepatitis/Metabolic Liver Disease
    5. Hepatobiliary Malignancies
    6. Autoimmune, Cholestatic and Biliary Disease
    7. Liver Failure/Cirrhosis/Portal Hypertension
    8. Liver Injury/Regeneration
    9. Liver Biology/Pathobiology
    10. Special Article
    11. Reviews
    12. Hepatology Elsewhere
    13. Correspondence
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      Hepatic gene expression during treatment with peginterferon and ribavirin: Identifying molecular pathways for treatment response (pages 1548–1563)

      Jordan J. Feld, Santosh Nanda, Ying Huang, Weiping Chen, Maggie Cam, Susan N. Pusek, Lisa M. Schweigler, Dickens Theodore, Steven L. Zacks, T. Jake Liang and Michael W. Fried

      Version of Record online: 10 OCT 2007 | DOI: 10.1002/hep.21853

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      Signal transducer and activator of transcription 3 signaling within hepatocytes attenuates systemic inflammatory response and lethality in septic mice (pages 1564–1573)

      Ryotaro Sakamori, Tetsuo Takehara, Chihiro Ohnishi, Tomohide Tatsumi, Kazuyoshi Ohkawa, Kiyoshi Takeda, Shizuo Akira and Norio Hayashi

      Version of Record online: 17 AUG 2007 | DOI: 10.1002/hep.21837

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      Human skin fibroblasts: From mesodermal to hepatocyte-like differentiation (pages 1574–1585)

      Philippe A. Lysy, Françoise Smets, Catherine Sibille, Mustapha Najimi and Etienne M. Sokal

      Version of Record online: 29 OCT 2007 | DOI: 10.1002/hep.21839

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      Oxidative and electrophilic stress induces multidrug resistance–associated protein transporters via the nuclear factor-E2–related factor-2 transcriptional pathway (pages 1597–1610)

      Jonathan M. Maher, Matthew Z. Dieter, Lauren M. Aleksunes, Angela L. Slitt, Grace Guo, Yuji Tanaka, George L. Scheffer, Jefferson Y. Chan, Jose E. Manautou, Ying Chen, Timothy P. Dalton, Masayuki Yamamoto and Curtis D. Klaassen

      Version of Record online: 1 AUG 2007 | DOI: 10.1002/hep.21831

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      ADAM metallopeptidase with thrombospondin type 1 motif 2 inactivation reduces the extent and stability of carbon tetrachloride–induced hepatic fibrosis in mice (pages 1620–1631)

      Frédéric Kesteloot, Alexis Desmoulière, Isabelle Leclercq, Marc Thiry, Jorge E. Arrese, Darwin J. Prockop, Charles M. Lapière, Betty V. Nusgens and Alain Colige

      Version of Record online: 10 OCT 2007 | DOI: 10.1002/hep.21868

  9. Special Article

    1. Top of page
    2. Editorials
    3. Viral Hepatitis
    4. Steatohepatitis/Metabolic Liver Disease
    5. Hepatobiliary Malignancies
    6. Autoimmune, Cholestatic and Biliary Disease
    7. Liver Failure/Cirrhosis/Portal Hypertension
    8. Liver Injury/Regeneration
    9. Liver Biology/Pathobiology
    10. Special Article
    11. Reviews
    12. Hepatology Elsewhere
    13. Correspondence
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      Growth failure and outcomes in infants with biliary atresia: A report from the Biliary Atresia Research Consortium (pages 1632–1638)

      Patricia A. DeRusso, Wen Ye, Ross Shepherd, Barbara A. Haber, Benjamin L. Shneider, Peter F. Whitington, Kathleen B. Schwarz, Jorge A. Bezerra, Philip Rosenthal, Saul Karpen, Robert H. Squires, John C. Magee, Patricia R. Robuck, Ronald J. Sokol and Biliary Atresia Research Consortium

      Version of Record online: 10 OCT 2007 | DOI: 10.1002/hep.21923

  10. Reviews

    1. Top of page
    2. Editorials
    3. Viral Hepatitis
    4. Steatohepatitis/Metabolic Liver Disease
    5. Hepatobiliary Malignancies
    6. Autoimmune, Cholestatic and Biliary Disease
    7. Liver Failure/Cirrhosis/Portal Hypertension
    8. Liver Injury/Regeneration
    9. Liver Biology/Pathobiology
    10. Special Article
    11. Reviews
    12. Hepatology Elsewhere
    13. Correspondence
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      Keratins let liver live: Mutations predispose to liver disease and crosslinking generates Mallory-Denk bodies (pages 1639–1649)

      Nam-On Ku, Pavel Strnad, Bi-Hui Zhong, Guo-Zhong Tao and M. Bishr Omary

      Version of Record online: 29 OCT 2007 | DOI: 10.1002/hep.21976

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      The liver in celiac disease (pages 1650–1658)

      Alberto Rubio-Tapia and Joseph A. Murray

      Version of Record online: 29 OCT 2007 | DOI: 10.1002/hep.21949

  11. Hepatology Elsewhere

    1. Top of page
    2. Editorials
    3. Viral Hepatitis
    4. Steatohepatitis/Metabolic Liver Disease
    5. Hepatobiliary Malignancies
    6. Autoimmune, Cholestatic and Biliary Disease
    7. Liver Failure/Cirrhosis/Portal Hypertension
    8. Liver Injury/Regeneration
    9. Liver Biology/Pathobiology
    10. Special Article
    11. Reviews
    12. Hepatology Elsewhere
    13. Correspondence
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  12. Correspondence

    1. Top of page
    2. Editorials
    3. Viral Hepatitis
    4. Steatohepatitis/Metabolic Liver Disease
    5. Hepatobiliary Malignancies
    6. Autoimmune, Cholestatic and Biliary Disease
    7. Liver Failure/Cirrhosis/Portal Hypertension
    8. Liver Injury/Regeneration
    9. Liver Biology/Pathobiology
    10. Special Article
    11. Reviews
    12. Hepatology Elsewhere
    13. Correspondence
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      Changes in bile acid synthesis in gallstone disease: Cause, consequence, or neither? (page 1664)

      Marco Bertolotti, Chiara Gabbi, Claudia Anzivino, Lucia Carulli and Nicola Carulli

      Version of Record online: 29 OCT 2007 | DOI: 10.1002/hep.21942

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      Reply: (pages 1664–1665)

      Silvana Zanlungo, Juan Francisco Miquel and Flavio Nervi

      Version of Record online: 29 OCT 2007 | DOI: 10.1002/hep.21961

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      Reply: (page 1666)

      Winnie Yeo and Frankie K. F. Mo

      Version of Record online: 29 OCT 2007 | DOI: 10.1002/hep.21969

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      Dipsticks for spontaneous bacterial peritonitis: Comments on a long-awaited study report (pages 1666–1667)

      Anastasios Koulaouzidis, Elmuhtady Said, Anthia Gatopoulou and John Moschos

      Version of Record online: 29 OCT 2007 | DOI: 10.1002/hep.21817

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      Lower cutoff values for dipsticks may improve their accuracy in rapid diagnosis of spontanous bacterial peritonitis (page 1668)

      Antonio de Barros Lopes, Alexandre Araujo and Mario Reis Alvares-da Silva

      Version of Record online: 29 OCT 2007 | DOI: 10.1002/hep.21842

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      Insufficient sensitivity of reagent strips for spontaneous bacterial peritonitis (page 1669)

      Veit Gülberg, Alexander L. Gerbes, Tilman Sauerbruch and Beate Appenrodt

      Version of Record online: 29 OCT 2007 | DOI: 10.1002/hep.21856

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      Reply: (pages 1669–1670)

      Jean-Baptiste Nousbaum, Jean-François Cadranel and Club Francophone pour l'Etude de l'Hypertension Portale and l'Association Nationale des Hépato-Gastroentérologues des Hôpitaux Généraux de France

      Version of Record online: 29 OCT 2007 | DOI: 10.1002/hep.21997

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