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Hepatology

Cover image for Hepatology

January 2008

Volume 47, Issue 1

Pages 1–363

  1. Comment from the Editor

    1. Top of page
    2. Comment from the Editor
    3. Editorials
    4. Viral Hepatitis
    5. Steatohepatitis and Metabolic Liver Disease
    6. Hepatobiliary Malignancies
    7. Autoimmune, Cholestatic and Biliary Disease
    8. Liver Failure/Cirrhosis/Portal Hypertension
    9. Liver Injury/Regeneration
    10. Liver Biology/Pathobiology
    11. Special Article
    12. Reviews
    13. Hepatology Elsewhere
    14. Correspondence
    15. Correction
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      Conflict of interest policy (page 1)

      Keith Lindor, Jorge Rakela and John Fung

      Article first published online: 27 DEC 2007 | DOI: 10.1002/hep.22098

  2. Editorials

    1. Top of page
    2. Comment from the Editor
    3. Editorials
    4. Viral Hepatitis
    5. Steatohepatitis and Metabolic Liver Disease
    6. Hepatobiliary Malignancies
    7. Autoimmune, Cholestatic and Biliary Disease
    8. Liver Failure/Cirrhosis/Portal Hypertension
    9. Liver Injury/Regeneration
    10. Liver Biology/Pathobiology
    11. Special Article
    12. Reviews
    13. Hepatology Elsewhere
    14. Correspondence
    15. Correction
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  3. Viral Hepatitis

    1. Top of page
    2. Comment from the Editor
    3. Editorials
    4. Viral Hepatitis
    5. Steatohepatitis and Metabolic Liver Disease
    6. Hepatobiliary Malignancies
    7. Autoimmune, Cholestatic and Biliary Disease
    8. Liver Failure/Cirrhosis/Portal Hypertension
    9. Liver Injury/Regeneration
    10. Liver Biology/Pathobiology
    11. Special Article
    12. Reviews
    13. Hepatology Elsewhere
    14. Correspondence
    15. Correction
    1. You have free access to this content
      Hepatitis C virus cell-cell transmission in hepatoma cells in the presence of neutralizing antibodies (pages 17–24)

      Jennifer M. Timpe, Zania Stamataki, Adam Jennings, Ke Hu, Michelle J. Farquhar, Helen J. Harris, Anne Schwarz, Isabelle Desombere, Geert Leroux Roels, Peter Balfe and Jane A. McKeating

      Article first published online: 16 OCT 2007 | DOI: 10.1002/hep.21959

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      Hepatitis B virus precore protein augments genetic immunizations of the truncated hepatitis C virus core in BALB/c mice (pages 25–34)

      Guoyang Liao, Yue Wang, Jinhai Chang, Tao Bian, Wenjie Tan, Mingbo Sun, Weidong Li, Huijuan Yang, Junying Chen, Xinwen Zhang, Shengli Bi, Masao Omata and Shude Jiang

      Article first published online: 11 DEC 2007 | DOI: 10.1002/hep.21992

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      Pegylated interferon alfa and ribavirin for 14 versus 24 weeks in patients with hepatitis C virus genotype 2 or 3 and rapid virological response (pages 35–42)

      Olav Dalgard, Kristian Bjøro, Helmer Ring-Larsen, Einar Bjornsson, Mona Holberg-Petersen, Eva Skovlund, Olle Reichard, Bjørn Myrvang, Bo Sundelöf, Ståle Ritland, Kjell Hellum, Aril Frydén, Jon Florholmen and Hans Verbaan

      Article first published online: 1 NOV 2007 | DOI: 10.1002/hep.21975

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      Individualized treatment duration for hepatitis C genotype 1 patients: A randomized controlled trial (pages 43–50)

      Alessandra Mangia, Nicola Minerva, Donato Bacca, Raffaele Cozzolongo, Giovanni L. Ricci, Vito Carretta, Francesco Vinelli, Gaetano Scotto, Giuseppe Montalto, Mario Romano, Giuseppe Cristofaro, Leonardo Mottola, Fulvio Spirito and Angelo Andriulli

      Article first published online: 10 DEC 2007 | DOI: 10.1002/hep.22061

  4. Steatohepatitis and Metabolic Liver Disease

    1. Top of page
    2. Comment from the Editor
    3. Editorials
    4. Viral Hepatitis
    5. Steatohepatitis and Metabolic Liver Disease
    6. Hepatobiliary Malignancies
    7. Autoimmune, Cholestatic and Biliary Disease
    8. Liver Failure/Cirrhosis/Portal Hypertension
    9. Liver Injury/Regeneration
    10. Liver Biology/Pathobiology
    11. Special Article
    12. Reviews
    13. Hepatology Elsewhere
    14. Correspondence
    15. Correction
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      Increased mediastinal fat and impaired left ventricular energy metabolism in young men with newly found fatty liver (pages 51–58)

      Gianluca Perseghin, Guido Lattuada, Francesco De Cobelli, Antonio Esposito, Elena Belloni, Georgia Ntali, Francesca Ragogna, Tamara Canu, Paola Scifo, Alessandro Del Maschio and Livio Luzi

      Article first published online: 22 OCT 2007 | DOI: 10.1002/hep.21983

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      Ethanol induces oxidative stress in primary rat hepatocytes through the early involvement of lipid raft clustering (pages 59–70)

      Philippe Nourissat, Marion Travert, Martine Chevanne, Xavier Tekpli, Amélie Rebillard, Gwenaelle Le Moigne-Müller, Mary Rissel, Josiane Cillard, Marie-Thérèse Dimanche-Boitrel, Dominique Lagadic-Gossmann and Odile Sergent

      Article first published online: 25 NOV 2007 | DOI: 10.1002/hep.21958

  5. Hepatobiliary Malignancies

    1. Top of page
    2. Comment from the Editor
    3. Editorials
    4. Viral Hepatitis
    5. Steatohepatitis and Metabolic Liver Disease
    6. Hepatobiliary Malignancies
    7. Autoimmune, Cholestatic and Biliary Disease
    8. Liver Failure/Cirrhosis/Portal Hypertension
    9. Liver Injury/Regeneration
    10. Liver Biology/Pathobiology
    11. Special Article
    12. Reviews
    13. Hepatology Elsewhere
    14. Correspondence
    15. Correction
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      Safety and efficacy of 90Y radiotherapy for hepatocellular carcinoma with and without portal vein thrombosis (pages 71–81)

      Laura M. Kulik, Brian I. Carr, Mary F. Mulcahy, Robert J. Lewandowski, Bassel Atassi, Robert K. Ryu, Kent T. Sato, Al Benson III, Albert A. Nemcek Jr., Vanessa L. Gates, Michael Abecassis, Reed A. Omary and Riad Salem

      Article first published online: 20 NOV 2007 | DOI: 10.1002/hep.21980

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      Cholangiocarcinoma in primary sclerosing cholangitis is associated with NKG2D polymorphisms (pages 90–96)

      Espen Melum, Tom H. Karlsen, Erik Schrumpf, Annika Bergquist, Erik Thorsby, Kirsten M. Boberg and Benedicte A. Lie

      Article first published online: 19 NOV 2007 | DOI: 10.1002/hep.21964

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      Diagnosis of hepatic nodules 20 mm or smaller in cirrhosis: Prospective validation of the noninvasive diagnostic criteria for hepatocellular carcinoma (pages 97–104)

      Alejandro Forner, Ramón Vilana, Carmen Ayuso, Lluís Bianchi, Manel Solé, Juan Ramón Ayuso, Loreto Boix, Margarita Sala, María Varela, Josep M Llovet, Concepció Brú and Jordi Bruix

      Article first published online: 10 DEC 2007 | DOI: 10.1002/hep.21966

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      Transfer of suppressor of cytokine signaling 3 by an oncolytic adenovirus induces potential antitumor activities in hepatocellular carcinoma (pages 105–112)

      Qiang Cui, Wei Jiang, Yingxin Wang, Chen Lv, Jingjing Luo, Wei Zhang, Fang Lin, Yuexiang Yin, Rong Cai, Ping Wei and Cheng Qian

      Article first published online: 12 OCT 2007 | DOI: 10.1002/hep.21951

  6. Autoimmune, Cholestatic and Biliary Disease

    1. Top of page
    2. Comment from the Editor
    3. Editorials
    4. Viral Hepatitis
    5. Steatohepatitis and Metabolic Liver Disease
    6. Hepatobiliary Malignancies
    7. Autoimmune, Cholestatic and Biliary Disease
    8. Liver Failure/Cirrhosis/Portal Hypertension
    9. Liver Injury/Regeneration
    10. Liver Biology/Pathobiology
    11. Special Article
    12. Reviews
    13. Hepatology Elsewhere
    14. Correspondence
    15. Correction
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      Pivotal role of Smad3 in a mouse model of T cell–mediated hepatitis (pages 113–126)

      Michael Kremer, Ashley W. Perry, Richard J. Milton, Richard A. Rippe, Michael D. Wheeler and Ian N. Hines

      Article first published online: 19 NOV 2007 | DOI: 10.1002/hep.21956

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      A polymorphism of the alpha1-antitrypsin gene represents a risk factor for liver disease (pages 127–132)

      Sally Chappell, Nedim Hadzic, Robert Stockley, Tamar Guetta-Baranes, Kevin Morgan and Noor Kalsheker

      Article first published online: 30 OCT 2007 | DOI: 10.1002/hep.21979

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      Impact of inflammatory bowel disease and ursodeoxycholic acid therapy on small-duct primary sclerosing cholangitis (pages 133–142)

      Phunchai Charatcharoenwitthaya, Paul Angulo, Felicity B. Enders and Keith D. Lindor

      Article first published online: 8 NOV 2007 | DOI: 10.1002/hep.21960

  7. Liver Failure/Cirrhosis/Portal Hypertension

    1. Top of page
    2. Comment from the Editor
    3. Editorials
    4. Viral Hepatitis
    5. Steatohepatitis and Metabolic Liver Disease
    6. Hepatobiliary Malignancies
    7. Autoimmune, Cholestatic and Biliary Disease
    8. Liver Failure/Cirrhosis/Portal Hypertension
    9. Liver Injury/Regeneration
    10. Liver Biology/Pathobiology
    11. Special Article
    12. Reviews
    13. Hepatology Elsewhere
    14. Correspondence
    15. Correction
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      Present status of ABO-incompatible living donor liver transplantation in Japan (pages 143–152)

      Hiroto Egawa, Satoshi Teramukai, Hironori Haga, Minoru Tanabe, Masanori Fukushima and Motohide Shimazu

      Article first published online: 10 OCT 2007 | DOI: 10.1002/hep.21928

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      Platelet count is not a predictor of the presence or development of gastroesophageal varices in cirrhosis (pages 153–159)

      Amir A. Qamar, Norman D. Grace, Roberto J. Groszmann, Guadalupe Garcia-Tsao, Jaime Bosch, Andrew K. Burroughs, Rie Maurer, Ramon Planas, Angels Escorsell, Juan Carlos Garcia-Pagan, David Patch, Daniel S. Matloff and Robert Makuch

      Article first published online: 27 DEC 2007 | DOI: 10.1002/hep.21941

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  8. Liver Injury/Regeneration

    1. Top of page
    2. Comment from the Editor
    3. Editorials
    4. Viral Hepatitis
    5. Steatohepatitis and Metabolic Liver Disease
    6. Hepatobiliary Malignancies
    7. Autoimmune, Cholestatic and Biliary Disease
    8. Liver Failure/Cirrhosis/Portal Hypertension
    9. Liver Injury/Regeneration
    10. Liver Biology/Pathobiology
    11. Special Article
    12. Reviews
    13. Hepatology Elsewhere
    14. Correspondence
    15. Correction
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      Matrix metalloproteinase inhibition protects rat livers from prolonged cold ischemia–warm reperfusion injury (pages 177–185)

      Virginie Defamie, Marina Laurens, Damiano Patrono, Laurent Devel, Antoine Brault, Marie-Christine Saint-Paul, Athanasios Yiotakis, Pascal Barbry, Jean Gugenheim, Dominique Crenesse, Vincent Dive, Pierre-Michel Huet and Bernard Mari

      Article first published online: 15 NOV 2007 | DOI: 10.1002/hep.21929

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      Metalloproteinase-9 deficiency protects against hepatic ischemia/reperfusion injury (pages 186–198)

      Takashi Hamada, Constantino Fondevila, Ronald W. Busuttil and Ana J. Coito

      Article first published online: 19 SEP 2007 | DOI: 10.1002/hep.21922

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      Type I, but not type II, interferon is critical in liver injury induced after ischemia and reperfusion (pages 199–206)

      Yuan Zhai, Bo Qiao, Feng Gao, Xiuda Shen, Andrew Vardanian, Ronald W. Busuttil and Jerzy W. Kupiec-Weglinski

      Article first published online: 12 OCT 2007 | DOI: 10.1002/hep.21970

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      CXCL10 regulates liver innate immune response against ischemia and reperfusion injury (pages 207–214)

      Yuan Zhai, Xiu-Da Shen, Feng Gao, Alice Zhao, Maria Cecilia Freitas, Charles Lassman, Andrew D. Luster, Ronald W. Busuttil and Jerzy W. Kupiec-Weglinski

      Article first published online: 27 NOV 2007 | DOI: 10.1002/hep.21986

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      Peroxisome proliferator-activated receptor-γ protects against hepatic ischemia/reperfusion injury in mice (pages 215–224)

      Satoshi Kuboki, Thomas Shin, Nadine Huber, Thorsten Eismann, Elizabeth Galloway, Rebecca Schuster, John Blanchard, Basilia Zingarelli and Alex B. Lentsch

      Article first published online: 12 DEC 2007 | DOI: 10.1002/hep.21963

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      Peroxisome proliferator-activated receptor-β/δ protects against chemically induced liver toxicity in mice (pages 225–235)

      Weiwei Shan, Christopher J. Nicol, Shinji Ito, Moses T. Bility, Mary J. Kennett, Jerrold M. Ward, Frank J. Gonzalez and Jeffrey M. Peters

      Article first published online: 25 NOV 2007 | DOI: 10.1002/hep.21925

  9. Liver Biology/Pathobiology

    1. Top of page
    2. Comment from the Editor
    3. Editorials
    4. Viral Hepatitis
    5. Steatohepatitis and Metabolic Liver Disease
    6. Hepatobiliary Malignancies
    7. Autoimmune, Cholestatic and Biliary Disease
    8. Liver Failure/Cirrhosis/Portal Hypertension
    9. Liver Injury/Regeneration
    10. Liver Biology/Pathobiology
    11. Special Article
    12. Reviews
    13. Hepatology Elsewhere
    14. Correspondence
    15. Correction
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      Minocycline and N-methyl-4-isoleucine cyclosporin (NIM811) mitigate storage/reperfusion injury after rat liver transplantation through suppression of the mitochondrial permeability transition (pages 236–246)

      Tom P. Theruvath, Zhi Zhong, Peter Pediaditakis, Venkat K. Ramshesh, Robert T. Currin, Andrey Tikunov, Ekhson Holmuhamedov and John J. Lemasters

      Article first published online: 19 NOV 2007 | DOI: 10.1002/hep.21912

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      Stabilization of β-catenin affects mouse embryonic liver growth and hepatoblast fate (pages 247–258)

      Thomas Decaens, Cécile Godard, Aurélien de Reyniès, David S. Rickman, François Tronche, Jean-Pierre Couty, Christine Perret and Sabine Colnot

      Article first published online: 25 NOV 2007 | DOI: 10.1002/hep.21952

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      Increased osteoclast formation and activity by peripheral blood mononuclear cells in chronic liver disease patients with osteopenia (pages 259–267)

      Brenda J. Olivier, Ton Schoenmaker, Reina E. Mebius, Vincent Everts, Chris J. Mulder, Karin M. J. van Nieuwkerk, Teun J. de Vries and Schalk W. van der Merwe

      Article first published online: 16 NOV 2007 | DOI: 10.1002/hep.21971

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      ATP8B1 requires an accessory protein for endoplasmic reticulum exit and plasma membrane lipid flippase activity (pages 268–278)

      Coen C. Paulusma, Dineke E. Folmer, Kam S. Ho-Mok, D. Rudi de Waart, Petra M. Hilarius, Arthur J. Verhoeven and Ronald P. J. Oude Elferink

      Article first published online: 19 OCT 2007 | DOI: 10.1002/hep.21950

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      Hepatocyte transplantation and drug-induced perturbations in liver cell compartments (pages 279–287)

      Yao-Ming Wu, Brigid Joseph, Ekaterine Berishvili, Vinay Kumaran and Sanjeev Gupta

      Article first published online: 12 OCT 2007 | DOI: 10.1002/hep.21937

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      Wnt/β-catenin signaling mediates oval cell response in rodents (pages 288–295)

      Udayan Apte, Michael D. Thompson, Shanshan Cui, Bowen Liu, Benjamin Cieply and Satdarshan P. S. Monga

      Article first published online: 10 OCT 2007 | DOI: 10.1002/hep.21973

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      Tolerogenic maturation of liver sinusoidal endothelial cells promotes B7-homolog 1-dependent CD8+ T cell tolerance (pages 296–305)

      Linda Diehl, Anna Schurich, Regina Grochtmann, Silke Hegenbarth, Lieping Chen and Percy A. Knolle

      Article first published online: 1 NOV 2007 | DOI: 10.1002/hep.21965

  10. Special Article

    1. Top of page
    2. Comment from the Editor
    3. Editorials
    4. Viral Hepatitis
    5. Steatohepatitis and Metabolic Liver Disease
    6. Hepatobiliary Malignancies
    7. Autoimmune, Cholestatic and Biliary Disease
    8. Liver Failure/Cirrhosis/Portal Hypertension
    9. Liver Injury/Regeneration
    10. Liver Biology/Pathobiology
    11. Special Article
    12. Reviews
    13. Hepatology Elsewhere
    14. Correspondence
    15. Correction
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      Mechanisms of action of interferon and ribavirin in chronic hepatitis C: Summary of a workshop (pages 306–320)

      Raymond T. Chung, Michael Gale Jr, Stephen J. Polyak, Stanley M. Lemon, T. Jake Liang and Jay H. Hoofnagle

      Article first published online: 27 DEC 2007 | DOI: 10.1002/hep.22070

  11. Reviews

    1. Top of page
    2. Comment from the Editor
    3. Editorials
    4. Viral Hepatitis
    5. Steatohepatitis and Metabolic Liver Disease
    6. Hepatobiliary Malignancies
    7. Autoimmune, Cholestatic and Biliary Disease
    8. Liver Failure/Cirrhosis/Portal Hypertension
    9. Liver Injury/Regeneration
    10. Liver Biology/Pathobiology
    11. Special Article
    12. Reviews
    13. Hepatology Elsewhere
    14. Correspondence
    15. Correction
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      Acute hepatitis C virus infection: A chronic problem (pages 321–331)

      Jason T. Blackard, M. Tarek Shata, Norah J. Shire and Kenneth E. Sherman

      Article first published online: 27 DEC 2007 | DOI: 10.1002/hep.21902

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      Magnetic resonance imaging of hepatic fibrosis: Emerging clinical applications (pages 332–342)

      Jayant A. Talwalkar, Meng Yin, Jeff L. Fidler, Schuyler O. Sanderson, Patrick S. Kamath and Richard L. Ehman

      Article first published online: 27 DEC 2007 | DOI: 10.1002/hep.21972

  12. Hepatology Elsewhere

    1. Top of page
    2. Comment from the Editor
    3. Editorials
    4. Viral Hepatitis
    5. Steatohepatitis and Metabolic Liver Disease
    6. Hepatobiliary Malignancies
    7. Autoimmune, Cholestatic and Biliary Disease
    8. Liver Failure/Cirrhosis/Portal Hypertension
    9. Liver Injury/Regeneration
    10. Liver Biology/Pathobiology
    11. Special Article
    12. Reviews
    13. Hepatology Elsewhere
    14. Correspondence
    15. Correction
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  13. Correspondence

    1. Top of page
    2. Comment from the Editor
    3. Editorials
    4. Viral Hepatitis
    5. Steatohepatitis and Metabolic Liver Disease
    6. Hepatobiliary Malignancies
    7. Autoimmune, Cholestatic and Biliary Disease
    8. Liver Failure/Cirrhosis/Portal Hypertension
    9. Liver Injury/Regeneration
    10. Liver Biology/Pathobiology
    11. Special Article
    12. Reviews
    13. Hepatology Elsewhere
    14. Correspondence
    15. Correction
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      Reply: (pages 352–353)

      Richard K. Sterling

      Article first published online: 27 DEC 2007 | DOI: 10.1002/hep.22067

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      FibroTest has better diagnostic and prognostic values than the aspartate aminotransferase-to-platelet ratio index in patients with chronic hepatitis C (pages 353–354)

      Rachel Morra, Pascal Lebray, Patrick Ingiliz, Yen Ngo, Mona Munteanu, Vlad Ratziu and Thierry Poynard

      Article first published online: 27 DEC 2007 | DOI: 10.1002/hep.22046

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      Reply: (pages 354–356)

      Robert P. Myers and Abdel Aziz M. Shaheen

      Article first published online: 27 DEC 2007 | DOI: 10.1002/hep.22069

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      Reply: (pages 356–357)

      Lisa I. Backus, Derek B. Boothroyd, Barbara R. Phillips and Larry A. Mole

      Article first published online: 27 DEC 2007 | DOI: 10.1002/hep.22095

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      Reply: (pages 357–358)

      Savino Bruno, Patrick Maisonneuve and Mario U. Mondelli

      Article first published online: 27 DEC 2007 | DOI: 10.1002/hep.22096

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      Reply: (page 360)

      Geoffrey Nguyen and Paul J. Thuluvath

      Article first published online: 27 DEC 2007 | DOI: 10.1002/hep.22147

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      Sepsis-induced cholestasis (page 361)

      Ivo Giovannini, Carlo Chiarla, Felice Giuliante, Maria Vellone, Francesco Ardito and Gennaro Nuzzo

      Article first published online: 27 DEC 2007 | DOI: 10.1002/hep.21857

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      The neck-liver axis. Madelung disease as further evidence for an impact of body fat distribution on hepatic histology (pages 361–362)

      Stefano Ballestri, Amedeo Lonardo, Lucia Carulli, Matteo Ricchi, Lorena Bertozzi, Giorgio De Santis, Mario Bondi and Paola Loria

      Article first published online: 27 DEC 2007 | DOI: 10.1002/hep.21977

  14. Correction

    1. Top of page
    2. Comment from the Editor
    3. Editorials
    4. Viral Hepatitis
    5. Steatohepatitis and Metabolic Liver Disease
    6. Hepatobiliary Malignancies
    7. Autoimmune, Cholestatic and Biliary Disease
    8. Liver Failure/Cirrhosis/Portal Hypertension
    9. Liver Injury/Regeneration
    10. Liver Biology/Pathobiology
    11. Special Article
    12. Reviews
    13. Hepatology Elsewhere
    14. Correspondence
    15. Correction
    1. You have free access to this content
      Correction (page 363)

      Article first published online: 27 DEC 2007 | DOI: 10.1002/hep.22188

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