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Hepatology

Cover image for Vol. 47 Issue 5

May 2008

Volume 47, Issue 5

Pages 1431–1798

  1. Comments from the Editors

    1. Top of page
    2. Comments from the Editors
    3. Editorial
    4. Viral Hepatitis
    5. Steatohepatitis/Metabolic Liver Disease
    6. Hepatobiliary Malignancies
    7. Autoimmune, Cholestatic and Biliary Disease
    8. Liver Failure/Cirrhosis/Portal Hypertension
    9. Liver Injury/Regeneration
    10. Liver Biology/Pathobiology
    11. Meeting Report
    12. Review
    13. Hepatology Elsewhere
    14. Correspondence
    1. You have full text access to this OnlineOpen article
  2. Editorial

    1. Top of page
    2. Comments from the Editors
    3. Editorial
    4. Viral Hepatitis
    5. Steatohepatitis/Metabolic Liver Disease
    6. Hepatobiliary Malignancies
    7. Autoimmune, Cholestatic and Biliary Disease
    8. Liver Failure/Cirrhosis/Portal Hypertension
    9. Liver Injury/Regeneration
    10. Liver Biology/Pathobiology
    11. Meeting Report
    12. Review
    13. Hepatology Elsewhere
    14. Correspondence
    1. You have full text access to this OnlineOpen article
  3. Viral Hepatitis

    1. Top of page
    2. Comments from the Editors
    3. Editorial
    4. Viral Hepatitis
    5. Steatohepatitis/Metabolic Liver Disease
    6. Hepatobiliary Malignancies
    7. Autoimmune, Cholestatic and Biliary Disease
    8. Liver Failure/Cirrhosis/Portal Hypertension
    9. Liver Injury/Regeneration
    10. Liver Biology/Pathobiology
    11. Meeting Report
    12. Review
    13. Hepatology Elsewhere
    14. Correspondence
    1. You have full text access to this OnlineOpen article
      Apolipoprotein B–dependent hepatitis C virus secretion is inhibited by the grapefruit flavonoid naringenin (pages 1437–1445)

      Yaakov Nahmias, Jonathan Goldwasser, Monica Casali, Daan van Poll, Takaji Wakita, Raymond T. Chung and Martin L. Yarmush

      Article first published online: 7 JAN 2008 | DOI: 10.1002/hep.22197

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      Ribavirin exposure after the first dose is predictive of sustained virological response in chronic hepatitis C (pages 1453–1461)

      Véronique Loustaud-Ratti, Sophie Alain, Annick Rousseau, Isabelle Fouchard Hubert, François Ludovic Sauvage, Pierre Marquet, François Denis, Françoise Lunel, Paul Calès, Annie Lefebvre, Anne-Laure Fauchais, Eric Liozon and Elisabeth Vidal

      Article first published online: 14 JAN 2008 | DOI: 10.1002/hep.22217

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      Acetylsalicylic acid inhibits hepatitis C virus RNA and protein expression through cyclooxygenase 2 signaling pathways (pages 1462–1472)

      Karina Trujillo-Murillo, Ana Rosa Rincón-Sánchez, Herminia Martínez-Rodríguez, Francisco Bosques-Padilla, Javier Ramos-Jiménez, Hugo A. Barrera-Saldaña, Marcos Rojkind and Ana María Rivas-Estilla

      Article first published online: 14 JAN 2008 | DOI: 10.1002/hep.22215

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      Comprehensive evaluation of hepatitis B virus reverse transcriptase substitutions associated with entecavir resistance (pages 1473–1482)

      Carl J. Baldick, Daniel J. Tenney, Charles E. Mazzucco, Betsy J. Eggers, Ronald E. Rose, Kevin A. Pokornowski, Cheng F. Yu and Richard J. Colonno

      Article first published online: 14 JAN 2008 | DOI: 10.1002/hep.22211

  4. Steatohepatitis/Metabolic Liver Disease

    1. Top of page
    2. Comments from the Editors
    3. Editorial
    4. Viral Hepatitis
    5. Steatohepatitis/Metabolic Liver Disease
    6. Hepatobiliary Malignancies
    7. Autoimmune, Cholestatic and Biliary Disease
    8. Liver Failure/Cirrhosis/Portal Hypertension
    9. Liver Injury/Regeneration
    10. Liver Biology/Pathobiology
    11. Meeting Report
    12. Review
    13. Hepatology Elsewhere
    14. Correspondence
    1. You have full text access to this OnlineOpen article
      Cytochrome P450 2E1 contributes to ethanol-induced fatty liver in mice (pages 1483–1494)

      Yongke Lu, Jian Zhuge, Xiaodong Wang, Jingxiang Bai and Arthur I. Cederbaum

      Article first published online: 21 JAN 2008 | DOI: 10.1002/hep.22222

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      The lysosomal-mitochondrial axis in free fatty acid–induced hepatic lipotoxicity (pages 1495–1503)

      ZhengZheng Li, Michael Berk, Thomas M. McIntyre, Gregory J. Gores and Ariel E. Feldstein

      Article first published online: 20 DEC 2007 | DOI: 10.1002/hep.22183

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      Noninvasive assessment of hepatic lipid composition: Advancing understanding and management of fatty liver disorders (pages 1513–1523)

      Nathan A. Johnson, David W. Walton, Toos Sachinwalla, Campbell H. Thompson, Kate Smith, Patricia A. Ruell, Stephen R. Stannard and Jacob George

      Article first published online: 21 JAN 2008 | DOI: 10.1002/hep.22220

  5. Hepatobiliary Malignancies

    1. Top of page
    2. Comments from the Editors
    3. Editorial
    4. Viral Hepatitis
    5. Steatohepatitis/Metabolic Liver Disease
    6. Hepatobiliary Malignancies
    7. Autoimmune, Cholestatic and Biliary Disease
    8. Liver Failure/Cirrhosis/Portal Hypertension
    9. Liver Injury/Regeneration
    10. Liver Biology/Pathobiology
    11. Meeting Report
    12. Review
    13. Hepatology Elsewhere
    14. Correspondence
    1. You have full text access to this OnlineOpen article
      Granulin-epithelin precursor as a therapeutic target for hepatocellular carcinoma (pages 1524–1532)

      Jenny C. Ho, Ying Chi Ip, Siu Tim Cheung, Yuk Ting Lee, Kui Fat Chan, San Yu Wong and Sheung Tat Fan

      Article first published online: 7 JAN 2008 | DOI: 10.1002/hep.22191

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      TIS21 negatively regulates hepatocarcinogenesis by disruption of cyclin B1–Forkhead box M1 regulation loop (pages 1533–1543)

      Tae Jun Park, Ji Yeon Kim, S. Paul Oh, So Young Kang, Bong Wan Kim, Hee Jung Wang, Kye Yong Song, Hyoung Chin Kim and In Kyoung Lim

      Article first published online: 14 JAN 2008 | DOI: 10.1002/hep.22212

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      Clinicopathological study on cholangiolocellular carcinoma suggesting hepatic progenitor cell origin (pages 1544–1556)

      Mina Komuta, Bart Spee, Sara Vander Borght, Rita De Vos, Chris Verslype, Raymond Aerts, Hirohisa Yano, Tetsuya Suzuki, Masanori Matsuda, Hideki Fujii, Valeer J. Desmet, Masamichi Kojiro and Tania Roskams

      Article first published online: 29 JAN 2008 | DOI: 10.1002/hep.22238

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  6. Autoimmune, Cholestatic and Biliary Disease

    1. Top of page
    2. Comments from the Editors
    3. Editorial
    4. Viral Hepatitis
    5. Steatohepatitis/Metabolic Liver Disease
    6. Hepatobiliary Malignancies
    7. Autoimmune, Cholestatic and Biliary Disease
    8. Liver Failure/Cirrhosis/Portal Hypertension
    9. Liver Injury/Regeneration
    10. Liver Biology/Pathobiology
    11. Meeting Report
    12. Review
    13. Hepatology Elsewhere
    14. Correspondence
    1. You have full text access to this OnlineOpen article
      Temporal-spatial activation of apoptosis and epithelial injury in murine experimental biliary atresia (pages 1567–1577)

      Nissa Erickson, Sujit Kumar Mohanty, Pranavkumar Shivakumar, Gregg Sabla, Ranajit Chakraborty and Jorge A. Bezerra

      Article first published online: 21 JAN 2008 | DOI: 10.1002/hep.22229

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      Loss of orphan receptor small heterodimer partner sensitizes mice to liver injury from obstructive cholestasis (pages 1578–1586)

      Young Joo Park, Mohammed Qatanani, Steven S. Chua, Jennifer L. LaRey, Stacy A. Johnson, Mitsuhiro Watanabe, David D. Moore and Yoon Kwang Lee

      Article first published online: 7 JAN 2008 | DOI: 10.1002/hep.22196

  7. Liver Failure/Cirrhosis/Portal Hypertension

    1. Top of page
    2. Comments from the Editors
    3. Editorial
    4. Viral Hepatitis
    5. Steatohepatitis/Metabolic Liver Disease
    6. Hepatobiliary Malignancies
    7. Autoimmune, Cholestatic and Biliary Disease
    8. Liver Failure/Cirrhosis/Portal Hypertension
    9. Liver Injury/Regeneration
    10. Liver Biology/Pathobiology
    11. Meeting Report
    12. Review
    13. Hepatology Elsewhere
    14. Correspondence
    1. You have full text access to this OnlineOpen article
      A prospective evaluation of computerized tomographic (CT) scanning as a screening modality for esophageal varices (pages 1587–1594)

      Roman E. Perri, Michael V. Chiorean, Jeff L. Fidler, Joel G. Fletcher, Jayant A. Talwalkar, Linda Stadheim, Nilay D. Shah and Patrick S. Kamath

      Article first published online: 21 JAN 2008 | DOI: 10.1002/hep.22219

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      Esophageal capsule endoscopy for screening and surveillance of esophageal varices in patients with portal hypertension (pages 1595–1603)

      Roberto de Franchis, Glenn M. Eisen, Loren Laine, Inaki Fernandez-Urien, Juan Manuel Herrerias, Russell D. Brown, Laurel Fisher, Hugo E. Vargas, John Vargo, Julie Thompson and Rami Eliakim

      Article first published online: 21 JAN 2008 | DOI: 10.1002/hep.22227

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      Recombinant factor VIIa for variceal bleeding in patients with advanced cirrhosis: A randomized, controlled trial (pages 1604–1614)

      Jaime Bosch, Dominique Thabut, Agustín Albillos, Nicolas Carbonell, Julius Spicak, Julien Massard, Gennaro D'Amico, Didier Lebrec, Roberto de Franchis, Søren Fabricius, Yan Cai and Flemming Bendtsen

      Article first published online: 14 JAN 2008 | DOI: 10.1002/hep.22216

  8. Liver Injury/Regeneration

    1. Top of page
    2. Comments from the Editors
    3. Editorial
    4. Viral Hepatitis
    5. Steatohepatitis/Metabolic Liver Disease
    6. Hepatobiliary Malignancies
    7. Autoimmune, Cholestatic and Biliary Disease
    8. Liver Failure/Cirrhosis/Portal Hypertension
    9. Liver Injury/Regeneration
    10. Liver Biology/Pathobiology
    11. Meeting Report
    12. Review
    13. Hepatology Elsewhere
    14. Correspondence
    1. You have full text access to this OnlineOpen article
      Selective portal vein embolization and ligation trigger different regenerative responses in the rat liver (pages 1615–1623)

      Katarzyna Furrer, Yinghua Tian, Thomas Pfammatter, Wolfram Jochum, Ashraf Mohammad El-Badry, Rolf Graf and Pierre-Alain Clavien

      Article first published online: 19 DEC 2007 | DOI: 10.1002/hep.22164

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      Caspase activation is associated with spontaneous recovery from acute liver failure (pages 1624–1633)

      Xandra Volkmann, Matthias Anstaett, Johannes Hadem, Penelope Stiefel, Matthias J. Bahr, Frank Lehner, Michael P. Manns, Klaus Schulze-Osthoff and Heike Bantel

      Article first published online: 24 JAN 2008 | DOI: 10.1002/hep.22237

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      Mesenchymal stem cell–derived molecules directly modulate hepatocellular death and regeneration in vitro and in vivo (pages 1634–1643)

      Daan van Poll, Biju Parekkadan, Cheul H. Cho, François Berthiaume, Yaakov Nahmias, Arno W. Tilles and Martin L. Yarmush

      Article first published online: 24 JAN 2008 | DOI: 10.1002/hep.22236

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      Suppressor of cytokine signaling 1 protects mice against concanavalin A–induced hepatitis by inhibiting apoptosis (pages 1644–1654)

      Takehiro Torisu, Mako Nakaya, Satoko Watanabe, Masayuki Hashimoto, Hideyuki Yoshida, Takatoshi Chinen, Ryoko Yoshida, Fuyuki Okamoto, Toshikatsu Hanada, Kumiko Torisu, Giichi Takaesu, Takashi Kobayashi, Hideo Yasukawa and Akihiko Yoshimura

      Article first published online: 14 JAN 2008 | DOI: 10.1002/hep.22214

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  9. Liver Biology/Pathobiology

    1. Top of page
    2. Comments from the Editors
    3. Editorial
    4. Viral Hepatitis
    5. Steatohepatitis/Metabolic Liver Disease
    6. Hepatobiliary Malignancies
    7. Autoimmune, Cholestatic and Biliary Disease
    8. Liver Failure/Cirrhosis/Portal Hypertension
    9. Liver Injury/Regeneration
    10. Liver Biology/Pathobiology
    11. Meeting Report
    12. Review
    13. Hepatology Elsewhere
    14. Correspondence
    1. You have full text access to this OnlineOpen article
      β-Catenin deletion in hepatoblasts disrupts hepatic morphogenesis and survival during mouse development (pages 1667–1679)

      Xinping Tan, Youzhong Yuan, Gang Zeng, Udayan Apte, Michael D. Thompson, Benjamin Cieply, Donna B. Stolz, George K. Michalopoulos, Klaus H. Kaestner and Satdarshan P.S. Monga

      Article first published online: 21 JAN 2008 | DOI: 10.1002/hep.22225

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      Lymphoid neogenesis and immune infiltration in aged liver (pages 1680–1690)

      Pallavi Singh, Zeynep Z. Coskun, Catriona Goode, Adam Dean, LuAnn Thompson-Snipes and Gretchen Darlington

      Article first published online: 21 JAN 2008 | DOI: 10.1002/hep.22224

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      Hepatocytes can induce death of contacted cells via perforin-dependent mechanism (pages 1691–1701)

      Clifford S. Guy, Sherri L. Rankin, Jinguo Wang and Tomasz I. Michalak

      Article first published online: 21 JAN 2008 | DOI: 10.1002/hep.22228

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      A facile method for somatic, lifelong manipulation of multiple genes in the mouse liver (pages 1714–1724)

      Kirk J. Wangensteen, Andrew Wilber, Vincent W. Keng, Zhiying He, Ilze Matise, Laura Wangensteen, Corey M. Carson, Yixin Chen, Clifford J. Steer, R. Scott McIvor, David A. Largaespada, Xin Wang and Stephen C. Ekker

      Article first published online: 7 JAN 2008 | DOI: 10.1002/hep.22195

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      Impaired autophagy: A mechanism of mitochondrial dysfunction in anoxic rat hepatocytes (pages 1725–1736)

      Jae-Sung Kim, Takashi Nitta, Dagmara Mohuczy, Kerri A. O'Malley, Lyle L. Moldawer, William A. Dunn Jr and Kevin E. Behrns

      Article first published online: 20 DEC 2007 | DOI: 10.1002/hep.22187

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      The role of Hfe in transferrin-bound iron uptake by hepatocytes (pages 1737–1744)

      Anita C.G. Chua, Carly E. Herbison, Sarah F. Drake, Ross M. Graham, John K. Olynyk and Debbie Trinder

      Article first published online: 20 DEC 2007 | DOI: 10.1002/hep.22180

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      Microtubule acetylation and stability may explain alcohol-induced alterations in hepatic protein trafficking (pages 1745–1753)

      Rohan A. Joseph, Blythe D. Shepard, George T. Kannarkat, Tara M. Rutledge, Dean J. Tuma and Pamela L. Tuma

      Article first published online: 27 DEC 2007 | DOI: 10.1002/hep.22014

  10. Meeting Report

    1. Top of page
    2. Comments from the Editors
    3. Editorial
    4. Viral Hepatitis
    5. Steatohepatitis/Metabolic Liver Disease
    6. Hepatobiliary Malignancies
    7. Autoimmune, Cholestatic and Biliary Disease
    8. Liver Failure/Cirrhosis/Portal Hypertension
    9. Liver Injury/Regeneration
    10. Liver Biology/Pathobiology
    11. Meeting Report
    12. Review
    13. Hepatology Elsewhere
    14. Correspondence
    1. You have full text access to this OnlineOpen article
    2. You have full text access to this OnlineOpen article
  11. Review

    1. Top of page
    2. Comments from the Editors
    3. Editorial
    4. Viral Hepatitis
    5. Steatohepatitis/Metabolic Liver Disease
    6. Hepatobiliary Malignancies
    7. Autoimmune, Cholestatic and Biliary Disease
    8. Liver Failure/Cirrhosis/Portal Hypertension
    9. Liver Injury/Regeneration
    10. Liver Biology/Pathobiology
    11. Meeting Report
    12. Review
    13. Hepatology Elsewhere
    14. Correspondence
    1. You have full text access to this OnlineOpen article
      Autophagy in the liver (pages 1773–1785)

      Xiao-Ming Yin, Wen-Xing Ding and Wentao Gao

      Article first published online: 7 APR 2008 | DOI: 10.1002/hep.22146

  12. Hepatology Elsewhere

    1. Top of page
    2. Comments from the Editors
    3. Editorial
    4. Viral Hepatitis
    5. Steatohepatitis/Metabolic Liver Disease
    6. Hepatobiliary Malignancies
    7. Autoimmune, Cholestatic and Biliary Disease
    8. Liver Failure/Cirrhosis/Portal Hypertension
    9. Liver Injury/Regeneration
    10. Liver Biology/Pathobiology
    11. Meeting Report
    12. Review
    13. Hepatology Elsewhere
    14. Correspondence
    1. You have full text access to this OnlineOpen article
    2. You have full text access to this OnlineOpen article
  13. Correspondence

    1. Top of page
    2. Comments from the Editors
    3. Editorial
    4. Viral Hepatitis
    5. Steatohepatitis/Metabolic Liver Disease
    6. Hepatobiliary Malignancies
    7. Autoimmune, Cholestatic and Biliary Disease
    8. Liver Failure/Cirrhosis/Portal Hypertension
    9. Liver Injury/Regeneration
    10. Liver Biology/Pathobiology
    11. Meeting Report
    12. Review
    13. Hepatology Elsewhere
    14. Correspondence
    1. You have full text access to this OnlineOpen article
    2. You have full text access to this OnlineOpen article
      Reply: (page 1791)

      Tito Livraghi

      Article first published online: 7 APR 2008 | DOI: 10.1002/hep.22281

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      Chronic genotype 4 hepatitis C (pages 1791–1792)

      Daniel F. Schafer

      Article first published online: 7 APR 2008 | DOI: 10.1002/hep.22254

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      Pegylated interferon alpha-2b plus ribavirin in patients with genotype 4 chronic hepatitis C: Some issues (pages 1792–1793)

      Ming-Lung Yu, Chia-Yen Dai, Jee-Fu Huang, Ming-Yen Hsieh and Wan-Long Chuang

      Article first published online: 19 DEC 2007 | DOI: 10.1002/hep.22171

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      Reply: (pages 1793–1794)

      Sanaa Kamal, Michelle Schardell, Samer El Kamary, Mohamed Hashem, Hoda Mansour and Amany Sayed Ibrahim

      Article first published online: 25 APR 2008 | DOI: 10.1002/hep.22290

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      HFE mutations in nonalcoholic fatty liver disease (pages 1794–1795)

      Luca Valenti, Paola Dongiovanni, Anna Ludovica Fracanzani and Silvia Fargion

      Article first published online: 25 APR 2008 | DOI: 10.1002/hep.22059

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      Reply: (pages 1795–1796)

      James E. Nelson and Kris V. Kowdley

      Article first published online: 25 APR 2008 | DOI: 10.1002/hep.22291

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      Chronic hepatitis C genotype 2 or 3 short treatment (page 1796)

      Ricardo Moreno-Otero, María Trapero and José A. Moreno-Monteagudo

      Article first published online: 25 APR 2008 | DOI: 10.1002/hep.22270

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      Reply: (pages 1797–1798)

      Marco Bertolotti, Chiara Gabbi, Claudia Anzivino, Lucia Carulli and Nicola Carulli

      Article first published online: 25 APR 2008 | DOI: 10.1002/hep.22260

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