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Hepatology

Cover image for Vol. 48 Issue 3

September 2008

Volume 48, Issue 3

Pages 697–1025

  1. Comments from the Editors

    1. Top of page
    2. Comments from the Editors
    3. Editorial
    4. Viral Hepatitis
    5. Steatohepatitis/Metabolic Liver Disease
    6. Hepatobiliary Malignancies
    7. Autoimmune, Cholestatic and Biliary Disease
    8. Liver Failure, Cirrhosis and Portal Hypertension
    9. Liver Injury and Regeneration
    10. Liver Biology and Pathobiology
    11. Meeting Report
    12. Reviews
    13. Hepatology Elsewhere
    14. Correspondence
    15. Corrections
    1. You have free access to this content
  2. Editorial

    1. Top of page
    2. Comments from the Editors
    3. Editorial
    4. Viral Hepatitis
    5. Steatohepatitis/Metabolic Liver Disease
    6. Hepatobiliary Malignancies
    7. Autoimmune, Cholestatic and Biliary Disease
    8. Liver Failure, Cirrhosis and Portal Hypertension
    9. Liver Injury and Regeneration
    10. Liver Biology and Pathobiology
    11. Meeting Report
    12. Reviews
    13. Hepatology Elsewhere
    14. Correspondence
    15. Corrections
    1. You have free access to this content
  3. Viral Hepatitis

    1. Top of page
    2. Comments from the Editors
    3. Editorial
    4. Viral Hepatitis
    5. Steatohepatitis/Metabolic Liver Disease
    6. Hepatobiliary Malignancies
    7. Autoimmune, Cholestatic and Biliary Disease
    8. Liver Failure, Cirrhosis and Portal Hypertension
    9. Liver Injury and Regeneration
    10. Liver Biology and Pathobiology
    11. Meeting Report
    12. Reviews
    13. Hepatology Elsewhere
    14. Correspondence
    15. Corrections
    1. You have free access to this content
      Specific targeting of hepatitis C virus core protein by an intracellular single-chain antibody of human origin (pages 702–712)

      Juliane Karthe, Kathi Tessmann, Jisu Li, Raiki Machida, Maaike Daleman, Dieter Häussinger and Tobias Heintges

      Article first published online: 15 APR 2008 | DOI: 10.1002/hep.22366

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      Selection of high-avidity CD8 T cells correlates with control of hepatitis C virus infection (pages 713–722)

      Bérangère Neveu, Emilie Debeaupuis, Klara Echasserieau, Béatrice le Moullac-Vaidye, Michelle Gassin, Loïg Jegou, Jérémie Decalf, Matthew Albert, Nicolas Ferry, Jérôme Gournay, Elisabeth Houssaint, Marc Bonneville and Xavier Saulquin

      Article first published online: 18 APR 2008 | DOI: 10.1002/hep.22379

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      Hepatitis C virus JFH-1 strain infection in chimpanzees is associated with low pathogenicity and emergence of an adaptive mutation (pages 732–740)

      Takanobu Kato, Youkyung Choi, Gamal Elmowalid, Ronda K. Sapp, Heidi Barth, Akihiro Furusaka, Shunji Mishiro, Takaji Wakita, Krzysztof Krawczynski and T. Jake Liang

      Article first published online: 27 MAY 2008 | DOI: 10.1002/hep.22422

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      Defective hepatitis B virus DNA is not associated with disease status but is reduced by polymerase mutations associated with drug resistance (pages 741–749)

      Scott Preiss, Margaret Littlejohn, Peter Angus, Alex Thompson, Paul Desmond, Sharon R. Lewin, Joe Sasadeusz, Gail Matthews, Gregory J. Dore, Tim Shaw, Vitini Sozzi, Lilly Yuen, George Lau, Anna Ayres, Chloe Thio, Anchalee Avihingsanon, Kiat Ruxrungtham, Stephen Locarnini and Peter A. Revill

      Article first published online: 21 APR 2008 | DOI: 10.1002/hep.22386

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      Long-term efficacy and safety of adefovir dipivoxil for the treatment of hepatitis B e antigen–positive chronic hepatitis B (pages 750–758)

      Patrick Marcellin, Ting-Tsung Chang, Seng G. Lee Lim, William Sievert, Myron Tong, Sarah Arterburn, Katyna Borroto-Esoda, David Frederick and Franck Rousseau

      Article first published online: 16 MAY 2008 | DOI: 10.1002/hep.22414

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      Programmed death 1 expression during antiviral treatment of chronic hepatitis B: Impact of hepatitis B e-antigen seroconversion (pages 759–769)

      Alexander Evans, Antonio Riva, Helen Cooksley, Sandra Phillips, Smrithi Puranik, Amit Nathwani, Sara Brett, Shilpa Chokshi and Nikolai V. Naoumov

      Article first published online: 16 MAY 2008 | DOI: 10.1002/hep.22419

  4. Steatohepatitis/Metabolic Liver Disease

    1. Top of page
    2. Comments from the Editors
    3. Editorial
    4. Viral Hepatitis
    5. Steatohepatitis/Metabolic Liver Disease
    6. Hepatobiliary Malignancies
    7. Autoimmune, Cholestatic and Biliary Disease
    8. Liver Failure, Cirrhosis and Portal Hypertension
    9. Liver Injury and Regeneration
    10. Liver Biology and Pathobiology
    11. Meeting Report
    12. Reviews
    13. Hepatology Elsewhere
    14. Correspondence
    15. Corrections
    1. You have free access to this content
      Inflammatory stress exacerbates lipid accumulation in hepatic cells and fatty livers of apolipoprotein E knockout mice (pages 770–781)

      Kun L. Ma, Xiong Z. Ruan, Stephen H. Powis, Yaxi Chen, John F. Moorhead and Zac Varghese

      Article first published online: 27 MAY 2008 | DOI: 10.1002/hep.22423

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      Nuclear receptor cofactor receptor interacting protein 140 controls hepatic triglyceride metabolism during wasting in mice (pages 782–791)

      Mauricio Berriel Diaz, Anja Krones-Herzig, Dagmar Metzger, Anja Ziegler, Alexandros Vegiopoulos, Martin Klingenspor, Karin Müller-Decker and Stephan Herzig

      Article first published online: 18 APR 2008 | DOI: 10.1002/hep.22383

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      Risk of severe liver disease in nonalcoholic fatty liver disease with normal aminotransferase levels: A role for insulin resistance and diabetes (pages 792–798)

      Anna Ludovica Fracanzani, Luca Valenti, Elisabetta Bugianesi, Marco Andreoletti, Agostino Colli, Ester Vanni, Cristina Bertelli, Erika Fatta, Daniela Bignamini, Giulio Marchesini and Silvia Fargion

      Article first published online: 30 MAY 2008 | DOI: 10.1002/hep.22429

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      Monocyte chemoattractant protein-1 secreted by adipose tissue induces direct lipid accumulation in hepatocytes (pages 799–807)

      Sophie Clément, Cristiana Juge-Aubry, Antonino Sgroi, Stéphanie Conzelmann, Valerio Pazienza, Brigitte Pittet-Cuenod, Christoph A. Meier and Francesco Negro

      Article first published online: 9 MAY 2008 | DOI: 10.1002/hep.22404

  5. Hepatobiliary Malignancies

    1. Top of page
    2. Comments from the Editors
    3. Editorial
    4. Viral Hepatitis
    5. Steatohepatitis/Metabolic Liver Disease
    6. Hepatobiliary Malignancies
    7. Autoimmune, Cholestatic and Biliary Disease
    8. Liver Failure, Cirrhosis and Portal Hypertension
    9. Liver Injury and Regeneration
    10. Liver Biology and Pathobiology
    11. Meeting Report
    12. Reviews
    13. Hepatology Elsewhere
    14. Correspondence
    15. Corrections
    1. You have free access to this content
      Hepatocellular adenomas: Magnetic resonance imaging features as a function of molecular pathological classification (pages 808–818)

      Hervé Laumonier, Paulette Bioulac-Sage, Christophe Laurent, Jessica Zucman-Rossi, Charles Balabaud and Hervé Trillaud

      Article first published online: 16 MAY 2008 | DOI: 10.1002/hep.22417

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      Excellent outcome following down-staging of hepatocellular carcinoma prior to liver transplantation: An intention-to-treat analysis (pages 819–827)

      Francis Y. Yao, Robert K. Kerlan Jr., Ryutaro Hirose, Timothy J. Davern III, Nathan M. Bass, Sandy Feng, Marion Peters, Norah Terrault, Chris E. Freise, Nancy L. Ascher and John P. Roberts

      Article first published online: 9 MAY 2008 | DOI: 10.1002/hep.22412

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      Treatment of hepatocellular carcinoma by AdAFPep/rep, AdAFPep/p53, and 5-fluorouracil in mice (pages 828–840)

      Tamotsu Sagawa, Yasuyuki Yamada, Minoru Takahashi, Yasushi Sato, Masayoshi Kobune, Rishu Takimoto, Junki Fukaura, Satoshi Iyama, Tsutomu Sato, Koji Miyanishi, Takuya Matsunaga, Tetsuji Takayama, Junji Kato, Katsunori Sasaki, Hirofumi Hamada and Yoshiro Niitsu

      Article first published online: 28 AUG 2008 | DOI: 10.1002/hep.22420

  6. Autoimmune, Cholestatic and Biliary Disease

    1. Top of page
    2. Comments from the Editors
    3. Editorial
    4. Viral Hepatitis
    5. Steatohepatitis/Metabolic Liver Disease
    6. Hepatobiliary Malignancies
    7. Autoimmune, Cholestatic and Biliary Disease
    8. Liver Failure, Cirrhosis and Portal Hypertension
    9. Liver Injury and Regeneration
    10. Liver Biology and Pathobiology
    11. Meeting Report
    12. Reviews
    13. Hepatology Elsewhere
    14. Correspondence
    15. Corrections
    1. You have free access to this content
      Natural killer T cell dysfunction in CD39-null mice protects against concanavalin A–induced hepatitis (pages 841–852)

      Guido Beldi, Yan Wu, Yara Banz, Michael Nowak, Lindsay Miller, Keiichi Enjyoji, Arvand Haschemi, Gennady G. Yegutkin, Daniel Candinas, Mark Exley and Simon C. Robson

      Article first published online: 2 MAY 2008 | DOI: 10.1002/hep.22401

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      Single-nucleotide polymorphism analysis of the multidrug resistance protein 3 gene for the detection of clinical progression in Japanese patients with primary biliary cirrhosis (pages 853–862)

      Yuki Ohishi, Minoru Nakamura, Naomi Iio, Shingo Higa, Mao Inayoshi, Yoshihiro Aiba, Atsumasa Komori, Katsuhisa Omagari, Hiromi Ishibashi and Kazuhiro Tsukamoto

      Article first published online: 18 APR 2008 | DOI: 10.1002/hep.22382

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      Evaluation of risk factors in the development of hepatocellular carcinoma in autoimmune hepatitis: Implications for follow-up and screening (pages 863–870)

      Andrew D. Yeoman, Thawab Al-Chalabi, John B. Karani, Alberto Quaglia, John Devlin, Giorgina Mieli-Vergani, Adrian Bomford, John G. O'Grady, Phillip M. Harrison and Michael A. Heneghan

      Article first published online: 27 MAY 2008 | DOI: 10.1002/hep.22432

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      Biochemical response to ursodeoxycholic acid and long-term prognosis in primary biliary cirrhosis (pages 871–877)

      Christophe Corpechot, Ludovico Abenavoli, Nabila Rabahi, Yves Chrétien, Tony Andréani, Catherine Johanet, Olivier Chazouillères and Raoul Poupon

      Article first published online: 30 MAY 2008 | DOI: 10.1002/hep.22428

  7. Liver Failure, Cirrhosis and Portal Hypertension

    1. Top of page
    2. Comments from the Editors
    3. Editorial
    4. Viral Hepatitis
    5. Steatohepatitis/Metabolic Liver Disease
    6. Hepatobiliary Malignancies
    7. Autoimmune, Cholestatic and Biliary Disease
    8. Liver Failure, Cirrhosis and Portal Hypertension
    9. Liver Injury and Regeneration
    10. Liver Biology and Pathobiology
    11. Meeting Report
    12. Reviews
    13. Hepatology Elsewhere
    14. Correspondence
    15. Corrections
    1. You have free access to this content
      Long-term outcome of human leukocyte antigen mismatching in liver transplantation: Results of the national institute of diabetes and digestive and kidney diseases liver transplantation database (pages 878–888)

      Vijayan Balan, Kris Ruppert, A. Jake Demetris, Tatiana Ledneva, Rene J. Duquesnoy, Katherine M. Detre, Yuling L. Wei, Jorge Rakela, Daniel F. Schafer, John P. Roberts, James E. Everhart and Russell H. Wiesner

      Article first published online: 30 MAY 2008 | DOI: 10.1002/hep.22435

  8. Liver Injury and Regeneration

    1. Top of page
    2. Comments from the Editors
    3. Editorial
    4. Viral Hepatitis
    5. Steatohepatitis/Metabolic Liver Disease
    6. Hepatobiliary Malignancies
    7. Autoimmune, Cholestatic and Biliary Disease
    8. Liver Failure, Cirrhosis and Portal Hypertension
    9. Liver Injury and Regeneration
    10. Liver Biology and Pathobiology
    11. Meeting Report
    12. Reviews
    13. Hepatology Elsewhere
    14. Correspondence
    15. Corrections
    1. You have free access to this content
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    3. You have free access to this content
  9. Liver Biology and Pathobiology

    1. Top of page
    2. Comments from the Editors
    3. Editorial
    4. Viral Hepatitis
    5. Steatohepatitis/Metabolic Liver Disease
    6. Hepatobiliary Malignancies
    7. Autoimmune, Cholestatic and Biliary Disease
    8. Liver Failure, Cirrhosis and Portal Hypertension
    9. Liver Injury and Regeneration
    10. Liver Biology and Pathobiology
    11. Meeting Report
    12. Reviews
    13. Hepatology Elsewhere
    14. Correspondence
    15. Corrections
    1. You have free access to this content
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      “Toxic memory” via chaperone modification is a potential mechanism for rapid mallory-denk body reinduction (pages 931–942)

      Pavel Strnad, Guo-Zhong Tao, Phillip So, Kenneth Lau, Jim Schilling, Yuquan Wei, Jian Liao and M. Bishr Omary

      Article first published online: 27 MAY 2008 | DOI: 10.1002/hep.22430

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    4. You have full text access to this OnlineOpen article
      Significant gene expression differences in histologically “Normal” liver biopsies: Implications for control tissue (pages 953–962)

      Tarik Asselah, Ivan Bièche, Ingrid Laurendeau, Michelle Martinot-Peignoux, Valerie Paradis, Dominique Vidaud, Dominique-Charles Valla, Pierre Bedossa, Patrick Marcellin and Michel Vidaud

      Article first published online: 9 MAY 2008 | DOI: 10.1002/hep.22411

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      Activation of hepatic stellate cells after phagocytosis of lymphocytes: A novel pathway of fibrogenesis (pages 963–977)

      Nidal Muhanna, Sarit Doron, Ori Wald, Amjad Horani, Ahmed Eid, Orit Pappo, Scott L. Friedman and Rifaat Safadi

      Article first published online: 16 MAY 2008 | DOI: 10.1002/hep.22413

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      Mechanism of T cell tolerance induction by murine hepatic Kupffer cells (pages 978–990)

      Qiang You, Linling Cheng, Ross M. Kedl and Cynthia Ju

      Article first published online: 2 MAY 2008 | DOI: 10.1002/hep.22395

  10. Meeting Report

    1. Top of page
    2. Comments from the Editors
    3. Editorial
    4. Viral Hepatitis
    5. Steatohepatitis/Metabolic Liver Disease
    6. Hepatobiliary Malignancies
    7. Autoimmune, Cholestatic and Biliary Disease
    8. Liver Failure, Cirrhosis and Portal Hypertension
    9. Liver Injury and Regeneration
    10. Liver Biology and Pathobiology
    11. Meeting Report
    12. Reviews
    13. Hepatology Elsewhere
    14. Correspondence
    15. Corrections
    1. You have free access to this content
      Hereditary hemochromatosis in the post-HFE era (pages 991–1001)

      John K. Olynyk, Debbie Trinder, Grant A. Ramm, Robert S. Britton and Bruce R. Bacon

      Article first published online: 16 JUL 2008 | DOI: 10.1002/hep.22507

  11. Reviews

    1. Top of page
    2. Comments from the Editors
    3. Editorial
    4. Viral Hepatitis
    5. Steatohepatitis/Metabolic Liver Disease
    6. Hepatobiliary Malignancies
    7. Autoimmune, Cholestatic and Biliary Disease
    8. Liver Failure, Cirrhosis and Portal Hypertension
    9. Liver Injury and Regeneration
    10. Liver Biology and Pathobiology
    11. Meeting Report
    12. Reviews
    13. Hepatology Elsewhere
    14. Correspondence
    15. Corrections
    1. You have free access to this content
  12. Hepatology Elsewhere

    1. Top of page
    2. Comments from the Editors
    3. Editorial
    4. Viral Hepatitis
    5. Steatohepatitis/Metabolic Liver Disease
    6. Hepatobiliary Malignancies
    7. Autoimmune, Cholestatic and Biliary Disease
    8. Liver Failure, Cirrhosis and Portal Hypertension
    9. Liver Injury and Regeneration
    10. Liver Biology and Pathobiology
    11. Meeting Report
    12. Reviews
    13. Hepatology Elsewhere
    14. Correspondence
    15. Corrections
    1. You have free access to this content
    2. You have free access to this content
  13. Correspondence

    1. Top of page
    2. Comments from the Editors
    3. Editorial
    4. Viral Hepatitis
    5. Steatohepatitis/Metabolic Liver Disease
    6. Hepatobiliary Malignancies
    7. Autoimmune, Cholestatic and Biliary Disease
    8. Liver Failure, Cirrhosis and Portal Hypertension
    9. Liver Injury and Regeneration
    10. Liver Biology and Pathobiology
    11. Meeting Report
    12. Reviews
    13. Hepatology Elsewhere
    14. Correspondence
    15. Corrections
    1. You have free access to this content
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      Reply: (pages 1016–1017)

      Nathan A. Johnson, Toos Sachinwalla and Jacob George

      Article first published online: 8 JUL 2008 | DOI: 10.1002/hep.22494

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      Reply: (pages 1017–1018)

      Joel G. Fletcher, Luis S. Guimaraes, Jeff L. Fidler and Patrick S. Kamath

      Article first published online: 28 AUG 2008 | DOI: 10.1002/hep.22477

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      Reply: (page 1019)

      Muhammad Y. Sheikh

      Article first published online: 28 AUG 2008 | DOI: 10.1002/hep.22455

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      Reply: (pages 1020–1021)

      Alessandra Mangia and Angelo Andriulli

      Article first published online: 28 AUG 2008 | DOI: 10.1002/hep.22456

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      Reply: (page 1022)

      Chia-Ming Chu

      Article first published online: 16 JUL 2008 | DOI: 10.1002/hep.22501

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      Reply: (pages 1023–1024)

      Winston Dunn and Jeffrey B. Schwimmer

      Article first published online: 9 JUL 2008 | DOI: 10.1002/hep.22502

  14. Corrections

    1. Top of page
    2. Comments from the Editors
    3. Editorial
    4. Viral Hepatitis
    5. Steatohepatitis/Metabolic Liver Disease
    6. Hepatobiliary Malignancies
    7. Autoimmune, Cholestatic and Biliary Disease
    8. Liver Failure, Cirrhosis and Portal Hypertension
    9. Liver Injury and Regeneration
    10. Liver Biology and Pathobiology
    11. Meeting Report
    12. Reviews
    13. Hepatology Elsewhere
    14. Correspondence
    15. Corrections
    1. You have free access to this content
      Correction (page 1025)

      Article first published online: 7 AUG 2008 | DOI: 10.1002/hep.22511

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      Correction (page 1025)

      Stephen J. Polyak, Chihiro Morishima and Roy Hawke

      Article first published online: 28 AUG 2008 | DOI: 10.1002/hep.22539

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