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Hepatology

Cover image for Hepatology

January 2009

Volume 49, Issue 1

Pages 1–338

  1. Obituary

    1. Top of page
    2. Obituary
    3. Comments from the Editors
    4. Editorials
    5. Viral Hepatitis
    6. Steatohepatitis/Metabolic Liver Disease
    7. Hepatobiliary Malignancies
    8. Autoimmune, Cholestatic and Biliary Disease
    9. Liver Failure/Cirrhosis/Portal Hypertension
    10. Liver Injury/Regeneration
    11. Liver Biology/Pathobiology
    12. Reviews
    13. Hepatology Elsewhere
    14. Image of the Month
    15. Correspondence
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      In memoriam: Dr. Herbert Falk (1924-2008) (pages 1–3)

      Alan F. Hofmann

      Version of Record online: 19 NOV 2008 | DOI: 10.1002/hep.22746

  2. Comments from the Editors

    1. Top of page
    2. Obituary
    3. Comments from the Editors
    4. Editorials
    5. Viral Hepatitis
    6. Steatohepatitis/Metabolic Liver Disease
    7. Hepatobiliary Malignancies
    8. Autoimmune, Cholestatic and Biliary Disease
    9. Liver Failure/Cirrhosis/Portal Hypertension
    10. Liver Injury/Regeneration
    11. Liver Biology/Pathobiology
    12. Reviews
    13. Hepatology Elsewhere
    14. Image of the Month
    15. Correspondence
    1. You have free access to this content
  3. Editorials

    1. Top of page
    2. Obituary
    3. Comments from the Editors
    4. Editorials
    5. Viral Hepatitis
    6. Steatohepatitis/Metabolic Liver Disease
    7. Hepatobiliary Malignancies
    8. Autoimmune, Cholestatic and Biliary Disease
    9. Liver Failure/Cirrhosis/Portal Hypertension
    10. Liver Injury/Regeneration
    11. Liver Biology/Pathobiology
    12. Reviews
    13. Hepatology Elsewhere
    14. Image of the Month
    15. Correspondence
    1. You have free access to this content
    2. You have free access to this content
  4. Viral Hepatitis

    1. Top of page
    2. Obituary
    3. Comments from the Editors
    4. Editorials
    5. Viral Hepatitis
    6. Steatohepatitis/Metabolic Liver Disease
    7. Hepatobiliary Malignancies
    8. Autoimmune, Cholestatic and Biliary Disease
    9. Liver Failure/Cirrhosis/Portal Hypertension
    10. Liver Injury/Regeneration
    11. Liver Biology/Pathobiology
    12. Reviews
    13. Hepatology Elsewhere
    14. Image of the Month
    15. Correspondence
    1. You have free access to this content
      Natural killer cell function is intact after direct exposure to infectious hepatitis C virions (pages 12–21)

      Joo Chun Yoon, Masaaki Shiina, Golo Ahlenstiel and Barbara Rehermann

      Version of Record online: 9 SEP 2008 | DOI: 10.1002/hep.22624

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      Randomized trial comparing pegylated interferon α-2b versus pegylated interferon α-2a, both plus ribavirin, to treat chronic hepatitis C in human immunodeficiency virus patients (pages 22–31)

      Montserrat Laguno, Carmen Cifuentes, Javier Murillas, Sergio Veloso, Maria Larrousse, Antoni Payeras, Lucia Bonet, Francese Vidal, Ana Milinkovic, Antoni Bassa, Concha Villalonga, Iñaki Pérez, Cristina Tural, Maria Martínez-Rebollar, Marta Calvo, Jose Luis Blanco, Estaban Martínez, Jose M. Sánchez-Tapias, Jose M. Gatell and Jose Mallolas

      Version of Record online: 9 SEP 2008 | DOI: 10.1002/hep.22598

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      Modeling complex decay profiles of hepatitis B virus during antiviral therapy (pages 32–38)

      Harel Dahari, Emi Shudo, Ruy M. Ribeiro and Alan S. Perelson

      Version of Record online: 19 AUG 2008 | DOI: 10.1002/hep.22586

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      Llama-derived single-domain intrabodies inhibit secretion of hepatitis B virions in mice (pages 39–49)

      Benedikte Serruys, Freya Van Houtte, Phebe Verbrugghe, Geert Leroux-Roels and Peter Vanlandschoot

      Version of Record online: 10 DEC 2008 | DOI: 10.1002/hep.22609

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      Complex dynamics of hepatitis B virus resistance to adefovir (pages 50–59)

      Coralie Pallier, Christophe Rodriguez, Rozenn Brillet, Patrice Nordmann, Christophe Hézode and Jean-Michel Pawlotsky

      Version of Record online: 18 SEP 2008 | DOI: 10.1002/hep.22634

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      Hepatitis B virus X protein sensitizes cells to starvation-induced autophagy via up-regulation of beclin 1 expression (pages 60–71)

      Hong Tang, Liang Da, Yi Mao, Ying Li, Dong Li, Zhenhua Xu, Feng Li, Yifei Wang, Pierre Tiollais, Tsaiping Li and Mujun Zhao

      Version of Record online: 14 AUG 2008 | DOI: 10.1002/hep.22581

      Corrected by:

      Correction: Correction

      Vol. 52, Issue 3, 1176, Version of Record online: 27 AUG 2010

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      Early hepatitis B virus DNA reduction in hepatitis B e antigen–positive patients with chronic hepatitis B: A randomized international study of entecavir versus adefovir (pages 72–79)

      Nancy Leung, Cheng-Yuan Peng, Hie-Won Hann, Jose Sollano, Judy Lao-Tan, Chao-Wei Hsu, Laurentius Lesmana, Man-Fung Yuen, Lennox Jeffers, Morris Sherman, Albert Min, Kimberly Mencarini, Ulysses Diva, Anne Cross, Richard Wilber and Juan Lopez-Talavera

      Version of Record online: 26 SEP 2008 | DOI: 10.1002/hep.22658

  5. Steatohepatitis/Metabolic Liver Disease

    1. Top of page
    2. Obituary
    3. Comments from the Editors
    4. Editorials
    5. Viral Hepatitis
    6. Steatohepatitis/Metabolic Liver Disease
    7. Hepatobiliary Malignancies
    8. Autoimmune, Cholestatic and Biliary Disease
    9. Liver Failure/Cirrhosis/Portal Hypertension
    10. Liver Injury/Regeneration
    11. Liver Biology/Pathobiology
    12. Reviews
    13. Hepatology Elsewhere
    14. Image of the Month
    15. Correspondence
    1. You have free access to this content
      Orlistat for overweight subjects with nonalcoholic steatohepatitis: A randomized, prospective trial (pages 80–86)

      Stephen A. Harrison, Will Fecht, Elizabeth M. Brunt and Brent A. Neuschwander-Tetri

      Version of Record online: 22 OCT 2008 | DOI: 10.1002/hep.22575

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      Differential effects of JNK1 and JNK2 inhibition on murine steatohepatitis and insulin resistance (pages 87–96)

      Rajat Singh, Yongjun Wang, Youqing Xiang, Kathryn E. Tanaka, William A. Gaarde and Mark J. Czaja

      Version of Record online: 14 AUG 2008 | DOI: 10.1002/hep.22578

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      Diagnostic and prognostic values of noninvasive biomarkers of fibrosis in patients with alcoholic liver disease (pages 97–105)

      Sylvie Naveau, Guillaume Gaudé, Amani Asnacios, Hélène Agostini, Annie Abella, Nadège Barri-Ova, Barbara Dauvois, Sophie Prévot, Yen Ngo, Mona Munteanu, Axel Balian, Micheline Njiké-Nakseu, Gabriel Perlemuter and Thierry Poynard

      Version of Record online: 14 AUG 2008 | DOI: 10.1002/hep.22576

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      Atorvastatin prevents carbohydrate response element binding protein activation in the fructose-fed rat by activating protein kinase A (pages 106–115)

      Ricardo Rodríguez-Calvo, Emma Barroso, Lucía Serrano, Teresa Coll, Rosa M. Sánchez, Manuel Merlos, Xavier Palomer, Juan C. Laguna and Manuel Vázquez-Carrera

      Version of Record online: 5 AUG 2008 | DOI: 10.1002/hep.22570

  6. Hepatobiliary Malignancies

    1. Top of page
    2. Obituary
    3. Comments from the Editors
    4. Editorials
    5. Viral Hepatitis
    6. Steatohepatitis/Metabolic Liver Disease
    7. Hepatobiliary Malignancies
    8. Autoimmune, Cholestatic and Biliary Disease
    9. Liver Failure/Cirrhosis/Portal Hypertension
    10. Liver Injury/Regeneration
    11. Liver Biology/Pathobiology
    12. Reviews
    13. Hepatology Elsewhere
    14. Image of the Month
    15. Correspondence
    1. You have free access to this content
      Risk of hepatobiliary and pancreatic cancers after hepatitis C virus infection: A population-based study of U.S. veterans (pages 116–123)

      Hashem B. El-Serag, Eric A. Engels, Ola Landgren, Elizabeth Chiao, Louise Henderson, Harshinie C. Amaratunge and Thomas P. Giordano

      Version of Record online: 2 SEP 2008 | DOI: 10.1002/hep.22606

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      A phase II study of adoptive immunotherapy using dendritic cells pulsed with tumor lysate in patients with hepatocellular carcinoma (pages 124–132)

      Daniel H. Palmer, Rachel S. Midgley, Noweeda Mirza, Elizabeth E. Torr, Forhad Ahmed, Jane C. Steele, Neil M. Steven, David J. Kerr, Lawrence S. Young and David H. Adams

      Version of Record online: 3 NOV 2008 | DOI: 10.1002/hep.22626

  7. Autoimmune, Cholestatic and Biliary Disease

    1. Top of page
    2. Obituary
    3. Comments from the Editors
    4. Editorials
    5. Viral Hepatitis
    6. Steatohepatitis/Metabolic Liver Disease
    7. Hepatobiliary Malignancies
    8. Autoimmune, Cholestatic and Biliary Disease
    9. Liver Failure/Cirrhosis/Portal Hypertension
    10. Liver Injury/Regeneration
    11. Liver Biology/Pathobiology
    12. Reviews
    13. Hepatology Elsewhere
    14. Image of the Month
    15. Correspondence
    1. You have free access to this content
      Differential mechanisms in the pathogenesis of autoimmune cholangitis versus inflammatory bowel disease in interleukin-2Rα−/− mice (pages 133–140)

      Willy Hsu, Weici Zhang, Koichi Tsuneyama, Yuki Moritoki, William M. Ridgway, Aftab A. Ansari, Ross L. Coppel, Zhe-Xiong Lian, Ian Mackay and M. Eric Gershwin

      Version of Record online: 22 AUG 2008 | DOI: 10.1002/hep.22591

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      Cystathionine β-synthase as a carbon monoxide–sensitive regulator of bile excretion (pages 141–150)

      Tsunehiro Shintani, Takuya Iwabuchi, Tomoyoshi Soga, Yuichiro Kato, Takehiro Yamamoto, Naoharu Takano, Takako Hishiki, Yuki Ueno, Satsuki Ikeda, Tadayuki Sakuragawa, Kazuo Ishikawa, Nobuhito Goda, Yuko Kitagawa, Mayumi Kajimura, Kenji Matsumoto and Makoto Suematsu

      Version of Record online: 2 SEP 2008 | DOI: 10.1002/hep.22604

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      Low retinol levels differentially modulate bile salt–induced expression of human and mouse hepatic bile salt transporters (pages 151–159)

      Martijn O. Hoeke, Jacqueline R.M. Plass, Janette Heegsma, Mariska Geuken, Duncan van Rijsbergen, Julius F.W. Baller, Folkert Kuipers, Han Moshage, Peter L.M. Jansen and Klaas Nico Faber

      Version of Record online: 26 SEP 2008 | DOI: 10.1002/hep.22661

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      The cAMP effectors Epac and protein kinase a (PKA) are involved in the hepatic cystogenesis of an animal model of autosomal recessive polycystic kidney disease (ARPKD) (pages 160–174)

      Jesús M. Banales, Tatyana V. Masyuk, Sergio A. Gradilone, Anatoliy I. Masyuk, Juan F. Medina and Nicholas F. LaRusso

      Version of Record online: 19 SEP 2008 | DOI: 10.1002/hep.22636

  8. Liver Failure/Cirrhosis/Portal Hypertension

    1. Top of page
    2. Obituary
    3. Comments from the Editors
    4. Editorials
    5. Viral Hepatitis
    6. Steatohepatitis/Metabolic Liver Disease
    7. Hepatobiliary Malignancies
    8. Autoimmune, Cholestatic and Biliary Disease
    9. Liver Failure/Cirrhosis/Portal Hypertension
    10. Liver Injury/Regeneration
    11. Liver Biology/Pathobiology
    12. Reviews
    13. Hepatology Elsewhere
    14. Image of the Month
    15. Correspondence
    1. You have free access to this content
      Ex vivo effects of high-density lipoprotein exposure on the lipopolysaccharide-induced inflammatory response in patients with severe cirrhosis (pages 175–184)

      Arnaud Galbois, Dominique Thabut, Khalid A. Tazi, Marika Rudler, Morvarid Shir Mohammadi, Dominique Bonnefont-Rousselot, Hind Bennani, Annie Bezeaud, Zera Tellier, Cécile Guichard, Nicolas Coant, Eric Ogier-Denis, Richard Moreau and Didier Lebrec

      Version of Record online: 14 AUG 2008 | DOI: 10.1002/hep.22582

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      Adenosine induces loss of actin stress fibers and inhibits contraction in hepatic stellate cells via Rho inhibition (pages 185–194)

      Muhammad A. Sohail, Ardeshir Z. Hashmi, Wyel Hakim, Azuma Watanabe, Alexander Zipprich, Roberto J. Groszmann, Jonathan A. Dranoff, Natalie J. Torok and Wajahat Z. Mehal

      Version of Record online: 9 OCT 2008 | DOI: 10.1002/hep.22589

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      Insulin resistance is a risk factor for esophageal varices in hepatitis C virus cirrhosis (pages 195–203)

      Calogero Cammà, Salvatore Petta, Vito Di Marco, Fabrizio Bronte, Stefania Ciminnisi, Giusalba Licata, Sergio Peralta, Fabio Simone, Giulio Marchesini and Antonio Craxì

      Version of Record online: 26 SEP 2008 | DOI: 10.1002/hep.22655

  9. Liver Injury/Regeneration

    1. Top of page
    2. Obituary
    3. Comments from the Editors
    4. Editorials
    5. Viral Hepatitis
    6. Steatohepatitis/Metabolic Liver Disease
    7. Hepatobiliary Malignancies
    8. Autoimmune, Cholestatic and Biliary Disease
    9. Liver Failure/Cirrhosis/Portal Hypertension
    10. Liver Injury/Regeneration
    11. Liver Biology/Pathobiology
    12. Reviews
    13. Hepatology Elsewhere
    14. Image of the Month
    15. Correspondence
    1. You have free access to this content
    2. You have free access to this content
      Effect of polyI:C cotreatment on halothane-induced liver injury in mice (pages 215–226)

      Linling Cheng, Qiang You, Hao Yin, Michael Holt, Christopher Franklin and Cynthia Ju

      Version of Record online: 19 AUG 2008 | DOI: 10.1002/hep.22585

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      Lymphotoxin-β receptor signaling regulates hepatic stellate cell function and wound healing in a murine model of chronic liver injury (pages 227–239)

      Richard G. Ruddell, Belinda Knight, Janina E. E. Tirnitz-Parker, Barbara Akhurst, Lesa Summerville, V. Nathan Subramaniam, John K. Olynyk and Grant A. Ramm

      Version of Record online: 22 AUG 2008 | DOI: 10.1002/hep.22597

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      Hepatocyte-specific deletion of Cdc42 results in delayed liver regeneration after partial hepatectomy in mice (pages 240–249)

      Haixin Yuan, Hong Zhang, Xunwei Wu, Zhe Zhang, Dan Du, Wenchao Zhou, Shuhua Zhou, Cord Brakebusch and Zhengjun Chen

      Version of Record online: 10 DEC 2008 | DOI: 10.1002/hep.22610

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      Telithromycin-associated hepatotoxicity: Clinical spectrum and causality assessment of 42 cases (pages 250–257)

      Allen D. Brinker, Ronald T. Wassel, Jenna Lyndly, Jose Serrano, Mark Avigan, William M. Lee and Leonard B. Seeff

      Version of Record online: 9 DEC 2008 | DOI: 10.1002/hep.22620

  10. Liver Biology/Pathobiology

    1. Top of page
    2. Obituary
    3. Comments from the Editors
    4. Editorials
    5. Viral Hepatitis
    6. Steatohepatitis/Metabolic Liver Disease
    7. Hepatobiliary Malignancies
    8. Autoimmune, Cholestatic and Biliary Disease
    9. Liver Failure/Cirrhosis/Portal Hypertension
    10. Liver Injury/Regeneration
    11. Liver Biology/Pathobiology
    12. Reviews
    13. Hepatology Elsewhere
    14. Image of the Month
    15. Correspondence
    1. You have free access to this content
      Hepatic irradiation augments engraftment of donor cells following hepatocyte transplantation (pages 258–267)

      Kosho Yamanouchi, Hongchao Zhou, Namita Roy-Chowdhury, Frank Macaluso, Liping Liu, Toshiyuki Yamamoto, Govardhana Rao Yannam, Charles Enke, Timothy D. Solberg, Anthony B. Adelson, Jeffrey L. Platt, Ira J. Fox, Jayanta Roy-Chowdhury and Chandan Guha

      Version of Record online: 8 AUG 2008 | DOI: 10.1002/hep.22573

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      Disruption of the transcription factor recombination signal-binding protein-Jκ (RBP-J) leads to veno-occlusive disease and interfered liver regeneration in mice (pages 268–277)

      Lin Wang, Chun-Mei Wang, Li-Hong Hou, Guo-Rui Dou, Yao-Chun Wang, Xing-Bin Hu, Fei He, Fan Feng, Hong-Wei Zhang, Ying-Min Liang, Ke-Feng Dou and Hua Han

      Version of Record online: 14 AUG 2008 | DOI: 10.1002/hep.22579

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      Competitive inhibition of leptin signaling results in amelioration of liver fibrosis through modulation of stellate cell function (pages 278–286)

      Eran Elinav, Mohammad Ali, Rafi Bruck, Eli Brazowski, Adam Phillips, Yami Shapira, Meirav Katz, Gila Solomon, Zamir Halpern and Arieh Gertler

      Version of Record online: 19 AUG 2008 | DOI: 10.1002/hep.22584

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      The pathogen receptor liver and lymph node sinusoidal endotelial cell C-type lectin is expressed in human Kupffer cells and regulated by PU.1 (pages 287–296)

      Ángeles Domínguez-Soto, Laura Aragoneses-Fenoll, Fernando Gómez-Aguado, María Teresa Corcuera, Joan Clária, Carmelo García-Monzón, Matilde Bustos and Angel L. Corbí

      Version of Record online: 18 DEC 2008 | DOI: 10.1002/hep.22678

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  11. Reviews

    1. Top of page
    2. Obituary
    3. Comments from the Editors
    4. Editorials
    5. Viral Hepatitis
    6. Steatohepatitis/Metabolic Liver Disease
    7. Hepatobiliary Malignancies
    8. Autoimmune, Cholestatic and Biliary Disease
    9. Liver Failure/Cirrhosis/Portal Hypertension
    10. Liver Injury/Regeneration
    11. Liver Biology/Pathobiology
    12. Reviews
    13. Hepatology Elsewhere
    14. Image of the Month
    15. Correspondence
    1. You have free access to this content
    2. You have free access to this content
      Liver stem cells and hepatocellular carcinoma (pages 318–329)

      Lopa Mishra, Tanuj Banker, Joseph Murray, Stephen Byers, Arun Thenappan, Aiwu Ruth He, Kirti Shetty, Lynt Johnson and E. P. Reddy

      Version of Record online: 24 OCT 2008 | DOI: 10.1002/hep.22704

  12. Hepatology Elsewhere

    1. Top of page
    2. Obituary
    3. Comments from the Editors
    4. Editorials
    5. Viral Hepatitis
    6. Steatohepatitis/Metabolic Liver Disease
    7. Hepatobiliary Malignancies
    8. Autoimmune, Cholestatic and Biliary Disease
    9. Liver Failure/Cirrhosis/Portal Hypertension
    10. Liver Injury/Regeneration
    11. Liver Biology/Pathobiology
    12. Reviews
    13. Hepatology Elsewhere
    14. Image of the Month
    15. Correspondence
    1. You have free access to this content
      Improve organ health by chewing up old proteins? (pages 330–332)

      Luis Miguel Guachalla and K. Lenhard Rudolph

      Version of Record online: 13 NOV 2008 | DOI: 10.1002/hep.22738

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  13. Image of the Month

    1. Top of page
    2. Obituary
    3. Comments from the Editors
    4. Editorials
    5. Viral Hepatitis
    6. Steatohepatitis/Metabolic Liver Disease
    7. Hepatobiliary Malignancies
    8. Autoimmune, Cholestatic and Biliary Disease
    9. Liver Failure/Cirrhosis/Portal Hypertension
    10. Liver Injury/Regeneration
    11. Liver Biology/Pathobiology
    12. Reviews
    13. Hepatology Elsewhere
    14. Image of the Month
    15. Correspondence
    1. You have free access to this content
  14. Correspondence

    1. Top of page
    2. Obituary
    3. Comments from the Editors
    4. Editorials
    5. Viral Hepatitis
    6. Steatohepatitis/Metabolic Liver Disease
    7. Hepatobiliary Malignancies
    8. Autoimmune, Cholestatic and Biliary Disease
    9. Liver Failure/Cirrhosis/Portal Hypertension
    10. Liver Injury/Regeneration
    11. Liver Biology/Pathobiology
    12. Reviews
    13. Hepatology Elsewhere
    14. Image of the Month
    15. Correspondence
    1. You have free access to this content
      Misleading figures on trends in mortality from hepatocellular carcinoma in europe (page 336)

      Ann-Sofi Duberg and Rolf Hultcrantz

      Version of Record online: 9 OCT 2008 | DOI: 10.1002/hep.22671

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      Reply: (pages 336–337)

      Cristina Bosetti, Fabio Levi, Paolo Boffetta, Franca Lucchini, Eva Negri and Carlo La Vecchia

      Version of Record online: 13 NOV 2008 | DOI: 10.1002/hep.22690

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      Comment on biochemical response to ursodeoxycholic acid and long-term prognosis in primary biliary cirrhosis (pages 337–338)

      Lucy J. Walker, Julia Newton, David E. J. Jones and Margaret F. Bassendine

      Version of Record online: 13 NOV 2008 | DOI: 10.1002/hep.22670

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      Reply: (page 338)

      Raoul Poupon, Olivier Chazouilleres and Christophe Corpechot

      Version of Record online: 13 NOV 2008 | DOI: 10.1002/hep.22689

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