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Hepatology

Cover image for Hepatology

August 2009

Volume 50, Issue 2

Pages 333–660

  1. Master's Perspective

    1. Top of page
    2. Master's Perspective
    3. Comments from the Editors
    4. Editorials
    5. Viral Hepatitis
    6. Steatohepatitis/Metabolic Liver Disease
    7. Hepatobiliary Malignancies
    8. Autoimmune, Cholestatic and Biliary Disease
    9. Liver Failure/Cirrhosis/Portal Hypertension
    10. Liver Injury/Regeneration
    11. Liver Biology/Pathobiology
    12. Reviews
    13. Hepatology Elsewhere
    14. Image of the Month
    15. Correspondence
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  2. Comments from the Editors

    1. Top of page
    2. Master's Perspective
    3. Comments from the Editors
    4. Editorials
    5. Viral Hepatitis
    6. Steatohepatitis/Metabolic Liver Disease
    7. Hepatobiliary Malignancies
    8. Autoimmune, Cholestatic and Biliary Disease
    9. Liver Failure/Cirrhosis/Portal Hypertension
    10. Liver Injury/Regeneration
    11. Liver Biology/Pathobiology
    12. Reviews
    13. Hepatology Elsewhere
    14. Image of the Month
    15. Correspondence
    1. You have free access to this content
  3. Editorials

    1. Top of page
    2. Master's Perspective
    3. Comments from the Editors
    4. Editorials
    5. Viral Hepatitis
    6. Steatohepatitis/Metabolic Liver Disease
    7. Hepatobiliary Malignancies
    8. Autoimmune, Cholestatic and Biliary Disease
    9. Liver Failure/Cirrhosis/Portal Hypertension
    10. Liver Injury/Regeneration
    11. Liver Biology/Pathobiology
    12. Reviews
    13. Hepatology Elsewhere
    14. Image of the Month
    15. Correspondence
    1. You have free access to this content
    2. You have free access to this content
    3. You have free access to this content
    4. You have free access to this content
  4. Viral Hepatitis

    1. Top of page
    2. Master's Perspective
    3. Comments from the Editors
    4. Editorials
    5. Viral Hepatitis
    6. Steatohepatitis/Metabolic Liver Disease
    7. Hepatobiliary Malignancies
    8. Autoimmune, Cholestatic and Biliary Disease
    9. Liver Failure/Cirrhosis/Portal Hypertension
    10. Liver Injury/Regeneration
    11. Liver Biology/Pathobiology
    12. Reviews
    13. Hepatology Elsewhere
    14. Image of the Month
    15. Correspondence
    1. You have free access to this content
      Outcomes of a patient-to-patient outbreak of genotype 3a hepatitis C (pages 361–368)

      Mark E. Mailliard, Mary E. Capadano, Matthew J. Hrnicek, Richard K. Gilroy and James M. Gulizia

      Article first published online: 6 APR 2009 | DOI: 10.1002/hep.22992

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      Individualized treatment strategy according to early viral kinetics in hepatitis C virus type 1–infected patients (pages 369–377)

      Thomas Berg, Viola Weich, Gerlinde Teuber, Hartwig Klinker, Bernd Möller, Jens Rasenack, Holger Hinrichsen, Tilman Gerlach, Ulrich Spengler, Peter Buggisch, Heike Balk, Myrga Zankel, Konrad Neumann, Christoph Sarrazin and Stefan Zeuzem

      Article first published online: 6 APR 2009 | DOI: 10.1002/hep.22991

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      Proteomics analysis of mitochondrial proteins reveals overexpression of a mitochondrial protein chaperon, prohibitin, in cells expressing hepatitis C virus core protein (pages 378–386)

      Takeya Tsutsumi, Mami Matsuda, Hideki Aizaki, Kyoji Moriya, Hideyuki Miyoshi, Hajime Fujie, Yoshizumi Shintani, Hiroshi Yotsuyanagi, Tatsuo Miyamura, Tetsuro Suzuki and Kazuhiko Koike

      Article first published online: 9 JUL 2009 | DOI: 10.1002/hep.22998

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      Effect of hepatitis C virus and its treatment on survival (pages 387–392)

      Adeel A. Butt, Xiaoqiang Wang and Charity G. Moore

      Article first published online: 9 JUL 2009 | DOI: 10.1002/hep.23000

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      Increased rate of death related to presence of viremia among hepatitis C virus antibody–positive subjects in a community-based cohort study (pages 393–399)

      Hirofumi Uto, Sherri O. Stuver, Katsuhiro Hayashi, Kotaro Kumagai, Fumisato Sasaki, Shuji Kanmura, Masatsugu Numata, Akihiro Moriuchi, Susumu Hasegawa, Makoto Oketani, Akio Ido, Kazunori Kusumoto, Satoru Hasuike, Kenji Nagata, Michinori Kohara and Hirohito Tsubouchi

      Article first published online: 1 APR 2009 | DOI: 10.1002/hep.23002

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      Sustained virological response to interferon plus ribavirin reduces liver-related complications and mortality in patients coinfected with human immunodeficiency virus and hepatitis C virus (pages 407–413)

      Juan Berenguer, Julio Álvarez-Pellicer, Pilar Miralles Martín, José López-Aldeguer, Miguel Angel Von-Wichmann, Carmen Quereda, Josep Mallolas, José Sanz, Cristina Tural, José María Bellón, Juan González-García and The GESIDA3603/5607 Study Group

      Article first published online: 2 JUL 2009 | DOI: 10.1002/hep.23020

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      Polo-like kinase 1 inhibition suppresses hepatitis B virus X protein-induced transformation in an in vitro model of liver cancer progression (pages 414–423)

      Leo L. Studach, Lova Rakotomalala, Wen-Horng Wang, Ronald L. Hullinger, Stefano Cairo, Marie-Annick Buendia and Ourania M. Andrisani

      Article first published online: 8 MAY 2009 | DOI: 10.1002/hep.22996

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  5. Steatohepatitis/Metabolic Liver Disease

    1. Top of page
    2. Master's Perspective
    3. Comments from the Editors
    4. Editorials
    5. Viral Hepatitis
    6. Steatohepatitis/Metabolic Liver Disease
    7. Hepatobiliary Malignancies
    8. Autoimmune, Cholestatic and Biliary Disease
    9. Liver Failure/Cirrhosis/Portal Hypertension
    10. Liver Injury/Regeneration
    11. Liver Biology/Pathobiology
    12. Reviews
    13. Hepatology Elsewhere
    14. Image of the Month
    15. Correspondence
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      Specific role for acyl CoA:Diacylglycerol acyltransferase 1 (Dgat1) in hepatic steatosis due to exogenous fatty acids (pages 434–442)

      Claudio J. Villanueva, Mara Monetti, Michelle Shih, Ping Zhou, Steve M. Watkins, Sanjay Bhanot and Robert V. Farese Jr.

      Article first published online: 19 MAR 2009 | DOI: 10.1002/hep.22980

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      Impaired liver regeneration in mice lacking glycine N-methyltransferase (pages 443–452)

      Marta Varela-Rey, David Fernández-Ramos, Nuria Martínez-López, Nieves Embade, Laura Gómez-Santos, Naiara Beraza, Mercedes Vázquez-Chantada, Juan Rodríguez, Zigmund Luka, Conrad Wagner, Shelly C. Lu, M. Luz Martínez-Chantar and José M. Mato

      Article first published online: 17 APR 2009 | DOI: 10.1002/hep.23033

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      Ethanol-induced cytochrome P4502E1 causes carcinogenic etheno-DNA lesions in alcoholic liver disease (pages 453–461)

      Ying Wang, Gunda Millonig, Jagadeesan Nair, Eleonora Patsenker, Felix Stickel, Sebastian Mueller, Helmut Bartsch and Helmut K. Seitz

      Article first published online: 19 MAR 2009 | DOI: 10.1002/hep.22978

  6. Hepatobiliary Malignancies

    1. Top of page
    2. Master's Perspective
    3. Comments from the Editors
    4. Editorials
    5. Viral Hepatitis
    6. Steatohepatitis/Metabolic Liver Disease
    7. Hepatobiliary Malignancies
    8. Autoimmune, Cholestatic and Biliary Disease
    9. Liver Failure/Cirrhosis/Portal Hypertension
    10. Liver Injury/Regeneration
    11. Liver Biology/Pathobiology
    12. Reviews
    13. Hepatology Elsewhere
    14. Image of the Month
    15. Correspondence
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      S-adenosylmethionine in the chemoprevention and treatment of hepatocellular carcinoma in a rat model (pages 462–471)

      Shelly C. Lu, Komal Ramani, Xiaopeng Ou, Mark Lin, Victor Yu, Kwangsuk Ko, Ryan Park, Teodoro Bottiglieri, Hidekazu Tsukamoto, Gary Kanel, Samuel W. French, José M. Mato, Rex Moats and Edward Grant

      Article first published online: 6 APR 2009 | DOI: 10.1002/hep.22990

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      Identification of microRNA-181 by genome-wide screening as a critical player in EpCAM–positive hepatic cancer stem cells (pages 472–480)

      Junfang Ji, Taro Yamashita, Anuradha Budhu, Marshonna Forgues, Hu-Liang Jia, Cuiling Li, Chuxia Deng, Elaine Wauthier, Lola M. Reid, Qing-Hai Ye, Lun-Xiu Qin, Wen Yang, Hong-Yang Wang, Zhao-You Tang, Carlo M. Croce and Xin Wei Wang

      Article first published online: 3 APR 2009 | DOI: 10.1002/hep.22989

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      Hepatocellular adenoma management and phenotypic classification: The Bordeaux experience (pages 481–489)

      Paulette Bioulac-Sage, Hervé Laumonier, Gabrielle Couchy, Brigitte Le Bail, Antonio Sa Cunha, Anne Rullier, Christophe Laurent, Jean-Frédéric Blanc, Gaelle Cubel, Hervé Trillaud, Jessica Zucman-Rossi, Charles Balabaud and Jean Saric

      Article first published online: 11 MAY 2009 | DOI: 10.1002/hep.22995

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      Rapamycin delays tumor development in murine livers by inhibiting proliferation of hepatocytes with DNA damage (pages 500–509)

      Laura Elisa Buitrago-Molina, Deepika Pothiraju, Jutta Lamlé, Silke Marhenke, Uta Kossatz, Kai Breuhahn, Michael P. Manns, Nisar Malek and Arndt Vogel

      Article first published online: 7 APR 2009 | DOI: 10.1002/hep.23014

  7. Autoimmune, Cholestatic and Biliary Disease

    1. Top of page
    2. Master's Perspective
    3. Comments from the Editors
    4. Editorials
    5. Viral Hepatitis
    6. Steatohepatitis/Metabolic Liver Disease
    7. Hepatobiliary Malignancies
    8. Autoimmune, Cholestatic and Biliary Disease
    9. Liver Failure/Cirrhosis/Portal Hypertension
    10. Liver Injury/Regeneration
    11. Liver Biology/Pathobiology
    12. Reviews
    13. Hepatology Elsewhere
    14. Image of the Month
    15. Correspondence
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    2. You have free access to this content
      Repair-related activation of hedgehog signaling promotes cholangiocyte chemokine production (pages 518–527)

      Alessia Omenetti, Wing-Kin Syn, Youngmi Jung, Heather Francis, Alessandro Porrello, Rafal P. Witek, Steve S. Choi, Liu Yang, Marlyn J. Mayo, M. Eric Gershwin, Gianfranco Alpini and Anna Mae Diehl

      Article first published online: 2 JUL 2009 | DOI: 10.1002/hep.23019

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      Prevalence of sclerosing cholangitis in adults with autoimmune hepatitis: A prospective magnetic resonance imaging and histological study (pages 528–537)

      Maïté Lewin, Valérie Vilgrain, Violaine Ozenne, Maud Lemoine, Dominique Wendum, Valérie Paradis, Marianne Ziol, Lionel Arrivé, Michel Beaugrand, Raoul Poupon, Dominique Valla, Olivier Chazouillères and Christophe Corpechot

      Article first published online: 17 APR 2009 | DOI: 10.1002/hep.23024

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      Diagnostic value and utility of the simplified International Autoimmune Hepatitis Group (IAIHG) criteria in acute and chronic liver disease (pages 538–545)

      Andrew D. Yeoman, Rachel H. Westbrook, Thawab Al-Chalabi, Ivana Carey, Nigel D. Heaton, Bernard C. Portmann and Michael A. Heneghan

      Article first published online: 22 APR 2009 | DOI: 10.1002/hep.23042

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      Keratin variants are overrepresented in primary biliary cirrhosis and associate with disease severity (pages 546–554)

      Bihui Zhong, Pavel Strnad, Carlo Selmi, Pietro Invernizzi, Guo-Zhong Tao, Angela Caleffi, Minhu Chen, Ilaria Bianchi, Mauro Podda, Antonello Pietrangelo, M. Eric Gershwin and M. Bishr Omary

      Article first published online: 22 APR 2009 | DOI: 10.1002/hep.23041

  8. Liver Failure/Cirrhosis/Portal Hypertension

    1. Top of page
    2. Master's Perspective
    3. Comments from the Editors
    4. Editorials
    5. Viral Hepatitis
    6. Steatohepatitis/Metabolic Liver Disease
    7. Hepatobiliary Malignancies
    8. Autoimmune, Cholestatic and Biliary Disease
    9. Liver Failure/Cirrhosis/Portal Hypertension
    10. Liver Injury/Regeneration
    11. Liver Biology/Pathobiology
    12. Reviews
    13. Hepatology Elsewhere
    14. Image of the Month
    15. Correspondence
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      Alterations in the functional capacity of albumin in patients with decompensated cirrhosis is associated with increased mortality (pages 555–564)

      Rajiv Jalan, Kerstin Schnurr, Rajeshwar P. Mookerjee, Sambit Sen, Lisa Cheshire, Stephen Hodges, Vladimir Muravsky, Roger Williams, Gert Matthes and Nathan A. Davies

      Article first published online: 18 FEB 2009 | DOI: 10.1002/hep.22913

  9. Liver Injury/Regeneration

    1. Top of page
    2. Master's Perspective
    3. Comments from the Editors
    4. Editorials
    5. Viral Hepatitis
    6. Steatohepatitis/Metabolic Liver Disease
    7. Hepatobiliary Malignancies
    8. Autoimmune, Cholestatic and Biliary Disease
    9. Liver Failure/Cirrhosis/Portal Hypertension
    10. Liver Injury/Regeneration
    11. Liver Biology/Pathobiology
    12. Reviews
    13. Hepatology Elsewhere
    14. Image of the Month
    15. Correspondence
    1. You have free access to this content
      Cisplatin prevents high mobility group box 1 release and is protective in a murine model of hepatic ischemia/reperfusion injury (pages 565–574)

      Jon Cardinal, Pinhua Pan, Rajeev Dhupar, Mark Ross, Atsunori Nakao, Michael Lotze, Timothy Billiar, David Geller and Allan Tsung

      Article first published online: 2 JUN 2009 | DOI: 10.1002/hep.23021

  10. Liver Biology/Pathobiology

    1. Top of page
    2. Master's Perspective
    3. Comments from the Editors
    4. Editorials
    5. Viral Hepatitis
    6. Steatohepatitis/Metabolic Liver Disease
    7. Hepatobiliary Malignancies
    8. Autoimmune, Cholestatic and Biliary Disease
    9. Liver Failure/Cirrhosis/Portal Hypertension
    10. Liver Injury/Regeneration
    11. Liver Biology/Pathobiology
    12. Reviews
    13. Hepatology Elsewhere
    14. Image of the Month
    15. Correspondence
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      Interleukin-27 displays interferon-γ–like functions in human hepatoma cells and hepatocytes (pages 585–591)

      Herdis Bender, Monique Y. Wiesinger, Carolin Nordhoff, Caroline Schoenherr, Claude Haan, Stephan Ludwig, Ralf Weiskirchen, Nobuyuki Kato, Peter C. Heinrich and Serge Haan

      Article first published online: 6 APR 2009 | DOI: 10.1002/hep.22988

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      Lipopolysaccharide inhibition of glucose production through the Toll-like receptor-4, myeloid differentiation factor 88, and nuclear factor κb pathway (pages 592–600)

      Carl F. Raetzsch, Natasha L. Brooks, J. McKee Alderman, Kelli S. Moore, Peter A. Hosick, Simon Klebanov, Shizuo Akira, James E. Bear, Albert S. Baldwin, Nigel Mackman and Terry P. Combs

      Article first published online: 2 JUN 2009 | DOI: 10.1002/hep.22999

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      Thymus cell antigen-1-expressing cells in the oval cell compartment (pages 601–611)

      Mladen I. Yovchev, Jialin Zhang, David S. Neufeld, Petar N. Grozdanov and Mariana D. Dabeva

      Article first published online: 6 APR 2009 | DOI: 10.1002/hep.23012

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  11. Reviews

    1. Top of page
    2. Master's Perspective
    3. Comments from the Editors
    4. Editorials
    5. Viral Hepatitis
    6. Steatohepatitis/Metabolic Liver Disease
    7. Hepatobiliary Malignancies
    8. Autoimmune, Cholestatic and Biliary Disease
    9. Liver Failure/Cirrhosis/Portal Hypertension
    10. Liver Injury/Regeneration
    11. Liver Biology/Pathobiology
    12. Reviews
    13. Hepatology Elsewhere
    14. Image of the Month
    15. Correspondence
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  12. Hepatology Elsewhere

    1. Top of page
    2. Master's Perspective
    3. Comments from the Editors
    4. Editorials
    5. Viral Hepatitis
    6. Steatohepatitis/Metabolic Liver Disease
    7. Hepatobiliary Malignancies
    8. Autoimmune, Cholestatic and Biliary Disease
    9. Liver Failure/Cirrhosis/Portal Hypertension
    10. Liver Injury/Regeneration
    11. Liver Biology/Pathobiology
    12. Reviews
    13. Hepatology Elsewhere
    14. Image of the Month
    15. Correspondence
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      Dropping liver fat droplets (pages 645–647)

      Sander Kersten and Michael Müller

      Article first published online: 29 JUL 2009 | DOI: 10.1002/hep.23142

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  13. Image of the Month

    1. Top of page
    2. Master's Perspective
    3. Comments from the Editors
    4. Editorials
    5. Viral Hepatitis
    6. Steatohepatitis/Metabolic Liver Disease
    7. Hepatobiliary Malignancies
    8. Autoimmune, Cholestatic and Biliary Disease
    9. Liver Failure/Cirrhosis/Portal Hypertension
    10. Liver Injury/Regeneration
    11. Liver Biology/Pathobiology
    12. Reviews
    13. Hepatology Elsewhere
    14. Image of the Month
    15. Correspondence
    1. You have free access to this content
  14. Correspondence

    1. Top of page
    2. Master's Perspective
    3. Comments from the Editors
    4. Editorials
    5. Viral Hepatitis
    6. Steatohepatitis/Metabolic Liver Disease
    7. Hepatobiliary Malignancies
    8. Autoimmune, Cholestatic and Biliary Disease
    9. Liver Failure/Cirrhosis/Portal Hypertension
    10. Liver Injury/Regeneration
    11. Liver Biology/Pathobiology
    12. Reviews
    13. Hepatology Elsewhere
    14. Image of the Month
    15. Correspondence
    1. You have free access to this content
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      Reply: (page 653)

      Laura Kulik and Riad Salem

      Article first published online: 11 MAY 2009 | DOI: 10.1002/hep.23066

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      Hepatic failure due to hepatitis B reactivation in a patient with ulcerative colitis treated with prednisone (pages 653–654)

      Jonas Zeitz, Beat Mullhaupt, Heiko Fruehauf, Gerhard Rogler and Stephan R. Vavricka

      Article first published online: 22 APR 2009 | DOI: 10.1002/hep.23035

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      Reply: (pages 655–656)

      Don C. Rockey, Stephen H. Caldwell, Zachary D. Goodman, Rendon C. Nelson and Alastair D. Smith

      Article first published online: 20 MAY 2009 | DOI: 10.1002/hep.23086

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      Reply: (page 657)

      Giada Sebastiani and Alfredo Alberti

      Article first published online: 26 MAY 2009 | DOI: 10.1002/hep.23091

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      Reply: (pages 658–659)

      Anna S. Lok

      Article first published online: 8 JUN 2009 | DOI: 10.1002/hep.23115

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