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Hepatology

Cover image for Vol. 55 Issue 5

May 2012

Volume 55, Issue 5

Pages 1313–1645

  1. Editorials

    1. Top of page
    2. Editorials
    3. Viral Hepatitis
    4. Steatohepatitis/Metabolic Liver Disease
    5. Hepatobiliary Malignancies
    6. Autoimmune, Cholestatic and Biliary Disease
    7. Liver Failure/Cirrhosis/Portal Hypertension
    8. Liver Injury/Regeneration
    9. Liver Biology/Pathobiology
    10. Reviews
    11. Hepatology Elsewhere
    12. Perspectives in Clinical Hepatology
    13. Correspondence
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  2. Viral Hepatitis

    1. Top of page
    2. Editorials
    3. Viral Hepatitis
    4. Steatohepatitis/Metabolic Liver Disease
    5. Hepatobiliary Malignancies
    6. Autoimmune, Cholestatic and Biliary Disease
    7. Liver Failure/Cirrhosis/Portal Hypertension
    8. Liver Injury/Regeneration
    9. Liver Biology/Pathobiology
    10. Reviews
    11. Hepatology Elsewhere
    12. Perspectives in Clinical Hepatology
    13. Correspondence
    1. You have free access to this content
      Carotid atherosclerosis and chronic hepatitis C: A prospective study of risk associations (pages 1317–1323)

      Salvatore Petta, Daniele Torres, Giovanni Fazio, Calogero Cammà, Daniela Cabibi, Vito Di Marco, Anna Licata, Giulio Marchesini, Alessandra Mazzola, Gaspare Parrinello, Salvatore Novo, Giuseppe Licata and Antonio Craxì

      Article first published online: 4 APR 2012 | DOI: 10.1002/hep.25508

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      Suppression of interferon-α signaling by hepatitis E virus (pages 1324–1332)

      Chen Dong, Mohammad Zafrullah, Tonya Mixson-Hayden, Xing Dai, Jiuhong Liang, Jihong Meng and Saleem Kamili

      Article first published online: 4 APR 2012 | DOI: 10.1002/hep.25530

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      The cyclophilin inhibitor alisporivir prevents hepatitis C virus–mediated mitochondrial dysfunction (pages 1333–1343)

      Giovanni Quarato, Annamaria D'Aprile, Bruno Gavillet, Grégoire Vuagniaux, Darius Moradpour, Nazzareno Capitanio and Claudia Piccoli

      Article first published online: 18 MAR 2012 | DOI: 10.1002/hep.25514

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      Economic model of a birth cohort screening program for hepatitis C virus (pages 1344–1355)

      Lisa J. McGarry, Vivek S. Pawar, Hemangi R. Panchmatia, Jaime L. Rubin, Gary L. Davis, Zobair M. Younossi, James C. Capretta, Michael J. O'Grady and Milton C. Weinstein

      Article first published online: 18 MAR 2012 | DOI: 10.1002/hep.25510

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      Phospholipid transfer activity of microsomal triglyceride transfer protein produces apolipoprotein B and reduces hepatosteatosis while maintaining low plasma lipids in mice (pages 1356–1368)

      Irani Khatun, Sebastian Zeissig, Jahangir Iqbal, Minghui Wang, David Curiel, Gregory S. Shelness, Richard S. Blumberg and M.Mahmood Hussain

      Article first published online: 20 MAR 2012 | DOI: 10.1002/hep.25504

  3. Steatohepatitis/Metabolic Liver Disease

    1. Top of page
    2. Editorials
    3. Viral Hepatitis
    4. Steatohepatitis/Metabolic Liver Disease
    5. Hepatobiliary Malignancies
    6. Autoimmune, Cholestatic and Biliary Disease
    7. Liver Failure/Cirrhosis/Portal Hypertension
    8. Liver Injury/Regeneration
    9. Liver Biology/Pathobiology
    10. Reviews
    11. Hepatology Elsewhere
    12. Perspectives in Clinical Hepatology
    13. Correspondence
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    2. You have free access to this content
      Retinoic acid receptor–related orphan receptor α–induced activation of adenosine monophosphate–activated protein kinase results in attenuation of hepatic steatosis (pages 1379–1388)

      Eun-Jin Kim, Young-Sil Yoon, Suckchang Hong, Ho-Young Son, Tae-Young Na, Min-Ho Lee, Hyun-Jin Kang, Jinyoung Park, Won-Jea Cho, Sang-Gun Kim, Seung-Hoi Koo, Hyeung-geun Park and Mi-Ock Lee

      Article first published online: 19 APR 2012 | DOI: 10.1002/hep.25529

      Corrected by:

      Correction: Correction

      Vol. 57, Issue 1, 423, Article first published online: 7 JAN 2013

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      Effect of adipose tissue insulin resistance on metabolic parameters and liver histology in obese patients with nonalcoholic fatty liver disease (pages 1389–1397)

      Romina Lomonaco, Carolina Ortiz-Lopez, Beverly Orsak, Amy Webb, Jean Hardies, Celia Darland, Joan Finch, Amalia Gastaldelli, Stephen Harrison, Fermin Tio and Kenneth Cusi

      Article first published online: 18 MAR 2012 | DOI: 10.1002/hep.25539

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      Outcomes after liver transplantation for alcoholic hepatitis are similar to alcoholic cirrhosis: Exploratory analysis from the UNOS database (pages 1398–1405)

      Ashwani K. Singal, Hmoud Bashar, Bhupinderjit S. Anand, Sarat C. Jampana, Vineet Singal and Yong-Fang Kuo

      Article first published online: 18 MAR 2012 | DOI: 10.1002/hep.25544

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      Fatty liver index, gamma-glutamyltransferase, and early carotid plaques (pages 1406–1415)

      Michaela Kozakova, Carlo Palombo, Marco Paterni Eng, Jacqueline Dekker, Allan Flyvbjerg, Asimina Mitrakou, Amalia Gastaldelli, Ele Ferrannini and ; and the RISC Investigators

      Article first published online: 19 APR 2012 | DOI: 10.1002/hep.25555

  4. Hepatobiliary Malignancies

    1. Top of page
    2. Editorials
    3. Viral Hepatitis
    4. Steatohepatitis/Metabolic Liver Disease
    5. Hepatobiliary Malignancies
    6. Autoimmune, Cholestatic and Biliary Disease
    7. Liver Failure/Cirrhosis/Portal Hypertension
    8. Liver Injury/Regeneration
    9. Liver Biology/Pathobiology
    10. Reviews
    11. Hepatology Elsewhere
    12. Perspectives in Clinical Hepatology
    13. Correspondence
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      Family history of liver cancer and hepatocellular carcinoma (pages 1416–1425)

      Federica Turati, Valeria Edefonti, Renato Talamini, Monica Ferraroni, Matteo Malvezzi, Francesca Bravi, Silvia Franceschi, Maurizio Montella, Jerry Polesel, Antonella Zucchetto, Carlo La Vecchia, Eva Negri and Adriano Decarli

      Article first published online: 21 MAR 2012 | DOI: 10.1002/hep.24794

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      Genetic variants in human leukocyte antigen/DP-DQ influence both hepatitis B virus clearance and hepatocellular carcinoma development (pages 1426–1431)

      Lingmin Hu, Xiangjun Zhai, Jibin Liu, Minjie Chu, Shandong Pan, Jie Jiang, Yixin Zhang, Hua Wang, Jianguo Chen, Hongbing Shen and Zhibin Hu

      Article first published online: 16 MAR 2012 | DOI: 10.1002/hep.24799

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      Extrahepatic metastases occur in a minority of hepatocellular carcinoma patients treated with locoregional therapies: Analyzing patterns of progression in 285 patients (pages 1432–1442)

      Seanthan Senthilnathan, Khairuddin Memon, Robert J. Lewandowski, Laura Kulik, Mary F. Mulcahy, Ahsun Riaz, Frank H. Miller, Vahid Yaghmai, Paul Nikolaidis, Edward Wang, Talia Baker, Michael Abecassis, Al B. Benson 3rd, Reed A. Omary and Riad Salem

      Article first published online: 4 APR 2012 | DOI: 10.1002/hep.24812

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      Sixty-five gene-based risk score classifier predicts overall survival in hepatocellular carcinoma (pages 1443–1452)

      Soo Mi Kim, Sun-Hee Leem, In-Sun Chu, Yun-Yong Park, Sang Cheol Kim, Sang-Bae Kim, Eun Sung Park, Jae Yun Lim, Jeonghoon Heo, Yoon Jun Kim, Dae-Ghon Kim, Ahmed Kaseb, Young Nyun Park, Xin Wei Wang, Snorri S. Thorgeirsson and Ju-Seog Lee

      Article first published online: 18 MAR 2012 | DOI: 10.1002/hep.24813

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      Sequential alterations of microrna expression in hepatocellular carcinoma development and venous metastasis (pages 1453–1461)

      Chun-Ming Wong, Carmen Chak-Lui Wong, Joyce Man-Fong Lee, Dorothy Ngo-Yin Fan, Sandy Leung-Kuen Au and Irene Oi-Lin Ng

      Article first published online: 19 APR 2012 | DOI: 10.1002/hep.25512

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      Association of thiazolidinediones with liver cancer and colorectal cancer in type 2 diabetes mellitus (pages 1462–1472)

      Chia-Hsuin Chang, Jou-Wei Lin, Li-Chiu Wu, Mei-Shu Lai, Lee-Ming Chuang and K. Arnold Chan

      Article first published online: 19 APR 2012 | DOI: 10.1002/hep.25509

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      V-AKT murine thymoma viral oncogene homolog/mammalian target of rapamycin activation induces a module of metabolic changes contributing to growth in insulin-induced hepatocarcinogenesis (pages 1473–1484)

      Matthias Evert, Diego F. Calvisi, Katja Evert, Valentina De Murtas, Gioia Gasparetti, Sandra Mattu, Giulia Destefanis, Sara Ladu, Antje Zimmermann, Salvatore Delogu, Sara Thiel, Andrea Thiele, Silvia Ribback and Frank Dombrowski

      Article first published online: 4 APR 2012 | DOI: 10.1002/hep.25600

  5. Autoimmune, Cholestatic and Biliary Disease

    1. Top of page
    2. Editorials
    3. Viral Hepatitis
    4. Steatohepatitis/Metabolic Liver Disease
    5. Hepatobiliary Malignancies
    6. Autoimmune, Cholestatic and Biliary Disease
    7. Liver Failure/Cirrhosis/Portal Hypertension
    8. Liver Injury/Regeneration
    9. Liver Biology/Pathobiology
    10. Reviews
    11. Hepatology Elsewhere
    12. Perspectives in Clinical Hepatology
    13. Correspondence
    1. You have free access to this content
      Elevated hepatic multidrug resistance-associated protein 3/ATP-binding cassette subfamily C 3 expression in human obstructive cholestasis is mediated through tumor necrosis factor alpha and c-Jun NH2-terminal kinase/stress-activated protein kinase–signaling pathway (pages 1485–1494)

      Jin Chai, Yu He, Shi-Ying Cai, Zhongyong Jiang, Huaizhi Wang, Qiong Li, Lei Chen, Zhihong Peng, Xiaochong He, Xiaoping Wu, Tianli Xiao, Rongquan Wang, James L. Boyer and Wensheng Chen

      Article first published online: 19 APR 2012 | DOI: 10.1002/hep.24801

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      Comparative analysis of portal cell infiltrates in antimitochondrial autoantibody–positive versus antimitochondrial autoantibody–negative primary biliary cirrhosis (pages 1495–1506)

      Qinglong Jin, Yuki Moritoki, Ana Lleo, Koichi Tsuneyama, Pietro Invernizzi, Hitoshi Moritoki, Kentaro Kikuchi, Zhe-Xiong Lian, Gideon M. Hirschfield, Aftab A. Ansari, Ross L. Coppel, M. Eric Gershwin and Junqi Niu

      Article first published online: 4 APR 2012 | DOI: 10.1002/hep.25511

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      Phytosterol and cholesterol precursor levels indicate increased cholesterol excretion and biosynthesis in gallstone disease (pages 1507–1517)

      Marcin Krawczyk, Dieter Lütjohann, Ramin Schirin-Sokhan, Luis Villarroel, Flavio Nervi, Fernando Pimentel, Frank Lammert and Juan Francisco Miquel

      Article first published online: 4 APR 2012 | DOI: 10.1002/hep.25563

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      Toll-like receptor 4–dependent Kupffer cell activation and liver injury in a novel mouse model of parenteral nutrition and intestinal injury (pages 1518–1528)

      Karim C. El Kasmi, Aimee L. Anderson, Michael W. Devereaux, Sophie A. Fillon, J. Kirk Harris, Mark A. Lovell, Milton J. Finegold and Ronald J. Sokol

      Article first published online: 18 MAR 2012 | DOI: 10.1002/hep.25500

  6. Liver Failure/Cirrhosis/Portal Hypertension

    1. Top of page
    2. Editorials
    3. Viral Hepatitis
    4. Steatohepatitis/Metabolic Liver Disease
    5. Hepatobiliary Malignancies
    6. Autoimmune, Cholestatic and Biliary Disease
    7. Liver Failure/Cirrhosis/Portal Hypertension
    8. Liver Injury/Regeneration
    9. Liver Biology/Pathobiology
    10. Reviews
    11. Hepatology Elsewhere
    12. Perspectives in Clinical Hepatology
    13. Correspondence
    1. You have free access to this content
      The microenvironment in hepatocyte regeneration and function in rats with advanced cirrhosis (pages 1529–1539)

      Liping Liu, Govardhana Rao Yannam, Taichiro Nishikawa, Toshiyuki Yamamoto, Hesham Basma, Ryotaro Ito, Masaki Nagaya, Joyeeta Dutta-Moscato, Donna B. Stolz, Fenghai Duan, Klaus H. Kaestner, Yoram Vodovotz, Alejandro Soto-Gutierrez and Ira J. Fox

      Article first published online: 4 APR 2012 | DOI: 10.1002/hep.24815

      Corrected by:

      Correction: Corrections

      Vol. 56, Issue 1, 397, Article first published online: 3 JUL 2012

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      Hepatic endothelin-1 and endocannabinoids-dependent effects of hyperleptinemia in nonalcoholic steatohepatitis-cirrhotic rats (pages 1540–1550)

      Ying-Ying Yang, Tung-Hu Tsai, Yi-Tsau Huang, Tzung-Yan Lee, Che-Chang Chan, Kuei-Chuan Lee and Han-Chieh Lin

      Article first published online: 4 APR 2012 | DOI: 10.1002/hep.25534

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      Prevalence and risk factors of infections by multiresistant bacteria in cirrhosis: A prospective study (pages 1551–1561)

      Javier Fernández, Juan Acevedo, Miriam Castro, Orlando Garcia, Carlos Rodríguez de Lope, Daria Roca, Marco Pavesi, Elsa Sola, Leticia Moreira, Anibal Silva, Tiago Seva-Pereira, Francesco Corradi, Jose Mensa, Pere Ginès and Vicente Arroyo

      Article first published online: 4 APR 2012 | DOI: 10.1002/hep.25532

  7. Liver Injury/Regeneration

    1. Top of page
    2. Editorials
    3. Viral Hepatitis
    4. Steatohepatitis/Metabolic Liver Disease
    5. Hepatobiliary Malignancies
    6. Autoimmune, Cholestatic and Biliary Disease
    7. Liver Failure/Cirrhosis/Portal Hypertension
    8. Liver Injury/Regeneration
    9. Liver Biology/Pathobiology
    10. Reviews
    11. Hepatology Elsewhere
    12. Perspectives in Clinical Hepatology
    13. Correspondence
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    2. You have free access to this content
      Caveolin-1 orchestrates the balance between glucose and lipid-dependent energy metabolism: Implications for liver regeneration (pages 1574–1584)

      Manuel Alejandro Fernández-Rojo, Christina Restall, Charles Ferguson, Nick Martel, Sally Martin, Marta Bosch, Adam Kassan, Gary M. Leong, Sheree D. Martin, Sean L. McGee, George E.O. Muscat, Robin L. Anderson, Carlos Enrich, Albert Pol and Robert G. Parton

      Article first published online: 4 APR 2012 | DOI: 10.1002/hep.24810

  8. Liver Biology/Pathobiology

    1. Top of page
    2. Editorials
    3. Viral Hepatitis
    4. Steatohepatitis/Metabolic Liver Disease
    5. Hepatobiliary Malignancies
    6. Autoimmune, Cholestatic and Biliary Disease
    7. Liver Failure/Cirrhosis/Portal Hypertension
    8. Liver Injury/Regeneration
    9. Liver Biology/Pathobiology
    10. Reviews
    11. Hepatology Elsewhere
    12. Perspectives in Clinical Hepatology
    13. Correspondence
    1. You have free access to this content
    2. You have free access to this content
      Argininosuccinate synthase conditions the response to acute and chronic ethanol-induced liver injury in mice (pages 1596–1609)

      Tung Ming Leung, Yongke Lu, Wei Yan, José A. Morón-Concepción, Stephen C. Ward, Xiaodong Ge, Laura Conde de la Rosa and Natalia Nieto

      Article first published online: 19 APR 2012 | DOI: 10.1002/hep.25543

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      Chemokine Cxcl9 attenuates liver fibrosis-associated angiogenesis in mice (pages 1610–1619)

      Hacer Sahin, Erawan Borkham-Kamphorst, Christoph Kuppe, Mirko Moreno Zaldivar, Christoph Grouls, Muhammad Al-samman, Andreas Nellen, Petra Schmitz, Daniel Heinrichs, Marie-Luise Berres, Dennis Doleschel, David Scholten, Ralf Weiskirchen, Marcus J. Moeller, Fabian Kiessling, Christian Trautwein and Hermann E. Wasmuth

      Article first published online: 19 APR 2012 | DOI: 10.1002/hep.25545

  9. Reviews

    1. Top of page
    2. Editorials
    3. Viral Hepatitis
    4. Steatohepatitis/Metabolic Liver Disease
    5. Hepatobiliary Malignancies
    6. Autoimmune, Cholestatic and Biliary Disease
    7. Liver Failure/Cirrhosis/Portal Hypertension
    8. Liver Injury/Regeneration
    9. Liver Biology/Pathobiology
    10. Reviews
    11. Hepatology Elsewhere
    12. Perspectives in Clinical Hepatology
    13. Correspondence
    1. You have free access to this content
      Review and management of drug interactions with boceprevir and telaprevir (pages 1620–1628)

      Jennifer J. Kiser, James R. Burton, Peter L. Anderson and Gregory T. Everson

      Article first published online: 19 APR 2012 | DOI: 10.1002/hep.25653

  10. Hepatology Elsewhere

    1. Top of page
    2. Editorials
    3. Viral Hepatitis
    4. Steatohepatitis/Metabolic Liver Disease
    5. Hepatobiliary Malignancies
    6. Autoimmune, Cholestatic and Biliary Disease
    7. Liver Failure/Cirrhosis/Portal Hypertension
    8. Liver Injury/Regeneration
    9. Liver Biology/Pathobiology
    10. Reviews
    11. Hepatology Elsewhere
    12. Perspectives in Clinical Hepatology
    13. Correspondence
    1. You have free access to this content
    2. You have free access to this content
    3. You have free access to this content
  11. Perspectives in Clinical Hepatology

    1. Top of page
    2. Editorials
    3. Viral Hepatitis
    4. Steatohepatitis/Metabolic Liver Disease
    5. Hepatobiliary Malignancies
    6. Autoimmune, Cholestatic and Biliary Disease
    7. Liver Failure/Cirrhosis/Portal Hypertension
    8. Liver Injury/Regeneration
    9. Liver Biology/Pathobiology
    10. Reviews
    11. Hepatology Elsewhere
    12. Perspectives in Clinical Hepatology
    13. Correspondence
    1. You have free access to this content
  12. Correspondence

    1. Top of page
    2. Editorials
    3. Viral Hepatitis
    4. Steatohepatitis/Metabolic Liver Disease
    5. Hepatobiliary Malignancies
    6. Autoimmune, Cholestatic and Biliary Disease
    7. Liver Failure/Cirrhosis/Portal Hypertension
    8. Liver Injury/Regeneration
    9. Liver Biology/Pathobiology
    10. Reviews
    11. Hepatology Elsewhere
    12. Perspectives in Clinical Hepatology
    13. Correspondence
    1. You have free access to this content
      Ethnic differences in viral dominance patterns in patients with hepatitis B virus and hepatitis C virus dual infection (page 1640)

      Gabriele Rockenbach, Alexandre JosÉ De Melo Neto, Nêmora Tregnago Barcellos and Fernando Herz Wolff

      Article first published online: 19 APR 2012 | DOI: 10.1002/hep.24533

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      Reply (page 1640)

      Long H. Nguyen and Mindie Nguyen

      Article first published online: 19 APR 2012 | DOI: 10.1002/hep.25719

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      Reply (pages 1642–1643)

      Philip Starkey Lewis, James Dear, Vivien Platt, Jonathan Moggs, Chris Goldring and B. Kevin Park

      Article first published online: 19 APR 2012 | DOI: 10.1002/hep.25565

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      Hepatitis E virus-specific T-cell response after transplantation (page 1643)

      Nassim Kamar, Florence Legrand-Abravanel, Harry R. Dalton and Jacques Izopet

      Article first published online: 19 APR 2012 | DOI: 10.1002/hep.25578

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      Reply (page 1644)

      Pothakamuri Venkata Suneetha, Sven Pischke and Heiner Wedemeyer

      Article first published online: 19 APR 2012 | DOI: 10.1002/hep.25577

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