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Hepatology

Cover image for Vol. 56 Issue 5

November 2012

Volume 56, Issue 5

Pages 1591–2011

  1. Editorials

    1. Top of page
    2. Editorials
    3. Viral Hepatitis
    4. Steatohepatitis/Metabolic Liver Disease
    5. Hepatobiliary Malignancies
    6. Autoimmune, Cholestatic and Biliary Disease
    7. Liver Failure/Cirrhosis/Portal Hypertension
    8. Liver Injury/Regeneration
    9. Liver Biology/Pathobiology
    10. Reviews
    11. Hepatology Elsewhere
    12. Clinical Observations in Hepatology
    13. Correspondence
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  2. Viral Hepatitis

    1. Top of page
    2. Editorials
    3. Viral Hepatitis
    4. Steatohepatitis/Metabolic Liver Disease
    5. Hepatobiliary Malignancies
    6. Autoimmune, Cholestatic and Biliary Disease
    7. Liver Failure/Cirrhosis/Portal Hypertension
    8. Liver Injury/Regeneration
    9. Liver Biology/Pathobiology
    10. Reviews
    11. Hepatology Elsewhere
    12. Clinical Observations in Hepatology
    13. Correspondence
    1. You have free access to this content
      B cell homeostasis in chronic hepatitis C virus–related mixed cryoglobulinemia is maintained through naïve B cell apoptosis (pages 1602–1610)

      Lauren E. Holz, Joo Chun Yoon, Sukanya Raghuraman, Susan Moir, Michael C. Sneller and Barbara Rehermann

      Article first published online: 14 OCT 2012 | DOI: 10.1002/hep.25821

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      Comprehensive analysis for viral elements and interleukin-28B polymorphisms in response to pegylated interferon plus ribavirin therapy in hepatitis C virus 1B infection (pages 1611–1621)

      Shinya Maekawa, Minoru Sakamoto, Mika Miura, Makoto Kadokura, Ryota Sueki, Kazuki Komase, Hiroko Shindo, Nobutoshi Komatsu, Kuniaki Shindo, Asuka Kanayama, Takako Ohmori, Fumitake Amemiya, Shinichi Takano, Tatsuya Yamaguchi, Yasuhiro Nakayama, Takatoshi Kitamura, Taisuke Inoue, Shunichi Okada and Nobuyuki Enomoto

      Article first published online: 31 OCT 2012 | DOI: 10.1002/hep.25826

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      Pharmacokinetic interaction between the hepatitis C virus protease inhibitor boceprevir and cyclosporine and tacrolimus in healthy volunteers (pages 1622–1630)

      Ellen Hulskotte, Samir Gupta, Fengjuan Xuan, Marga van Zutven, Edward O'Mara, Hwa-Ping Feng, John Wagner and Joan Butterton

      Article first published online: 14 OCT 2012 | DOI: 10.1002/hep.25831

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      Vitamin D binding protein gene polymorphisms and baseline vitamin D levels as predictors of antiviral response in chronic hepatitis C (pages 1641–1650)

      Edmondo Falleti, Davide Bitetto, Carlo Fabris, Giovanna Fattovich, Annarosa Cussigh, Sara Cmet, Elisa Ceriani, Ezio Fornasiere, Michela Pasino, Donatella Ieluzzi, Mario Pirisi and Pierluigi Toniutto

      Article first published online: 14 OCT 2012 | DOI: 10.1002/hep.25848

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      Impact of disease severity on healthcare costs in patients with chronic hepatitis C (CHC) virus infection (pages 1651–1660)

      Stuart C. Gordon, Paul J. Pockros, Norah A. Terrault, Robert S. Hoop, Ami Buikema, David Nerenz and Fayez M. Hamzeh

      Article first published online: 9 OCT 2012 | DOI: 10.1002/hep.25842

      Corrected by:

      Correction: Impact of disease severity on healthcare costs in patients with chronic hepatitis C (CHC) virus infection

      Vol. 58, Issue 3, 1193, Article first published online: 1 AUG 2013

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      Rare inborn errors associated with chronic hepatitis B virus infection (pages 1661–1670)

      Qiang Zhao, Liang Peng, Weijun Huang, Qibin Li, Yuanyuan Pei, Ping Yuan, Lingyan Zheng, Yongling Zhang, Jia Deng, Cheng Zhong, Bin Hu, Hongke Ding, Wei Fang, Ru Li, Qijun Liao, Chaoshuang Lin, Weiping Deng, Huijun Yan, Jinghui Hou, Qiuliang Wu, Tingting Xu, Jinsong Liu, Longbo Hu, Tao Peng, Suqing Chen, Kar N. Lai, Man-Fung Yuen, Yue Wang, Mala K. Maini, Caixia Li, Miaoxin Li, Jian Wang, Xiuqing Zhang, Pak-Chung Sham, Jun Wang, Zhi-Liang Gao and Yiming Wang

      Article first published online: 14 OCT 2012 | DOI: 10.1002/hep.25850

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      Tracing hepatitis B virus to the 16th century in a Korean mummy (pages 1671–1680)

      Gila Kahila Bar-Gal, Myeung Ju Kim, Athalia Klein, Dong Hoon Shin, Chang Seok Oh, Jong Wan Kim, Tae-Hyun Kim, Seok Bae Kim, Paul R. Grant, Orit Pappo, Mark Spigelman and Daniel Shouval

      Article first published online: 14 OCT 2012 | DOI: 10.1002/hep.25852

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      Sustained virological response prevents the development of insulin resistance in patients with chronic hepatitis C (pages 1681–1687)

      Alessio Aghemo, Gian Maria Prati, Maria Grazia Rumi, Roberta Soffredini, Roberta D'Ambrosio, Emanuela Orsi, Stella De Nicola, Elisabetta Degasperi, Valeria Grancini and Massimo Colombo

      Article first published online: 14 OCT 2012 | DOI: 10.1002/hep.25867

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      Risk of hip fracture associated with hepatitis c virus infection and hepatitis C/human immunodeficiency virus coinfection (pages 1688–1698)

      Vincent Lo Re III, Jessica Volk, Craig W. Newcomb, Yu-Xiao Yang, Cristin P. Freeman, Sean Hennessy, Jay R. Kostman, Pablo Tebas, Mary B. Leonard and A. Russell Localio

      Article first published online: 14 OCT 2012 | DOI: 10.1002/hep.25866

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      Lower liver-related death in African-American women with human immunodeficiency virus/hepatitis C virus coinfection, compared to Caucasian and Hispanic women (pages 1699–1705)

      Monika Sarkar, Peter Bacchetti, Audrey L. French, Phyllis Tien, Marshall J. Glesby, Marek Nowicki, Michael Plankey, Stephen Gange, Gerald Sharp, Howard Minkoff, Marion G. Peters and for the Women's Interagency HIV Study (WIHS)

      Article first published online: 27 AUG 2012 | DOI: 10.1002/hep.25859

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      Plasmacytoid dendritic cells induce efficient stimulation of antiviral immunity in the context of chronic hepatitis B virus infection (pages 1706–1718)

      Jeremie Martinet, Vincent Leroy, Tania Dufeu-Duchesne, Sylvie Larrat, Marie-Jeanne Richard, Fabien Zoulim, Joel Plumas and Caroline Aspord

      Article first published online: 27 AUG 2012 | DOI: 10.1002/hep.25879

  3. Steatohepatitis/Metabolic Liver Disease

    1. Top of page
    2. Editorials
    3. Viral Hepatitis
    4. Steatohepatitis/Metabolic Liver Disease
    5. Hepatobiliary Malignancies
    6. Autoimmune, Cholestatic and Biliary Disease
    7. Liver Failure/Cirrhosis/Portal Hypertension
    8. Liver Injury/Regeneration
    9. Liver Biology/Pathobiology
    10. Reviews
    11. Hepatology Elsewhere
    12. Clinical Observations in Hepatology
    13. Correspondence
    1. You have free access to this content
      Prevention of hepatocellular adenoma and correction of metabolic abnormalities in murine glycogen storage disease type Ia by gene therapy (pages 1719–1729)

      Young Mok Lee, Hyun Sik Jun, Chi-Jiunn Pan, Su Ru Lin, Lane H. Wilson, Brian C. Mansfield and Janice Y. Chou

      Article first published online: 27 AUG 2012 | DOI: 10.1002/hep.25717

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      Lower serum hepcidin and greater parenchymal iron in nonalcoholic fatty liver disease patients with C282Y HFE mutations (pages 1730–1740)

      James E. Nelson, Elizabeth M. Brunt, Kris V. Kowdley and for the Nonalcoholic Steatohepatitis Clinical Research Network

      Article first published online: 20 SEP 2012 | DOI: 10.1002/hep.25856

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      Patients transplanted for nonalcoholic steatohepatitis are at increased risk for postoperative cardiovascular events (pages 1741–1750)

      Lisa B. VanWagner, Manali Bhave, Helen S. Te, Joe Feinglass, Lisa Alvarez and Mary E. Rinella

      Article first published online: 31 OCT 2012 | DOI: 10.1002/hep.25855

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      Histopathological algorithm and scoring system for evaluation of liver lesions in morbidly obese patients (pages 1751–1759)

      Pierre Bedossa, Christine Poitou, Nicolas Veyrie, Jean-Luc Bouillot, Arnaud Basdevant, Valerie Paradis, Joan Tordjman and Karine Clement

      Article first published online: 31 OCT 2012 | DOI: 10.1002/hep.25889

  4. Hepatobiliary Malignancies

    1. Top of page
    2. Editorials
    3. Viral Hepatitis
    4. Steatohepatitis/Metabolic Liver Disease
    5. Hepatobiliary Malignancies
    6. Autoimmune, Cholestatic and Biliary Disease
    7. Liver Failure/Cirrhosis/Portal Hypertension
    8. Liver Injury/Regeneration
    9. Liver Biology/Pathobiology
    10. Reviews
    11. Hepatology Elsewhere
    12. Clinical Observations in Hepatology
    13. Correspondence
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      The centrosomal protein tax1 binding protein 2 is a novel tumor suppressor in hepatocellular carcinoma regulated by cyclin-dependent kinase 2 (pages 1770–1781)

      Wai-Lung Lai, Wing-Yan Hung, Leo Lap-Yan Wong, Yuan Zhou, Veronica Yee-Law Leong, Joyce Man-Fong Lee, Irene Oi-Lin Ng, Dong-Yan Jin and Yick-Pang Ching

      Article first published online: 17 SEP 2012 | DOI: 10.1002/hep.25851

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      Astrocyte elevated gene-1 promotes hepatocarcinogenesis: Novel insights from a mouse model (pages 1782–1791)

      Jyoti Srivastava, Ayesha Siddiq, Luni Emdad, Prasanna Kumar Santhekadur, Dong Chen, Rachel Gredler, Xue-Ning Shen, Chadia L. Robertson, Catherine I. Dumur, Phillip B. Hylemon, Nitai D. Mukhopadhyay, Deepak Bhere, Khalid Shah, Rushdy Ahmad, Shah Giashuddin, Jillian Stafflinger, Mark A. Subler, Jolene J. Windle, Paul B. Fisher and Devanand Sarkar

      Article first published online: 31 OCT 2012 | DOI: 10.1002/hep.25868

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      Transcriptomic profiling reveals hepatic stem-like gene signatures and interplay of miR-200c and epithelial-mesenchymal transition in intrahepatic cholangiocarcinoma (pages 1792–1803)

      Naoki Oishi, Mia R. Kumar, Stephanie Roessler, Junfang Ji, Marshonna Forgues, Anuradha Budhu, Xuelian Zhao, Jesper B. Andersen, Qing-Hai Ye, Hu-Liang Jia, Lun-Xiu Qin, Taro Yamashita, Hyun Goo Woo, Yoon Jun Kim, Shuichi Kaneko, Zhao-You Tang, Snorri S. Thorgeirsson and Xin Wei Wang

      Article first published online: 22 AUG 2012 | DOI: 10.1002/hep.25890

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      Background progenitor activation is associated with recurrence after hepatectomy of combined hepatocellular-cholangiocarcinoma (pages 1804–1816)

      Xiong Cai, Jian Zhai, David E. Kaplan, Yijun Zhang, Lining Zhou, Xutao Chen, Guangyang Qian, Qiudong Zhao, Yonghai Li, Lu Gao, Wenming Cong, Minghua Zhu, Zhenlin Yan, Lehua Shi, Dong Wu, Lixin Wei, Feng Shen and Mengchao Wu

      Article first published online: 25 JUN 2012 | DOI: 10.1002/hep.25874

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      Methylome analysis and integrative profiling of human HCCs identify novel protumorigenic factors (pages 1817–1827)

      Olaf Neumann, Miriam Kesselmeier, Robert Geffers, Rossella Pellegrino, Bernhard Radlwimmer, Katrin Hoffmann, Volker Ehemann, Peter Schemmer, Peter Schirmacher, Justo Lorenzo Bermejo and Thomas Longerich

      Article first published online: 14 OCT 2012 | DOI: 10.1002/hep.25870

  5. Autoimmune, Cholestatic and Biliary Disease

    1. Top of page
    2. Editorials
    3. Viral Hepatitis
    4. Steatohepatitis/Metabolic Liver Disease
    5. Hepatobiliary Malignancies
    6. Autoimmune, Cholestatic and Biliary Disease
    7. Liver Failure/Cirrhosis/Portal Hypertension
    8. Liver Injury/Regeneration
    9. Liver Biology/Pathobiology
    10. Reviews
    11. Hepatology Elsewhere
    12. Clinical Observations in Hepatology
    13. Correspondence
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  6. Liver Failure/Cirrhosis/Portal Hypertension

    1. Top of page
    2. Editorials
    3. Viral Hepatitis
    4. Steatohepatitis/Metabolic Liver Disease
    5. Hepatobiliary Malignancies
    6. Autoimmune, Cholestatic and Biliary Disease
    7. Liver Failure/Cirrhosis/Portal Hypertension
    8. Liver Injury/Regeneration
    9. Liver Biology/Pathobiology
    10. Reviews
    11. Hepatology Elsewhere
    12. Clinical Observations in Hepatology
    13. Correspondence
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      Droxidopa, an oral norepinephrine precursor, improves hemodynamic and renal alterations of portal hypertensive rats (pages 1849–1860)

      Mar Coll, Sarai Rodriguez, Imma Raurell, Nahia Ezkurdia, Astrid Brull, Salvador Augustin, Jaime Guardia, Rafael Esteban, María Martell and Joan Genescà

      Article first published online: 14 OCT 2012 | DOI: 10.1002/hep.25845

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      Interaction between intestinal dendritic cells and bacteria translocated from the gut in rats with cirrhosis (pages 1861–1869)

      Leticia Muñoz, María José Borrero, María Ubeda, Margaret Lario, David Díaz, Rubén Francés, Jorge Monserrat, Óscar Pastor, Elia Aguado-Fraile, José Such, Melchor Álvarez-Mon and Agustín Albillos

      Article first published online: 17 SEP 2012 | DOI: 10.1002/hep.25854

  7. Liver Injury/Regeneration

    1. Top of page
    2. Editorials
    3. Viral Hepatitis
    4. Steatohepatitis/Metabolic Liver Disease
    5. Hepatobiliary Malignancies
    6. Autoimmune, Cholestatic and Biliary Disease
    7. Liver Failure/Cirrhosis/Portal Hypertension
    8. Liver Injury/Regeneration
    9. Liver Biology/Pathobiology
    10. Reviews
    11. Hepatology Elsewhere
    12. Clinical Observations in Hepatology
    13. Correspondence
    1. You have free access to this content
      Human antigen R contributes to hepatic stellate cell activation and liver fibrosis (pages 1870–1882)

      Ashwin Woodhoo, Marta Iruarrizaga-Lejarreta, Naiara Beraza, Juan L García-Rodríguez, Nieves Embade, David Fernández-Ramos, Nuria Martínez-López, Virginia Gutiérrez-De Juan, Beatriz Arteta, Juan Caballeria, Shelly C Lu, José M Mato, Marta Varela-Rey and María L Martínez-Chantar

      Article first published online: 9 OCT 2012 | DOI: 10.1002/hep.25828

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      Common genetic variation in vitamin D metabolism is associated with liver stiffness (pages 1883–1891)

      Frank Grünhage, Katrin Hochrath, Marcin Krawczyk, Aksana Höblinger, Barbara Obermayer-Pietsch, Jürgen Geisel, Michael Trauner, Tilman Sauerbruch and Frank Lammert

      Article first published online: 14 OCT 2012 | DOI: 10.1002/hep.25830

  8. Liver Biology/Pathobiology

    1. Top of page
    2. Editorials
    3. Viral Hepatitis
    4. Steatohepatitis/Metabolic Liver Disease
    5. Hepatobiliary Malignancies
    6. Autoimmune, Cholestatic and Biliary Disease
    7. Liver Failure/Cirrhosis/Portal Hypertension
    8. Liver Injury/Regeneration
    9. Liver Biology/Pathobiology
    10. Reviews
    11. Hepatology Elsewhere
    12. Clinical Observations in Hepatology
    13. Correspondence
    1. You have free access to this content
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      CD11b+ Gr1+ bone marrow cells ameliorate liver fibrosis by producing interleukin-10 in mice (pages 1902–1912)

      Yang-Gun Suh, Ja Kyung Kim, Jin-Seok Byun, Hyon-Seung Yi, Young-Sun Lee, Hyuk Soo Eun, So Yeon Kim, Kwang-Hyub Han, Kwan Sik Lee, Gregg Duester, Scott L. Friedman and Won-Il Jeong

      Article first published online: 9 OCT 2012 | DOI: 10.1002/hep.25817

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      Serine protease hepsin regulates hepatocyte size and hemodynamic retention of tumor cells by hepatocyte growth factor signaling in mice (pages 1913–1923)

      Yu-Chen Hsu, Hsiang-Po Huang, I-Shing Yu, Kang-Yi Su, Shu-Rung Lin, Wei-Chou Lin, Hua-Lin Wu, Guey-Yueh Shi, Mi-Hua Tao, Cheng-Heng Kao, Yao-Ming Wu, Patricia E. Martin, Shih-Yao Lin, Pan-Chyr Yang and Shu-Wha Lin

      Article first published online: 9 OCT 2012 | DOI: 10.1002/hep.25773

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      Liver sinusoidal endothelial cells contribute to CD8 T cell tolerance toward circulating carcinoembryonic antigen in mice (pages 1924–1933)

      Bastian Höchst, Frank A. Schildberg, Jan Böttcher, Christina Metzger, Sebastian Huss, Andreas Türler, Markus Overhaus, Andreas Knoblich, Berthold Schneider, Dimitrios Pantelis, Christian Kurts, Jörg C. Kalff, Percy Knolle and Linda Diehl

      Article first published online: 14 OCT 2012 | DOI: 10.1002/hep.25844

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      Megakaryocytes promote hepatoepithelial liver cell development in E11.5 mouse embryos by cell-to-cell contact and by vascular endothelial growth factor A signaling (pages 1934–1945)

      Natalia Serrano, Isabel Cortegano, Carolina Ruiz, Mario Alía, Belén de Andrés, María Teresa Rejas, Miguel A.R. Marcos and María Luisa Gaspar

      Article first published online: 27 AUG 2012 | DOI: 10.1002/hep.25853

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      Circulating microRNAs in exosomes indicate hepatocyte injury and inflammation in alcoholic, drug-induced, and inflammatory liver diseases (pages 1946–1957)

      Shashi Bala, Jan Petrasek, Shiv Mundkur, Donna Catalano, Ivan Levin, Jeanine Ward, Hawau Alao, Karen Kodys and Gyongyi Szabo

      Article first published online: 26 JUL 2012 | DOI: 10.1002/hep.25873

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      Chemokines and mitochondrial products activate neutrophils to amplify organ injury during mouse acute liver failure (pages 1971–1982)

      Pedro E. Marques, Sylvia S. Amaral, Daniele A. Pires, Laura L. Nogueira, Frederico M. Soriani, Braulio H.F. Lima, Gabriel A.O. Lopes, Remo C. Russo, Thiago V. Ávila, Juliana G. Melgaço, André G. Oliveira, Marcelo A. Pinto, Cristiano X. Lima, Ana Maria De Paula, Denise C. Cara, Maria F. Leite, Mauro M. Teixeira and Gustavo Batista Menezes

      Article first published online: 21 AUG 2012 | DOI: 10.1002/hep.25801

  9. Reviews

    1. Top of page
    2. Editorials
    3. Viral Hepatitis
    4. Steatohepatitis/Metabolic Liver Disease
    5. Hepatobiliary Malignancies
    6. Autoimmune, Cholestatic and Biliary Disease
    7. Liver Failure/Cirrhosis/Portal Hypertension
    8. Liver Injury/Regeneration
    9. Liver Biology/Pathobiology
    10. Reviews
    11. Hepatology Elsewhere
    12. Clinical Observations in Hepatology
    13. Correspondence
    1. You have free access to this content
      New therapeutic paradigm for patients with cirrhosis (pages 1983–1992)

      Emmanuel A. Tsochatzis, Jaime Bosch and Andrew K. Burroughs

      Article first published online: 31 OCT 2012 | DOI: 10.1002/hep.25915

  10. Hepatology Elsewhere

    1. Top of page
    2. Editorials
    3. Viral Hepatitis
    4. Steatohepatitis/Metabolic Liver Disease
    5. Hepatobiliary Malignancies
    6. Autoimmune, Cholestatic and Biliary Disease
    7. Liver Failure/Cirrhosis/Portal Hypertension
    8. Liver Injury/Regeneration
    9. Liver Biology/Pathobiology
    10. Reviews
    11. Hepatology Elsewhere
    12. Clinical Observations in Hepatology
    13. Correspondence
    1. You have free access to this content
    2. You have free access to this content
    3. You have free access to this content
  11. Clinical Observations in Hepatology

    1. Top of page
    2. Editorials
    3. Viral Hepatitis
    4. Steatohepatitis/Metabolic Liver Disease
    5. Hepatobiliary Malignancies
    6. Autoimmune, Cholestatic and Biliary Disease
    7. Liver Failure/Cirrhosis/Portal Hypertension
    8. Liver Injury/Regeneration
    9. Liver Biology/Pathobiology
    10. Reviews
    11. Hepatology Elsewhere
    12. Clinical Observations in Hepatology
    13. Correspondence
    1. You have free access to this content
  12. Correspondence

    1. Top of page
    2. Editorials
    3. Viral Hepatitis
    4. Steatohepatitis/Metabolic Liver Disease
    5. Hepatobiliary Malignancies
    6. Autoimmune, Cholestatic and Biliary Disease
    7. Liver Failure/Cirrhosis/Portal Hypertension
    8. Liver Injury/Regeneration
    9. Liver Biology/Pathobiology
    10. Reviews
    11. Hepatology Elsewhere
    12. Clinical Observations in Hepatology
    13. Correspondence
    1. You have free access to this content
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      Reply: (pages 2005–2006)

      Kiran Bambha and Nathan M. Bass

      Article first published online: 31 OCT 2012 | DOI: 10.1002/hep.25838

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      Metabolic oxidation controls the hepatic stem cells (HpSCs) fate and the hepatic lineage organization in physiologic and pathologic conditions (pages 2006–2007)

      Vincenzo Cardinale, Guido Carpino, Alfredo Cantafora, Lola M. Reid, Eugenio Gaudio and Domenico Alvaro

      Article first published online: 31 OCT 2012 | DOI: 10.1002/hep.25825

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      Reply: (page 2009)

      Naoki Tanaka and Frank J. Gonzalez

      Article first published online: 31 OCT 2012 | DOI: 10.1002/hep.25811

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      Elevated coffee consumption and reduced risk of insulin resistance in HIV-HCV coinfected patients (HEPAVIH ANRS CO-13) (page 2010)

      M. Patrizia Carrieri, Philippe Sogni, Julien Cohen, Marc-Arthur Loko, Maria Winnock, Bruno Spire and and the HEPAVIH Study Group

      Article first published online: 31 OCT 2012 | DOI: 10.1002/hep.25813

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      Hedgehog-responsive progenitors: Predictors of liver outcomes? (pages 2010–2011)

      Jason Coombes and Wing-Kin Syn

      Article first published online: 31 OCT 2012 | DOI: 10.1002/hep.25840

      Corrected by:

      Erratum: Correction

      Vol. 58, Issue 2, 838, Article first published online: 29 JAN 2013

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      Correspondence (page 2011)

      Pau Sancho-Bru, José Altamirano and Ramon Bataller

      Article first published online: 31 OCT 2012 | DOI: 10.1002/hep.25841

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