Research Article

New ent-Abietanoids from Isodon rubescens

  1. Quan-Bin Han1,
  2. Rong-Tao Li1,
  3. Ji-Xia Zhang2,
  4. Han-Dong Sun1

Article first published online: 26 APR 2004

DOI: 10.1002/hlca.200490072

Issue

Helvetica Chimica Acta

Helvetica Chimica Acta

Volume 87, Issue 4, pages 1007–1015, April 2004

Additional Information

How to Cite

Han, Q.-B., Li, R.-T., Zhang, J.-X. and Sun, H.-D. (2004), New ent-Abietanoids from Isodon rubescens. HCA, 87: 1007–1015. doi: 10.1002/hlca.200490072

Author Information

  1. 1

    State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650204, Yunnan, P.R. China (Phone: +86-871-522 32 51; fax: +86-871-521 63 43)

  2. 2

    Department of Chemistry, Xinxiang Medical College, Xinxiang 453000, Henan, P.R. China

Publication History

  1. Issue published online: 26 APR 2004
  2. Article first published online: 26 APR 2004
  3. Manuscript Received: 19 NOV 2003

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Abstract

Six new ent-abietane diterpenoids, rubescensins I–M (1–5) and P (6), along with two related acetonide derivatives (7 and 8), were isolated from Isodon rubescens. Their structures were elucidated by detailed spectroscopic analysis. Compound 5 is the first N-containing diterpenoid from the genus Isodon, exhibiting notable cytotoxicity against human tumor K562 cells.

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