Research Article

Cytotoxic Triterpenoid Saponins Acetylated with Monoterpenoid Acid from Albizia julibrissin

  1. Kun Zou1,2,
  2. Qing-Ying Zhang1,
  3. Bin Wang1,
  4. Jing-Rong Cui3,
  5. Yu-Ying Zhao1,
  6. Ru-Yi Zhang1

Article first published online: 20 OCT 2010

DOI: 10.1002/hlca.201000059

Issue

Helvetica Chimica Acta

Helvetica Chimica Acta

Volume 93, Issue 10, pages 2100–2106, October 2010

Additional Information

How to Cite

Zou, K., Zhang, Q.-Y., Wang, B., Cui, J.-R., Zhao, Y.-Y. and Zhang, R.-Y. (2010), Cytotoxic Triterpenoid Saponins Acetylated with Monoterpenoid Acid from Albizia julibrissin. HCA, 93: 2100–2106. doi: 10.1002/hlca.201000059

Author Information

  1. 1

    State Key Laboratory of Natural and Biomimetic Drugs and Department of Natural Medicines, School of Pharmaceutical Sciences, Peking University Health Science Center, Beijing 100191, P. R. China, (phone/fax: +86-10-82801725 (Qing-Ying Zhang); phone/fax: +86-10-82801592 (Yu-Ying Zhao))

  2. 2

    College of Chemistry and Life Sciences, China Three Gorges University, Yichang 443000, P. R. China

  3. 3

    State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University Health Science Center, Beijing 100191, P. R. China

Publication History

  1. Issue published online: 20 OCT 2010
  2. Article first published online: 20 OCT 2010
  3. Manuscript Received: 11 FEB 2010

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Keywords:

  • Albizia julibrissin;
  • Julibrosides J16, J17 , and J21

Abstract

Three new triterpenoid saponins, named julibroside J16 (2), julibroside J17 (3), and julibroside J21 (4), each of which possesses an oleanane triterpenoid aglycone of acacic acid, two monoterpenoid acids, and nine sugar moieties, together with one known saponin, julibroside II (1), were isolated from the stem bark of Albizia julibrissin by chromatographic methods. Their structures were established by chemical and spectroscopic means. Saponins 1, 2, and 4 showed inhibitory activities against Bel 7402 human cancer cell line in vitro.

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