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Absence of exon 15 BRAF germline mutations in familial melanoma†

  1. Julie Lang1,*,
  2. Maureen Boxer1,
  3. Rona MacKie2

Article first published online: 24 FEB 2003

DOI: 10.1002/humu.10188

Issue

Human Mutation

Human Mutation

Special Issue: Focus on p53 and Cancer

Volume 21, Issue 3, pages 327–330, March 2003

Additional Information

How to Cite

Lang, J., Boxer, M. and MacKie, R. (2003), Absence of exon 15 BRAF germline mutations in familial melanoma. Hum. Mutat., 21: 327–330. doi: 10.1002/humu.10188

Author Information

  1. 1

    Duncan Guthrie Institute of Medical Genetics, Yorkhill, Glasgow, UK

  2. 2

    Department of Public Health, University of Glasgow, Glasgow, UK

*Duncan Guthrie Institute of Medical Genetics, Yorkhill, Glasgow, UK

  1. †

    Communicated by Riccardo Fodde

Publication History

  1. Issue published online: 24 FEB 2003
  2. Article first published online: 24 FEB 2003
  3. Manuscript Accepted: 19 DEC 2002
  4. Manuscript Received: 13 SEP 2002

Funded by

  • The Shaw Charitable Trust

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REFERENCES

  • Bishop DT, Demenais F, Goldstein AM, Bergman W, Newton Bishop J, Bressac-de Paillerets B, Chompret A, Ghiorzo P, Gruis N, Hansson J, Harland M, Hayward N, Holland EA, Mann GJ, Mantelli M, Nancarrow D, Platz A, Tucker MA. 2002. Geographical variation in the penetrance of CDKN2A mutations for melanoma. J Natl Cancer Inst 94:894–903.
  • Davies H, Bignell GR, Cox C, Stephens P, Edkins S, Clegg S, Teague J, Woffendin H, Garnett MJ, Bottomley W, Davis N, Dicks E, Ewing R, Floyd Y, Gray K, Hall S, Hawes R, Hughes J, Kosmidou V, Menzies A, Mould C, Parker A, Stevens C, Watt S, Hooper S, Wilson R, Jayatilake H, Gusterson BA, Cooper C, Shipley J, Hargrave D, Pritchard-Jones K, Maitland N, Chenevix-Trench G, Riggins GJ, Bigner DD, Palmieri G, Cossu A, Flanagan A, Nicholson A, Ho JW, Leung SY, Yuen ST, Weber BL, Seigler HF, Darrow TL, Paterson H, Marais R, Marshall CJ, Wooster R, Stratton MR, Futreal PA. 2002. Mutations of the BRAF gene in human cancer. Nature 417:949–954.
  • Elwood JM, Jopson J. 1997. Melanoma and sun exposure: an overview of published studies. Int J Cancer 73:198–203.
    Direct Link:
  • Jemal A, Devesa SS, Hartge P, Tucker MA. 2001. Recent trends in cutaneous melanoma incidence among whites in the United States. J Natl Cancer Inst 93:678–683.
  • MacKie RM, Andrew N, Lanyon WG, Connor JM. 1998. CDKN2A germline mutations in U.K. patients with familial melanoma and multiple primary melanomas. J Invest Dermatol. 111:269–72.
  • MacKie RM, Bray CA, Hole DJ, Morris A, Nicolson M, Evans A, Doherty V, Vestey J. 2002. Incidence of and survival from malignant melanoma in Scotland: an epidemiological study. Lancet 360:587–591.
  • Marrett LD, Nguyen HL, Armstrong BK. 2001. Trends in the incidence of cutaneous malignant melanoma in New South Wales, 1983–1996. Int J Cancer 92:457–462.
    Direct Link:
  • Palmer JS, Duffy DL, Box NF, Aitken JF, O'Gorman LE, Green AC, Hayward NK, Martin NG, Sturm RA. 2000. Melanocortin-1 receptor polymorphisms and risk of melanoma: is the association explained solely by pigmentation phenotype? Am J Hum Genet 66:176–186.
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