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Research Article

Functional Characterization of Novel Mutations Affecting Survivin (BIRC5)-Mediated Therapy Resistance in Head and Neck Cancer Patients

  1. Shirley K. Knauer1,*,
  2. Britta Unruhe1,
  3. Sarah Karczewski1,
  4. Rouven Hecht1,
  5. Verena Fetz2,
  6. Carolin Bier2,
  7. Sandra Friedl2,
  8. Barbara Wollenberg3,
  9. Ralph Pries3,
  10. Negusse Habtemichael2,
  11. Ulf-Rüdiger Heinrich2,
  12. Roland H. Stauber2

Article first published online: 20 DEC 2012

DOI: 10.1002/humu.22249

Issue

Human Mutation

Human Mutation

Volume 34, Issue 2, pages 395–404, February 2013

Additional Information

How to Cite

Knauer, S. K., Unruhe, B., Karczewski, S., Hecht, R., Fetz, V., Bier, C., Friedl, S., Wollenberg, B., Pries, R., Habtemichael, N., Heinrich, U.-R. and Stauber, R. H. (2013), Functional Characterization of Novel Mutations Affecting Survivin (BIRC5)-Mediated Therapy Resistance in Head and Neck Cancer Patients. Hum. Mutat., 34: 395–404. doi: 10.1002/humu.22249

Author Information

  1. 1

    Institute for Molecular Biology, Centre for Medical Biotechnology (ZMB), Germany

  2. 2

    Department of Otorhinolaryngology, University Medical Center Mainz, Germany

  3. 3

    Department of Otorhinolaryngology, University Hospital of Schleswig-Holstein, Lübeck, Germany

*Correspondence to: Shirley K. Knauer, Institute for Molecular Biology, Centre for Medical Biotechnology (ZMB), University of Duisburg-Essen, Universitätsstr. 5, 45141 Essen, Germany. E-mail: shirley.knauer@uni-due.de

  1. Communicated by Bruce Gottlieb

  2. Contract grant sponsors: MAIFOR; German Research Foundation FKZ KN 973/1-1; Stiftung Tumorforschung Kopf-Hals; Carl-Zeiss foundation 3ChemBioMed2 priority program.

Publication History

  1. Issue published online: 29 JAN 2013
  2. Article first published online: 20 DEC 2012
  3. Accepted manuscript online: 15 NOV 2012 12:29PM EST
  4. Manuscript Accepted: 31 OCT 2012
  5. Manuscript Received: 1 JAN 2012

Funded by

  • MAIFOR
  • German Research Foundation. Grant Number: FKZ KN 973/1-1;
  • Stiftung Tumorforschung Kopf-Hals
  • Carl-Zeiss foundation

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