Research Article

Drastic Effect of Germline TP53 Missense Mutations in Li–Fraumeni Patients

  1. Yasmine Zerdoumi1,
  2. Juliette Aury-Landas1,
  3. Catherine Bonaïti-Pellié2,
  4. Céline Derambure3,
  5. Richard Sesboüé1,
  6. Mariette Renaux-Petel1,
  7. Thierry Frebourg1,4,*,
  8. Gaëlle Bougeard1,†,
  9. Jean-Michel Flaman1,†

Article first published online: 11 FEB 2013

DOI: 10.1002/humu.22254

Issue

Human Mutation

Human Mutation

Volume 34, Issue 3, pages 453–461, March 2013

Additional Information

How to Cite

Zerdoumi, Y., Aury-Landas, J., Bonaïti-Pellié, C., Derambure, C., Sesboüé, R., Renaux-Petel, M., Frebourg, T., Bougeard, G. and Flaman, J.-M. (2013), Drastic Effect of Germline TP53 Missense Mutations in Li–Fraumeni Patients. Hum. Mutat., 34: 453–461. doi: 10.1002/humu.22254

Author Information

  1. 1

    Inserm U1079, Institute for Research and Innovation in Biomedicine (IRIB), University of Rouen, Rouen, France

  2. 2

    Inserm U669, University of Paris Sud, Villejuif, France

  3. 3

    Inserm U905, Institute for Research and Innovation in Biomedicine (IRIB), University of Rouen, Rouen, France

  4. 4

    Department of Genetics, Rouen University Hospital, Rouen, France

  1. †

    These authors contributed equally to this work.

*Correspondence to: Thierry Frebourg, Inserm U1079, Faculty of Medicine, 22 Boulevard Gambetta, 76183 Rouen cedex, France. E-mail: Frebourg@chu-rouen.fr

  1. Additional Supporting Information may be found in the online version of this article.

  2. Communicated by Dominique Stoppa-Lyonnet

  3. †

    These authors contributed equally to this work.

Publication History

  1. Issue published online: 18 FEB 2013
  2. Article first published online: 11 FEB 2013
  3. Accepted manuscript online: 21 NOV 2012 02:05PM EST
  4. Manuscript Accepted: 14 NOV 2012
  5. Manuscript Received: 31 AUG 2012

Funded by

  • INCa, the French National Cancer Institute

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View Full Article with Supporting Information (HTML) Get PDF (427K)