Research was conducted at the Centre for Human Psychopharmacology, National Institute of Complementary Medicine (NICM) Collaborative Centre for Neurocognition, Swinburne University, Melbourne, VIC 3122, Australia.
The effect of multivitamin supplementation on mood and stress in healthy older men
Article first published online: 16 NOV 2011
Copyright © 2011 John Wiley & Sons, Ltd.
Human Psychopharmacology: Clinical and Experimental
Volume 26, Issue 8, pages 560–567, December 2011
How to Cite
Harris, E., Kirk, J., Rowsell, R., Vitetta, L., Sali, A., Scholey, A. B. and Pipingas, A. (2011), The effect of multivitamin supplementation on mood and stress in healthy older men. Hum. Psychopharmacol. Clin. Exp., 26: 560–567. doi: 10.1002/hup.1245
- Issue published online: 13 DEC 2011
- Article first published online: 16 NOV 2011
- Manuscript Accepted: 10 OCT 2011
- Manuscript Received: 21 FEB 2011
- multivitamin supplementation;
There is a demonstrated association between poor mood and deficiency in several micronutrients. Multivitamin supplements contain a wide range of nutrients, suggesting that they may be effective in improving mood; however, few studies have investigated this potential in randomized, controlled trials. This study investigates the effects of a multivitamin, mineral, and herbal supplement on mood and stress in a group of healthy, older male volunteers.
In this randomized, double-blind, placebo-controlled trial, fifty men, aged 50–69 years, supplemented for a period of 8 weeks with a multivitamin formulation that contained vitamins (at levels above recommended daily intakes), minerals, antioxidants, and herbal extracts, or a placebo. They completed a series of mood and stress questionnaires at baseline and post-supplementation.
Compared with placebo, there was a significant reduction in the overall score on a depression anxiety and stress scale and an improvement in alertness and general daily functioning in the multivitamin group.
Supplementation with a multivitamin, mineral and herbal formulation may be useful in improving alertness and reducing negative mood symptoms and may also improve feelings of general day-to-day well-being. Copyright © 2011 John Wiley & Sons, Ltd.