Epidemiology of inflammatory bowel disease in the Songpa-Kangdong district, Seoul, Korea, 1986–2005: A KASID study
Version of Record online: 16 OCT 2007
Copyright © 2007 Crohn's & Colitis Foundation of America, Inc.
Inflammatory Bowel Diseases
Volume 14, Issue 4, pages 542–549, April 2008
How to Cite
Yang, S.-K., Yun, S., Kim, J.-H., Park, J. Y., Kim, H. Y., Kim, Y.-H., Chang, D. K., Kim, J. S., Song, I. S., Park, J. B., Park, E.-R., Kim, K. J., Moon, G. and Yang, S. H. (2008), Epidemiology of inflammatory bowel disease in the Songpa-Kangdong district, Seoul, Korea, 1986–2005: A KASID study. Inflamm Bowel Dis, 14: 542–549. doi: 10.1002/ibd.20310
- Issue online: 12 MAR 2008
- Version of Record online: 16 OCT 2007
- Manuscript Accepted: 11 SEP 2007
- Manuscript Received: 27 JUN 2007
- Crohn's disease;
- ulcerative colitis;
Background: Crohn's disease (CD) and ulcerative colitis (UC) are considered rare diseases in developing countries. We have evaluated the incidence and prevalence of CD and UC over time in a district of Seoul, Korea.
Methods: A population-based study was performed from 1986 to 2005 in the Songpa-Kangdong district of Seoul. To recruit patients as completely as possible, multiple information sources, including all medical facilities in the study area and 3 referral centers nearby but outside the study area, were used.
Results: During the 20-year study period, 138 incident cases of CD (102 men, 36 women) and 341 incident cases of UC (170 men, 171 women) were identified. For the 20-year period, the adjusted mean annual incidence rates of CD and UC per 100,000 inhabitants were 0.53 (95% CI 0.44–0.62) and 1.51 (95% CI 1.34–1.67), respectively. When analyzed by 5-year intervals, the mean annual incidence rates of CD and UC increased significantly, from 0.05 and 0.34 per 100,000 inhabitants, respectively, in 1986–1990 to 1.34 and 3.08 per 100,000 inhabitants, respectively, in 2001–2005. The adjusted prevalence rates of CD and UC per 100,000 inhabitants on December 31, 2005, were 11.24 (95% CI 9.29–13.18) and 30.87 (95% CI 27.47–34.27), respectively.
Conclusions: The incidence and prevalence of CD and UC in Seoul, Korea, are still low compared with those in Western countries, but are rapidly increasing.
(Inflamm Bowel Dis 2007)