Partially funded by Crohn's and Colitis Australia.
Ability of commonly used prediction equations to predict resting energy expenditure in children with inflammatory bowel disease†
Article first published online: 4 NOV 2010
Copyright © 2010 Crohn's & Colitis Foundation of America, Inc.
Inflammatory Bowel Diseases
Volume 17, Issue 7, pages 1587–1593, July 2011
How to Cite
Hill, R. J., Lewindon, P. J., Withers, G. D., Connor, F. L., Ee, L. C., Cleghorn, G. J. and Davies, P. S.W. (2011), Ability of commonly used prediction equations to predict resting energy expenditure in children with inflammatory bowel disease. Inflamm Bowel Dis, 17: 1587–1593. doi: 10.1002/ibd.21518
- Issue published online: 14 JUN 2011
- Article first published online: 4 NOV 2010
- Manuscript Accepted: 7 SEP 2010
- Manuscript Received: 29 JUL 2010
- Crohn's disease;
- ulcerative colitis;
- resting energy expenditure
Paediatric onset inflammatory bowel disease (IBD) may cause alterations in energy requirements and invalidate the use of standard prediction equations. Our aim was to evaluate four commonly used prediction equations for resting energy expenditure (REE) in children with IBD.
Sixty-three children had repeated measurements of REE as part of a longitudinal research study yielding a total of 243 measurements. These were compared with predicted REE from Schofield, Oxford, FAO/WHO/UNU, and Harris–Benedict equations using the Bland–Altman method.
Mean (±SD) age of the patients was 14.2 (2.4) years. Mean measured REE was 1566 (336) kcal per day compared with 1491 (236), 1441 (255), 1481 (232), and 1435 (212) kcal per day calculated from Schofield, Oxford, FAO/WHO/UNU, and Harris–Benedict, respectively. While the Schofield equation demonstrated the least difference between measured and predicted REE, it, along with the other equations tested, did not perform uniformly across all subjects, indicating greater errors at either end of the spectrum of energy expenditure. Smaller differences were found for all prediction equations for Crohn's disease compared with ulcerative colitis.
Of the commonly used equations, the equation of Schofield should be used in pediatric patients with IBD when measured values are not able to be obtained. (Inflamm Bowel Dis 2010;)