Supported by IBDWG GI Fellows Award 2011-12 (to C.H.).
Micronutrient deficiencies in inflammatory bowel disease: From A to zinc†
Article first published online: 5 APR 2012
Copyright © 2012 Crohn's & Colitis Foundation of America, Inc.
Inflammatory Bowel Diseases
Volume 18, Issue 10, pages 1961–1981, October 2012
How to Cite
Hwang, C., Ross, V. and Mahadevan, U. (2012), Micronutrient deficiencies in inflammatory bowel disease: From A to zinc. Inflamm Bowel Dis, 18: 1961–1981. doi: 10.1002/ibd.22906
- Issue published online: 13 SEP 2012
- Article first published online: 5 APR 2012
- Manuscript Accepted: 11 JAN 2012
- Manuscript Received: 21 DEC 2011
- inflammatory bowel disease;
- micronutrient deficiencies
Inflammatory bowel disease (IBD) has classically been associated with malnutrition and weight loss, although this has become less common with advances in treatment and greater proportions of patients attaining clinical remission. However, micronutrient deficiencies are still relatively common, particularly in CD patients with active small bowel disease and/or multiple resections. This is an updated literature review of the prevalence of major micronutrient deficiencies in IBD patients, focusing on those associated with important extraintestinal complications, including anemia (iron, folate, vitamin B12) bone disease (calcium, vitamin D, and possibly vitamin K), hypercoagulability (folate, vitamins B6, and B12), wound healing (zinc, vitamins A and C), and colorectal cancer risk (folate and possibly vitamin D and calcium). (Inflamm Bowel Dis 2012)