Supported by grants from Fondo de Investigación Sanitaria (FIS 07/0475) from Ministerio de Ciencia e Innovación (SAF 06-06084; 09-07319), Fundació Gastroenterologia Dr. Francisco Vilardell (F05-01), Ministerio de Educación y Ciencia Spanish Networks RTICCC (RD06/0020/1050), 2009SGR290 and Fundación Científica de la Asociación Española contra el Cáncer.
Novel methylation panel for the early detection of neoplasia in high-risk ulcerative colitis and Crohn's colitis patients†
Article first published online: 24 APR 2012
Copyright © 2012 Crohn's & Colitis Foundation of America, Inc.
Inflammatory Bowel Diseases
How to Cite
Azuara, D., Rodriguez-Moranta, F., de Oca, J., Sanjuan, X., Guardiola, J., Lobaton, T., Wang, A., Boadas, J., Piqueras, M., Monfort, D., Galter, S., Esteller, M., Moreno, V. and Capellá, G. (2012), Novel methylation panel for the early detection of neoplasia in high-risk ulcerative colitis and Crohn's colitis patients. Inflamm Bowel Dis. doi: 10.1002/ibd.22994
- Article first published online: 24 APR 2012
- Manuscript Accepted: 28 MAR 2012
- Manuscript Received: 9 MAR 2012
Additional Supporting Information may be found in the online version of this article.
|IBD_22994_sm_suppinfofig1.tif||4037K||Supporting Figure 1. Analytical sensitivity of methylated TGFB2, SLIT2, HS3ST2 and TMEFF2 promoter by Methylation-Specific Melting Curve Analysis (MS-MCA). Graphs depicts the melting peaks for the different dilutions of methylated and unmethylated DNA. The increase in the height of the unmethylated peak and the corresponding decrease in the methylated one is evident as the percentage of methylated allele declines.|
|IBD_22994_sm_suppinfotab1.doc||31K||Supporting Information Table|
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