• 1
    Tran Y, Bogler O, Gorse K, Wieland I, Green M, Newsham I. A novel member of the NF2/ERM/4.1 superfamily with growth suppressing properties in lung cancer. Cancer Res 1999;56: 3543.
  • 2
    T ran Y, Benbatoul K, Gorse K, Rempel SA, Futreal A, Green MR, Newsham IF. Novel region of allelic deletion on chromosome 18p in tumors of the lung, brain and breast. Oncogene 1998;17: 3499505.
  • 3
    Kittiniyom K, Gorse KM, Dalbegue F, Lichy JH, Taubenberger JK, Newsham IF. Allelic loss on chromosome band 18p11.3 occurs early and reveals heterogeneity in breast cancer progression. Breast Cancer Res 2001;3: 1928.
  • 4
    Gutmann DH, Donahoe J, Perry A, Lemke N, Gorse K, Kittiniyom K, Rempel SA, Gutierrez J, Newsham IF. Loss of DAL-1, a protein 4.1-related tumor suppressor, is an important early event in the pathogenesis of meningiomas. Hum Mol Genet 2000;9: 1495500.
  • 5
    Bissell MJ, Weaver VM, Lelievre SA, Wang F, Petersen OW, Schmeichel KL. Tissue structure, nuclear organization, and gene expression in normal and malignant breast. Cancer Res 1999;59: 175763.
  • 6
    Blackwood MA, Weber BL. Recent advances in breast cancer biology. Curr Opin Oncol 1996;8: 44954.
  • 7
    Weaver VM, Petersen OW, Wang F, Larabell CA, Briand P, Damsky C, Bissell MJ. Reversion of the malignant phenotype of human breast cells in three-dimensional culture and in vivo by integrin blocking antibodies. J Cell Biol 1997;137: 23145.
  • 8
    Moll R, Mitze M, Frixen UH, Birchmeier W. Differential loss of E-cadherin expression in infiltrating ductal and lobular breast carcinomas. Am J Pathol 1993;143: 173142.
  • 9
    Birchmeier W, Hulsken J, Behrens J. Adherens junction proteins in tumour progression. Cancer Surv 1995;24: 12940.
  • 10
    Yap AS. The morphogenetic role of cadherin cell adhesion molecules in human cancer: a thematic review. Cancer Invest 1998;16: 25261.
  • 11
    Birchmeier W, Behrens J. Cadherin expression in carcinomas: role in the formation of cell junctions and the prevention of invasiveness. Biochim Biophys Acta 1994;1198: 1126.
  • 12
    Luna EJ, Hitt AL. Cytoskeleton-plasma membrane interactions. Science 1992;258: 95564.
  • 13
    Cowin P, Burke B. Cytoskeleton-membrane interactions [Published erratum appears in Curr Opin Cell Biol 1996;8:following 244]. Curr Opin Cell Biol 1996;8: 5665.
  • 14
    Sainio M, Zhao F, Heiska L, Turunen O, den Bakker M, Zwarthoff E, Lutchman M, Rouleau GA, Jaaskelainen J, Vaheri A, Carpen O. Neurofibromatosis 2 tumor suppressor protein colocalizes with ezrin and CD44 and associates with actin-containing cytoskeleton. J Cell Sci 1997;110: 224960.
  • 15
    den Bakker MA, Tascilar M, Riegman PH, Hekman AC, Boersma W, Janssen PJ, de Jong TA, Hendriks W, van der Kwast TH, Zwarthoff EC. Neurofibromatosis type 2 protein co-localizes with elements of the cytoskeleton. Am J Pathol 1995;147: 133949.
  • 16
    McCloskey DE, Armstrong DK, Jackisch C, Davidson NE. Programmed cell death in human breast cancer cells. Recent Prog Horm Res 1996;51: 493508.
  • 17
    Werb Z, Sympson CL, Alexander CM, Thomasset N, Lund LR, MacAuley A, Ashkenas J, Bissell MJ. Extracellular matrix remodeling and the regulation of epithelial-stromal interactions during differentiation and involution. Kidney Int Suppl 1996;54: S6874.
  • 18
    Petersen O, Ronnov-Jessen L, Weaver VM, Bissell MJ. Differentiation and cancer in the mammary gland: shedding light on an old dichotomy. Adv Cancer Res 1998;75: 13561.
  • 19
    Ley-Strumpf N, Kimichi A. Death associated proteins (DAPs): from gene identification to the analysis of their apoptotic and tumor suppressive functions. Oncogene 1998;17: 333140.
  • 20
    Knepper-Nicolai B, Savill J, Brown SB. Constitutive apoptosis in human neutrophils requires synergy between calpains and the proteosome downstream of caspases. J Biol Chem 1998;273: 305306.
  • 21
    Kondo T, Takeuchi K, Doi Y, Yonemura S, Nagata S, Tsukita S. ERM (ezrin/radixin/moesin)-based molecular mechanism of microvillar breakdown at an early stage of apoptosis. J Cell Biol 1997;139: 74958.
  • 22
    Mitra P, Keese CR, Giaever I. Electric measurements can be used to monitor the attachment and spreading of cells in tissue culture. Biotechniques 1991;11: 50410.
  • 23
    Tiruppathi C, Malik AB, Del Vecchio PJ, Keese CR, Giaever I. Electrical method for detection of endothelial cell shape change in real time: assessment of endothelial barrier function. Proc Natl Acad Sci USA 1992; 89: 791923.
  • 24
    Lo CM, Keese CR, Giaever I. Impedance analysis of MDCK cells measured by electric cell-substrate impedance sensing. Biophys J 1995;69: 28007.
  • 25
    Gutmann DH, Hirbe AC, Huang Z-Y, Haipek CA. The protein 4.1 tumor suppressor DAL-1 impairs cell spreading and motility, but regulates proliferation in a cell type-specific fashion. Neurobiol Dis 2001;8: 26678.
  • 26
    Hiscox S, Jiang WG. Ezrin regulates cell-cell and cell-matrix adhesion, a possible role with E-cadherin/β-catenin. J Cell Sci 1999;112: 308190.
  • 27
    Gutmann DH, Sherman L, Seftor L, Haipek C, Hoang Lu K, Hendrix M. Increased expression of the NF2 tumor suppressor gene product, Merlin, impairs cell motility, adhesion and spreading. Hum Mol Genet 1999;8: 26775.
  • 28
    Koga H, Araki N, Takeshima H, Nishi T, Hirota T., Kimura Y, Nakao M, Saya H. Impairment of cell adhesion by expression of the mutant neurofibromatosis type 2 (NF2) genes which lack exons in the ERM-homology domain. Oncogene 1998; 17: 80110.
  • 29
    Huynh DP, Pulst SM. Neurofibromatosis 2 antisense oligodeoxynucleotides induce reversible inhibition of schwannomin synthesis and cell adhesion in STS26T and T98G cells. Oncogene 1996;13: 7384.
  • 30
    Xu H-M, Gutmann DH. Merlin differentially associates with the microtubule and actin cytoskeleton. J Neurosci Res 1998;51: 40315.
  • 31
    Wegener J, Keese CR, Giaever I. Electrical cell-substrate impedance sensing (ECIS) as a noninvasive means to monitor the kinetics of cell spreading to artificial surfaces. Exp Cell Res 2000;259: 15868.
  • 32
    Shaw RJ, McClatchey AI, Jacks T. Regulation of the neurofibromatosis type 2 tumor suppressor protein merlin by adhesion and growth arrest stimuli. J Biol Chem 1998;273: 775764.
  • 33
    Frisch SM, Francis H. Disruption of epithelial cell-matrix interactions induces apoptosis. J Cell Biol 1994;124: 61926.
  • 34
    Eastman A, Rigas JR. Modulation of apoptosis signaling pathways and cell cycle regulation. Semin Oncol 1999;26: 716.
  • 35
    Tsukita S, Oishi K, Sato N, Sagara J, Kawai, Tsukita S. ERM family members as molecular linkers between the cell surface glycoprotein CD44 and actin-based cytoskeletons. J Cell Biol 1994;126: 391401.
  • 36
    Hirao M, Sato N, Kondo T, Yonemura S, Monden M, Sasaki T, Takai J, Tsukita S, Tsukita S. Regulation mechanism of ERM (ezrin/radixin/moesin) protein/plasma membrane association: possible involvement of phosphatidylinositol turnover and Rho-dependent signaling pathway. J Cell Biol 1996;135: 3751.
  • 37
    Goutebroze L, Brault E, Muchardt C, Camonis J, Thomas G. Cloning and characterization of SCHIP-1, a novel protein interacting specifically with spliced isoforms and naturally occurring mutant NF2 proteins. Mol Cell Biol 2000;20: 1699712.
  • 38
    Scoles DR, Huynh DO, Morcos PA, Coulsell ER, Robinson NGG, Tamanoi F, Pulst SM. Neurofibromatosis 2 tumor suppressor schwannomin interacts with βII-spectrin. Nat Genet 1998;18: 3549.
  • 39
    Murthy A, Gonzalez-Agosti C, Cordero E, Pinney D, Candice C, Solomon F, Gusella J, Ramesh V. NHE-RF, a regulatory cofactor for Na+-H+ exchange is a common interactor for merlin and ERM (MERM) proteins. J Biol Chem 1999;273: 12736.