Epidemiology

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Does pizza protect against cancer?

  1. Silvano Gallus1,†,*,
  2. Cristina Bosetti1,
  3. Eva Negri1,
  4. Renato Talamini2,
  5. Maurizio Montella3,
  6. Ettore Conti4,
  7. Silvia Franceschi5,
  8. Carlo La Vecchia1,6

Article first published online: 21 JUL 2003

DOI: 10.1002/ijc.11382

Issue

International Journal of Cancer

International Journal of Cancer

Volume 107, Issue 2, pages 283–284, 1 November 2003

Additional Information

How to Cite

Gallus, S., Bosetti, C., Negri, E., Talamini, R., Montella, M., Conti, E., Franceschi, S. and La Vecchia, C. (2003), Does pizza protect against cancer?. Int. J. Cancer, 107: 283–284. doi: 10.1002/ijc.11382

Author Information

  1. 1

    Istituto di Ricerche Farmacologiche “Mario Negri,” Milan, Italy

  2. 2

    Centro di Riferimento Oncologico, Aviano (PN), Italy

  3. 3

    Istituto Tumori “Fondazione Pascale,” Cappella dei Cangiani, Naples, Italy

  4. 4

    Istituto “Regina Elena” per lo Studio e la Cura dei Tumori, Rome, Italy

  5. 5

    International Agency for Research on Cancer, Lyon, France

  6. 6

    Istituto di Statistica Medica e Biometria, Università degli Studi di Milano, Milan, Italy

  1. †

    Fax: +39-02 33200231

*Istituto di Ricerche Farmacologiche “Mario Negri,” Via Eritrea, 62, 20157-Milan, Italy

  1. †

    Fax: +39-02 33200231

Publication History

  1. Issue published online: 26 AUG 2003
  2. Article first published online: 21 JUL 2003
  3. Manuscript Accepted: 20 MAY 2003
  4. Manuscript Revised: 5 MAY 2003
  5. Manuscript Received: 18 MAR 2003

Funded by

  • Italian Association for Cancer Research
  • Italian League Against Cancer

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Keywords:

  • digestive tract cancers;
  • lycopene;
  • pizza;
  • risk factors

Abstract

We analyzed the potential role of pizza on cancer risk, using data from an integrated network of case-control studies conducted in Italy between 1991 and 2000. Cancer sites were: oral cavity and pharynx (598 cases), esophagus (304 cases), larynx (460 cases), colon (1,225 cases) and rectum (728 cases). Controls were 4,999 patients admitted for acute, non-neoplastic conditions to the same hospital network as cases. Odds ratios for regular pizza consumers were 0.66 (95% confidence interval, CI = 0.47–0.93) for oral and pharyngeal cancer, 0.41 (95% CI = 0.25–0.69) for oesophageal, 0.82 (95% CI = 0.56–1.19) for laryngeal, 0.74 (95% CI = 0.61–0.89) for colon and 0.93 (95% CI = 0.75–1.17) for rectal cancer. Pizza appears therefore to be a favorable indicator of risk for digestive tract neoplasms in this population. © 2003 Wiley-Liss, Inc.

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