• 1
    Wood RD, Mitchell M, Sgouros J, Lindahl T. Human DNA repair genes. Science 2001; 291: 12849.
  • 2
    Shields PG, Harris CC. Cancer risk and low-penetrance susceptibility genes in gene-environment interactions. J Clin Oncol 2000; 18: 230915.
  • 3
    Goode EL, Ulrich CM, Potter JD. Polymorphisms in DNA repair genes and associations with cancer risk. Cancer Epidemiol Biomarkers Prev 2002; 11: 151330.
  • 4
    Mohrenweiser HW, Wilson DM III, Jones IM. Challenges and complexities in estimating both the functional impact and the disease risk associated with the extensive genetic variation in human DNA repair genes. Mutat Res 2003; 526: 93125.
  • 5
    Schottenfeld D. Epidemiology of lung cancer. In: Pass HI, Mitchell JB, Johnson DH, Turrisi AT, eds. Lung cancer: principles and practice Philadelphia: Lippincott-Raven Publishers, 1996. 30521.
  • 6
    Amos CI, Xu W, Spitz MR. Is there a genetic basis for lung cancer susceptibility? Rec Results Cancer Res 1999; 151: 312.
  • 7
    Lichtenstein P, Holm NV, Verkasalo PK, Iliadou A, Kaprio J, Koskenvuo M, Pukkala E, Skytthe A, Hemminki K. Environmental and heritable factors in the causation of cancer: analyses of cohorts of twins from Sweden, Denmark, and Finland. N Engl J Med 2000; 343: 7885.
  • 8
    Spitz MR, Wei Q, Dong Q, Amos CI, Wu X. Genetic susceptibility to lung cancer: the role of DNA damage and repair. Cancer Epidemiol Biomarkers Prev 2003; 12: 68998.
  • 9
    Wynder EL, Hoffmann D. Smoking and lung cancer: scientific challenges and opportunities. Cancer Res 1994; 54: 528495.
  • 10
    Gazdar AF, Minna JD. Cigarettes, sex, and lung adenocarcinoma. J Natl Cancer Inst 1997; 89: 15635.
  • 11
    Tanabe C, Aoyagi K, Sakiyama T, Kohno T, Yanagitani N, Akimoto S, Sakamoto M, Sakamoto H, Yokota J, Ohki M, Terada M, Yoshida T, et al. Evaluation of a whole-genome amplification method based on adaptor-ligation PCR of randomly sheared genomic DNA. Genes Chromosomes Cancer 2003; 38: 16876.
  • 12
    Travis WD, Colby TV, Corrin B, Shimosato Y, Brambilla E. Histological typing of lung and pleural tumours: World Health Organization International Histological Classification of Tumours. Berlin: Springer, 1999.
  • 13
    Yoshimi I, Ohshima A, Ajiki W, Tsukuma H, Sobue TA. Comparison of trends in the incidence rate of lung cancer by histological type in the Osaka Cancer Registry, Japan and in the Surveillance, Epidemiology and End Results Program, USA. Jpn J Clin Oncol 2003; 33: 98104.
  • 14
    Yanagitani N, Kohno T, Sunaga N, Kunitoh H, Tamura T, Tsuchiya S, Saito R, Yokota J. Localization of a human lung adenocarcinoma susceptibility locus, possibly syntenic to the mouse Pas1 locus, in the vicinity of the D12S1034 locus on chromosome 12p11.2-p12.1. Carcinogenesis 2002; 23: 117783.
  • 15
    Alderborn A, Kristofferson A, Hammerling U. Determination of single-nucleotide polymorphisms by real-time pyrophosphate DNA sequencing. Genome Res 2000; 10: 124958.
  • 16
    Breslow NE, Day NE. Statistical methods in cancer research: I, the analysis of case-control studies. IARC Sci Publ 1980; 32: 5338.
  • 17
    Mohrenweiser HW, Xi T, Vazquez-Matias J, Jones IM. Identification of 127 amino acid substitution variants in screening 37 DNA repair genes in humans. Cancer Epidemiol Biomarkers Prev 2002; 11: 105464.
  • 18
    Collins FS, Brooks LD, Chakravarti A. A DNA polymorphism discovery resource for research on human genetic variation. Genome Res 1998; 8: 122931.
  • 19
    Packer BR, Yeager M, Staats B, Welch R, Crenshaw A, Kiley M, Eckert A, Beerman M, Miller E, Bergen A, Rothman N, Strausberg R, et al. SNP500Cancer: a public resource for sequence validation and assay development for genetic variation in candidate genes. Nucl Acids Res 2004; 32: D52832.
  • 20
    Hirakawa M, Tanaka T, Hashimoto Y, Kuroda M, Takagi T, Nakamura Y. JSNP: a database of common gene variations in the Japanese population. Nucl Acids Res 2002; 30: 15862.
  • 21
    Houlston RS, Tomlinson IP. Detecting low penetrance genes in cancer: the way ahead. J Med Genet 2000; 37: 1617.
  • 22
    Goldgar DE. Population aspects of cancer genetics. Biochimie 2002; 84: 1925.
  • 23
    Hou SM, Falt S, Angelini S, Yang K, Nyberg F, Lambert B, Hemminki K. The XPD variant alleles are associated with increased aromatic DNA adduct level and lung cancer risk. Carcinogenesis 2002; 23: 599603.
  • 24
    Fan R, Wu M-T, Miller D, Wain JC, Kelsey KT, Wiencke JK, Christiani DC. The p53 codon 72 polymorphism and lung cancer risk. Cancer Epidemiol Biomarkers Prev 2000; 9: 103742.
  • 25
    Wu X, Zhao H, Amos CI, Shete S, Makan N, Hong WK, Kadlubar FF, Spitz MR. p53 genotypes and haplotypes associated with lung cancer susceptibility and ethnicity. J Natl Cancer Inst 2002; 94: 68190.
  • 26
    Dumont P, Leu JI, Della PAC III, George DL, Murphy M. The codon 72 polymorphic variants of p53 have markedly different apoptotic potential. Nat Genet 2003; 33: 35765.
  • 27
    Lee GH, Nishimori H, Sasaki Y, Matsushita H, Kitagawa T, Tokino T. Analysis of lung tumorigenesis in chimeric mice indicates the pulmonary adenoma resistance 2 (Par2) locus to operate in the tumor-initiation stage in a cell-autonomous manner: detection of polymorphisms in the Poli gene as a candidate for Par2. Oncogene 2003; 22: 237482.
  • 28
    Park J, Chen L, Tockman MS, Elahi A, Lazarus P. The human 8-oxoguanine DNA N-glycosylase 1 (hOGG1) DNA repair enzyme and its association with lung cancer risk. Pharmacogenetics 2004; 14: 1039.