Epidemiology

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Dietary patterns and subsequent colorectal cancer risk by subsite: A prospective cohort study

  1. Mi Kyung Kim1,2,
  2. Satoshi Sasaki1,3,
  3. Tetsuya Otani1,
  4. Shoichiro Tsugane1,†,*,
  5. for the Japan Public Health Center-based Prospective Study Group

Article first published online: 9 FEB 2005

DOI: 10.1002/ijc.20943

Issue

International Journal of Cancer

International Journal of Cancer

Volume 115, Issue 5, pages 790–798, 10 July 2005

Additional Information

How to Cite

Kim, M. K., Sasaki, S., Otani, T., Tsugane, S. and for the Japan Public Health Center-based Prospective Study Group (2005), Dietary patterns and subsequent colorectal cancer risk by subsite: A prospective cohort study. International Journal of Cancer, 115: 790–798. doi: 10.1002/ijc.20943

Author Information

  1. 1

    Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, Tokyo, Japan

  2. 2

    Division of Cancer Control and Epidemiology, National Cancer Center, Kyunggido, Korea

  3. 3

    National Institute of Health and Nutrition, Tokyo, Japan

  1. †

    Fax: +81-3-3547-8578.

*Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, 5-1-1 Tsukiji, Chuo-ku, Tokyo 104-0045, Japan

Publication History

  1. Issue published online: 11 MAY 2005
  2. Article first published online: 9 FEB 2005
  3. Manuscript Accepted: 9 DEC 2004
  4. Manuscript Received: 6 SEP 2004

Funded by

  • Grant in Aid for Cancer Research and Second-Term Comprehensive 10-Year Strategy for Cancer Control, the Ministry of Health, Labor and Welfare of Japan

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Keywords:

  • dietary pattern;
  • colorectal cancer;
  • subsite;
  • Japan

Abstract

In order to investigate the associations between dietary patterns and the risk of colorectal cancer by subsite in Japan, the baseline data from a population-based cohort study of 20,300 men and 21,812 women were analyzed. We conducted factor analysis and identified 3 major dietary patterns, “healthy,” “traditional” and “Western,” and calculated the factor scores of each pattern for individuals. During 10 years of follow-up, 370 colorectal cancer cases were identified. We found a positive association between the traditional pattern and colon cancer risk in women [rate ratio for highest quartile (RR) = 2.06; 95% CI = 1.10–3.84; p for trend = 0.11], but not in men. This positive association was slightly stronger for proximal colon cancer (RR = 2.07; 95% CI = 0.84–5.12) than for distal colon cancer (RR = 1.84; 95% CI = 0.75–4.50). After multivariate adjustment, the Western dietary pattern was also positively associated with colon cancer risk in females (RR = 2.21; 95% CI = 1.10–4.45), with the strongest associations being observed for females with distal colon cancer (RR = 3.48; 95% CI = 1.25–9.65). We did not observe any significant association between the healthy dietary pattern and colon cancer risk. For rectal cancer, no significant associations were found for the 3 dietary patterns. In conclusion, we found that the traditional and the Western dietary patterns were positively associated with colon cancer risk in females. © 2005 Wiley-Liss, Inc.

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