Fax: +90-312-266-5097.
Cancer Cell Biology
You have full text access to this OnlineOpen article
Lithium-mediated downregulation of PKB/Akt and cyclin E with growth inhibition in hepatocellular carcinoma cells
Article first published online: 18 FEB 2005
DOI: 10.1002/ijc.20972
Copyright © 2005 Wiley-Liss, Inc.
Additional Information
How to Cite
Erdal, E., Ozturk, N., Cagatay, T., Eksioglu-Demiralp, E. and Ozturk, M. (2005), Lithium-mediated downregulation of PKB/Akt and cyclin E with growth inhibition in hepatocellular carcinoma cells. Int. J. Cancer, 115: 903–910. doi: 10.1002/ijc.20972
Publication History
- Issue published online: 12 MAY 2005
- Article first published online: 18 FEB 2005
- Manuscript Accepted: 16 NOV 2004
- Manuscript Received: 22 SEP 2004
Funded by
- TUBITAK
- Turkish Association for Research and Fight against Cancer
- Bilkent University and Turkish Academy of Sciences (TUBA)
- Abstract
- Article
- References
- Cited By
Cited in:
- CrossRef
This article has been cited by:
- 1, , , Lithium reverses increased rates of cerebral protein synthesis in a mouse model of fragile X syndrome, Neurobiology of Disease, 2012, 45, 3, 1145
- 2, , , , , Citrus Flavonoids Luteolin, Apigenin, and Quercetin Inhibit Glycogen Synthase Kinase-3β Enzymatic Activity by Lowering the Interaction Energy Within the Binding Cavity, Journal of Medicinal Food, 2011, 14, 4, 325
- 3, , , , , , , , , Interaction networks of lithium and valproate molecular targets reveal a striking enrichment of apoptosis functional clusters and neurotrophin signaling, The Pharmacogenomics Journal, 2011,
- 4, , , , , , , , , Inhibition of Akt signaling in hepatoma cells induces apoptotic cell death independent of Akt activation status, Investigational New Drugs, 2010, 29, 6, 1303
- 5, , , , , , Role of GSK-3β in hepatocellular carcinoma cell migration, Academic Journal of Second Military Medical University, 2010, 30, 1, 28
- 6, , , , , , Transforming growth factor-beta induces senescence in hepatocellular carcinoma cells and inhibits tumor growth, Hepatology, 2010, 52, 3Direct Link:
- 7, , , , , , A molecular study of pathways involved in the inhibition of cell proliferation in neuroblastoma B65 cells by the GSK-3 inhibitors lithium and SB-415286, Journal of Cellular and Molecular Medicine, 2009, 13, 9bDirect Link:
- 8, Glycogen synthase kinase 3β (GSK3β) in tumorigenesis and cancer chemotherapy, Cancer Letters, 2009, 273, 2, 194
- 9, , , , , , , Glycogen synthase kinase-3 is involved in the regulation of the cell cycle in cerebellar granule cells, Neuropharmacology, 2007, 53, 2, 295
- 10, , , , , , Lithium suppresses cell proliferation by interrupting E2F–DNA interaction and subsequently reducing S–phase gene expression in prostate cancer, The Prostate, 2007, 67, 9Direct Link:
- 11
- 12, , , , , TLR3 signaling in a hepatoma cell line is skewed towards apoptosis, Journal of Cellular Biochemistry, 2007, 100, 5Direct Link:
- 13, , Targeting GSK-3: a promising approach for cancer therapy?, Future Oncology, 2006, 2, 1, 91
- 14, , , , , The Wnt signaling pathway has tumor suppressor properties in retinoblastoma, Biochemical and Biophysical Research Communications, 2006, 349, 1, 261

1097-0215/asset/olbannerleft.jpg?v=1&s=45719cd7de57873027993264fcc568b335a8cd56)
1097-0215/asset/olbannerright.jpg?v=1&s=5e0fba63c1309b3036eb9215a0e1e83dd02efd19)
