• 1
    Yang CS, Chen L, Lee MJ, Landau JM. Effects of tea on carcinogenesis in animal models and humans (edited under the auspices of the American Institute for Cancer Research). New York: Plenum Press, 1996. 5161.
  • 2
    Bickers DR, Athar M. Novel approach to cancer chemoprevention. Dermatol J 2000; 27: 6915.
  • 3
    Bushman JL. Green tea and cancer in humans: a review of the literature. Nutr Cancer 1998; 31: 1519.
  • 4
    Brown MD. Green tea (Camellia sinensis) extract and its possible role in the prevention of cancer. Altern Med Rev 1999; 4: 36070.
  • 5
    Yang CS, Wang ZY. Tea and cancer. J Natl Cancer Instit 1993; 85: 103849.
  • 6
    Katiyar SK, Mukhtar H. Tea antioxidants in cancer chemoprevention. J Cell Biochem 1997; 27: 5967.
  • 7
    Siddiqui IA, Afaq F, Adhami VM, Ahmad N, Mukhtar H. Antioxidants of the beverage tea in promotion of human health. Antioxid Redox Signal 2004; 6: 57182.
  • 8
    Katiyar SK, Mukhtar H. Tea and chemoprevention of cancer. Int J Oncol 1996; 8: 22138.
  • 9
    Lin JK, Liang YC. Cancer chemoprevention by tea polyphenols. Proc Natl Sci Counc Repub China B 2000; 24: 113.
  • 10
    Balentine DA. Manufacturing and chemistry of tea. In: HuangMT, HoCT, LeeCY, eds. Phenolic compounds in food and their effects on health. Washington DC: American Chemical Society, 1992. 10317.
  • 11
    Yang CS, Maliakal P, Meng X. Inhibition of carcinogenesis by tea. Annu Rev Pharmacol Toxicol 2002; 42: 2554.
  • 12
    Yang CS, Yang GY, Landau JM, Kim S, Liao J. Tea and tea polyphenols inhibit cell hyperproliferation, lung tumorigenesis, and tumor progression. Exp Lung Res 1998; 24: 62939.
  • 13
    Steele VE, Kelloff GJ, Balentine D, Boone CW, Mehta R, Bagheri D, Sigman CC, Zhu S, Sharma S. Comparative chemopreventive mechanisms of green tea, black tea and selected polyphenol extracts measured by in vitro bioassays. Carcinogenesis 2000; 21: 637.
  • 14
    Lin JK. Cancer chemoprevention by tea polyphenols through modulating signal transduction pathways. Arch Pharm Res 2002; 25: 56171.
  • 15
    Yang GY, Liao J, Li C, Chung J, Yurkow EJ, Ho CT, Yang CS. Effect of black and green tea polyphenols on c-jun phosphorylation and H(2)O(2) production in transformed and non-transformed human bronchial cell lines: possible mechanisms of cell growth inhibition and apoptosis induction. Carcinogenesis 2000; 21: 20359.
  • 16
    Okabe S, Ochiai Y, Aida M, Park K, Kim SJ, Nomura T, Suganuma M, Fujiki H. Mechanistic aspects of green tea as a cancer preventive: effect of components on human stomach cancer cell lines. Jpn J Cancer Res 1999; 90: 7339.
  • 17
    Lung HL, Ip WK, Chen ZY, Mak NK, Leung KN. Comparative study of the growth-inhibitory and apoptosis-inducing activities of black tea theaflavins and green tea catechin on murine myeloid leukemia cells. Int J Mol Med 2004; 13: 46571.
  • 18
    Weisburger JH, Rivenson A, Aliaga C, Reinhardt J, Kelloff GJ, Boone CW, Steele VE, Balentine DA, Pittman B, Zang E. Effect of tea extracts, polyphenols, and epigallocatechin gallate on azoxymethane-induced colon cancer. Exp Lung Res 1998; 24: 62939.
  • 19
    Sarkar A, Bhaduri A. Black tea is a powerful chemopreventor of reactive oxygen and nitrogen species: comparison with its individual catechin constituents and green tea. Biochem Biophys Res Commun 2001; 284: 1738.
  • 20
    Bhattacharyya A, Choudhuri T, Pal S, Chattopadhyay S, Datta GK, Sa G, Das T. Apoptogenic Effects Of Black Tea On Ehrlich's Ascites Carcinoma Cell. Carcinogenesis 2003; 24: 7580.
  • 21
    Marchetti P, Castedo M, Susin SA, Zamzami N, Hirsch T, Macho A, Haeffner A, Hirsch F, Geuskens M, Kroemer G. Mitochondrial permeability transition is a central coordinating event of apoptosis. J Exp Med 1996; 184: 115560.
  • 22
    Green DR, Reed JC. Mitochondria and apoptosis. Science 1998; 281: 130912.
  • 23
    Pallis M, Grundy M, Turzanski J, Kofler R, Russell N. Mitochondrial membrane sensitivity to depolarization in acute myeloblastic leukemia is associated with spontaneous in vitro apoptosis, wild-type TP53, and vicinal thiol/disulfide status. Blood 2001; 98: 40513.
  • 24
    Hirsch T, Marchetti P, Susin SA, Dallaporta B, Zamzami N, Marzo I, Geuskens M, Kroemer G. The apoptosis-necrosis paradox. Apoptogenic proteases activated after mitochondrial permeability transition determine the mode of cell death. Oncogene. 1997; 15: 157381.
  • 25
    Wetzel EB, Green DR. Caspases induce cytochrome c release from mitochondria by activating cytosolic factors. J Biol Chem 1997; 274: 1748490.
  • 26
    Chao DT, Korsmeyer SJ. Bcl-2 family: Regulators of cell death. Ann Rev Immunol 1998; 16: 395419.
  • 27
    Gross A, McDonnell JM, Korsmeyer SJ. BCL-2 family members and the mitochondria in apoptosis. Genes Dev 1999; 13: 1899911.
  • 28
    Kroemer G. The proto-oncogene bcl-2 and its role in regulating apoptosis. Nat Med 1997; 3: 61420.
  • 29
    Kim TH, Zhao Y, Barber MJ, Kuharsky DK, Yin XM. Bid-induced cytochrome c release is mediated by a pathway independent of mitochondrial permeability transition pore and Bax. J Biol Chem. 2000; 275: 3947481.
  • 30
    Marzo I, Brenner C, Zamzami N, Jurgensmeier J M, Susin SA, Vieira HL, Prevost MC, Xie Z, Matsuyama S, Reed JC, Kroemer G. Bax and adenine nucleotide translocator cooperate in the mitochondrial control of apoptosis. Science 1998; 281: 202731.
  • 31
    Shimizu S, Narita M, Tsujimoto Y. Bcl-2 family proteins regulate the release of apoptogenic cytochrome c by the mitochondrial channel VDAC. Nature 1999; 399: 4837.
  • 32
    Narita M, Shimizu S, Ito T, Chittenden T, Lutz RJ, Matsuda H, Tsujimoto Y. Bax interacts with the permeability transition pore to induce permeability transition and cytochrome c release in isolated mitochondria. Proc Natl Acad Sci U S A 1998; 95: 146816.
  • 33
    Zamzami N, Marchetti P, Castedo M, Decaudin D, Macho A, Hirsch T, Susin SA, Petit PX, Mignotte B, Kroemer G. Sequential reduction of mitochondrial transmembrane potential and generation of reactive oxygen species in early programmed cell death. J Exp Med. 1995; 182: 36777.
  • 34
    Karpinich NO, Tafani M, Rothman RJ, Russo MA, Farber JL. The course of etoposide-induced apoptosis from damage to DNA and p53 activation to mitochondrial release of cytochrome c. J Biol Chem 2002; 277: 654752.
  • 35
    Finucane DM, Wetzel EB, Waterhouse NJ, Cotteri TG, Green D. Bax-induced caspase activation and apoptosis via cytochrome c release from mitochondria is inhibitable by Bcl-xL. J Biol Chem 1999; 274: 222533.
  • 36
    Hirpara JL, Seyed MA, Loh KW, Dong H, Kini RM, Pervaiz S. Induction of mitochondrial permeability transition and cytochrome C release in the absence of caspase activation is insufficient for effective apoptosis in human leukemia cells. Blood 2000; 95: 177380.
  • 37
    Induction of mitochondrial permeability transition and cytochrome C release in the absence of caspase activation is insufficient for effective apoptosis in human leukemia cells. Blood. 2000; 95: 177380.
  • 38
    Petronilli V, Cola C, Massari S, Colonna R, Bernardi P. Physiological effectors modify voltage sensing by the cyclosporin A-sensitive permeability transition pore of mitochondria. J Biol Chem 1993; 268: 2193945.
  • 39
    Pennington RJ. Biochemistry of dystrophic muscle: mitochondrial succinate-tetrazolium reductase and adenosine triphosphatase. Biochem J 1961; 80: 64954.
  • 40
    Sa G, Hitomi M, Harwalkar J, Stacey AW, Chen GC, Stacey DW. Ras is active throughout the cell cycle, but is able to induce cyclin D1 only during G2 phase. Cell Cycle 2002; 1: 508.
  • 41
    Pervaiz S, Seyed MA, Hirpara JL, Clément MV, Loh KW. Purified photoproducts of merocyanine 540 trigger cytochrome c release and caspase 8-dependent apoptosis in human leukemia and melanoma cells. Blood 1999; 93: 4096108.
  • 42
    Wetzel EB, Green DR. Apoptosis: checkpoint at the mitochondrial frontier. Mutation Res 1999; 434: 24351.
  • 43
    Halestrap AP. The regulation of the matrix volume of mammalian mitochondria in vivo and in vitro and its role in the control of mitochondrial metabolism. Biochim Biophys Acta 1989; 973: 35582.
  • 44
    Eskes R, Desagher S, Antonsson B, Martinou JC. Bid induces the oligomerization and insertion of Bax into the outer mitochondrial membrane. Mol Cell Biol 2000; 20: 92935.
  • 45
    Amadori D, Frassineti GL, De Matteis A., Mustacchi G, Santoro A, Cariello S, Ferrari M, Nascimben O, Nanni O, Lombardi A, Scarpi E, Zoli W. Modulating effect of lonidamine on response to doxorubicin in metastatic breast cancer patients: results from a multicenter prospective randomized trial. Breast Cancer Res Treat 1998; 49: 20917.
  • 46
    Das T, Sa G, Chattopadhyay S, Ray PK. Protein A-induced apoptosis of cancer cells is effected by soluble immune mediators. Cancer Immunol Immunother 2002; 51: 7680.
  • 47
    Pastorino JG, Tafani M, Rothman RJ, Marcinkeviciute A, Hoek JB, Farber JL, Marcineviciute A. Functional consequences of the sustained or transient activation by Bax of the mitochondrial permeability transition pore. J Biol Chem 1999; 274: 3173439.
  • 48
    Gogvadze V, Robertson JD, Zhivotovsky B, Orrenius S. Cytochrome c release occurs via Ca2+-dependent and Ca2+-independent mechanisms that are regulated by Bax. J Biol Chem. 2001; 276: 1906671.
  • 49
    Li PF, Dietz R, Harsdorf VR. p53 regulates mitochondrial membrane potential through reactive oxygen species and induces cytochrome c-independent apoptosis blocked by Bcl-2. EMBO J. 1999; 18: 602736.
  • 50
    Eskes R, Antonsson B, Osen-Sand A, Montessuit S, Richter C, Sadoul R, Mazzei G, Nichols A, Martinou JC. Bax-induced cytochrome C release from mitochondria is independent of the permeability transition pore but highly dependent on Mg2+ ions. J Cell Biol. 1998; 143: 21724.
  • 51
    Bharti AC, Singh SM. Induction of apoptosis in bone marrow cells by gangliosides produced by a T cell lymphoma. Immunol Lett 2000; 72: 3948.
  • 52
    Ott M, Robertson JD, Gogvadez V, Zhivotovsky B, Orrenius S. Cytochrome c release from mitochondria proceeds by a two-step process. Proc Natl Acad Sci U S A 2002; 99: 125963.
  • 53
    Krajewski S, Krajewska M, Ellerby LM, Welsh K, Xie Z, Deveraux QL, Salvesen GS, Bredesen DE, Rosenthal RE, Fiskum G, Reed JC. Release of caspase-9 from mitochondria during neuronal apoptosis and cerebral ischemia. Proc Natl Acad Sci U S A 1999; 96: 57527.
  • 54
    Susin SA, Lorenzo HK, Zamzami N, Marzo I, Brenner C, Larochette N, Prevost MC, Alzari PM, Kroemer G. Mitochondrial release of caspase-2 and -9 during the apoptotic process. J Exp Med 1999; 189: 38194.
  • 55
    Jiang C, Wang Z, Ganther H, Lu J. Caspases as key executors of methyl selenium-induced apoptosis (anoikis) of du-145 prostate cancer cells. Cancer Res 2001; 61: 306270.
  • 56
    Susin SA, Zamzami N, Castedo M, Hirsch T, Marchetti P, Macho A, Daugas E, Geuskens M, Kroemer G. Bcl-2 inhibits the mitochondrial release of an apoptogenic protease. J Exp Med 1996; 184: 133141.